Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients

Annals of Neurology

Volumn 47, Issue 3, 2000, Pages 306-313

  Soldan, Samantha S ^a,b   Leist, Thomas P ^a   Juhng, K Newton ^a   McFarland, Henry F ^a   Jacobson, Steven ^a,c  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b GEORGE WASHINGTON UNIVERSITY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; DEMYELINATION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; LYMPHOCYTE PROLIFERATION; MULTIPLE SCLEROSIS; NEUROTROPISM; PATHOGENESIS; PRIORITY JOURNAL;

ADULT; CELL LINE; HERPESVIRUS 6, HUMAN; HUMANS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MULTIPLE SCLEROSIS;

EID: 0034008835     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200003)47:3<306::AID-ANA5>3.0.CO;2-A     Document Type: Article

References (47)

1. Gessain A, Barin F, Vernant JC, et al. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet 1985;2:407-410
2. Astrom KE, Mancall EL, Richardson EP Jr. Progressive multifocal leukoencephalopathy. Brain 1958;81:93-111
3. Horvath CJ, Simon MA, Bergsagel DJ, et al. Simian virus 40 (SV-40)-induced disease in rhesus monkeys with simian acquired immunodeficiency syndrome. Am J Pathol 1992;140: 1431-1440
4. Lecchi A. Viruses and demyelination in the central nervous system. Ital J Neurol Sci Suppl 1992;2:23-26
5. Zubriggen A, Yamawaki M, Vandevelde M. Restricted canine distemper virus infection of oligodendrocytes. Lab Invest 1993; 68:277-284
6. Lipton SA. Neuropathogenesis of acquired immunodeficiency syndrome. Curr Opin Neurol 1997;10:247-253
7. Lipton HL. Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination. Infect Immun 1975;11:1147-1155
8. Challoner PB, Smith KT, Parker JD, et al. Plaque-associated expression of human herpes virus 6 in multiple sclerosis. Proc Natl Acad Sci USA 1995;92:7440-7444
9. Soldan SS, Berti R, Salem N, et al. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nat Med 1997;3:1994-1997
10. Ablashi DV, Lapps W, Kaplan M, et al. Human herpesvirus-6 (HHV-6) infection in multiple sclerosis: a preliminary report. Mult Scler 1998;4:490-496
11. Ablashi DV, Lapps W, Richert J. Immuno-virological investigations of HHV-6 in the pathogenesis of multiple sclerosis (MS). Presented at the Second International Conference of Human Herpesvirus 6, 7, and 8 held in Pisa, Italy, May 8-11, 1997.
12. Wilborn F, Schmidt CA, Brinkmann V, et al. A potential role for human herpesvirus type 6 in nervous system disease. J Neuroimmunol 1994;49:213-214
13. Martin C, Enbom M, Soderstrom M, et al. Absence of seven human herpesviruses including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis. Acta Neurol Scand 1997;95:280-283
14. Merelli E, Bedin R, Sola P, et al. Human herpes virus 6 and human herpes virus DNA sequences in brains of multiple sclerosis patients, nromal adults and children. J Neurol 1997;244: 450-454
15. Liedtke W, Malessa R, Faustmann PM, Eis-Hubinger A. Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. J Neurovirol 1995;1:253-258
16. Fillet AM, Lozeron P, Agut H, et al. HHV-6 and multiple sclerosis. Nat Med 1998;4:537 (Letter)
17. Jacobson S, Soldan SS, Berti R. HHV-6 and multiple sclerosis. Nat Med 1998;4:538 (Letter)
18. Yamanishi K. Human herpesvirus 6. Microbiol Immunol 1992; 36:551-561
19. Asano Y, Grose C. Human herpesvirus type 6 infections. In: Classer R, Jones JF, eds. Herpesvirus infections. New York: Marcel-Dekker, 1994:227-244
20. Hall CB, Long CE, Schnabel K, Hall CB. Human herpes virus 6 infection in children: prospective evaluation for complications and reactivation. N Engl J Med 1994;331:432-438
21. Ablashi DV, Balachandran N, Josephs SF, et al. Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates. Virology 1991;184:545-552
22. Di Luca D, Dolcetti R, Mirandola P, et al. Human herpesvirus 6: a survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders. J Infect Dis 1994;170:211-215
23. Wang F-Z, Dahl H, Linde A, et al. Lymphotropic herpesviruses in allogeneic bone marrow transplantation. Blood 19996;88: 3516-3520
24. Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. Clin Microbiol Rev 1997;10:521-567
25. Yamanishi K, Okhuno T, Shiraki K, et al. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1988;1:1065-1067
26. Hall CB, Caserta MT, Schnabel KC, et al. Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A. Clin Infect Dis 1998;26:132-137
27. Jamieson BD, Ahmed R. T cell memory: long-term persistence of virus-specific cytotoxic T cells. J Exp Med 1989;169:1993-2005
28. Oehen S, Waldner HP, Kündig TH, et al. Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen. J Exp Med 1992;176:1273-1281
29. Leroux M, Schindler L, Braun R, et al. A whole-blood lymphoproliferation assay for measuring cellular immunity against herpes viruses. J Immunol Methods 1985;79:251-262
30. Sugden B. Epstein-Barr virus: a human pathogen inducing lymphoproliferation. Rev Infect Dis 1982;4:1048-1061
31. Wang F-Z, Dahl H, Ljungman P, Linde A. Lymphoproliferative responses to human herpesvirus-6 variant A and variant B in healthy adults. J Med Virol 1999;57:134-139
32. Yakushijin Y, Yasukawa M, Kobayashi Y. T-cell immune response to human herpesvirus-6 in healthy adults. Microbiol Immunol 1991;35:655-660
33. Johnson RT. The virology of demyelinating diseases. Ann Neurol 1994;36:554-560
34. Perron H, Garson JA, Bedin F, et al. Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis: the Collaborative Research Group on Multiple Sclerosis. Proc Natl Acad Sci USA 1977;9:7583-7588
35. Krueger GR, Koch B, Leyssens N, et al. Comparison of seroprevalences of human herpesvirus-6 and -7 in healthy blood donors from nine countries. Vox Sang 1998;75:193-197
36. Kikuta H, Nakane A, Lu H, et al. Interferon induction by human herpesvirus 6 infection in human mononuclear cells. J Infect Dis 1992;165:925-929
37. Flammand L, Gosselin J, D'Addarion M, et al. Human herpesvirus 6 induces interleukin-1 and tumor necrosis factor alpha, but not interleukin-6, in peripheral blood mononuclear cell cultures. J Virol 1991;65:5105-5110
38. Knox KK, Carrigan DR. Active human herpesvirus (HHV-6) infection of the central nervous system in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1995;9:69-73
39. Bouzid M, Buisson M, Morand P, et al. Different distribution of H1-H2 Epstein-Barr virus variant in oropharyngeal virus and in biopsies of Hodgkin's disease and in nasopharyngeal carcinomas from Algeria. Int J Cancer 1998;77:205-210
40. Chiang AK, Wong KY, Liang AC, Srivastava G. Comparative analysis of Epstein-Barr gene polymorphism in nasal T/NK-cell lymphomas and normal nasal tissues: implications of virus strain selection in malignancy. Int J Cancer 1999;80:356-364
41. Sawtell NM, Poon DK, Tansky CS, Thompson RL. The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivation. J Virol 1998;72:5343-5350
42. Klein M, Schoppel K, Amvrossiadis N, March M. Strain specific neutralization of cytomegalovirus isolates by human sera. J Virol 1999;73:878-886
43. Kosuge H, Isegawa Y, Yamanishi K. Nucleotide sequence analysis of a 30-kilobase-pair region of human herpesvirus-6B (HHV-6B) genome and strain-specific variations in major immediate early genes. Virus Res 1997;52:1-14
44. Reunanen M, Salmi A, Ilonen J, Herva E. Proliferation of multiple sclerosis cerebrospinal fluid lymphocytes after stimulation with measles virus antigens. Acta Neurol Scand 1980;62:293-299
45. Mokhtarian F, Shi Y, Zhu PF, Grob D. Immune responses, and autoimmune outcome, during virus infection of the central nervous system. Cell Immunol 1994;157:195-210
46. Greenstein JI, McFarland HF, Richert JR. Characterization of antigen-specific T cell in multiple sclerosis twins with elevated proliferative response to measles virus. J Immunol 1986;137: 546-560
47. Kim J-S, Park J-H, Lee K-H, Lee K-S. Detection of human herpesvirus 6 variant A sequence in multiple sclerosis. Presented at the AAN 51st Annual Meeting, Toronto, Ontario, Canada, April 17-24, 1999