메뉴 건너뛰기




Volumn 90, Issue 4, 1999, Pages 1483-1492

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis; AR R 17,477; Copper zinc superoxide dismutase; Nitric oxide; Peroxynitrite; Transgenic mice

Indexed keywords

7 NITROINDAZOLE; COPPER ZINC SUPEROXIDE DISMUTASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

EID: 0032954386     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00492-8     Document Type: Article
Times cited : (73)

References (69)
  • 1
    • 0028971936 scopus 로고
    • Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis
    • Abe K., Pan L. H., Watanabe M., Kato T., Itoyama Y. Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. Neurosci. Lett. 199:1995;152-154.
    • (1995) Neurosci. Lett. , vol.199 , pp. 152-154
    • Abe, K.1    Pan, L.H.2    Watanabe, M.3    Kato, T.4    Itoyama, Y.5
  • 6
    • 0028584148 scopus 로고
    • Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration
    • Beckman J. S., Chen J., Crow J. P., Ye Y. Z. Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. Prog. Brain Res. 103:1994;371-380.
    • (1994) Prog. Brain Res. , vol.103 , pp. 371-380
    • Beckman, J.S.1    Chen, J.2    Crow, J.P.3    Ye, Y.Z.4
  • 8
    • 0028813380 scopus 로고
    • Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function
    • Borchelt D. R., Guarnieri M., Wong P. C., Lee M. K., Slunt H. S., Xu Z. S., Sisodia S. S., Price D. L., Cleveland D. W. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. J. biol. Chem. 70:1995;3234-3238.
    • (1995) J. Biol. Chem. , vol.70 , pp. 3234-3238
    • Borchelt, D.R.1    Guarnieri, M.2    Wong, P.C.3    Lee, M.K.4    Slunt, H.S.5    Xu, Z.S.6    Sisodia, S.S.7    Price, D.L.8    Cleveland, D.W.9
  • 9
    • 0025191219 scopus 로고
    • Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme
    • Bredt D. S., Snyder S. H. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. natn. Acad. Sci. U.S.A. 87:1990;682-685.
    • (1990) Proc. Natn. Acad. Sci. U.S.A. , vol.87 , pp. 682-685
    • Bredt, D.S.1    Snyder, S.H.2
  • 10
    • 0027975453 scopus 로고
    • Nitric oxide: A physiologic messenger molecule
    • Bredt D. S., Snyder S. H. Nitric oxide: a physiologic messenger molecule. A. Rev. Biochem. 63:1994;175-195.
    • (1994) A. Rev. Biochem. , vol.63 , pp. 175-195
    • Bredt, D.S.1    Snyder, S.H.2
  • 13
    • 0030806228 scopus 로고    scopus 로고
    • Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
    • Bruijn L. I., Beal M. F., Becher M. W., Schulz J. B., Wong P. C., Price D. L., Cleveland D. W. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proc. natn. Acad. Sci. U.S.A. 94:1997;7606-7611.
    • (1997) Proc. Natn. Acad. Sci. U.S.A. , vol.94 , pp. 7606-7611
    • Bruijn, L.I.1    Beal, M.F.2    Becher, M.W.3    Schulz, J.B.4    Wong, P.C.5    Price, D.L.6    Cleveland, D.W.7
  • 16
    • 0029073807 scopus 로고
    • The role of peroxynitrite in nitric oxide-mediated toxicity
    • Crow J. P., Beckman J. S. The role of peroxynitrite in nitric oxide-mediated toxicity. Curr. Top. Microbiol. Immun. 196:1995;57-73.
    • (1995) Curr. Top. Microbiol. Immun. , vol.196 , pp. 57-73
    • Crow, J.P.1    Beckman, J.S.2
  • 17
    • 1842289165 scopus 로고    scopus 로고
    • Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L
    • Crow J. P., Ye Y. Z., Strong M., Kirk M., Barnes S., Beckman J. S. Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L. J. Neurochem. 69:1997;1945-1953.
    • (1997) J. Neurochem. , vol.69 , pp. 1945-1953
    • Crow, J.P.1    Ye, Y.Z.2    Strong, M.3    Kirk, M.4    Barnes, S.5    Beckman, J.S.6
  • 18
    • 0030833449 scopus 로고    scopus 로고
    • Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite
    • Crow J. P., Sampson J. B., Zhuang Y., Thompson J. A., Beckman J. S. Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. J. Neurochem. 69:1997;1936-1944.
    • (1997) J. Neurochem. , vol.69 , pp. 1936-1944
    • Crow, J.P.1    Sampson, J.B.2    Zhuang, Y.3    Thompson, J.A.4    Beckman, J.S.5
  • 20
    • 0028674890 scopus 로고
    • Nitric oxide and focal cerebral ischemia: Multiplicity of actions and diverse outcome
    • Dawson D. A. Nitric oxide and focal cerebral ischemia: multiplicity of actions and diverse outcome. Cerebrovasc. Brain Metab. Rev. 6:1994;299-324.
    • (1994) Cerebrovasc. Brain Metab. Rev. , vol.6 , pp. 299-324
    • Dawson, D.A.1
  • 21
    • 0027939807 scopus 로고
    • Gases as biological messengers: Nitric oxide and carbon monoxide in the brain
    • Dawson T. M., Snyder S. H. Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J. Neurosci. 14:1994;5147-5159.
    • (1994) J. Neurosci. , vol.14 , pp. 5147-5159
    • Dawson, T.M.1    Snyder, S.H.2
  • 22
    • 0030065474 scopus 로고    scopus 로고
    • Free radicals and neuronal cell death
    • Dawson V. L., Dawson T. M. Free radicals and neuronal cell death. Cell Death Differ. 3:1996;71-78.
    • (1996) Cell Death Differ. , vol.3 , pp. 71-78
    • Dawson, V.L.1    Dawson, T.M.2
  • 23
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical neuronal cultures from neuronal nitric oxide synthase deficient mice
    • Dawson V. L., Kizushi V. M., Huang P. L., Snyder S. H., Dawson T. M. Resistance to neurotoxicity in cortical neuronal cultures from neuronal nitric oxide synthase deficient mice. J. Neurosci. 16:1996;2479-2487.
    • (1996) J. Neurosci. , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 25
    • 0028326424 scopus 로고
    • Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity
    • Dinerman J. L., Dawson T. M., Schell M. J., Snowman A., Snyder S. H. Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proc. natn. Acad. Sci. U.S.A. 91:1994;4214-4218.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 4214-4218
    • Dinerman, J.L.1    Dawson, T.M.2    Schell, M.J.3    Snowman, A.4    Snyder, S.H.5
  • 26
    • 0030914284 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase alternatively spliced forms: Prominent functional localizations in the brain
    • Eliasson M. J. L., Balackshaw S., Schell M. J., Snyder S. H. Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain. Proc. natn. Acad. Sci. U.S.A. 94:1997;3396-3401.
    • (1997) Proc. Natn. Acad. Sci. U.S.A. , vol.94 , pp. 3396-3401
    • Eliasson, M.J.L.1    Balackshaw, S.2    Schell, M.J.3    Snyder, S.H.4
  • 28
    • 0028200313 scopus 로고
    • Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines
    • Fujisawa H., Ogura T., Kurashima Y., Yokoyama T., Yamashita J., Esumi H. Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines. J. Neurochem. 3:1994;140-145.
    • (1994) J. Neurochem. , vol.3 , pp. 140-145
    • Fujisawa, H.1    Ogura, T.2    Kurashima, Y.3    Yokoyama, T.4    Yamashita, J.5    Esumi, H.6
  • 29
    • 0028917372 scopus 로고
    • Nitric oxide signaling in the central nervous system
    • Garthwaite J., Boulton C. L. Nitric oxide signaling in the central nervous system. A. Rev. Physiol. 57:1995;683-706.
    • (1995) A. Rev. Physiol. , vol.57 , pp. 683-706
    • Garthwaite, J.1    Boulton, C.L.2
  • 32
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney M. E., Cutting F. B., Zhai P., Doble A., Taylor C. P., Andrus P. K., Hall E. D. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol. 39:1996;147-157.
    • (1996) Ann. Neurol. , vol.39 , pp. 147-157
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 34
    • 0030862630 scopus 로고    scopus 로고
    • The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Hottinger A. F., Fine E. G., Gurney M. E., Zurn A. D., Aebischer P. The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. Eur. J. Neurosci. 9:1997;1548-1551.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1548-1551
    • Hottinger, A.F.1    Fine, E.G.2    Gurney, M.E.3    Zurn, A.D.4    Aebischer, P.5
  • 35
    • 0027769462 scopus 로고
    • Targeted disruption of the neuronal nitric oxide synthase gene
    • Huang P. L., Dawson T. M., Bredt D. S., Snyder S. H., Fishman M. C. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 75:1993;1273-1286.
    • (1993) Cell , vol.75 , pp. 1273-1286
    • Huang, P.L.1    Dawson, T.M.2    Bredt, D.S.3    Snyder, S.H.4    Fishman, M.C.5
  • 36
    • 0027945658 scopus 로고
    • Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
    • Huang Z., Huang P. L., Panahian N., Dalkara T., Fishman M. C., Moskowitz M. A. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 265:1994;1883-1885.
    • (1994) Science , vol.265 , pp. 1883-1885
    • Huang, Z.1    Huang, P.L.2    Panahian, N.3    Dalkara, T.4    Fishman, M.C.5    Moskowitz, M.A.6
  • 37
    • 0029294575 scopus 로고
    • Inducible nitric oxide synthase gene expression in brain following cerebral ischemia
    • Iadecola C., Zhang F., Xu S., Casey R., Ross M. E. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. cerebr. Blood Flow. Metab. 15:1995;378-384.
    • (1995) J. Cerebr. Blood Flow. Metab. , vol.15 , pp. 378-384
    • Iadecola, C.1    Zhang, F.2    Xu, S.3    Casey, R.4    Ross, M.E.5
  • 38
    • 0031020172 scopus 로고    scopus 로고
    • Bright and dark sides of nitric oxide in ischemic brain injury
    • Iadecola C. Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci. 20:1997;132-139.
    • (1997) Trends Neurosci. , vol.20 , pp. 132-139
    • Iadecola, C.1
  • 40
    • 0027363751 scopus 로고
    • Molecular evidence for nitric oxide-mediated motor neuron development
    • Kalb R. G., Agostini J. Molecular evidence for nitric oxide-mediated motor neuron development. Neuroscience. 57:1993;1-8.
    • (1993) Neuroscience , vol.57 , pp. 1-8
    • Kalb, R.G.1    Agostini, J.2
  • 41
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic V., Jackson-Lewis V., de Bilbao F., Dubois-Dauphin M., Przedborski S. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science. 277:1997;559-563.
    • (1997) Science , vol.277 , pp. 559-563
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 42
    • 0031012304 scopus 로고    scopus 로고
    • Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions
    • Kunst C. B., Mezey E., Brownstein M. J., Patterson D. Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions. Nature Genet. 15:1997;91-94.
    • (1997) Nature Genet. , vol.15 , pp. 91-94
    • Kunst, C.B.1    Mezey, E.2    Brownstein, M.J.3    Patterson, D.4
  • 43
    • 0029045416 scopus 로고
    • An evaluation of the nitric oxide/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture
    • Linden D. J., Dawson T. M., Dawson V. L. An evaluation of the nitric oxide/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture. J. Neurosci. 15:1995;5098-5105.
    • (1995) J. Neurosci. , vol.15 , pp. 5098-5105
    • Linden, D.J.1    Dawson, T.M.2    Dawson, V.L.3
  • 44
    • 0028026868 scopus 로고
    • Nitric oxide synthase: Aspects concerning structure and catalysis
    • Marletta M. A. Nitric oxide synthase: aspects concerning structure and catalysis. Cell. 78:1994;927-930.
    • (1994) Cell , vol.78 , pp. 927-930
    • Marletta, M.A.1
  • 45
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S., Higgs A. The L-arginine-nitric oxide pathway. New Engl. J. Med. 329:1993;2002-2012.
    • (1993) New Engl. J. Med. , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 47
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. Fedn Proc. Fedn Am. Socs exp. Biol. 6:1992;3051-3064.
    • (1992) Fedn Proc. Fedn Am. Socs Exp. Biol. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 48
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C., Xie Q. W. Nitric oxide synthases: roles, tolls, and controls. Cell. 78:1994;915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 52
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo C. A., Xu Z., Borchelt D. R., Price D. L., Sisodia S. S., Cleveland D. W. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc. natn. Acad. Sci. U.S.A. 92:1995;954-958.
    • (1995) Proc. Natn. Acad. Sci. U.S.A. , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3    Price, D.L.4    Sisodia, S.S.5    Cleveland, D.W.6
  • 53
    • 0029057332 scopus 로고
    • Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells
    • Peunova N., Enikolopov G. Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells. Nature. 375:1995;68-73.
    • (1995) Nature , vol.375 , pp. 68-73
    • Peunova, N.1    Enikolopov, G.2
  • 55
    • 0028915976 scopus 로고
    • Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: Studies in yeast and neural cells
    • Rabizadeh S., Gralla E. B., Borchelt D. R., Gwinn R., Valentine J. S., Sisodia S., Wong P., Lee M., Hahn H., Bredesen D. E. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proc. natn. Acad. Sci. U.S.A. 92:1995;3024-3028.
    • (1995) Proc. Natn. Acad. Sci. U.S.A. , vol.92 , pp. 3024-3028
    • Rabizadeh, S.1    Gralla, E.B.2    Borchelt, D.R.3    Gwinn, R.4    Valentine, J.S.5    Sisodia, S.6    Wong, P.7    Lee, M.8    Hahn, H.9    Bredesen, D.E.10
  • 58
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps M. E., Huntley G. W., Hof P. R., Morrison J. H., Gordon J. W. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. natn. Acad. Sci. U.S.A. 92:1995;689-693.
    • (1995) Proc. Natn. Acad. Sci. U.S.A. , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 60
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani A., Dawson T. M., Dawson V. L. Nitric oxide synthase in models of focal ischemia. Stroke. 28:1997;1283-1288.
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.1    Dawson, T.M.2    Dawson, V.L.3
  • 61
    • 0028796770 scopus 로고
    • Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
    • Schulz J. B., Matthews R. T., Muqit M. M., Browne S. E., Beal M. F. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. J. Neurochem. 64:1995;936-939.
    • (1995) J. Neurochem. , vol.64 , pp. 936-939
    • Schulz, J.B.1    Matthews, R.T.2    Muqit, M.M.3    Browne, S.E.4    Beal, M.F.5
  • 62
    • 0029933799 scopus 로고    scopus 로고
    • Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle
    • Silvagno F., Xia H., Bredt D. S. Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle. J. biol. Chem. 271:1996;11,204-11,208.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11
    • Silvagno, F.1    Xia, H.2    Bredt, D.S.3
  • 64
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W., Price D. L. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14:1995;1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 65
    • 0028881569 scopus 로고
    • Two closely linked but separable promoters for human neuronal nitric oxide synthase gene transcription
    • Xie J., Roddy P., Rife T. K., Murad F., Young A. P. T. Two closely linked but separable promoters for human neuronal nitric oxide synthase gene transcription. Proc. natn. Acad. Sci. U.S.A. 92:1995;1242-1246.
    • (1995) Proc. Natn. Acad. Sci. U.S.A. , vol.92 , pp. 1242-1246
    • Xie, J.1    Roddy, P.2    Rife, T.K.3    Murad, F.4    Young, A.P.T.5
  • 67
    • 0027942138 scopus 로고
    • The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels
    • Yoshida T., Limmroth V., Irikura K., Moskowitz M. A. The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J. cerebr. Blood Flow Metab. 14:1994;924-929.
    • (1994) J. Cerebr. Blood Flow Metab. , vol.14 , pp. 924-929
    • Yoshida, T.1    Limmroth, V.2    Irikura, K.3    Moskowitz, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.