Chemokines in immune-mediated inflammation of the central nervous system

Cytokine and Growth Factor Reviews

Volumn 7, Issue 1, 1996, Pages 35-46

  Ransohoff, Richard M ^a,b   Glabinski, Andrzej ^a,c   Tani, Marie ^a,b  

^a Research Institute   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Central nervous system; Chemokines; Encephalomyelitis; Inflammation; Multiple sclerosis

Indexed keywords

ANTIBODY; CHEMOKINE; CHEMOKINE RECEPTOR; COMPLEMENTARY DNA; CYTOKINE RECEPTOR; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL; ANIMAL CELL; ANIMAL MODEL; BLOOD; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; ENCEPHALOMYELITIS; HUMAN; IMMUNOLOGY; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE; MULTIPLE SCLEROSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OLIGODENDROGLIA; PHYSIOLOGY; RECURRENT DISEASE; SHORT SURVEY; TRANSGENIC MOUSE;

EID: 0030183050     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/1359-6101(96)00003-2     Document Type: Short Survey

References (85)

1. 1. Fabry Z, Raine C, Hart M. Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. Immunol Today 1994, 15, 218-224.
2. 2. Tani M, Ransohoff RM. Do chemokines mediate inflammatory cell invasion of the central nervous system parenchyma? Brain Pathol 1994, 4, 135-143.
3. 3. Leibowitz S, Hughes RAC. Immunology of the Nervous System, London, Edward Arnold, 1983.
4. 4. Lassmann H, Zimprich F, Rossler K, Vass K. Inflammation in the nervous system. Basic mechanisms and immunological concepts. Rev Neurol 1991, 147, 763-781.
5. 5. Hickey WF, Kimura H. Perivascular microglial cells of the CNS are bone-marrow derived and present antigen in vivo. Science 1988, 239, 290-292.
6. 6. Hickey WF, Hsu BL, Kimura H. T-lymphocyte entry into the central nervous system. J Neurosci Res 1991, 28, 254-260.
7. 7. Hickey WF. Migration of hematogenous cells through the blood-brain barrier and the initiation of CNS inflammation. Brain Pathol 1991, 1, 97-105.
8. 8. Hinrichs DJ, Wegmann KW, Dietsch GN. Transfer of EAE to bone marrow chimeras. Endothelial cells are not a restricting element. J Exp Med 1987, 166, 1906-1911.
9. 9. Miller S, Karpus W. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol Today 1994, 15, 356.
10. 10. Tuohy V, Fritz R, Ben-Nun A. Self-determinants in autoimmune demyelinating disease: changes in T-cell response specificity. Curr Opin Immunol 1994, 6, 887-891.
11. 11. Ben-Nun A, Wekerle H, Cohen IR. The rapid isolation of a clonable antigen-specific T-lymphocyte lines capable of mediating EAE. Eur J Immunol 1981, 11, 195-199.
12. 12. Lassmann H. Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis. Berlin, Springer.
13. 13. Raine CS. Analysis of autoimmune demyelination: its impact upon multiple sclerosis. Lab Invest 1984, 50, 608-635.
14. 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelilis. Lab Invest 1990, 63, 162-170.
15. 15. Cross AH, O'Mara T, Raine CS. Chronologic localization of myelin-reactive cells in the lesions of relapsing EAE: implications for the study of multiple sclerosis. Neurology 1993, 43, 1028-1033.
16. 16. Mackay CR. Migration pathways and immunologic memory among T lymphocytes. Semin Immunol 1992, 4, 51-58.
17. 17. Cannella B, Cross AH, Raine CS. Up-regulation and co-expression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system. J Exp Med 1990, 172, 1521 -1524.
18. 18. Cannella B, Cross AH, Raine CS. Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis. J Neuroimmunol 1993, 46, 43-56.
19. 19. Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha-4beta 1 integrin. Nature 1992, 356, 63-66.
20. 20. Butcher E. Leukocyte endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 1991, 67, 1033-1036.
21. 21. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994, 76, 301-314.
22. 22. Muller W, Weigl S, Dene X, Phillips D. PECAM-I is required for transendothelial migration of leukocytes. J Exp Med 1993, 178, 449-460.
23. 23. Oppenheim JJ, Zachariae C, Mukaida N, Matsushima K. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Ann Rev Immunol 1991, 9, 617-648.
24. 24. Wolpe S, Cerami A. Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines. FASEB J 1989, 3, 2565-2573.
25. 25. Miller MD, Krangel MS. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol 1992, 12, 17-46.
26. 26. Detmers PA, Lo SK, Olsen-Egbert E, Walz A, Baggiolini M, Colin ZA. Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of leukocyte adhesion receptor CD1 1b/CD18 on human neutrophils. J Exp Med 1990, 171, 1555-1562.
27. 27. Baggiolini M, Clark-Lewis I. Interleukin-8, a chemotactic and inflammatory cytokine. FEBS Lett 1992, 307, 97-101.
28. 28. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 1994, 55, 97-179.
29. 29. Baggiolini M, Dahinden CA. CC Chemokines in allergic inflammation. Immunol Today 1994, 15, 127-133.
30. 30. Gomez-Chiari M, Ortiz A, Seron D, Gonzalez E, Egido J. The intercrine superfamily and renal disease. Kidney Int 1993, 43 (Suppl 39), S81-S85.
31. 31. Gray P. The role of chemokines and their receptors in leukocyte activation. In Gallagher K. ed. Chemotactic Cytokines: Targets for Therapeutic Development. Washington, DC. 1994, 118-126.
32. 32. Kunkel SL, Standiford T, Kasahara K, Stricter RM. Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res 1991, 17, 17-23.
33. 33. Lindley I, Westwick J, Kunkel S, Nomenclature announcement: the chemokines. Immunol Today 1993, 14, 24.
34. 34. Yoshimura T, Robinson EA. Tanaka S, Appella E, Kuratsu J, Leonard EJ. Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med 1989, 169, 1449-1459.
35. 35. Furie M, Randolph G. Chemokines and tissue injury. Am J Pathol 1995, 146, 1287-1301.
36. 36. Tanaka Y, Adams DH, Hubscher S, Hirano H, Siebenlist U, Shaw S. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1 beta. Nature 1993, 361, 79-82.
37. 37. Carr MW, Roth SJ, Luther E, Rose SS, Springer TA. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci USA 1994, 91, 3652-3656.
38. 38. Rollins B, Stier P, Ernst T, Wong G. The human homolog of the JE gene encodes a monocyte secretory protein. Mol Cell Biol 1989, 9, 4687-4689.
39. 39. Rollins B, Walz A, Baggiolini M. Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 1991, 78, 1112-1116.
40. 40. Yoshimura T, Robinson EA. Tanaka S, Appella E, Leonard EJ. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J Immunol 1989, 142, 1956-1962.
41. 41. Schall TJ, Bacon K, Toy KJ, Goeddel DV. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 1990, 347, 669-671.
42. 42. Ming Wang J, McVicar DW, Oppenheim JJ, Kelvin DJ. Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines. J Exp Med 1993, 177, 699-705.
43. 43. Taub DD, Conlon K, Lloyd AR, Oppenheim JJ, Kelvin DJ. Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1 alpha and MIP-1 beta. Science 1993, 260, 355-358.
44. 44. Yoshimura T, Matsushima K, Tanaka S, Robinson EA, Appella E, Oppenheim JJ, Leonard EJ. Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defence cytokines. Proc Natl Acad Sci USA 1987, 84, 9233-9237.
45. 45. Larsen CG, Anderson AO, Appella E, Oppenheim JJ, Matsushima K. The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes. Science 1989, 243, 1464-1466.
46. 46. Taub DD, Lloyd AR, Conlon K, Ming Wang J, Ortaldo JR, Harada A, Matsushima K, Kelvin DJ, Oppenheim JJ. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 1993, 177, 1809-1814.
47. 47. Luster AD, Leder P. IP-10, a CXC chemokine, elicits a potent thymus-dependent antitumor response in vivo. J Exp Med 1993, 178, 1057-1065.
48. 48. Cook D, Beck M, Coffman T, Kirby S, Sheridan J, Pragnell I, Smithies O. Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science 1995, 269, 1583-1585.
49. 49. Murphy P. The molecular biology of leukocyte chemoattractant receptors. Ann Rev Immunol 1994, 12, 593-633.
50. 50. Kelvin D, Michiel D, Johnston J, Lloyd A, Sprenger H, Oppenhein J, Wang J-M. Chemokines and serpentines: the molecular biology of chemokine receptors. J Leukocyte Biol 1993, 54, 604-612.
51. 51. Horuk R. Molecular properties of the chemokine receptor family. Trends Pharmacol Sci 1994, 15, 159-165.
52. 52. Horuk R. The interleukin-8-receptor family: from chemokines to malaria. Immunol Today 1994, 15, 169-174.
53. 53. Ben-Baruch A, Michiel DF, Oppenheim JJ. Signals and receptors involved in recruitment of inflammatory cells. J Biol Chem 1995, 270, 11703-11706.
54. 54. Wu D, La Rosa GJ, Simon MI. G-Protein-coupled signal transduction pathways for interleukin-8. Science 1993, 261, 101-103.
55. 55. Horuk E, Chitnis CE, Darbonne WC, Colby TJ, Rybicki A, Hadley TJ, Miller H. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 1993, 261, 1182-1184.
56. 56. Chaudhuri A, Zbrzezna V, Polyakova J, Pogo A. Hesselgesser J, Horuk R. Expression of the Duffy antigen in K562 cells: evidence that it is the human chemokine erythrocyte receptor. J Biol Chew 1994, 269, 7835-7838.
57. 57. Chaudhuri A, Polyakova J, Zbrzezna V, Williams K, Gulati S, Pogo A. Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite. Proc Natl Acad Sci USA 1993, 90, 10793-10797.
58. 58. Neote K, Darbonne W, Ogez J, Horuk R, Schall T. Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells. J Biol Chem 1993, 268, 12247-12249.
59. 59. Horuk R, Colby T, Darbonne W, Schall T, Neote K. The human erythrocyte inflammatory peptide (chemokine) receptor. Biochemical characterization, solubilization, and development of a binding assay for the soluble receptor. Biochemistry 1993, 32, 5733-5738.
60. 60. Ahuja S, Murphy P. Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri. J Biol Chem 1993, 268, 20691-20694.
61. 61. Ahuja S, Gao J-L, Murphy P. Chemokine receptors and molecular mimickry. Immunol Today 1994, 15, 281-287.
62. 62. Murphy PM. Molecular piracy of chemokine receptors by herpesviruses. Infect Agents Dis 1994, 3, 137-154.
63. 63. Bo L, Peterson JW, Mork S, Huffman PA, Gallatin WM, Ransohoff RM, Trapp BD. Distribution of immunoglobulin superfamily members ICAM-1, -2, -3 and the β2 integrin LFA-1 in multiple sclerosis lesions (submitted).
64. 64. Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neural 1995, 37, 424-435.
65. 65. Bo L, Mork S, Kong P, Nyland H, Pardo C, Trapp B. Detection of MHC class II-antigens on macrophages and microglia, but on astrocytes and endothelial in active MS. J Neuroimmunol 1994, 51, 135-146.
66. 66. Hulkower K, Brosnan CF, Aquino DA, Cammer W, Kulshrestha S, Guida MP, Rapoport DA, Berman JW. Expression of CSF-1. c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis. J Immunol 1993, 150, 2525-2533.
67. 67. Kuchroo VK, Martin CA, Greer JM, Ju S-T, Sobel RA, Dorf ME. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J Immunol 1993, 151, 4371-4382.
68. 68. Ransohoff RM, Hamilton TA, Tani M, Stoler MH, Shick HE, Major JA, Estes ML, Thomas DM, Tuohy VK. Astrocyte expression of mRNA encoding cytokines IP-10 and JE MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 1993, 7, 592-600.
69. 69. Godiska R, Chantry D, Dietsch G, Gray P. Chemokine expression in murine experimental autoimmune encephalomyelitis. J Neuroimmunol 1995, 58, 167-176.
70. 70. Glabinski A, Tani M, Tuohy VK, Tuthill RJ, Ransohoff RM. Central nervous system chemokine mRNA accumulation follows leukocyte entry at the onset of murine acute experimental autoimmune encephalomyelitis. Brain Behav Immun 1995, 9, 315-330.
71. 71. Yu M, Nishiyama A, Trapp B, Tuohy V. Interteron-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis. J Neuroimmunol (in press).
72. 72. Yu M, Johnson J, Tuohy V. A predictable sequential pattern of determinant spreading invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease. J Exp Med (in press).
73. 73. Hayashi M, Luo Y, Laning J, Strieter R, Dorf, M. Production and function of monocyte chemoattractant protein-1 and other beta-chemokines in murine glial cells. J Neuroimmunol 1995, 60, 143-150.
74. 74. Godiska R, Chantry D, Dietsch G, Gray P. Chemokine expression in murine experimental autoimmune encephalomyelitis. J Leukocyte Biol 1994, Suppl 17 (Abstract).
75. 75. Miyagishi R, Kikuchi S, Fukazawa T, Tashiro K. Macrophage inflammatory protein-1x in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases. J Neurol Sci 1995, 129, 223-227.
76. 76. Karpus WJ, Lukacs NW, McRae BL, Strieter RM, Kunkel SL, Miller SD. An important role for the chemokine macrophage inflammatory protein-1x in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol 1995, 155, 5003-5010.
77. 77. Andersson PB, Perry VH, Gordon S. Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system. J Exp Med 1992, 176, 255-259.
78. 78. Friedrich V, Holstein G, Li X, Gow A, Kelley K, Lazzarini R. Intracellular distribution of transgenic bacterial betagalactosidase in central nervous system neurons and glia. J Neurosci Res 1993, 36, 88.
79. 79. Fuentes M, Durham S, Swerdel M, Lewin A, Barton D, Megill J, Bravo R, Lira S. Controlled recruitment of monocytes macrophages to specific organs via transgenic expression of MCP-1. J Immunol 1995, 155, 5769-5776.
80. 80. Tani M, Fuentes ME, Peterson JW, Trapp BD, Durham SK, Loy JK, Bravo R, Ransohoff RM, Lira SA. Neutrophil infiltration, glial reaction and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest (in press).
81. 81. Lira SA, Zalamea P, Heinrich JN, Fuentes ME, Carrasco D, Eewin AC, Barton DS, Durham S, Bravo R. Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. J Exp Med 1994, 180, 2039-2048.
82. 82. Power C, Kong P-A, Trapp B. MHC Class I expression in oligodendrocytes induces hypomyelination in transgenic mice. J Neurosci Res (in press).
83. 83. Kunkel S, Strieter R, Lindley I, Westwick J. Chemokines: new ligands, receptors and activities. Immunol Today 1995, 12, 559-561.
84. 84. Horuk R, Martin A, Wang Z, Hadley T, Hesslegesser J, Lu Z, Peiper S. Chemokine receptors are expressed in the central nervous system. Ninth International Congress of Immunology. San Francisco, 1995, Abstract 632.
85. 85. Bolin L, Murray R, Schall T, Bacon K. RANTES induces differentiation and migration of primary sensory neurons. Ninth International Congress of Immunology. San Francisco, 1995, Abstract 640.