Aurothioglucose inhibits murine thioredoxin reductase activity in vivo

Journal of Nutrition

Volumn 129, Issue 1, 1999, Pages 194-198

  Smith, Allen D ^a   Guidry, Catherine A ^a   Morris, Virginia C ^a   Levander, Orville A ^a  

^a BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

Author keywords

Aurothioglucose; Glutathione peroxidase; Mice; Selenium; Thioredoxin reductase

Indexed keywords

AUROTHIOGLUCOSE; GLUTATHIONE PEROXIDASE; SELENOCYSTEINE; THIOREDOXIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; HEART; IN VIVO STUDY; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS; VIRUS VIRULENCE;

ANIMALIA; COXSACKIEVIRUS; MURINAE;

EID: 0032900912     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.1.194     Document Type: Article

References (41)

1. Allner, K., Bradish, C. J., Fitzgeorge, R. & Nathanson, N. (1974) Modification by sodium auro-thio-malate of the expression of virulence in mice by defined strains of Semliki Forest virus. J. Gen. Virol. 24: 221-228.
2. Arnér, E.S.J., Nordberg, J. & Holmgren, A. (1996) Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. Biochem. Biophys. Res. Commun. 225: 268-274.
3. Atkins H. L., Lambrecht, T. M., Wolf, A. P., Ansari, A. N. & Guillaume, M. (1975) Distribution of various labeled thioglucoses in rodents. Radiology 11: 723-725.
4. Baker, M. A., Dillard, C. J. & Tappel, A. L. (1985) Effect of gold on selenium and glutathione peroxidase activities in rat tissues. Drug-Nutr. Interact. 3: 141-152.
5. Beck, M. A., Kolbeck, P. C., Rohr, L. H., Shi, Q., Morris, V. C. & Levander, O. A. (1994a) Benign human enterovirus becomes virulent in selenium-deficient mice. J. Med. Virol. 43: 166-170.
6. Beck, M. A., Kolbeck, P. C., Rohr, L. H., Shi, Q., Morris, V. C. & Levander, O. A. (1994b) Vitamin E deficiency intensifies the myocardial injury of Coxsackievirus B3 infection of mice. J. Nutr. 124: 345-358.
7. Beck, M. A., Kolbeck, P. C., Shi, Q., Rohr, L. H., Morris, V. C. & Levander, O. A. (1994c) Increased virulence of a human enterovirus (coxsackievirus B3) in selenium-deficient mice. J. Infect. Dis. 170: 351-357.
8. Beck, M. A., Shi, Q., Morris, V. C. & Levander, O. A. (1995) Rapid genomic evolution of a non-virulent coxsackievirus B3 in selenium-deficient mice results in selection of identical virulent isolates. Nat. Med. 1: 433-436.
9. Berry, M. J., Kedffer, J. D., Harney, J. W. & Larsen, P. R. (1991) Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J. Biol. Chem. 266: 14155-14158.
10. Björnstedt, M., Hamberg, M., Kumar, S., Xue, J. & Holmgren, A. (1995) Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocysteine strongly stimulates the reaction via catalytically generated selenols. J. Biol. Chem. 270: 11761-11764.
11. Björnstedt, M., Kumar, S., Björkhem, L., Spyrou, G. & Holmgren, A. (1997) Selenium and the thioredoxin and glutaredoxin systems. Biomed. Environ. Sci. 10: 271-279.
12. Blocka, K. L., Paulus, H. E. & Furst, D. E. (1986) Clinical pharmacokinetics of oral and injectable gold compounds. Clin. Pharmacokinet. 11: 133-143.
13. Bradish, C. J., Allner, K. & Fitzgeorge, R. (1975) Immunomodification and the expression of virulence in mice by defined strains of Semliki Forest virus: the effects of myocrisin and I-asparaginase. J. Gen. Virol. 28: 239-250.
14. Brecher, G. & Waxler, S. H. (1949) Obesity in albino mice due to single injection of goldthioglucose. Proc. Soc. Exp. Biol. Med. 70: 498-501.
15. Chaudiere, J. & Tappel, A. L. (1984) Interaction of gold (I) with the active site of selenium-glutathione peroxidase. J. Inorg. Biochem. 20: 313-325.
16. Croteau, W., Whittemore, S. L., Schneider, M. J. & St. Germain, D. L. (1995) Cloning and expression of a cDNA for a mammalian type III iodothyronine deiodinase. J. Biol. Chem. 270: 16569-16575.
17. De Laey, P., Dent, C., Terry, A. C. & Quinn, E. H. (1974) Gold thioglucose, its toxicity and efficacy in Chartes River mice. Arch. Int. Pharmacodyn. 211: 341-362.
18. Dillard, C. J. & Tappel, A. L. (1986) Are some major in vivo effects of gold related to microenvironments of decreased selenium? Med. Hypotheses 20: 407-420.
19. Edelman, P. M., Schwarts, I. L., Cronkite, E. P., Brecher, G. & Livingston, L. (1965) The effect of hyperglycemia on hypothalamic gold uptake and hyperphagia in goldthioglucose-treated mice. J. Exp. Med. 121: 403-413.
20. Hill, K. E., McCollum, G. W., Boeglin, M. E. & Burk, R. F. (1997a) Thioredoxin reductase activity is decreased by selenium deficiency. Biochem. Biophys. Res. Commun. 234: 293-295.
21. Hill, K. E., McCollum, G. W. & Burk, R. F. (1997b) Determination of thioredoxin reductase activity in rat liver supernatant. Anal. Biochem. 253: 123-125.
22. Holmgren, A. (1977) Bovine thioredoxin system: purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction. J. Biol. Chem. 252: 4600-4606.
23. Hu, M.-L., Dillard, C. J. & Tappel, A. L. (1988) Aurothioglucose effect on sulfhydryls and glutathione-metabolizing enzymes: in vivo inhibition of selenium-dependent glutathione peroxidase. Res. Commun. Chem. Pathol. Pharmacol. 59: 147-160.
24. Kabiri, M., Basiri, E. & Kadivar, D. (1978) Potentiation of coxsackievirus B3 infection in adult mice pretreated with a gold salt. J. Med. Virol. 3: 125-136.
25. Larsson, S. (1967) Factors of importance for the etiology of obesity in mice. Acta Physiol. Scand. (suppl.) 294: 1-82.
26. Levander, O. A. & Beck, M. A. (1997) Interacting nutritional and infectious etiologies of Keshan disease. Insights from coxsackievirus B-induced myocarditis in mice deficient in selenium or vitamin E. Biol. Trace Elem. Res 56: 5-21.
27. Levander, O. A., DeLoach, D. P., Morris, V. C. & Moser, P. B. (1983) Platelet glutathione peroxidase activity as an index of selenium status in rats. J. Nutr. 113:55-63.
28. Liebelt, R. A., Sebika, K., Liebelt, A. G. & Perry, J. H. (1960) Genetic susceptibility to goldthioglucose-induced obesity in mice. Proc. Soc. Exp. Biol. N.Y. 104: 689-692.
29. Malaisse, W. J. (1982) Alloxan toxicity to the pancreatic B-cell. A new hypothesis. Biochem. Pharmacol. 31: 3527-3534.
30. May, J. M., Mendiratta, S., Hill, K. E. & Burk, R. F. (1997) Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase. J. Biol. Chem. 272: 22607-22610.
31. McAdam, P. A., Morris, V. C. & Levander, O. A. (1984) Automated determination of glutathione peroxidase (GSH-Px) activity in tissues from rats of different selenium (Se) status. Fed. Proc. 43: 867 (abs.).
32. 2G mice infected with togaviruses and flaviviruses. J. Gen. Virol. 68: 2665-2668.
33. Reamer, D. C. & Veillon, C. (1981) Determination of selenium in biological materials by stable isotope dilution gas chromatography-mass spectrometry. Anal. Chem. 53: 2166-2169.
34. Reglinski, J., Paterson D. E., Latimer, S., Campbell, J. M., Wilson, R., Porter, D., Sturrock, R. D. & Smith, W. E. (1997) Myocrisin-mediated oxidative stress. Clin. Chem. Acta 268: 85-99.
35. Salvatore, D., Bartha, T., Hamey, J. W. & Larsen, P. R. (1996) Molecular biological and biochemical characterization of the human type 2 selenodeiodinase. Endocrinology 137: 3308-3315.
36. Smith, P. K. (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85.
37. Soyka L. F., Haessler H. A. & Crawford J. D. (1969) Altered composition and lipolysis of adipose tissue from gold thioglucose obese mice. Am. J. Physiol. 217: 1088-1093.
38. Stebbing, N., Dawson, K. M. & Lindley, I.J.D. (1978) Requirement for macrophages for interferon to be effective against encephalomyocarditis virus infection of mice. Infect. Immun. 19: 5-11.
39. St. Germain, D. L., Schwartzman, R. A., Croteau, W., Kanamori, A., Wang, Z., Brown, D. D. & Galton, V. A. (1994) A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase. Proc. Natl. Acad. Sci. U.S.A. 91: 7767-7771.
40. Tamura, T. & Stadtman, T. C. (1996) A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity. Proc. Natl. Acad. Sci. U.S.A. 93: 1006-1011.
41. Tiedge, M., Lortz, S., Drinkgem, J. & Lenzen, S. (1997) Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes 46: 1733-1742.