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Volumn 107, Issue 2, 2000, Pages 161-166

The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis

Author keywords

Autoimmunity; Immunotherapy; Multiple sclerosis; Neuroprotection; Neurotrophic factors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MYELIN BASIC PROTEIN; NEUROTROPHIC FACTOR;

EID: 0034710340     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00233-2     Document Type: Conference Paper
Times cited : (216)

References (42)
  • 1
    • 0033104019 scopus 로고    scopus 로고
    • Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
    • Batchelor P.E., Liberatore G.T., Wong J.Y.F., Porritt M.J., Frerichs F., Donnan G.A., et al. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J. Neurosci. 19:1999;1708-1716.
    • (1999) J. Neurosci. , vol.19 , pp. 1708-1716
    • Batchelor, P.E.1    Liberatore, G.T.2    Wong, J.Y.F.3    Porritt, M.J.4    Frerichs, F.5    Donnan, G.A.6
  • 2
    • 0033152935 scopus 로고    scopus 로고
    • Clonally restricted production of the neurotrophins, brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors
    • Besser M., Wank R. Clonally restricted production of the neurotrophins, brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors. J. Immunol. 162:1999;6303-6306.
    • (1999) J. Immunol. , vol.162 , pp. 6303-6306
    • Besser, M.1    Wank, R.2
  • 3
    • 0026439389 scopus 로고
    • The cognitive paradigm and the immunological homunculus
    • Cohen I.R. The cognitive paradigm and the immunological homunculus. Immunol. Today. 13:1992;490-494.
    • (1992) Immunol. Today , vol.13 , pp. 490-494
    • Cohen, I.R.1
  • 4
    • 0028227144 scopus 로고
    • Future prospects for the management of multiple sclerosis
    • Compston A. Future prospects for the management of multiple sclerosis. Ann. Neurol. 36:1994;S146-S150.
    • (1994) Ann. Neurol. , vol.36 , pp. 146-S150
    • Compston, A.1
  • 5
    • 0027429536 scopus 로고
    • Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones
    • Ehrhard P.B., Erb P., Graumann U., Otten U. Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones. Proc. Natl. Acad. Sci. USA. 90:1993;10984-10988.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10984-10988
    • Ehrhard, P.B.1    Erb, P.2    Graumann, U.3    Otten, U.4
  • 6
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B., Matyszak M.K., Esiri M.M., Perry V.H. Axonal damage in acute multiple sclerosis lesions. Brain. 120:1997;393-399.
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 7
    • 0344780200 scopus 로고    scopus 로고
    • + T lymphocytes: Green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain
    • + T lymphocytes: Green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain. Nature Med. 5:1999;843-847.
    • (1999) Nature Med. , vol.5 , pp. 843-847
    • Flügel, A.1    Willem, M.2    Berkowicz, T.3    Wekerle, H.4
  • 8
    • 1842329729 scopus 로고    scopus 로고
    • Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
    • Gravel C., Götz R., Lorrain A., Sendtner M. Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Med. 3:1997;765-769.
    • (1997) Nature Med. , vol.3 , pp. 765-769
    • Gravel, C.1    Götz, R.2    Lorrain, A.3    Sendtner, M.4
  • 9
    • 0032516797 scopus 로고    scopus 로고
    • Accumulation of passively transferred primed T cells independently of their antigen specificity following nervous system trauma
    • Hirschberg D.L., Moalem G., He J., Mor F., Cohen I.R., Schwarz M. Accumulation of passively transferred primed T cells independently of their antigen specificity following nervous system trauma. J. Neuroimmunol. 89:1998;88-96.
    • (1998) J. Neuroimmunol. , vol.89 , pp. 88-96
    • Hirschberg, D.L.1    Moalem, G.2    He, J.3    Mor, F.4    Cohen, I.R.5    Schwarz, M.6
  • 10
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • Hofer M., Pagliusi S.R., Hohn A., Leibrock A., Barde Y.-A. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J. 9:1990;2459-2464.
    • (1990) EMBO J. , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, A.4    Barde, Y.-A.5
  • 11
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • Hohlfeld R. Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. Brain. 120:1997;865-916.
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 12
    • 0033103608 scopus 로고    scopus 로고
    • Activated human T cells, B cells and monocytes produce brain-derived neurotrophic factor (BDNF) in vitro and in brain lesions: A neuroprotective role of inflammation?
    • Kerschensteiner M., Gallmeier E., Behrens L., Klinkert W.E.F., Kolbeck R., Hoppe E., et al. Activated human T cells, B cells and monocytes produce brain-derived neurotrophic factor (BDNF) in vitro and in brain lesions: A neuroprotective role of inflammation? J. Exp. Med. 189:1999;865-870.
    • (1999) J. Exp. Med. , vol.189 , pp. 865-870
    • Kerschensteiner, M.1    Gallmeier, E.2    Behrens, L.3    Klinkert, W.E.F.4    Kolbeck, R.5    Hoppe, E.6
  • 13
    • 0025873435 scopus 로고
    • The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3
    • Klein R., Nanduri V., Jing S., Lamballe F., Tapley P., Bryant S., et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell. 66:1991;395-403.
    • (1991) Cell , vol.66 , pp. 395-403
    • Klein, R.1    Nanduri, V.2    Jing, S.3    Lamballe, F.4    Tapley, P.5    Bryant, S.6
  • 14
    • 0031467240 scopus 로고    scopus 로고
    • BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration
    • Kobayashi N.R., Fan D.-P., Giehl K.M., Bedard A.M., Wiegand S.J., Tetzlaff W. BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration. J. Neurosci. 17:1997;9583-9595.
    • (1997) J. Neurosci. , vol.17 , pp. 9583-9595
    • Kobayashi, N.R.1    Fan, D.-P.2    Giehl, K.M.3    Bedard, A.M.4    Wiegand, S.J.5    Tetzlaff, W.6
  • 15
    • 0028866451 scopus 로고
    • Gene transfer through the blood-nerve barrier: Nerve growth factor engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis
    • Kramer R., Zhang Y., Gehrmann J., Gold R., Thoenen H., Wekerle H. Gene transfer through the blood-nerve barrier: Nerve growth factor engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nature Med. 1:1995;1162-1166.
    • (1995) Nature Med. , vol.1 , pp. 1162-1166
    • Kramer, R.1    Zhang, Y.2    Gehrmann, J.3    Gold, R.4    Thoenen, H.5    Wekerle, H.6
  • 19
    • 0028943563 scopus 로고
    • Widespread neurotrophin receptor expression in the immune system and other nonneuronal rat tissues
    • Lomen-Hoerth C., Shooter E.M. Widespread neurotrophin receptor expression in the immune system and other nonneuronal rat tissues. J. Neurochem. 64:1995;1780-1789.
    • (1995) J. Neurochem. , vol.64 , pp. 1780-1789
    • Lomen-Hoerth, C.1    Shooter, E.M.2
  • 20
    • 0032528159 scopus 로고    scopus 로고
    • Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
    • McTigue D.M., Horner P.J., Stokes B.T., Gage F.H. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J. Neurosci. 18:1998;5354-5365.
    • (1998) J. Neurosci. , vol.18 , pp. 5354-5365
    • McTigue, D.M.1    Horner, P.J.2    Stokes, B.T.3    Gage, F.H.4
  • 21
    • 18744436601 scopus 로고    scopus 로고
    • Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques
    • Meinl E., Hoch R.M., Dornmair K., De Waal Malefijt R., Bontrop R.E., et al. Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques. Am. J. Pathol. 150:1997;445-453.
    • (1997) Am. J. Pathol. , vol.150 , pp. 445-453
    • Meinl, E.1    Hoch, R.M.2    Dornmair, K.3    De Waal Malefijt, R.4    Bontrop, R.E.5
  • 22
  • 23
    • 0033049143 scopus 로고    scopus 로고
    • Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
    • Moalem G., Leibowitz-Amit R., Yoles E., Mor F., Cohen I.R., Schwartz M. Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nature Med. 5:1999;49-55.
    • (1999) Nature Med. , vol.5 , pp. 49-55
    • Moalem, G.1    Leibowitz-Amit, R.2    Yoles, E.3    Mor, F.4    Cohen, I.R.5    Schwartz, M.6
  • 24
    • 0030860131 scopus 로고    scopus 로고
    • Adrenoleukodystrophy: Phenotype, genetics, pathogenesis and therapy
    • Moser H.W. Adrenoleukodystrophy: Phenotype, genetics, pathogenesis and therapy. Brain. 120:1997;1485-1508.
    • (1997) Brain , vol.120 , pp. 1485-1508
    • Moser, H.W.1
  • 25
    • 0020529974 scopus 로고
    • T lymphocyte line producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells
    • Naparstek Y., Ben-Nun A., Holoshitz J., Reshef T., Frenkel A., Rosenberg M., et al. T lymphocyte line producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells. Eur. J. Immunol. 13:1983;418-423.
    • (1983) Eur. J. Immunol. , vol.13 , pp. 418-423
    • Naparstek, Y.1    Ben-Nun, A.2    Holoshitz, J.3    Reshef, T.4    Frenkel, A.5    Rosenberg, M.6
  • 26
    • 0032510798 scopus 로고    scopus 로고
    • Neurotrophins inhibit class II inducibility of microglia: Involvement of the p75 receptor
    • Neumann H., Misgeld T., Matsumuro K., Wekerle H. Neurotrophins inhibit class II inducibility of microglia: Involvement of the p75 receptor. Proc. Natl. Acad. Sci. USA. 95:1998;5779-5784.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5779-5784
    • Neumann, H.1    Misgeld, T.2    Matsumuro, K.3    Wekerle, H.4
  • 27
    • 0032794046 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis: Recent trials and future perspectives
    • Noseworthy J.H., Gold R., Hartung H.-P. Treatment of multiple sclerosis: Recent trials and future perspectives. Curr. Opin. Neurol. 12:1999;279-293.
    • (1999) Curr. Opin. Neurol. , vol.12 , pp. 279-293
    • Noseworthy, J.H.1    Gold, R.2    Hartung, H.-P.3
  • 28
    • 0027245888 scopus 로고
    • Macrophages and inflammation in the central nervous system
    • Perry V.H., Andersson P.-B., Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:1993;268-273.
    • (1993) Trends Neurosci. , vol.16 , pp. 268-273
    • Perry, V.H.1    Andersson, P.-B.2    Gordon, S.3
  • 29
    • 0032055288 scopus 로고    scopus 로고
    • Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation?
    • Ransohoff R.M., Tani M. Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation? Trends Neurosci. 21:1998;154-159.
    • (1998) Trends Neurosci. , vol.21 , pp. 154-159
    • Ransohoff, R.M.1    Tani, M.2
  • 30
    • 0031849511 scopus 로고    scopus 로고
    • Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats
    • Rapalino O., Lazarov-Spiegler O., Agranov E., Velan G.J., Yoles E., Fraidakis M., et al. Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats. Nature Med. 4:1998;814-821.
    • (1998) Nature Med. , vol.4 , pp. 814-821
    • Rapalino, O.1    Lazarov-Spiegler, O.2    Agranov, E.3    Velan, G.J.4    Yoles, E.5    Fraidakis, M.6
  • 31
    • 0030870599 scopus 로고    scopus 로고
    • Clinical and molecular aspects of motor-neurone diseases: Animal models, neurotrophic factors and Bcl-2 oncoprotein
    • Sagot Y., Vejsada R., Kato A.C. Clinical and molecular aspects of motor-neurone diseases: Animal models, neurotrophic factors and Bcl-2 oncoprotein. Trends Pharmacol. Sci. 18:1997;330-337.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 330-337
    • Sagot, Y.1    Vejsada, R.2    Kato, A.C.3
  • 33
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz M., Moalem G., Leibowitz-Amit R., Cohen I.R. Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci. 22:1999;295-299.
    • (1999) Trends Neurosci. , vol.22 , pp. 295-299
    • Schwartz, M.1    Moalem, G.2    Leibowitz-Amit, R.3    Cohen, I.R.4
  • 34
    • 4243562216 scopus 로고    scopus 로고
    • Exacerbation of facial motor-neuron loss after facial nerve transection in severe combined immunodeficient (SCID) mice
    • Serpe C.J., Kohm A.P., Huppenbauer C.B., Sanders V.J., Jones K.J. Exacerbation of facial motor-neuron loss after facial nerve transection in severe combined immunodeficient (SCID) mice. J. Neurosci. RC7:1999;1-5.
    • (1999) J. Neurosci. , vol.7 , pp. 1-5
    • Serpe, C.J.1    Kohm, A.P.2    Huppenbauer, C.B.3    Sanders, V.J.4    Jones, K.J.5
  • 35
    • 0032436443 scopus 로고    scopus 로고
    • Expression of brain-derived neurotrophic factor protein in activated microglia of human immunodeficiency virus type 1 encephalitis
    • Soontornniyomkij V., Wang G., Pittman C.A., Wiley C.A., Achim C.L. Expression of brain-derived neurotrophic factor protein in activated microglia of human immunodeficiency virus type 1 encephalitis. Neuropathol. Appl. Neurobiol. 24:1999;453-460.
    • (1999) Neuropathol. Appl. Neurobiol. , vol.24 , pp. 453-460
    • Soontornniyomkij, V.1    Wang, G.2    Pittman, C.A.3    Wiley, C.A.4    Achim, C.L.5
  • 39
    • 0033103270 scopus 로고    scopus 로고
    • Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11 and transforming growth factor-beta 1 (TGF-beta 1) down-regulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia
    • Wei R.T., Jonakait G.M. Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11 and transforming growth factor-beta 1 (TGF-beta 1) down-regulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia. J. Neuroimmunol. 95:1999;8-18.
    • (1999) J. Neuroimmunol. , vol.95 , pp. 8-18
    • Wei, R.T.1    Jonakait, G.M.2
  • 42
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan Q., Elliott J., Snider W.D. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature. 360:1992;753-755.
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.