Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: Evidence for a postmitochondrial processing of caspase-8

Toxicological Sciences

Volumn 58, Issue 1, 2000, Pages 109-117

  Bajt, Mary Lynn ^a   Lawson, Judy A ^b   Vonderfecht, Steven L ^b   Gujral, Jaspreet S ^a   Jaeschke, Hartmut ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b PFIZER INC   (United States)

Author keywords

Caspase cascade; Caspase 8 inhibitor; Cytochrome c; Fas induced liver failure; IETD CHO; Liver cell apoptosis; Mitochondria

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CYTOCHROME C; FAS LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ENZYME ACTIVITY; LIVER CELL; LIVER FAILURE; LIVER TOXICITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN;

ANIMALIA;

EID: 0033735804     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/58.1.109     Document Type: Article

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