Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes

Journal of Clinical Investigation

Volumn 100, Issue 5, 1997, Pages 1114-1122

  Wucherpfennig, Kai W ^a,d   Catz, Ingrid ^b   Hausmann, Stefan ^a   Strominger, Jack L ^a   Steinman, Lawrence ^c   Warren, Kenneth G ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c STANFORD UNIVERSITY   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Antigen recognition; Autoimmunity; B cells; Bacterial peptides; Viral peptides

Indexed keywords

AUTOANTIBODY; HLA DR2 ANTIGEN; MYELIN BASIC PROTEIN;

ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; HLA SYSTEM; HUMAN; LYMPHOCYTE CLONE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0030961031     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119622     Document Type: Article

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