Pro-caspase-8 Is Predominantly Localized in Mitochondria and Released into Cytoplasm upon Apoptotic Stimulation

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 8079-8086

  Qin, Zheng Hong ^a   Wang, Yumei ^a   Kikly, Kristine K ^b   Sapp, Ellen ^a   Kegel, Kimberly B ^a   Aronin, Neil ^c   DiFiglia, Marian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CLONING; ELECTRON MICROSCOPY; FLUORESCENCE; IMMUNOLOGY; TUMORS;

APOPTOTIC STIMULATION; FIBROBLASTS; MITOCHONDRIA;

BIOCHEMISTRY;

ATRACTYLOSIDE; CYCLOSPORIN A; CYTOCHROME C; ENZYME PRECURSOR; PROCASPASE 8; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADENINE NUCLEOTIDE TRANSLOCASE; CARRIER PROTEIN; CASP8 PROTEIN, HUMAN; CASP8 PROTEIN, MOUSE; CASP9 PROTEIN, HUMAN; CASP9 PROTEIN, MOUSE; CASPASE; CASPASE 8; CASPASE 9; CYCLOSPORIN; ION CHANNEL; MEMBRANE PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; ENZYME ACTIVATION; ENZYME LOCALIZATION; FIBROBLAST; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL CULTURE; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY;

ANIMALIA;

APOPTOSIS; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; CYCLOSPORINE; CYTOPLASM; ENZYME PRECURSORS; HUMANS; IMMUNOHISTOCHEMISTRY; ION CHANNELS; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035896592     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007028200     Document Type: Article

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