Redox signaling: Hydrogen peroxide as intracellular messenger

Experimental and Molecular Medicine

Volumn 31, Issue 2, 1999, Pages 53-59

  Rhee, Sue Goo ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Hydrogen peroxide; Redox; ROS; Signaling

Indexed keywords

HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

CELL LEVEL; CELLULAR DISTRIBUTION; MAMMAL CELL; OXIDATION REDUCTION REACTION; REVIEW; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 0001952829     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.1999.9     Document Type: Review

References (62)

1. Bae, Y. S., Kang, S. W., Seo, M. S., Baines, I. C., Tekle, E., Chock, P. B., and Rhee, S. G. (1997) Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine Phosphorylation. J. Biol. Chem. 272: 217-221
2. Baeuerle, P. A. And Baltimore, D. (1996) NF-kappa B: ten years after. Cell 87, 13-20
3. Chae, H. Z., Chung, S. J. and Rhee, S. G. (1994) Thioredoxin-dependent peroxide reductase from yeast. J. Biol. Chem. 269: 27670-27678
4. Chae, H. Z., Kim, I.-H., Kim, K. and. Rhee, S. G (1993) Cloning, sequencing, and mutation of thiol-specific antioxidant gene of Saccharomyces cerevisiae. J. Biol. Chem. 268: 16815-16821
5. Chae, H. Z., Robinson, K. Poole, L. B., Church, G., Storz, G. and Rhee, S. G. (1994) Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes. Proc. Natl. Acad. Sci. USA 91: 7017-7021
6. Chae, H. Z., Uhm, T. B. and Rhee, S. G. (1994) Dimerization of thiol-specific antioxidant and the essential role of cysteine 47. Proc. Natl. Acad. Sci. USA 91: 7022-7026
7. Chen, Q., Olashaw, N. and Wu, J. (1995) Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase kinase activation pathway. J. Biol. Chem. 270: 28499-28502
8. Chen, Z., Silva, H. and Klessing, D. F. (1993) Active oxygen species in the induction of plant systemic acquired resistance by salicylic acid. Science 262: 1883-1886
9. Choi, H.-J., Kang, S. W., Yang, C.-H., Rhee, S. G. and Ryu, S.-E. (1998) Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution. Nature Struc. Biol. 5: 400-406
10. Finkel, T. (1998) Oxygen radicals and signaling. Curr. Opinion Cell Biol. 10: 248-253
11. Freedman, R. B., Hirst, T. R. and Tuite, M. F. (1994) Protein disulphide isomerase: building bridges in protein folding. Trends. Biochem. Sci. 19: 331-336
12. Griendling, K. K., Minieri, C. A., Ollerenshaw, J. D. and Alexander, R. W. (1994) Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 74: 1141-1148
13. Hanks, S. and Quinn, M. (1991) Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Method Enzymol 200: 38-62
14. 2 and vanadate in vitro. Biochem. Biophys. Res. Commun. 188: 773-779
15. Hidalgo, E., Ding, H., and Demple, B. (1997) Redox signal transduction: mutations shifting [2Fe-2S] centers of the SoxR sensor-regulator to the oxidized form. Cell 88: 121-129
16. Holmgren, A. (1989) Thioredoxin and glutaredoxin systems. J. Biol. Chem. 264: 13963-13966
17. Huie, R. E. and Padmaja, S. (1993) The reaction of no with superoxide. Free Radical Res. Commun. 18: 195-199
18. Ischiropoulos, H. (1998) Living and dying with reactive species. Focus on "peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease". Am. J. Physiol. 274: C8534
19. Jacobson, M. (1996) Reactive oxygen species and programmed cell death. Trends in Biochem. Sci. 21, 83-86
20. Jin, D.-Y., Chae, H. Z., Rhee, S. G. and Jeang, K.-T. (1997) Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation. J. Biol. Chem. 272: 30952-30961
21. Kang, S. W., Baines, I. C. and Rhee, S. G. (1998) Characterization of a mammalian peroxiredoxin that contains one conserved cysteine. J. Biol. Chem. 273: 6303-6311
22. Kang, S. W., Chae, H. Z., Seo, M. S., Kim, K., Baines, I. C. and Rhee, S. G. (1998) Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha J. Biol. Chem. 273: 6297-6302
23. 2 mixed-function oxidation system. J. Biol. Chem. 263: 4704-4711
24. Knebel, A., Rahmsdorf, H. J., Ullrich, A., and Herrlich, P. (1996) Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 15: 5314-5325
25. 2. Proc. Natl. Acad. Sci. USA 94: 11233-11237
26. Kourie, J. I. (1998) Interaction of reactive oxygen species with ion transport mechanisms. Am. J. Physiol. 275: C1-24
27. Kretz-Remy, C., Mehlen, P., Mirault, M.-E. and Arrigo, A.-P. (1996) Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression. J. Cell. Biol. 133: 1083-1093
28. 2 generation in 3T3 L1-cells. Biochem J. 307: 549-556
29. Lander, H. M., Milbank, A. J., Tauras, J. M., Hajjar, D. P., Hempstead, B. L., Schwartz, G. D., Kraemer, T. T., Mirza, U. A., Chait, B. T., Campbell-Burk, S. and Quilliam, L. A. (1996) Redox regulation of cell signalling, Nature 381: 380-381
30. Lee, S.-R., Kwon K.-S., Kim, S.-R. and Rhee, S. G. (1998) Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273: 15366-15372
31. Lee, S. R., Kwon, K.-S., Kim, S.-R. and Rhee, S. G. (1998) Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273: 15366-15372
32. 2 in Rat-2 fibroblasts. J. Biol. Chem. 273: 12710-12715
33. 2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell 79: 583-590
34. Levine, R. L., Mosoni, L., Berlett, B. S. and Stadtman, E. R. (1996) Methionine residues as endogenous antioxidants in proteins. Proc. Natl. Acad. Sci. USA 93: 15036-15040
35. 2- terminal kinases, J. Biol. Chem. 271: 15703-15707
36. Lohse, D. L., Denu, J. M., Santoro, N. and Dixon, J. E. (1997) Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1, Biochemsitry 36: 4568-4575
37. May, J. M. and De Haen, C. (1979) The insulin-like effect of hydrogen peroxide on pathways of lipid synthesis in rat adipocytes. J. Biol. Chem. 254: 9017-9021
38. Meier, B., Radeke, H. H., Selle, S., Younes, M., Sies, H., Resch, K. and Habermehl, G. G. (1989) Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. Biochem J. 263: 539-545
39. Min, D. S., Kim, E. -G. and Exton, J. H.(1998) Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H202 in Swiss 3T3 fibroblasts. J. Biol. Chem. 273: 29986-29994
40. Moncada, S., Palmer, R. M. J. and Higgs, E. A. (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142
41. Natarajan, V., Taher, M. M., Roehm, B., Parinadi, N. L., Schmid, H. H. O., Kiss, Z. and Garcia, J. G. N. (1993) Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide. J. Biol. Chem. 268: 930-937
42. Ohba, M., Shibanum, M., Kuroki, K. and Nose, K. (1994) Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J. Cell Biol. 126: 1079-1088
43. Pahl, H. C. and Baeuerle, P. A. (1994) Oxygen and the control of gene expression. BioEssays 16: 497-501
44. Robertson, F. M., Beavis, A. J., Oberyszyn, T. M., O'Conell, S. M., Dokidos, A., Laskin, D.L., Laskin, J. D. and Reiners, J. J. Jr. (1990) Production of hydrogen peroxide by murine epidermal keratinocytes following treatment with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 50: 6062-6067
45. Rosner, J. L. and Storz, G. (1997) Regulation of bacterial responses to oxidative stress. Curr. Top. Cell Regul. 35: 163-177
46. Runge M. et al., unpublished work
47. Schreck, R., Rieber, R. and Baeuerele, P. A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10: 2247-2258
48. Schreck, R., Rieber, P. and Baeuerle, P. A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10: 2247-2258
49. Shirasu, K., Dixon, R. A. and Lamb, C. (1996) Signal transduction in plant immunity. Immunology 8: 3-7
50. Stadtman, E. R. and Oliver, C. N. (1991) Metal-catalyzed oxidation of proteins. Physiological consequences. J. Biol. Chem. 266: 2005-2008
51. Stadtman, E. R. and Berlett, B. S. (1998) Reactive oxygen-mediated protein oxidation in aging and disease. Drug Metabolism Reviews 30: 225-243
52. Sullivan, S. G., Chiu, D. T.-Y., Errasfa, M., Wang, J. M., Qi, J.-S. and Stem, A. (1994) Effects of H202 on protein tyrosine phosphatase activity in HER14 cells. Free Radical Biol. Med. 16: 399-403
53. 2 for platelet-derived growth factor signal transduction. Science 270: 296-299
54. Sundaresan, M., Yu, Z. X., Ferrans, V. J., Sulciner, D. J., Gutkind, J. S., Irani, K., Goldschmidt-Clermont, P. J. and Finkel, T. (1996) Regulation of reactive-oxygen-species generation in fibroblasts by Rac1. Biochem J. 318: 379-382
55. Suzuki, Y. J., Forman, H. J. and Sevanian, A. (1997) Oxidants as stimulators of signal transduction. Free Rad. Biol. and Med. 22, 269-285
56. 2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1. J. Biol. Chem. 270: 30334-30338
57. Thelen, M., Dewald, B. and Baggiolini, M. (1993) Neutrophil signal transduction and activation of the respiratory burst. Physiol. Rev. 73: 797-821
58. Ushio-Fukai, M., Zafari, A. M., Fukui, T., Ishizaka, N. and Griendling, K. K.. (1996) p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol. Chem. 271: 23317-23321
59. Yim, M. B., Chae, H. Z., Rhee, S. G., Chock, P. B. and Stadtman, E. R. (1994) On the protective mechanism of the thiol-specific antioxidant enzyme against the oxidative damage of biomacromolecules. J. Biol. Chem. 269: 1621-1626
60. Zhang, P., Liu, P., Kang, S. W., Seo, M. S., Rhee S. G. and Obeid, L. M. (1997) Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2. J. Biol. Chem. 272: 30615-30618
61. Zheng M., Slund F. and Storz G. (1998) Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279: 1718-1721
62. Zor, U., Ferber, E., Gergely, P., Szcs, K., Dormbradi, V. and Goldman, R. (1993) Reactive oxygen species mediate phorbol ester-regulated tyrosine phosphorylation and phospholipase A2 activation: potentiation by vanadate. Biochem. J. 295: 879-888