-
1
-
-
0031916439
-
The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 561-573
-
-
Auer, K.1
Contessa, J.2
Brenz-Verca, S.3
Pirola, L.4
Rusconi, S.5
Cooper, G.6
Abo, A.7
Wymann, M.8
Davis, R.J.9
Birrer, M.10
Dent, P.11
-
9
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
11
-
-
0034278212
-
Expression of Bcl-2 inhibited Fas-mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells
-
(2000)
Cell Res.
, vol.10
, pp. 233-242
-
-
Chang, Y.C.1
Xu, Y.H.2
-
12
-
-
17444454260
-
Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS
-
(2000)
Radiat. Res.
, vol.154
, pp. 125-132
-
-
Cohen-Jonathan, E.1
Muschel, R.J.2
McKenna, G.W.3
Evans, S.M.4
Cerniglia, G.5
Mick, R.6
Kusewitt, D.7
Sebti, S.M.8
Hamilton, A.D.9
Oliff, A.10
Kohl, N.11
Gibbs, J.B.12
Bernhard, E.J.13
-
14
-
-
0032815618
-
Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 2493-2506
-
-
Dent, P.1
Reardon, D.B.2
Park, J.S.3
Bowers, G.4
Logsdon, C.5
Valerie, K.6
Schmidt-Ullrich, R.K.7
-
15
-
-
0034699353
-
Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis
-
(2000)
Oncogene
, vol.19
, pp. 4563-4573
-
-
Engels, I.H.1
Stepczynska, A.2
Stroh, C.3
Lauber, K.4
Berg, C.5
Schwenzer, R.6
Wajant, H.7
Janicke, R.U.8
Porter, A.G.9
Belka, C.10
Gregor, M.11
Schulze-Osthoff, K.12
Wesselborg, S.13
-
17
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 137-145
-
-
Faubion, W.A.1
Guicciardi, M.E.2
Miyoshi, H.3
Bronk, S.F.4
Roberts, P.J.5
Svingen, P.A.6
Kaufmann, S.H.7
Gores, G.J.8
-
18
-
-
0035870123
-
Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis
-
(2001)
Exp. Cel Res.
, vol.265
, pp. 145-151
-
-
Gao, C.F.1
Ren, S.2
Zhang, L.3
Nakajima, T.4
Ichinose, S.5
Hara, T.6
Koike, K.7
Tsuchida, N.8
-
20
-
-
0033756474
-
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
24
-
-
0034675853
-
MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly
-
(2000)
EMBO J.
, vol.19
, pp. 5418-5428
-
-
Holmstrom, T.H.1
Schmitz, I.2
Soderstrom, T.S.3
Poukkula, M.4
Johnson, V.L.5
Chow, S.C.6
Krammer, P.H.7
Eriksson, J.E.8
-
25
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
Rimoldi, D.11
French, L.E.12
Tschopp, J.13
-
26
-
-
0031785213
-
Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 844-856
-
-
Jarvis, W.D.1
Fornari, F.A.2
Tombes, R.M.3
Erukulla, R.K.4
Bittman, R.5
Schwartz, G.K.6
Dent, P.7
Grant, S.8
-
33
-
-
12644257582
-
Extrahepatic biliary obstruction impairs microvascular perfusion and increases leukocyte adhesion in rat liver
-
(1997)
Hepatology
, vol.26
, pp. 1085-1091
-
-
Koeppel, T.A.1
Trauner, M.2
Baas, J.C.3
Thies, J.C.4
Schlosser, S.F.5
Post, S.6
Gebhard, M.M.7
Herfarth, C.8
Boyer, J.L.9
Otto, G.10
-
34
-
-
0035854780
-
IL-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26605-26613
-
-
Kovalovich, K.1
Li, W.2
Deangelis, R.3
Greenbaum, L.E.4
Ciliberto, G.5
Taub, R.6
-
39
-
-
0034704939
-
Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway
-
(2000)
Oncogene
, vol.19
, pp. 1665-1675
-
-
Leu, C.M.1
Chang, C.2
Hu, C.3
-
44
-
-
0033378009
-
c-raf-1 depletion and tumor responses in patients treated with the c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A)
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3977-3982
-
-
O'Dwyer, P.J.1
Stevenson, J.P.2
Gallagher, M.3
Cassella, A.4
Vasilevskaya, I.5
Monia, B.P.6
Holmlund, J.7
Dorr, F.A.8
Yao, K.S.9
-
47
-
-
0034614442
-
Expression of human papilloma virus E7 protein causes apoptosis, and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6)
-
(2000)
J. Biol. Chem.
, vol.274
, pp. 18-28
-
-
Park, J.S.1
Boyer, S.2
Mitchell, K.3
Gilfor, D.4
Birrer, M.5
Darlington, G.6
El Deiry, W.7
Firestone, G.8
Munger, K.9
Band, V.10
Fisher, P.B.11
Dent, P.12
-
48
-
-
0034490479
-
A role for both ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 2915-2932
-
-
Park, J.S.1
Qiao, L.2
Gilfor, D.3
Yang, M.Y.4
Hylemon, P.5
Benz, C.6
Darlington, G.7
Firestone, G.8
Fisher, P.B.9
Dent, P.10
-
58
-
-
0033694859
-
BID-dependent, and BID-independent pathways for BAX insertion into mitochondria
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1101-1108
-
-
Ruffolo, S.C.1
Breckenridge, D.G.2
Nguyen, M.3
Goping, I.S.4
Gross, A.5
Korsmeyer, S.J.6
Li, H.7
Yuan, J.8
Shore, G.C.9
-
63
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
Todd, D.G.4
Valerie, K.5
Kavanagh, B.D.6
Contessa, J.N.7
Rorrer, W.K.8
Chen, P.B.9
-
65
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
(1999)
Nat. Med.
, vol.5
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
Van Becelaere, K.4
Wiland, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
Leopold, W.R.11
Saltiel, A.R.12
-
67
-
-
0031983188
-
Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat
-
(1998)
Gastroenterology
, vol.114
, pp. 164-174
-
-
Sokol, R.J.1
McKim J.M., Jr.2
Goff, M.C.3
Ruyle, S.Z.4
Devereaux, M.W.5
Han, D.6
Packer, L.7
Everson, G.8
-
70
-
-
0030810981
-
F.L.A.M.E-1, a novel F.A.D.D-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18542-18545
-
-
Srinivasula, S.M.1
Ahmad, M.2
Ottilie, S.3
Bullrich, F.4
Banks, S.5
Wang, Y.6
Fernandes-Alnemri, T.7
Croce, C.M.8
Litwack, G.9
Tomaselli, K.J.10
Armstrong, R.C.11
Alnemri, E.S.12
-
71
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of BID, not procaspases, is the most likely route
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredesen, D.8
Freeze, H.9
Abrahamson, M.10
Bromme, D.11
Krajewski, S.12
Reed, J.C.13
Yin, X.M.14
Turk, V.15
Salvesen, G.S.16
-
73
-
-
0035014692
-
The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits fas apoptosis upstream of bid in rodent hepatocytes
-
(2001)
Gastroenterology
, vol.120
, pp. 1810-1817
-
-
Takikawa, Y.1
Miyoshi, H.2
Rust, C.3
Roberts, P.4
Siegel, R.5
Mandal, P.K.6
Millikan, R.E.7
Gores, G.J.8
-
74
-
-
0033858091
-
Mechanism for the transit-induced increase in colonic deoxycholic acid formation in cholesterol cholelithiasis
-
(2000)
Gastroenterology
, vol.119
, pp. 806-815
-
-
Thomas, L.A.1
Veysey, M.J.2
Bathgate, T.3
King, A.4
French, G.5
Smeeton, N.C.6
Murphy, G.M.7
Dowling, R.H.8
-
75
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
77
-
-
0030348110
-
Protein tyrosine phosphatases and the control of cellular signaling responses
-
(1996)
Adv. Pharmacol.
, vol.36
, pp. 91-119
-
-
Tonks, N.K.1
-
82
-
-
17344370605
-
Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes
-
(1998)
Hepatology
, vol.27
, pp. 1324-1331
-
-
Webster, C.R.1
Anwer, M.S.2
-
85
-
-
0033944665
-
Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes
-
(2000)
J. Mol. Med.
, vol.78
, pp. 203-211
-
-
Yin, X.M.1
-
86
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
Zhao, Y.4
Zinkel, S.5
Klocke, B.6
Roth, K.A.7
Korsmeyer, S.J.8
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