메뉴 건너뛰기




Volumn 155, Issue 2, 1999, Pages 243-251

Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis

Author keywords

Antioxidant; Aspirin; Behavior; Neuroprotection; Transgenic mice

Indexed keywords

ACETYLSALICYLIC ACID; LYSINE ACETYLSALICYLATE; RILUZOLE; SUPEROXIDE DISMUTASE;

EID: 0344609220     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6984     Document Type: Article
Times cited : (83)

References (44)
  • 1
    • 7144222278 scopus 로고    scopus 로고
    • Measurement of spinal cord lipid and protein oxidation in the transgenic mouse model of familial amyotrophic lateral sclerosis
    • Andrus P. K., Fleck T. J., Himes C. S., Gurney M. E., Hall E. D. Measurement of spinal cord lipid and protein oxidation in the transgenic mouse model of familial amyotrophic lateral sclerosis. Soc. Neurosci. Abs. 23:1997;729.12.
    • (1997) Soc. Neurosci. Abs. , vol.23 , pp. 72912
    • Andrus, P.K.1    Fleck, T.J.2    Himes, C.S.3    Gurney, M.E.4    Hall, E.D.5
  • 2
    • 0031661173 scopus 로고    scopus 로고
    • Aspirin and salicylate protect against MPTP induced dopamine depletion in mice
    • Aubin N., Carter C., Deffois A., Curet O. Aspirin and salicylate protect against MPTP induced dopamine depletion in mice. J. Neurochem. 1998.
    • (1998) J. Neurochem.
    • Aubin, N.1    Carter, C.2    Deffois, A.3    Curet, O.4
  • 3
    • 0031014470 scopus 로고    scopus 로고
    • Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis
    • Azzouz M., Leclerc N., Gurney M., Warter J. M., Poindron P., Borg J. Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis. Muscle Nerve. 20:1997;45-51.
    • (1997) Muscle Nerve , vol.20 , pp. 45-51
    • Azzouz, M.1    Leclerc, N.2    Gurney, M.3    Warter, J.M.4    Poindron, P.5    Borg, J.6
  • 7
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • Bensimon G., Lacomblez L., Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. N. Engl. J. Med. 330:1994;585-591.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 8
    • 0027359334 scopus 로고
    • Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
    • Bowling A. C., Schulz G. B., Brown R. H. J., Beal M. F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61:1993;2322-2325.
    • (1993) J. Neurochem. , vol.61 , pp. 2322-2325
    • Bowling, A.C.1    Schulz, G.B.2    Brown, R.H.J.3    Beal, M.F.4
  • 9
    • 0028960506 scopus 로고
    • Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice
    • Brown R. H. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell. 80:1995;687-692.
    • (1995) Cell , vol.80 , pp. 687-692
    • Brown, R.H.1
  • 10
    • 0030806228 scopus 로고    scopus 로고
    • Elevated free nitrotyrosine levels, but not protein-bond nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrantin vivo
    • Bruijn L. I., Beal M. F., Becher M. W., Schulz J. B., Wong P. C., Price D. L., Cleveland D. W. Elevated free nitrotyrosine levels, but not protein-bond nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrantin vivo. Proc. Natl. Acad. Sci. USA. 94:1997;7606-7611.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7606-7611
    • Bruijn, L.I.1    Beal, M.F.2    Becher, M.W.3    Schulz, J.B.4    Wong, P.C.5    Price, D.L.6    Cleveland, D.W.7
  • 11
    • 0028863291 scopus 로고
    • The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rhCNTF) in patients with amyotrophic lateral sclerosis: Relationship to parameters of the acute phase response
    • Cederbaum J. M. The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rhCNTF) in patients with amyotrophic lateral sclerosis: Relationship to parameters of the acute phase response. Clin. Neuropharmacol. 18:1995;500-514.
    • (1995) Clin. Neuropharmacol. , vol.18 , pp. 500-514
    • Cederbaum, J.M.1
  • 12
    • 0028788303 scopus 로고
    • A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis
    • Cederbaum J. M. A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. Clin. Neuropharmacol. 18:1995;515-532.
    • (1995) Clin. Neuropharmacol. , vol.18 , pp. 515-532
    • Cederbaum, J.M.1
  • 14
    • 0026698273 scopus 로고
    • Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+
    • Chiueh C. C., Krishna G., Tulsi P., Obata T., Lang K., Huang S. J., Murphy D. L. Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+. Free Rad. Biol. Med. 13:1992;581-583.
    • (1992) Free Rad. Biol. Med. , vol.13 , pp. 581-583
    • Chiueh, C.C.1    Krishna, G.2    Tulsi, P.3    Obata, T.4    Lang, K.5    Huang, S.J.6    Murphy, D.L.7
  • 16
    • 0019938340 scopus 로고
    • An indexed of the functional condition of rat sciatic nerve based on measurements made from walding tracks
    • de Medinaceli L., Freed W. J., Wyatt R. J. An indexed of the functional condition of rat sciatic nerve based on measurements made from walding tracks. Exp. Neurol. 77:1982;634-643.
    • (1982) Exp. Neurol. , vol.77 , pp. 634-643
    • De Medinaceli, L.1    Freed, W.J.2    Wyatt, R.J.3
  • 19
    • 0030029277 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis
    • Festoff B. W. Amyotrophic lateral sclerosis. Drugs. 51:1996;28-44.
    • (1996) Drugs , vol.51 , pp. 28-44
    • Festoff, B.W.1
  • 21
    • 0030831352 scopus 로고    scopus 로고
    • Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: Molecular mechanisms of neuronal death and protection
    • Ghadge G. D., Lee J. P., Bindokas V. P., Jordan J., Ma L., Miller R. J., Roos R. P. Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: Molecular mechanisms of neuronal death and protection. J. Neurosci. 17:1997;8756-8766.
    • (1997) J. Neurosci. , vol.17 , pp. 8756-8766
    • Ghadge, G.D.1    Lee, J.P.2    Bindokas, V.P.3    Jordan, J.4    Ma, L.5    Miller, R.J.6    Roos, R.P.7
  • 23
    • 0030927253 scopus 로고    scopus 로고
    • Transgenic animal models of familial amyotrophic lateral sclerosis
    • Gurney M. E. Transgenic animal models of familial amyotrophic lateral sclerosis. J. Neurol. 244:1997;S15-S20.
    • (1997) J. Neurol. , vol.244
    • Gurney, M.E.1
  • 24
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney M. E., Cutting F. B., Zhai P., Doble A., Taylor C. P., Andrus P. K., Hall E. D. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol. 39:1996;147-157.
    • (1996) Ann. Neurol. , vol.39 , pp. 147-157
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 26
    • 0026042995 scopus 로고
    • Cytopathology in amyotrophic lateral sclerosis
    • Hirano A. Cytopathology in amyotrophic lateral sclerosis. Adv. Neurol. 56:1991;91-101.
    • (1991) Adv. Neurol. , vol.56 , pp. 91-101
    • Hirano, A.1
  • 27
    • 0030862630 scopus 로고    scopus 로고
    • The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Hottinger A. F., Fine E. G., Gurney M. E., Zurn A. D., Aebischer P. The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. Eur. J. Neurosci. 9:1997;1548-1551.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1548-1551
    • Hottinger, A.F.1    Fine, E.G.2    Gurney, M.E.3    Zurn, A.D.4    Aebischer, P.5
  • 28
    • 0029658019 scopus 로고    scopus 로고
    • Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: An electromyographic study
    • Kennel P. F., Finiels F., Revah F., Mallet J. Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: An electromyographic study. Neuroreport. 8:1996;1427-1431.
    • (1996) Neuroreport , vol.8 , pp. 1427-1431
    • Kennel, P.F.1    Finiels, F.2    Revah, F.3    Mallet, J.4
  • 29
    • 0023359832 scopus 로고
    • Behavioral assessment of functional deficit in rats with contusive spinal cord injury
    • Kerasidis H., Wrathall J. R., Gale K. Behavioral assessment of functional deficit in rats with contusive spinal cord injury. J. Neurosci. Meth. 20:1987;167-189.
    • (1987) J. Neurosci. Meth. , vol.20 , pp. 167-189
    • Kerasidis, H.1    Wrathall, J.R.2    Gale, K.3
  • 30
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic V., Jackson-Lewis V., de Bilbao F., Dubois-Dauphin M., Przedborski S. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science. 277:1997;559-562.
    • (1997) Science , vol.277 , pp. 559-562
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 31
  • 32
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis
    • Lacomblez L., Bensimon G., Leigh P. N., Guillet P., Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet. 347:1996;1425-1431.
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5
  • 33
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell J. A., Akarasereenont P., Thiemermann C., Flower R. J., Vane J. R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA. 90:1994;11693-11697.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 34
  • 35
    • 0344867477 scopus 로고    scopus 로고
    • Immunocytochemical evidence of spinal cord lipid peroxidation, peroxynitrite formation, and astrocyte and microglial activation in the transgenic model of familial amyotrophic lateral sclerosis
    • Oostveen J. A., Gurney M. E., Hall E. D. Immunocytochemical evidence of spinal cord lipid peroxidation, peroxynitrite formation, and astrocyte and microglial activation in the transgenic model of familial amyotrophic lateral sclerosis. Soc. Neurosci. Abs. 23:1997;729.13.
    • (1997) Soc. Neurosci. Abs. , vol.23 , pp. 72913
    • Oostveen, J.A.1    Gurney, M.E.2    Hall, E.D.3
  • 36
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps M. E., Huntley G. W., Hof P. R., Morrison J. H., Gordon J. W. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA. 92:1995;689-693.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 38
    • 0030273704 scopus 로고    scopus 로고
    • Therapeutic horizons for amyotrophic lateral sclerosis
    • Rothstein J. D. Therapeutic horizons for amyotrophic lateral sclerosis. Curr. Opin. Neurobiol. 6:1996;679-687.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 679-687
    • Rothstein, J.D.1
  • 39
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein J. D., Martin L. J., Kuncl R. W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 236:1992;1464-1468.
    • (1992) N. Engl. J. Med. , vol.236 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 40
    • 0029077018 scopus 로고
    • Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuropathy in the mouse
    • Sagot Y., Tan S. A., Baetge E., Schmalbruch H., Kato A. C., Aebischer P. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuropathy in the mouse. Eur. J. Neurosci. 7:1995;1313-1322.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1313-1322
    • Sagot, Y.1    Tan, S.A.2    Baetge, E.3    Schmalbruch, H.4    Kato, A.C.5    Aebischer, P.6
  • 41
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy (see comments)
    • Sendtner M., Schmalbruch H., Stockli K. A., Carroll P., Kreutzberg G. W., Thoenen H. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy (see comments). Nature. 358:1992;502-504.
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 43
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W., Price D. L. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14:1995;1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.