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Volumn 10, Issue 4, 2000, Pages 649-668

Neuroimmunology of multiple sclerosis and experimental allergic encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; MYELIN; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN;

EID: 0034447657     PISSN: 10525149     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (6)

References (215)
  • 2
    • 0028828168 scopus 로고
    • The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis inthe Lewis rat
    • (1995) J Neuroimmunol , vol.63 , pp. 17
    • Adelman, M.1    Wood, J.2    Benzel, I.3
  • 4
    • 0027256807 scopus 로고
    • Identification of a major encephalitogenic epitope of proteolipid protein (residues 56-70) for the induction of experimental allergic encephalomyelitis in Biozzi AB/H and nonobese diabetic mice
    • (1993) J Immunol , vol.150 , pp. 5666
    • Amor, S.1    Baker, D.2    Groome, N.3
  • 5
    • 0028006884 scopus 로고
    • Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice
    • (1994) J Immunol , vol.153 , pp. 4349
    • Amor, S.1    Groome, N.2    Linington, C.3
  • 6
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • (1989) Cell Immunol , vol.124 , pp. 132
    • Ando, D.G.1    Clayton, J.2    Kono, D.3
  • 13
    • 0033168749 scopus 로고    scopus 로고
    • FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: Evidence for the existence of an immunological brain barrier
    • (1999) Glia , vol.27 , pp. 62-74
    • Bechmann, I.1    Mor, G.2    Nilsen, J.3
  • 15
    • 0019986548 scopus 로고
    • Experimental autoimmune encephalomyelitis (EAE) mediated by T cell line: Process of selection of lines and characterization of the T cells
    • (1982) J Immunol , vol.129 , pp. 303
    • Ben Nun, A.1    Cohen, I.R.2
  • 17
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of myelin basic protein peptide (83-99) in multiple sclerosis - Results of a phase II clinical trial with an altered peptide ligand
    • (2000) Nat Med , vol.6 , pp. 1167-1175
    • Bielekova, B.1    Goodwin, B.2    Richert, N.3
  • 22
    • 0027454052 scopus 로고
    • Induction of relapsing paralysis in experimental allergic encephalomyelitis by bacterial superantigen
    • (1993) Nature , vol.365 , pp. 642
    • Brocke, S.1    Gaur, A.2    Piercy, C.3
  • 23
    • 0030069797 scopus 로고    scopus 로고
    • Dynamics of autoimmune T cell infiltration: Reversal of paralysis and disappearance of inflammation following treatment of experimental encephalomyelitis with a myelin basic protein peptide analog
    • (1996) Nature , vol.379 , pp. 343
    • Brocke, S.1    Gijbels, K.2    Allegretta, M.3
  • 24
    • 0033960042 scopus 로고    scopus 로고
    • Combination therapy with glatiramer acetate (copolymer-1) and a type I interferon (IFN-alpha) does not improve experimental autoimmune encephalomyelitis
    • (2000) Ann Neurol , vol.47 , pp. 127
    • Brod, S.A.1    Lindsey, J.W.2    Wolinsky, J.S.3
  • 36
    • 0032707209 scopus 로고    scopus 로고
    • Intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: Present status and practical therapeutic guidelines
    • (1999) Muscle Nerve , vol.22 , pp. 1479
    • Dalakas, M.C.1
  • 46
    • 0030918326 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis
    • (1997) J Exp Med , vol.185 , pp. 2177
    • Frei, K.1    Eugster, H.P.2    Bopst, M.3
  • 51
    • 0022375427 scopus 로고
    • Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
    • (1985) Science , vol.230 , pp. 1043
    • Fujinami, R.S.1    Oldstone, M.B.A.2
  • 52
    • 0030973661 scopus 로고    scopus 로고
    • Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms
    • (1997) J Neuroimmunol , vol.74 , pp. 149
    • Gaur, A.1    Boehme, S.A.2    Chalmers, D.3
  • 57
    • 0033976207 scopus 로고    scopus 로고
    • Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: Epitope spreading versus clonal persistence
    • (2000) Brain , vol.123 , pp. 508
    • Goebels, N.1    Hofstetter, H.2    Schmidt, S.3
  • 58
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • (1993) Cell , vol.72 , pp. 551
    • Goverman, J.1    Woods, A.2    Larson, L.3
  • 62
    • 0033546665 scopus 로고    scopus 로고
    • TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study
    • (1999) Neurology , vol.53 , pp. 457
  • 69
    • 0023949553 scopus 로고
    • Perivascular microglia cells of the central nervous system are bone marrow derived and present antigen in vivo
    • (1988) Science , vol.239 , pp. 290
    • Hickey, W.F.1    Kimura, H.2
  • 71
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents of the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 72
    • 0034650603 scopus 로고    scopus 로고
    • Myelin-associated oligodendrocytic basic protein: Identification of an encephalitogenic epitope and association with multiple sclerosis
    • (2000) J Immunol , vol.164 , pp. 1103
    • Holz, A.1    Bielekova, B.2    Martin, R.3
  • 78
    • 0002481864 scopus 로고
    • A study of the cristalline albumin, gamma globulin and total protein in the cerebrospinal fluid of one hundred cases of multiple sclerosis and in other diseases
    • (1950) Am J Med Sci , vol.219 , pp. 55-64
    • Kabat, E.A.1    Freedman, D.A.2    Murray, J.P.3
  • 79
    • 0028148199 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon γ and tumor necrosis factor α production
    • (1994) J Exp Med , vol.180 , pp. 2227
    • Karin, N.1    Mitchell, D.J.2    Brocke, S.3
  • 81
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • (1995) J Immunol , vol.155 , pp. 5003
    • Karpus, W.1    Lukacs, N.W.2    McRae, B.L.3
  • 85
    • 0028965522 scopus 로고
    • Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: Preliminary analysis of MOG T cell epitopes
    • (1995) Eur J Immunol , vol.25 , pp. 985
    • Kerlero de Rosbo, N.1    Mendel, I.2    Ben-Nun, A.3
  • 87
    • 0033103608 scopus 로고    scopus 로고
    • Activated human T cells, B cells, and monocytes produced brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation?
    • (1999) J Exp Med , vol.189 , pp. 865
    • Kerschensteiner, M.1    Gallmeier, E.2    Behrens, L.3
  • 89
    • 0027990803 scopus 로고
    • Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100b molecule, a calcium binding protein of astroglia
    • (1994) J Exp Med , vol.180 , pp. 817
    • Kojima, K.1    Berger, T.2    Lassmann, H.3
  • 90
    • 0034678450 scopus 로고    scopus 로고
    • Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
    • (2000) J Exp Med , vol.191 , pp. 1395
    • Krogsgaard, M.1    Wucherpfennig, K.W.2    Cannella, B.3
  • 94
    • 0030739650 scopus 로고    scopus 로고
    • Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immuno-deficient hosts rather than protect them from the disease
    • (1997) J Exp Med , vol.186 , Issue.2 , pp. 307
    • Lafaille, J.J.1    Keere, F.V.2    Hsu, A.L.3
  • 98
    • 0032753320 scopus 로고    scopus 로고
    • Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein
    • (1999) Brain , vol.122 , pp. 2089
    • Lindert, R.B.1    Haase, C.G.2    Brehm, U.3
  • 99
  • 100
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
    • (1988) Am J Pathol , vol.30 , pp. 443
    • Linington, C.1    Bradl, M.2    Lassmann, H.3
  • 105
    • 0031731797 scopus 로고    scopus 로고
    • Encephalitogenicity of myelin-associated oligodendrocyte basic protein and 2′,3′-cyclic nucleotide 3′-phosphodi-esterase for Balb/c and SJL mice
    • (1998) Immunology , vol.95 , pp. 383
    • Maatta, J.A.1    Kaldman, M.S.2    Sakoda, S.3
  • 109
    • 0025966510 scopus 로고
    • A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis
    • (1991) J Exp Med , vol.173 , Issue.1 , pp. 19-24
    • Martin, R.1    Howell, M.D.2    Jaraquemada, D.3
  • 110
    • 0024997357 scopus 로고
    • Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals
    • (1990) J Immunol , vol.145 , pp. 540
    • Martin, R.1    Jaraquemada, D.2    Flerlage, M.3
  • 116
    • 0026628844 scopus 로고
    • Immune regulation by brain cells in the central nervous systems: Microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions
    • (1992) Immunology , vol.76 , pp. 209
    • Matsumoto, Y.1    Ohmori, K.2    Fujiwara, M.3
  • 119
    • 0001086744 scopus 로고    scopus 로고
    • Comparative analysis of the outcome of two phase III studies of interferon beta-1b
    • (2000) Neurology , vol.54 , pp. 2352
    • McFarland, H.F.1
  • 123
    • 0030749517 scopus 로고
    • Immunodominance of a low-affinity MHC binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire
    • (1989) J Clin Invest , vol.100 , pp. 339
    • Muraro, P.A.1    Vergelli, M.2    Kalbus, M.3
  • 129
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cells subsets
    • (1998) Immunity , vol.8 , pp. 275
    • O'Garra, A.1
  • 132
  • 134
    • 0023099872 scopus 로고
    • Chronic-progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemia-like cells
    • (1987) Ann Neurol , vol.21 , pp. 117
    • Osame, M.1    Matsumoto, M.2    Usuku, K.3
  • 136
    • 0001149859 scopus 로고
    • Transfer of allergic encephalomyelitis in rats by means of lymph node cells
    • (1960) J Exp Med , vol.111 , pp. 119
    • Paterson, P.Y.1
  • 140
    • 0025155486 scopus 로고
    • Myelin autoreactivity in multiple sclerosis: Recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple sclerosis patients and healthy donors
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7968
    • Pette, M.1    Fujita, K.2    Wilkinson, D.3
  • 141
    • 0032981341 scopus 로고    scopus 로고
    • The immuno-modulatory profile of phosphodiesterase type 4-specific inhibition of human autoreactive T cell clones: Basis for the treatment of T helper 1 lymphocyte-mediated autoimmune diseases?
    • (1999) J Neuroimmunol , vol.98 , pp. 147
    • Pette, M.1    Muraro, P.A.2    Pette, D.F.3
  • 142
    • 0019465748 scopus 로고
    • Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vivo activation of lymph node cells by myelin basic protein: Requirement for Lyt-1 + 2-T lymphocytes
    • (1981) J Immunol , vol.127 , pp. 1420
    • Pettinelli, C.B.1    McFarlin, D.E.2
  • 145
    • 0033021055 scopus 로고
    • Mechanisms of inflammation in MS tissue: Adhesion molecules and chemokines
    • (1989) J Neuroimmunol , vol.98 , pp. 57-68
    • Ransohoff, R.1
  • 147
    • 0032723691 scopus 로고    scopus 로고
    • Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: A comparative study
    • (1999) Brain , vol.122 , pp. 2047
    • Reindl, M.1    Linington, C.2    Brehm, U.3
  • 150
    • 0028985320 scopus 로고
    • Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • (1995) Ann Neurol , vol.37 , pp. 82
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3
  • 163
    • 0000337323 scopus 로고    scopus 로고
    • Induction of multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein
    • (1998) Autoimmunity , vol.28 , pp. 109
    • Slavin, A.1    Ewing, C.2    Liu, J.3
  • 164
    • 17444453701 scopus 로고    scopus 로고
    • Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA
    • (1997) Nature Med , vol.3 , pp. 1394
    • Soldan, S.S.1    Berti, R.2    Salem, N.3
  • 167
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 171
    • 0022650254 scopus 로고
    • Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes
    • (1986) Nature , vol.320 , pp. 70
    • Sun, D.1    Wekerle, H.2
  • 173
    • 0032080658 scopus 로고    scopus 로고
    • Presentation of proteolipid proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes
    • (1998) J Immunol , vol.160 , pp. 4271
    • Tan, L.1    Gordon, K.B.2    Mueller, J.P.3
  • 180
    • 0023902649 scopus 로고
    • Myelin proteolipid protein-induced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice
    • (1988) J Immunol , vol.140 , pp. 1868
    • Tuohy, V.K.1    Sobel, R.A.2    Lees, M.B.3
  • 181
    • 0031726374 scopus 로고    scopus 로고
    • The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis
    • (1998) Immunol Rev , vol.164 , pp. 93-100
    • Tuohy, V.K.1    Yu, M.2    Yin, L.3
  • 182
    • 0027389119 scopus 로고
    • Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients
    • (1993) J Clin Invest , vol.91 , pp. 616
    • Valli, A.1    Sette, A.2    Kappos, L.3
  • 187
    • 0031569454 scopus 로고    scopus 로고
    • Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells
    • (1997) J Immunol , vol.158 , pp. 3746
    • Vergelli, M.1    Hemmer, B.2    Kalbus, M.3
  • 189
    • 10244247768 scopus 로고    scopus 로고
    • Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99)
    • (1996) Eur J Immunol , vol.26 , pp. 2624
    • Vergelli, M.1    Hemmer, B.2    Utz, U.3
  • 195
    • 0028053052 scopus 로고
    • Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis
    • (1994) Ann Neurol , vol.35 , pp. 89-97
    • Washington, R.1    Burton, J.2    Todd, R.F.3
  • 198
    • 0033103270 scopus 로고    scopus 로고
    • Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11, and transforming growth factor-β1 (TGF-β1) downregulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia
    • (1999) J Neuroimmunol , vol.95 , pp. 8-18
    • Wei, R.T.1    Jonakait, G.M.2
  • 206
    • 0030961031 scopus 로고    scopus 로고
    • Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2 restricted T cell clones from multiple sclerosis patients: Identity of key contact residues in the B-cell and T-cell epitopes
    • (1997) J Clin Invest , vol.100 , pp. 1114
    • Wucherpfennig, K.W.1    Catz, I.2    Hausmann, S.3
  • 208
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 211
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • (1994) J Exp Med , vol.179 , pp. 973
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3


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