메뉴 건너뛰기




Volumn 105, Issue 3, 2000, Pages 399-408

The role of lymphocytes in allergic disease

Author keywords

Allergic rhinitis; Allergy; Asthma; Atopy; Chemokines; Cytokines; Hygiene hypothesis; Oligodeoxynucleotides; T(H)1 T(H)2 cells

Indexed keywords

CHEMOKINE; CYTOKINE; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034065298     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.104575     Document Type: Article
Times cited : (421)

References (115)
  • 1
    • 0000291799 scopus 로고
    • Ueber die specifischen granulationen des blutes
    • 1. Ehrlich P. Ueber die specifischen granulationen des Blutes. Arch Anat Physiol Lpz Physiol Abt 1879;3:571.
    • (1879) Arch Anat Physiol Lpz Physiol Abt , vol.3 , pp. 571
    • Ehrlich, P.1
  • 2
    • 0001391552 scopus 로고
    • Studien uber die veberempfindlichkeit
    • 2. Prausnitz C, Kustner H. Studien uber die Veberempfindlichkeit. Zbl Bakt Abt 1 1921;86:160.
    • (1921) Zbl Bakt Abt 1 , vol.86 , pp. 160
    • Prausnitz, C.1    Kustner, H.2
  • 3
    • 0014175692 scopus 로고
    • Identification of gamma-E-antibodies as a carrier of reaginic activity
    • 3. Ishizaka K, Ishizaka T. Identification of gamma-E-antibodies as a carrier of reaginic activity. J Immunol 1967;99:1187-98.
    • (1967) J Immunol , vol.99 , pp. 1187-1198
    • Ishizaka, K.1    Ishizaka, T.2
  • 4
    • 0014192793 scopus 로고
    • Raised levels of a new immunoglobulin class (IgND) in asthma
    • 4. Johansson SG. Raised levels of a new immunoglobulin class (IgND) in asthma. Lancet 1967;2:951-3.
    • (1967) Lancet , vol.2 , pp. 951-953
    • Johansson, S.G.1
  • 5
    • 0022625666 scopus 로고
    • A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma
    • 5. Coffman RL, Carty J. A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma. J Immunol 1986;136:949-54.
    • (1986) J Immunol , vol.136 , pp. 949-954
    • Coffman, R.L.1    Carty, J.2
  • 6
    • 0023705403 scopus 로고
    • IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants
    • 6. Del Prete G, Maggi E, Parronchi P, Chretien I, Tiri A, Macchia D, et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988;140:4193-8.
    • (1988) J Immunol , vol.140 , pp. 4193-4198
    • Del Prete, G.1    Maggi, E.2    Parronchi, P.3    Chretien, I.4    Tiri, A.5    Macchia, D.6
  • 7
    • 0023819822 scopus 로고
    • IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma
    • 7. Pene J, Rousset F, Briere F, Chretien I, Paliard X, Banchereau J, et al. IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. J Immunol 1988;141:1218-24.
    • (1988) J Immunol , vol.141 , pp. 1218-1224
    • Pene, J.1    Rousset, F.2    Briere, F.3    Chretien, I.4    Paliard, X.5    Banchereau, J.6
  • 8
    • 0022640843 scopus 로고
    • Two types of murine T cell clone, I: Definition according to profiles of lymphokine activities and secreted proteins
    • 8. Mosmann TR, Cherwinski H, Bond MW, Giedli MA, Coffman RL. Two types of murine T cell clone, I: definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedli, M.A.4    Coffman, R.L.5
  • 9
    • 0025807152 scopus 로고
    • Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
    • 9. Del Prete GF, De Carli M, Mastromauro C, Biagiotti R, Macchia D, Falagiani P, et al. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J Clin Invest 1991;88:346-50.
    • (1991) J Clin Invest , vol.88 , pp. 346-350
    • Del Prete, G.F.1    De Carli, M.2    Mastromauro, C.3    Biagiotti, R.4    Macchia, D.5    Falagiani, P.6
  • 10
    • 0031722440 scopus 로고    scopus 로고
    • The Th2 hypothesis in allergy - "Eppur si muove!"
    • 10. Romagnani S. The Th2 hypothesis in allergy - "Eppur si muove!" Allergy Clin Immunol Intern 1998;10:158-65.
    • (1998) Allergy Clin Immunol Intern , vol.10 , pp. 158-165
    • Romagnani, S.1
  • 11
    • 0025358166 scopus 로고
    • Evidence for compartmentalization of functional subsets of CD4+ T lymphocytes in atopic patients
    • 11. Wierenga EA, Snoek M, de Groot C, Chretien I, Bos JD, Jansen HM, et al. Evidence for compartmentalization of functional subsets of CD4+ T lymphocytes in atopic patients. J Immunol 1990;144:4651-6.
    • (1990) J Immunol , vol.144 , pp. 4651-4656
    • Wierenga, E.A.1    Snoek, M.2    De Groot, C.3    Chretien, I.4    Bos, J.D.5    Jansen, H.M.6
  • 12
    • 0025905118 scopus 로고
    • Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production
    • 12. Parronchi P, Macchia D, Piccinni M-P, Biswas P, Simonelli C, Maggi E, et al. Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc Natl Acad Sci U S A 1991;88:4538-42.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 4538-4542
    • Parronchi, P.1    Macchia, D.2    Piccinni, M.-P.3    Biswas, P.4    Simonelli, C.5    Maggi, E.6
  • 13
    • 0025760379 scopus 로고
    • Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
    • 13. Hamid Q, Azzawi M, Ying S, Moqbel R, Wardlaw AJ, Corrigan CJ, et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991;87:1541-6.
    • (1991) J Clin Invest , vol.87 , pp. 1541-1546
    • Hamid, Q.1    Azzawi, M.2    Ying, S.3    Moqbel, R.4    Wardlaw, A.J.5    Corrigan, C.J.6
  • 14
    • 0025864350 scopus 로고
    • High frequency of IL-4-producing CD4+ allergen specific T lymphocytes in atopic dermatitis lesional skin
    • 14. van der Heijden FL, Wirenga EA, Bos JD, Kapsenberg ML. High frequency of IL-4-producing CD4+ allergen specific T lymphocytes in atopic dermatitis lesional skin. J Invest Dermatol 1991;97:389-94.
    • (1991) J Invest Dermatol , vol.97 , pp. 389-394
    • Van Der Heijden, F.L.1    Wirenga, E.A.2    Bos, J.D.3    Kapsenberg, M.L.4
  • 15
    • 0027197709 scopus 로고
    • Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
    • 15. Del Prete GF, De Carli M, D'Elios MM, Maestrelli P, Ricci M, Fabbri L, et al. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur J Immunol 1993;23:1445-9.
    • (1993) Eur J Immunol , vol.23 , pp. 1445-1449
    • Del Prete, G.F.1    De Carli, M.2    D'Elios, M.M.3    Maestrelli, P.4    Ricci, M.5    Fabbri, L.6
  • 16
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
    • 16. Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178:2123-30.
    • (1993) J Exp Med , vol.178 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3    Marshall, J.D.4    Umetsu, D.T.5
  • 17
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • 17. Varney VA, Hamid Q, Gaga M, Ying S, Jacobson M, Frew AJ, et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92:644-51.
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.2    Gaga, M.3    Ying, S.4    Jacobson, M.5    Frew, A.J.6
  • 18
    • 0029126723 scopus 로고
    • Bee venom immunotherapy induces a shift in cytokine responses from a Th2 to a Th1 dominant pattern: Comparison of rush and conventional immunotherapy
    • 18. McHugh SM, Deighton J, Stewart AG, Lachmann PJ, Ewan PW. Bee venom immunotherapy induces a shift in cytokine responses from a Th2 to a Th1 dominant pattern: comparison of rush and conventional immunotherapy. Clin Exp Allergy 1995;15:828-38.
    • (1995) Clin Exp Allergy , vol.15 , pp. 828-838
    • McHugh, S.M.1    Deighton, J.2    Stewart, A.G.3    Lachmann, P.J.4    Ewan, P.W.5
  • 19
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-g secretion in specific allergen-stimulated T cell cultures
    • 19. Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-g secretion in specific allergen-stimulated T cell cultures. J Immunol 1995;54:4187-94.
    • (1995) J Immunol , vol.54 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Muller, U.R.6
  • 20
    • 0030689729 scopus 로고    scopus 로고
    • Induction of airway mucus production by T helper 2 (Th2) cells: A critical role for interleukin-4 in cell recruitment but not mucus production
    • 20. Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly K. Induction of airway mucus production by T helper 2 (Th2) cells: a critical role for interleukin-4 in cell recruitment but not mucus production. J Exp Med 1997;186:1737-47.
    • (1997) J Exp Med , vol.186 , pp. 1737-1747
    • Cohn, L.1    Homer, R.J.2    Marinov, A.3    Rankin, J.4    Bottomly, K.5
  • 21
    • 0032531571 scopus 로고    scopus 로고
    • IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1 cells
    • 21. Cohn L, Tepper JS, Bottomly K. IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1 cells. J Immunol 1998;161:3813-6.
    • (1998) J Immunol , vol.161 , pp. 3813-3816
    • Cohn, L.1    Tepper, J.S.2    Bottomly, K.3
  • 22
    • 0031830756 scopus 로고    scopus 로고
    • Requirements for allergen-induced airway hyperreactivity in T- and B-deficient mice
    • 22. Corry DB, Grunig G, Hadeiba H, Kurup VP, Warnock ML, Sheppard D, et al. Requirements for allergen-induced airway hyperreactivity in T- and B-deficient mice. Mol Med 1998;4:344-55.
    • (1998) Mol Med , vol.4 , pp. 344-355
    • Corry, D.B.1    Grunig, G.2    Hadeiba, H.3    Kurup, V.P.4    Warnock, M.L.5    Sheppard, D.6
  • 23
    • 0028346887 scopus 로고
    • Induction of interleukin 4 (IL-4) expression In T helper (Th) cells is not dependent on IL-4 from non-T cells
    • 23. Schmitz J, Thiel A, Kuhn R, Rajewsky K, Muller W, Assenmacher M, et al. Induction of interleukin 4 (IL-4) expression In T helper (Th) cells is not dependent on IL-4 from non-T cells. J Exp Med 1994;179:1349-53.
    • (1994) J Exp Med , vol.179 , pp. 1349-1353
    • Schmitz, J.1    Thiel, A.2    Kuhn, R.3    Rajewsky, K.4    Muller, W.5    Assenmacher, M.6
  • 24
    • 0032926518 scopus 로고    scopus 로고
    • STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells
    • 24. Miyata S, Matsuyama T, Kodama T, Nishioka Y, Takeda K, Akira S, et al. STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells. Clin Exp Allergy 1999;29:114-23.
    • (1999) Clin Exp Allergy , vol.29 , pp. 114-123
    • Miyata, S.1    Matsuyama, T.2    Kodama, T.3    Nishioka, Y.4    Takeda, K.5    Akira, S.6
  • 25
    • 0031311343 scopus 로고    scopus 로고
    • The role of interleukin-5 (IL-5) in vivo: Studies with IL-5 deficient mice
    • 25. Matthaei KI, Foster P, Young IG. The role of interleukin-5 (IL-5) in vivo: studies with IL-5 deficient mice. Mem Inst Oswaldo Cruz 1997;92:63-8.
    • (1997) Mem Inst Oswaldo Cruz , vol.92 , pp. 63-68
    • Matthaei, K.I.1    Foster, P.2    Young, I.G.3
  • 26
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnomalities and eotaxin production
    • 26. Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnomalities and eotaxin production. J Clin Invest 1999;103:779-88.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6
  • 27
    • 0032487434 scopus 로고    scopus 로고
    • Expression of interleukin-9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia and bronchial hyperresponsiveness
    • 27. Temann U-A, Geba GP, Rankin JA, Flavell RA. Expression of interleukin-9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia and bronchial hyperresponsiveness. J Exp Med 1998;188:1307-20.
    • (1998) J Exp Med , vol.188 , pp. 1307-1320
    • Temann, U.-A.1    Geba, G.P.2    Rankin, J.A.3    Flavell, R.A.4
  • 28
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiologic characterization of transgenic mice expressing interleukin-4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • 28. Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, et al. Phenotypic and physiologic characterization of transgenic mice expressing interleukin-4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci U S A 1996;93:7821-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 7821-7825
    • Rankin, J.A.1    Picarella, D.E.2    Geba, G.P.3    Temann, U.A.4    Prasad, B.5    DiCosmo, B.6
  • 29
    • 17444454662 scopus 로고    scopus 로고
    • Inlerleukin 5 expression in the lung epithelium of trasgenic mice leads to pulmonary changes pathognomonic of asthma
    • 29. Lee JJ, McGarry MP, Farmer SC, Denzler KL, Larson KA, Carrigan PE, et al. Inlerleukin 5 expression in the lung epithelium of trasgenic mice leads to pulmonary changes pathognomonic of asthma. J Exp Med 1997;185:2143-56.
    • (1997) J Exp Med , vol.185 , pp. 2143-2156
    • Lee, J.J.1    McGarry, M.P.2    Farmer, S.C.3    Denzler, K.L.4    Larson, K.A.5    Carrigan, P.E.6
  • 31
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • 31. Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994;12:227-57.
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 32
    • 0030935344 scopus 로고    scopus 로고
    • Cytokine regulation of host defense against parasitic gastrointestinal nematodes: Lessons from studies with rodent models
    • 32. Finkelman FD, Shea Donobue T, Goldhill J, Sullivan CA, Morris SC, Madden KB, et al. Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models. Annu Rev Immunol 1997;15: 505-33.
    • (1997) Annu Rev Immunol , vol.15 , pp. 505-533
    • Finkelman, F.D.1    Shea Donobue, T.2    Goldhill, J.3    Sullivan, C.A.4    Morris, S.C.5    Madden, K.B.6
  • 33
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • 33. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 34
    • 0031695515 scopus 로고    scopus 로고
    • Role of type 2 T helper (Th2) cytokines and leukemia inhibitory factor (LIF) produced by decidual T cells in unexplained recurrent abortions
    • 34. Piccinni MP, Beloni L, Livi C, Maggi E, Scarselli G, Romagnani S. Role of type 2 T helper (Th2) cytokines and leukemia inhibitory factor (LIF) produced by decidual T cells in unexplained recurrent abortions. Nat Med 1998;4:1020-4.
    • (1998) Nat Med , vol.4 , pp. 1020-1024
    • Piccinni, M.P.1    Beloni, L.2    Livi, C.3    Maggi, E.4    Scarselli, G.5    Romagnani, S.6
  • 35
    • 0033988247 scopus 로고    scopus 로고
    • MDC production by activated human T cells in vitro and in vivo. Preferential association with the production of type 2 cytokines
    • 35. Galli G, Chantry D, Annunziato F, Romagnani P, Cosmi L, Lazzeri E, et al. MDC production by activated human T cells in vitro and in vivo. Preferential association with the production of type 2 cytokines. Eur J Immunol 2000;30:204-10.
    • (2000) Eur J Immunol , vol.30 , pp. 204-210
    • Galli, G.1    Chantry, D.2    Annunziato, F.3    Romagnani, P.4    Cosmi, L.5    Lazzeri, E.6
  • 36
    • 0032532054 scopus 로고    scopus 로고
    • Effects of interleukin-4 and interferon-gamma on macrophage-derived chemokine production: An amplification circuit of polarized T helper 2 responses
    • 36. Bonecchi R, Sozzani S, Stine JT, Luini W, D'Amico G, Allavena P, et al. Effects of interleukin-4 and interferon-gamma on macrophage-derived chemokine production: an amplification circuit of polarized T helper 2 responses. Blood 1998;92:2668-71.
    • (1998) Blood , vol.92 , pp. 2668-2671
    • Bonecchi, R.1    Sozzani, S.2    Stine, J.T.3    Luini, W.4    D'Amico, G.5    Allavena, P.6
  • 37
    • 0030963614 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 CD4+ T cell responses: The alternative approaches
    • 37. Constant SL, Bottomly K. Induction of TH1 and TH2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol 1997;15:297-322.
    • (1997) Annu Rev Immunol , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 39
    • 0032213337 scopus 로고    scopus 로고
    • OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4 producing effectors
    • 39. Ohshima Y, Yang LP, Uchiyama T, Tanaka Y, Baum P, Sergerie M, et al. OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4 producing effectors. Blood 1998;92:3338-45.
    • (1998) Blood , vol.92 , pp. 3338-3345
    • Ohshima, Y.1    Yang, L.P.2    Uchiyama, T.3    Tanaka, Y.4    Baum, P.5    Sergerie, M.6
  • 40
    • 0031573660 scopus 로고    scopus 로고
    • Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation
    • 40. Tao X, Constant S, Jorritsma P, Bottomly K. Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. J Immunol 1997;159:5956-63.
    • (1997) J Immunol , vol.159 , pp. 5956-5963
    • Tao, X.1    Constant, S.2    Jorritsma, P.3    Bottomly, K.4
  • 41
    • 0029854221 scopus 로고    scopus 로고
    • Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NKL1 T cells
    • 41. Bendelac A, Hunziker R, Lantz O. Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NKL1 T cells. J Exp Med 1996;184:1285-93.
    • (1996) J Exp Med , vol.184 , pp. 1285-1293
    • Bendelac, A.1    Hunziker, R.2    Lantz, O.3
  • 42
    • 0026507228 scopus 로고
    • Reciprocal regulatory role of IFN-g and IL-4 on the in vitro development of human Th1 and Th2 cells
    • 42. Maggi E, Parronchi P, Manetti R, Simonelli C, Piccinni MP, Santoni-Rugiu F, et al. Reciprocal regulatory role of IFN-g and IL-4 on the in vitro development of human Th1 and Th2 cells. J Immunol 1992;148:2142-7.
    • (1992) J Immunol , vol.148 , pp. 2142-2147
    • Maggi, E.1    Parronchi, P.2    Manetti, R.3    Simonelli, C.4    Piccinni, M.P.5    Santoni-Rugiu, F.6
  • 43
    • 0026700113 scopus 로고
    • IL-4 and IFN(s) (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones
    • 43. Parronchi P, De Carli M, Manetti R, Simonelli C, Sampognaro S, Piccinni MP, et al. IL-4 and IFN(s) (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones. J Immunol 1992;149:2977-82.
    • (1992) J Immunol , vol.149 , pp. 2977-2982
    • Parronchi, P.1    De Carli, M.2    Manetti, R.3    Simonelli, C.4    Sampognaro, S.5    Piccinni, M.P.6
  • 44
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
    • 44. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G, et al. Natural killer cell stimulatory factor (interleukin-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med 1993;177:1199-204.
    • (1993) J Exp Med , vol.177 , pp. 1199-1204
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Piccinni, M.P.4    Maggi, E.5    Trinchieri, G.6
  • 46
    • 0030892136 scopus 로고    scopus 로고
    • Selective expression of an interleukin 12 receptor component by human T helper 1 cells
    • 46. Rogge L, Barberis L, Passini N, Presky DH, Gubler U, Sinigaglia F. Selective expression of an interleukin 12 receptor component by human T helper 1 cells. J Exp Med 1997;185:825-31.
    • (1997) J Exp Med , vol.185 , pp. 825-831
    • Rogge, L.1    Barberis, L.2    Passini, N.3    Presky, D.H.4    Gubler, U.5    Sinigaglia, F.6
  • 47
    • 15844374279 scopus 로고    scopus 로고
    • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
    • 47. Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996;380:630-2.
    • (1996) Nature , vol.380 , pp. 630-632
    • Shimoda, K.1    Van Deursen, J.2    Sangster, M.Y.3    Sarawar, S.R.4    Carson, R.T.5    Tripp, R.A.6
  • 48
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NF-AT family: Regulation and function
    • 48. Rao A, Luo C, Hogan PG. Transcription factors of the NF-AT family: regulation and function. Annu Rev Immunol 1997;15:707-47.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 49
    • 0033534375 scopus 로고    scopus 로고
    • Transcription factors in lymphocyte development - T and B cells get together
    • 49. Glimcher LH, Singh H. Transcription factors in lymphocyte development - T and B cells get together. Cell 1999;96:13-23.
    • (1999) Cell , vol.96 , pp. 13-23
    • Glimcher, L.H.1    Singh, H.2
  • 50
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • 50. Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 1997;276:589-92.
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 51
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • 51. Ye BH, Cattoretti G, Shen Q, Zhang J, Hawe N, de Waard R, et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet 1997;16:161-70.
    • (1997) Nat Genet , vol.16 , pp. 161-170
    • Ye, B.H.1    Cattoretti, G.2    Shen, Q.3    Zhang, J.4    Hawe, N.5    De Waard, R.6
  • 53
    • 0032476742 scopus 로고    scopus 로고
    • Essential role of nucler factor kB in the induction of eosinophilia in allergic airway inflammation
    • 53. Yang L, Cohn L, Zhang DH, Homer R, Ray A, Ray P. Essential role of nucler factor kB in the induction of eosinophilia in allergic airway inflammation. J Exp Med 1998;188:1739-50.
    • (1998) J Exp Med , vol.188 , pp. 1739-1750
    • Yang, L.1    Cohn, L.2    Zhang, D.H.3    Homer, R.4    Ray, A.5    Ray, P.6
  • 54
    • 0028858399 scopus 로고
    • Activation of the intereukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 ad CLEO elements
    • 54. Siegel MD, Zhang D-H, Ray P, Ray A. Activation of the intereukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 ad CLEO elements. J Biol Chem 1995;270:24548-55.
    • (1995) J Biol Chem , vol.270 , pp. 24548-24555
    • Siegel, M.D.1    Zhang, D.-H.2    Ray, P.3    Ray, A.4
  • 55
    • 0030604714 scopus 로고    scopus 로고
    • The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
    • 55. Ho CI, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 1996;85:973-83.
    • (1996) Cell , vol.85 , pp. 973-983
    • Ho, C.I.1    Hodge, M.R.2    Rooney, J.W.3    Glimcher, L.H.4
  • 56
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • 56. Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997;89:587-96.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 57
    • 0031460347 scopus 로고    scopus 로고
    • Genes that regulate interleukin-4 expression in T cells
    • 57. Szabo SJ, Glimcher LH, Ho I-C. Genes that regulate interleukin-4 expression in T cells. Curr Opin Immunol 1997;9:776-81.
    • (1997) Curr Opin Immunol , vol.9 , pp. 776-781
    • Szabo, S.J.1    Glimcher, L.H.2    Ho, I.-C.3
  • 58
    • 0032127176 scopus 로고    scopus 로고
    • The genetics and complexity of allergy and asthma
    • 58. Barnes KC, Marsh DG. The genetics and complexity of allergy and asthma. Immunol Today 1998;19:325-31.
    • (1998) Immunol Today , vol.19 , pp. 325-331
    • Barnes, K.C.1    Marsh, D.G.2
  • 60
    • 0030467722 scopus 로고    scopus 로고
    • Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation
    • 60. Jones AC, Miles EA, Warner JO, Colwell BM, Bryant TN, Warner JA. Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation. Pediatr Allergy Immunol 1996;7:109-116.
    • (1996) Pediatr Allergy Immunol , vol.7 , pp. 109-116
    • Jones, A.C.1    Miles, E.A.2    Warner, J.O.3    Colwell, B.M.4    Bryant, T.N.5    Warner, J.A.6
  • 61
    • 0032524991 scopus 로고    scopus 로고
    • Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T cell responses toward the Th2 cytokine profile
    • 61. Prescott SL, Macaubas C, Holt BJ, Smallacombe TB, Loh R, Sly PD, et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J Immunol 1998;160:4730-37.
    • (1998) J Immunol , vol.160 , pp. 4730-4737
    • Prescott, S.L.1    Macaubas, C.2    Holt, B.J.3    Smallacombe, T.B.4    Loh, R.5    Sly, P.D.6
  • 62
    • 0027207375 scopus 로고
    • Bidirectional cytokine onteractions in the maternal-fetal relationship: Is successful pregnancy a Th2 phenomenon?
    • 62. Wegmann TG, Lin H, Guilbert L, Mosmann RT. Bidirectional cytokine onteractions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today 1993;14:353-6.
    • (1993) Immunol Today , vol.14 , pp. 353-356
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3    Mosmann, R.T.4
  • 63
    • 0029036806 scopus 로고
    • Progesterone favors the development of human T helper (Th) cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 clones
    • 63. Piccinni MP, Giudizi MG, Biagiotti R, Annunziato F, Manetti R, Giannarini L, et al. Progesterone favors the development of human T helper (Th) cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 clones. J Immunol 1995;155:128-33.
    • (1995) J Immunol , vol.155 , pp. 128-133
    • Piccinni, M.P.1    Giudizi, M.G.2    Biagiotti, R.3    Annunziato, F.4    Manetti, R.5    Giannarini, L.6
  • 64
    • 0028593518 scopus 로고
    • Regulation of the development of type 2 T-helper cells in allergy
    • 64. Romagnani S. Regulation of the development of type 2 T-helper cells in allergy. Curr Opin Immunol 1994;6:838-46.
    • (1994) Curr Opin Immunol , vol.6 , pp. 838-846
    • Romagnani, S.1
  • 65
    • 0032536529 scopus 로고    scopus 로고
    • Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin suppresses allergen-induced airway eosinophilia
    • 65. Erb KJ, Holloway JW, Sobeck A, Moll H, Le Gros G. Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin suppresses allergen-induced airway eosinophilia. J Exp Med 1998;187:561-9.
    • (1998) J Exp Med , vol.187 , pp. 561-569
    • Erb, K.J.1    Holloway, J.W.2    Sobeck, A.3    Moll, H.4    Le Gros, G.5
  • 67
    • 0031014668 scopus 로고    scopus 로고
    • The inverse association between tuberculin responses and atopic disorders
    • 67. Shirikawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin responses and atopic disorders. Science 1997;275:77-9.
    • (1997) Science , vol.275 , pp. 77-79
    • Shirikawa, T.1    Enomoto, T.2    Shimazu, S.3    Hopkin, J.M.4
  • 68
    • 0030967169 scopus 로고    scopus 로고
    • Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus
    • 68. Matricardi PM, Rosmini F, Ferrigno L, Nisini R, Raoucetta M, Chionne P, et al. Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ 1997;314:999-1003.
    • (1997) BMJ , vol.314 , pp. 999-1003
    • Matricardi, P.M.1    Rosmini, F.2    Ferrigno, L.3    Nisini, R.4    Raoucetta, M.5    Chionne, P.6
  • 69
    • 0031663155 scopus 로고    scopus 로고
    • Reduced prevalence of allergic disease in patients with multiple sclerosis is associated with enhanced IL-12 production
    • 69. Tang L, Benjaponpitak S, DeKruyff RH, Umetsu DT. Reduced prevalence of allergic disease in patients with multiple sclerosis is associated with enhanced IL-12 production. J Allergy Clin Immunol 1998;102:428-35.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 428-435
    • Tang, L.1    Benjaponpitak, S.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 71
    • 0033135612 scopus 로고    scopus 로고
    • Atopy in children of families with an anthroposophic lifestyle
    • 71. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G. Atopy in children of families with an anthroposophic lifestyle. Lancet 1999;353:1485-8.
    • (1999) Lancet , vol.353 , pp. 1485-1488
    • Alm, J.S.1    Swartz, J.2    Lilja, G.3    Scheynius, A.4    Pershagen, G.5
  • 72
    • 0033089008 scopus 로고    scopus 로고
    • Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice
    • 72. MacLean JA, Sauty A, Luster AD, Drazen JM, De Sanctis GT. Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice. Am J Respir Cell Mol Biol 1999;20:379-87.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 379-387
    • MacLean, J.A.1    Sauty, A.2    Luster, A.D.3    Drazen, J.M.4    De Sanctis, G.T.5
  • 73
    • 0031844008 scopus 로고    scopus 로고
    • A murine model of allergic rhinitis: Studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin
    • 73. van de Rijn M, Melhop PD, Judkins A, Rothenberg ME, Luster AD, Oettgen HC. A murine model of allergic rhinitis: studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin. J Allergy Clin Immunol 1998;102:65-74.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 65-74
    • Van De Rijn, M.1    Melhop, P.D.2    Judkins, A.3    Rothenberg, M.E.4    Luster, A.D.5    Oettgen, H.C.6
  • 74
    • 0030953977 scopus 로고    scopus 로고
    • Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
    • 74. Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997;99:1329-39.
    • (1997) J Clin Invest , vol.99 , pp. 1329-1339
    • Hogan, S.P.1    Mould, A.2    Kikutani, H.3    Ramsay, A.J.4    Foster, P.S.5
  • 75
    • 0030810734 scopus 로고    scopus 로고
    • Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice
    • 75. Takeda K, Hamelmann E, Joetham A, Shultz L, Larsen GL, Irvin CG, et al. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997;186:449-54.
    • (1997) J Exp Med , vol.186 , pp. 449-454
    • Takeda, K.1    Hamelmann, E.2    Joetham, A.3    Shultz, L.4    Larsen, G.L.5    Irvin, C.G.6
  • 76
    • 10544256182 scopus 로고    scopus 로고
    • IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: Evidence against "intrinsic" asthma being a distinct immunopathologic entity
    • 76. Humbert M, Durham SR, Ying S, Kimmitt P, Barkans J, Assoufi B, et al. IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med 1996;154:1497-504.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1497-1504
    • Humbert, M.1    Durham, S.R.2    Ying, S.3    Kimmitt, P.4    Barkans, J.5    Assoufi, B.6
  • 77
    • 0033565618 scopus 로고    scopus 로고
    • Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions
    • 77. Brugnolo F, Annunziato F, Sampognaro S, Campi P, Manfredi M, Matucci A, et al. Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions. J Immunol 1999;163:1053-9.
    • (1999) J Immunol , vol.163 , pp. 1053-1059
    • Brugnolo, F.1    Annunziato, F.2    Sampognaro, S.3    Campi, P.4    Manfredi, M.5    Matucci, A.6
  • 78
    • 0028075291 scopus 로고
    • The role of adhesion molecules in human eosinophils and basophils recruitment
    • 78. Bochner BS, Schleimer RP. The role of adhesion molecules in human eosinophils and basophils recruitment. J Allergy Clin Immunol 1994;94:427-38.
    • (1994) J Allergy Clin Immunol , vol.94 , pp. 427-438
    • Bochner, B.S.1    Schleimer, R.P.2
  • 79
    • 0032966896 scopus 로고    scopus 로고
    • Chemokines and IL-5: Major players of eosinophil recruitment in asthma
    • 79. Teran LM. Chemokines and IL-5: major players of eosinophil recruitment in asthma. Clin Exp Allergy 1999;29:287-90.
    • (1999) Clin Exp Allergy , vol.29 , pp. 287-290
    • Teran, L.M.1
  • 80
    • 0031028365 scopus 로고    scopus 로고
    • Chemokine receptor usage by human eosinophils: The importance of CCR3 demonstrated using an antagonistic monoclonal antibody
    • 80. Heath H, Qin S, Rao P, Wu L, LaRosa G, Kassam N, et al. Chemokine receptor usage by human eosinophils: the importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J Clin Invest 1997;99:178-84.
    • (1997) J Clin Invest , vol.99 , pp. 178-184
    • Heath, H.1    Qin, S.2    Rao, P.3    Wu, L.4    LaRosa, G.5    Kassam, N.6
  • 81
    • 0030884894 scopus 로고    scopus 로고
    • High expression of the chemokine receptor CCR3 in human blood basophils: Role in activation by eotaxin, MCP-4, and other chemokines
    • 81. Uguccioni M, Mackay CR, Ochensberger B, Loetscher P, Rhis S, LaRosa GJ, et al. High expression of the chemokine receptor CCR3 in human blood basophils: role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest 1997;100:1137-43.
    • (1997) J Clin Invest , vol.100 , pp. 1137-1143
    • Uguccioni, M.1    Mackay, C.R.2    Ochensberger, B.3    Loetscher, P.4    Rhis, S.5    LaRosa, G.J.6
  • 82
    • 0033584240 scopus 로고    scopus 로고
    • T helper cell type 2 cytokine-mediated comitigenic responses and CCR3 expression during differentiation of human mast cells in vitro
    • 82. Ochi H, Hirani WM, Yuan Q, Friend DS, Austen KF, Boyce JA. T helper cell type 2 cytokine-mediated comitigenic responses and CCR3 expression during differentiation of human mast cells in vitro. J Exp Med 1999;190:267-80.
    • (1999) J Exp Med , vol.190 , pp. 267-280
    • Ochi, H.1    Hirani, W.M.2    Yuan, Q.3    Friend, D.S.4    Austen, K.F.5    Boyce, J.A.6
  • 83
    • 0032857213 scopus 로고    scopus 로고
    • Tryptase-chymase double-positive human mast cells express the eotaxin receptor CCR3 and are attracted by CCR3-binding chemokines
    • 83. Romagnani P, De Paulis A, Beltrame C, Annunziato F, Dente V, Maggi E, et al. Tryptase-chymase double-positive human mast cells express the eotaxin receptor CCR3 and are attracted by CCR3-binding chemokines. Am J Pathol 1999;155:1195-204.
    • (1999) Am J Pathol , vol.155 , pp. 1195-1204
    • Romagnani, P.1    De Paulis, A.2    Beltrame, C.3    Annunziato, F.4    Dente, V.5    Maggi, E.6
  • 84
    • 0030769920 scopus 로고    scopus 로고
    • Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
    • 84. Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 1997;277:2005-7.
    • (1997) Science , vol.277 , pp. 2005-2007
    • Sallusto, F.1    Mackay, C.R.2    Lanzavecchia, A.3
  • 85
    • 0031445441 scopus 로고    scopus 로고
    • Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma: Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells
    • 85. Ying S, Robinson DS, Meng Q, Rottman J, Kennedy R, Ringler DJ, et al. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma: association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur J Immunol 1997;27:3507-16.
    • (1997) Eur J Immunol , vol.27 , pp. 3507-3516
    • Ying, S.1    Robinson, D.S.2    Meng, Q.3    Rottman, J.4    Kennedy, R.5    Ringler, D.J.6
  • 86
    • 0033104696 scopus 로고    scopus 로고
    • Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells
    • 86. Li L, Xia Y, Nguyen A, Lai YH, Feng L, Mosmann TR, et al. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol 1999;162:2477-87.
    • (1999) J Immunol , vol.162 , pp. 2477-2487
    • Li, L.1    Xia, Y.2    Nguyen, A.3    Lai, Y.H.4    Feng, L.5    Mosmann, T.R.6
  • 87
    • 0033112651 scopus 로고    scopus 로고
    • Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts
    • 87. Teran LM, Mochizuki M, Bartels J, Valencia EL, Nakajima T, Hirai K, et al. Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. Am J Respir Cell Mol Biol 1999;20:777-86.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 777-786
    • Teran, L.M.1    Mochizuki, M.2    Bartels, J.3    Valencia, E.L.4    Nakajima, T.5    Hirai, K.6
  • 88
    • 0033178760 scopus 로고    scopus 로고
    • A novel human CC chemokine, eotaxin 3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinpìhils
    • 88. Shinkai A, Yoshisue H, Koike M, Shoji E, Nakagawa S, Saito A, et al. A novel human CC chemokine, eotaxin 3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinpìhils. J Immunol 1999;163:1602-10.
    • (1999) J Immunol , vol.163 , pp. 1602-1610
    • Shinkai, A.1    Yoshisue, H.2    Koike, M.3    Shoji, E.4    Nakagawa, S.5    Saito, A.6
  • 89
    • 0033198050 scopus 로고    scopus 로고
    • Eotaxin potentiates antigen-dependent basophil IL-4 production
    • 89. Devouassoux G, Metcalfe DD, Prussin C. Eotaxin potentiates antigen-dependent basophil IL-4 production. J Immunol 1999;163:2877-882.
    • (1999) J Immunol , vol.163 , pp. 2877-2882
    • Devouassoux, G.1    Metcalfe, D.D.2    Prussin, C.3
  • 90
    • 0026446005 scopus 로고
    • Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin
    • 90. Postlethwaite AE, Holness MA, Katai H, Raghow R. Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin. J Clin Invest 1992;90:1479-85.
    • (1992) J Clin Invest , vol.90 , pp. 1479-1485
    • Postlethwaite, A.E.1    Holness, M.A.2    Katai, H.3    Raghow, R.4
  • 91
    • 0028224194 scopus 로고
    • Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors: Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis
    • 91. Sempowski GD, Beckmann MP, Derdak S, Phipps RP. Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors: role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. J Immunol 1994;152:3606-14.
    • (1994) J Immunol , vol.152 , pp. 3606-3614
    • Sempowski, G.D.1    Beckmann, M.P.2    Derdak, S.3    Phipps, R.P.4
  • 93
    • 0031280279 scopus 로고    scopus 로고
    • Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung
    • 93. Jain-Vora S, Wert SE, Temann U-A, Rankin JA, Whitsett JA. Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung. Am J Respir Crit Care Med 1997;17:541-51.
    • (1997) Am J Respir Crit Care Med , vol.17 , pp. 541-551
    • Jain-Vora, S.1    Wert, S.E.2    Temann, U.-A.3    Rankin, J.A.4    Whitsett, J.A.5
  • 95
    • 0030236307 scopus 로고    scopus 로고
    • Transforming growth factor-β1 (TGF-β1) gene expression by eosinophils in asthmatic airway inflammation
    • 95. Ohno I, Nitta Y, Yamauchi K, Hoshi H, Honma M, Woolley K, et al. Transforming growth factor-β1 (TGF-β1) gene expression by eosinophils in asthmatic airway inflammation. Am J Respir Crit Care Med 1996;15:404-9.
    • (1996) Am J Respir Crit Care Med , vol.15 , pp. 404-409
    • Ohno, I.1    Nitta, Y.2    Yamauchi, K.3    Hoshi, H.4    Honma, M.5    Woolley, K.6
  • 96
    • 0028173026 scopus 로고
    • Airway targeted interleukin-6 in trasngenic mice: Uncoupling of airway inflammation and bronchial hyperreactivity
    • 96. DiCosmo BF, Geba GP, Picarella D, Elias JA, Rankin JA, Stripp BR, et al. Airway targeted interleukin-6 in trasngenic mice: uncoupling of airway inflammation and bronchial hyperreactivity. J Clin Invest 1994;94:2028-35.
    • (1994) J Clin Invest , vol.94 , pp. 2028-2035
    • DiCosmo, B.F.1    Geba, G.P.2    Picarella, D.3    Elias, J.A.4    Rankin, J.A.5    Stripp, B.R.6
  • 97
    • 0030476382 scopus 로고    scopus 로고
    • Targeted expression of IL-11 in the murine airways causes airways obstruction, bronchial remodeling and lymphocytic inflammation
    • 97. Tang W, Geba GP, Zheng T, Ray P, Homer RJ, Kuhn C III, et al. Targeted expression of IL-11 in the murine airways causes airways obstruction, bronchial remodeling and lymphocytic inflammation. J Clin Invest 1996;98:2845-53.
    • (1996) J Clin Invest , vol.98 , pp. 2845-2853
    • Tang, W.1    Geba, G.P.2    Zheng, T.3    Ray, P.4    Homer, R.J.5    Kuhn C. III6
  • 98
    • 0032742986 scopus 로고    scopus 로고
    • Overproduction of Th2-specific chemokines in NC/Nga mice exhbiting atopic dermatitis-like lesions
    • 98. Vestergaard C, Yoneyama H, Murai M, Nakamura K, Tamaki K, Terashima Y, et al. Overproduction of Th2-specific chemokines in NC/Nga mice exhbiting atopic dermatitis-like lesions. J Clin Invest 1999;104:1097-105.
    • (1999) J Clin Invest , vol.104 , pp. 1097-1105
    • Vestergaard, C.1    Yoneyama, H.2    Murai, M.3    Nakamura, K.4    Tamaki, K.5    Terashima, Y.6
  • 100
    • 0032522641 scopus 로고    scopus 로고
    • An antagonistic IL-4 mutant prevents type 1 allergy in the mouse: Inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo
    • 100. Grunewald SM, Werthmann A, Schnarr B, Klein CE, Brocker EB, Mohrs M, et al. An antagonistic IL-4 mutant prevents type 1 allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo. J Immunol 1998;160:4004-9.
    • (1998) J Immunol , vol.160 , pp. 4004-4009
    • Grunewald, S.M.1    Werthmann, A.2    Schnarr, B.3    Klein, C.E.4    Brocker, E.B.5    Mohrs, M.6
  • 101
    • 0029371991 scopus 로고
    • Involvement of IL-5 in a murine model of allergic pulmonary inflammation: Prophylactic and theraputic effect of an anti-IL-5 antibody
    • 101. Kung TT, Stelts DM, Zurcher JA, Adams GK, Egan RW, Kreutner W, et al. Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and theraputic effect of an anti-IL-5 antibody. Am J Respir Cell Mol Biol 1995;13:360-5.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 360-365
    • Kung, T.T.1    Stelts, D.M.2    Zurcher, J.A.3    Adams, G.K.4    Egan, R.W.5    Kreutner, W.6
  • 102
    • 0030888557 scopus 로고    scopus 로고
    • Selective suppression of IL-5 synthesis by OM-01 - Pinpoint treatment of atopic diseases by IL-5 gene transcription inhibitor
    • 102. Okudaira H, Mori A, Mikami T, Kaminuma O, Ohmura T, Hoshino A, et al. Selective suppression of IL-5 synthesis by OM-01 - pinpoint treatment of atopic diseases by IL-5 gene transcription inhibitor. Int Arch Allergy Immunol 1997;113:331-4.
    • (1997) Int Arch Allergy Immunol , vol.113 , pp. 331-334
    • Okudaira, H.1    Mori, A.2    Mikami, T.3    Kaminuma, O.4    Ohmura, T.5    Hoshino, A.6
  • 103
    • 0029563448 scopus 로고
    • Anti-IgE therapy
    • 103. Jardieu P. Anti-IgE therapy. Curr Opin Immunol 1995;7:779-82.
    • (1995) Curr Opin Immunol , vol.7 , pp. 779-782
    • Jardieu, P.1
  • 104
    • 17644441947 scopus 로고    scopus 로고
    • The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: Efficacy, safety, and pharmacokinetics
    • 104. Corne J, Djukanovic R, Thomas L, Warner J, Botta L, Grandordy B, et al. The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics. J Clin Invest 1997;99:879-87.
    • (1997) J Clin Invest , vol.99 , pp. 879-887
    • Corne, J.1    Djukanovic, R.2    Thomas, L.3    Warner, J.4    Botta, L.5    Grandordy, B.6
  • 105
    • 0029661918 scopus 로고    scopus 로고
    • TH2 cells in allergic inflammation: A target of immunotherapy
    • 105. Lord CJM, Lamb JR. TH2 cells in allergic inflammation: a target of immunotherapy. Clin Exp Allergy 1996;26:756-65.
    • (1996) Clin Exp Allergy , vol.26 , pp. 756-765
    • Lord, C.J.M.1    Lamb, J.R.2
  • 106
    • 0030239669 scopus 로고    scopus 로고
    • Altered T cell ligands derived from a major house dust mite allergen enhance IFN-gamma but not IL-4 production by human CD4+ T cells
    • 106. Tsitoura DC, Verhoef A, Gelder CM, O'Heir R, Lamb JR. Altered T cell ligands derived from a major house dust mite allergen enhance IFN-gamma but not IL-4 production by human CD4+ T cells. J Immunol 1996;157:2160-5.
    • (1996) J Immunol , vol.157 , pp. 2160-2165
    • Tsitoura, D.C.1    Verhoef, A.2    Gelder, C.M.3    O'Heir, R.4    Lamb, J.R.5
  • 107
    • 0030443348 scopus 로고    scopus 로고
    • Altered TCR ligands affect antigen-presenting cell responses: Up-regulation of IL-12 by an analogue peptide
    • 107. Matsuoka T, Kohrogi H, Ando M, Nishimura Y, Matsushita S. Altered TCR ligands affect antigen-presenting cell responses: up-regulation of IL-12 by an analogue peptide. J Immunol 1996;157:4837-43.
    • (1996) J Immunol , vol.157 , pp. 4837-4843
    • Matsuoka, T.1    Kohrogi, H.2    Ando, M.3    Nishimura, Y.4    Matsushita, S.5
  • 108
    • 0032213360 scopus 로고    scopus 로고
    • Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels
    • 108. Hofstra CL, Van Ark I, Hofman G, Kool M, Nijkamp FP, Van Oosterhout AJ. Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels. J Immunol 1998;161:5054-60.
    • (1998) J Immunol , vol.161 , pp. 5054-5060
    • Hofstra, C.L.1    Van Ark, I.2    Hofman, G.3    Kool, M.4    Nijkamp, F.P.5    Van Oosterhout, A.J.6
  • 109
    • 0032536529 scopus 로고    scopus 로고
    • Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin suppresses allergen-induced airway eosinophilia
    • 109. Erb KJ, Holloway JW, Sobeck A, Moll H, Le Gros G. Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin suppresses allergen-induced airway eosinophilia. J Exp Med 1998;187:561-9.
    • (1998) J Exp Med , vol.187 , pp. 561-569
    • Erb, K.J.1    Holloway, J.W.2    Sobeck, A.3    Moll, H.4    Le Gros, G.5
  • 110
    • 0029818390 scopus 로고    scopus 로고
    • Inhibition of specific IgE response in vivo by allergen-gene transfer
    • 110. Hsu CH, Chua KY, Tao MH, Huang SK, Hsieh KH. Inhibition of specific IgE response in vivo by allergen-gene transfer. Int Immunol 1996;8:1405-11.
    • (1996) Int Immunol , vol.8 , pp. 1405-1411
    • Hsu, C.H.1    Chua, K.Y.2    Tao, M.H.3    Huang, S.K.4    Hsieh, K.H.5
  • 111
    • 0029664297 scopus 로고    scopus 로고
    • Preferential induction of aTh1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
    • 111. Raz E, Tighe E, Sato Y, Corr M, Dudler JA, Roman M, et al. Preferential induction of aTh1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A 1996;93:5141-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5141-5145
    • Raz, E.1    Tighe, E.2    Sato, Y.3    Corr, M.4    Dudler, J.A.5    Roman, M.6
  • 112
    • 0032534602 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
    • 112. Broide D, Schwarze J, Tighe H, Gifford T, Nguyen MD, Malek S, et al. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol 1998;161:7054-62.
    • (1998) J Immunol , vol.161 , pp. 7054-7062
    • Broide, D.1    Schwarze, J.2    Tighe, H.3    Gifford, T.4    Nguyen, M.D.5    Malek, S.6
  • 114
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
    • 114. Chu RS, Targoni OS, Krieg AM, Lehmann PV, Harding CV. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J Exp Med 1997;186:1623-31.
    • (1997) J Exp Med , vol.186 , pp. 1623-1631
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 115
    • 0033485399 scopus 로고    scopus 로고
    • Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into type 1 T helper (Th1) effectors
    • 115. Parronchi P, Brugnolo F, Annunziato F, Manuelli C, Sampognaro S, Mavilia C, et al. Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into type 1 T helper (Th1) effectors. J Immunol 1999;163:5946-53.
    • (1999) J Immunol , vol.163 , pp. 5946-5953
    • Parronchi, P.1    Brugnolo, F.2    Annunziato, F.3    Manuelli, C.4    Sampognaro, S.5    Mavilia, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.