Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP

Experimental Neurology

Volumn 167, Issue 1, 2001, Pages 189-195

  Andreassen, Ole A ^a   Ferrante, Robert J ^b   Dedeoglu, Alpaslan ^a   Albers, David W ^a,d   Klivenyi, Peter ^a   Carlson, Elaine J ^c   Epstein, Charles J ^c   Beal, M Flint ^a,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

3 nitropropionic acid; Free radicals; Huntington's disease; Malonate; MPTP; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 NITROPROPIONIC ACID; DOPAMINE; FREE RADICAL; HYDROXYL RADICAL; MALONIC ACID; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN SLICE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE PREDISPOSITION; ENZYME DEFICIENCY; HUNTINGTON CHOREA; KNOCKOUT MOUSE; MALE; MITOCHONDRIAL MYOPATHY; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0035155759     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7525     Document Type: Article

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