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Volumn 9, Issue 6, 1997, Pages 776-781

Genes that regulate interleukin-4 expression in T cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 4; PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

EID: 0031460347     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(97)80177-X     Document Type: Article
Times cited : (71)

References (47)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A: Functional diversity of helper T • lymphocytes. Nature 1996, 31:787-793. A concise and very current review of the cellular and molecular signals that regulate Th cell phenotype development both in vitro and in vivo. The authors also discuss how the balance between Th1 and Th2 immune responses influences the outcome of infectious, allergic, and autoimmune diseases.
    • (1996) Nature , vol.31 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 3
    • 0030175602 scopus 로고    scopus 로고
    • Type 1 and type 2: A fundamental dichotomy for all T-cell subsets
    • Carter LL, Dutton RA: Type 1 and type 2: a fundamental dichotomy for all T-cell subsets. Curr Opin Immunol 1996, 8:336-342.
    • (1996) Curr Opin Immunol , vol.8 , pp. 336-342
    • Carter, L.L.1    Dutton, R.A.2
  • 4
    • 0343773445 scopus 로고    scopus 로고
    • IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease
    • Rocken M, Racke M, Shevach EM: IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease. Immunol Today 1996, 17:225-231.
    • (1996) Immunol Today , vol.17 , pp. 225-231
    • Rocken, M.1    Racke, M.2    Shevach, E.M.3
  • 5
    • 0013480258 scopus 로고    scopus 로고
    • Molecular mechanism controlling interleukin-4 synthesis
    • Casolaro V, Georas SN, Marone G, Ono SJ: Molecular • mechanism controlling interleukin-4 synthesis. Forma 1996, 7:11-19. A review of the biochemical signals required for transcriptional activation of the IL-4 gene. This review also presents a complete picture of the complexity of IL-4 gene regulation in both mouse and humans, with a detailed analysis of the cis-elements and trans-acting factors that control IL-4 gene transactivation.
    • (1996) Forma , vol.7 , pp. 11-19
    • Casolaro, V.1    Georas, S.N.2    Marone, G.3    Ono, S.J.4
  • 7
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao A, Luo C, Hogan PG: Transcription factors of the NFAT • family: regulation and function. Annu Rev Immunol 1997, 15:707-747. A comprehensive review of the NF-AT family members with detailed descriptions of the biochemical mechanisms regulating the induction and suppression of NF-AT activity. In addition, the authors discuss the DNA binding activity of the NF-AT proteins, their interactions with other transcription factors, and the genes regulated by NF-AT proteins.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 11
    • 0029053852 scopus 로고
    • Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
    • Hoey T, Sun Y-L, Williamson K, Xu X: Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 1995, 2:461-472.
    • (1995) Immunity , vol.2 , pp. 461-472
    • Hoey, T.1    Sun, Y.-L.2    Williamson, K.3    Xu, X.4
  • 12
    • 0029125831 scopus 로고
    • NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity
    • Ho SN, Thomas DJ, Timmerman LA, Li X, Francke U, Crabtree GR: NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity. J Biol Chem 1995, 270:19898-19907.
    • (1995) J Biol Chem , vol.270 , pp. 19898-19907
    • Ho, S.N.1    Thomas, D.J.2    Timmerman, L.A.3    Li, X.4    Francke, U.5    Crabtree, G.R.6
  • 14
    • 0027305687 scopus 로고
    • Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: Roles for NF-Y and NF-ATc
    • Szabo SJ, Gold JS, Murphy TL, Murphy KM: Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol Cell Biol 1993, 13:4793-4805.
    • (1993) Mol Cell Biol , vol.13 , pp. 4793-4805
    • Szabo, S.J.1    Gold, J.S.2    Murphy, T.L.3    Murphy, K.M.4
  • 16
    • 0030949834 scopus 로고    scopus 로고
    • Expression of NFAT-family proteins in normal human T cells
    • Lyakh L, Ghosh P, Rice NR: Expression of NFAT-family proteins in normal human T cells. Mol Cell Biol 1997, 17:2475-2484.
    • (1997) Mol Cell Biol , vol.17 , pp. 2475-2484
    • Lyakh, L.1    Ghosh, P.2    Rice, N.R.3
  • 17
    • 0028157768 scopus 로고
    • A common factor regulates both Th1 - and Th2-specific cytokine gene expression
    • Rooney JW, Hodge MR, McCaffrey PG, Rao A, Glimcher LH: A common factor regulates both Th1 - and Th2-specific cytokine gene expression. EMBO J 1994, 13:625-633.
    • (1994) EMBO J , vol.13 , pp. 625-633
    • Rooney, J.W.1    Hodge, M.R.2    McCaffrey, P.G.3    Rao, A.4    Glimcher, L.H.5
  • 18
    • 0344852190 scopus 로고    scopus 로고
    • Differential interaction of nuclear factor with the PRE-1 enhancer element of the human IL-4 promoter in different T cell subsets
    • Li-Weber M, Salgame P, Hu C, Davydov IV, Krammer PH: Differential interaction of nuclear factor with the PRE-1 enhancer element of the human IL-4 promoter in different T cell subsets. J Immunol 1997, 158:1195-1200.
    • (1997) J Immunol , vol.158 , pp. 1195-1200
    • Li-Weber, M.1    Salgame, P.2    Hu, C.3    Davydov, I.V.4    Krammer, P.H.5
  • 19
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
    • Rooney JW, Hoey T, Glimcher LH: Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 1995, 2:473-483.
    • (1995) Immunity , vol.2 , pp. 473-483
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 20
    • 0030002617 scopus 로고    scopus 로고
    • Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice
    • Hodge MR, Ranger AM, de la Brousse FC, Hoey T, Grusby MJ, •• Glimcher LH: Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity 1996, 4:397-405. Due to tKe overlapping expression of NF-AT family members in various immune effector cells, there is uncertainty regarding the specificity and function of the various NF-AT proteins. This paper begins to elucidate the specific roles that each NF-AT family member plays in the immune response.
    • (1996) Immunity , vol.4 , pp. 397-405
    • Hodge, M.R.1    Ranger, A.M.2    De La Brousse, F.C.3    Hoey, T.4    Grusby, M.J.5    Glimcher, L.H.6
  • 21
    • 0029882657 scopus 로고    scopus 로고
    • An enhanced immune response in mice lacking the transcription factor NFAT1
    • Xanthoudakis S, Viola JPB, Shaw KTY, Lou C, Wallace JD, Bozza •• PT, Luk DC, Curran T, Rao A: An enhanced immune response in mice lacking the transcription factor NFAT1, Science 1996, 272(5263):892-895. See 20••. Due to the overlapping expression of NF-AT family members in various immune effector cells, there is uncertainty regarding the specificity and function of the various NF-AT proteins. This paper begins to elucidate the specific roles that each NF-AT family member plays in the immune response.
    • (1996) Science , vol.272 , Issue.5263 , pp. 892-895
    • Xanthoudakis, S.1    Viola, J.P.B.2    Shaw, K.T.Y.3    Lou, C.4    Wallace, J.D.5    Bozza, P.T.6    Luk, D.C.7    Curran, T.8    Rao, A.9
  • 22
    • 0031034051 scopus 로고    scopus 로고
    • Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells
    • Rincon M, Flavell RA: Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol Cell Biol 1997, 17:1522-1534.
    • (1997) Mol Cell Biol , vol.17 , pp. 1522-1534
    • Rincon, M.1    Flavell, R.A.2
  • 23
    • 0031180393 scopus 로고    scopus 로고
    • Differential expression of transcription directed by a discrete NF-AT binding element from the IL-4 promoter in naive and effector CD4 T cells
    • Aune TM, Flavell RA: Differential expression of transcription directed by a discrete NF-AT binding element from the IL-4 promoter in naive and effector CD4 T cells. J Immunol 1997, 159:36-43.
    • (1997) J Immunol , vol.159 , pp. 36-43
    • Aune, T.M.1    Flavell, R.A.2
  • 24
    • 0030474682 scopus 로고    scopus 로고
    • NF-AT-driven interleukin-4 transcription potentiated by NIP45
    • Hodge MR, Chun HJ, Rengarajan J, Alt A, Lieberson R, Glimcher •• LH: NF-AT-driven interleukin-4 transcription potentiated by NIP45. Science 1996, 274:1903-1905. This paper details the identification of NIP45, a coactivator of the IL-4 gene that interacts with NF-AT family members. IL-4 transcription is strongly induced by the synergistic combination of NIP45, NF-AT, and c-Maf. The role of NIP45 or similar proteins in the expression of other cytokine genes remains an important question.
    • (1996) Science , vol.274 , pp. 1903-1905
    • Hodge, M.R.1    Chun, H.J.2    Rengarajan, J.3    Alt, A.4    Lieberson, R.5    Glimcher, L.H.6
  • 26
    • 0028857929 scopus 로고
    • Novel NF-AT sites that mediate activation of the interleukin-2 promoter in response to T cell receptor stimulation
    • Rooney JW, Sun YA, Glimcher LH, Hoey T: Novel NF-AT sites that mediate activation of the interleukin-2 promoter in response to T cell receptor stimulation. Mol Cell Biol 1995, 15:6299-6310.
    • (1995) Mol Cell Biol , vol.15 , pp. 6299-6310
    • Rooney, J.W.1    Sun, Y.A.2    Glimcher, L.H.3    Hoey, T.4
  • 30
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler C, Darnell JE Jr: Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 1995, 64:621-651.
    • (1995) Annu Rev Biochem , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell J.E., Jr.2
  • 31
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides H, Reich NC: Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 1993, 262:1265-1267.
    • (1993) Science , vol.262 , pp. 1265-1267
    • Kotanides, H.1    Reich, N.C.2
  • 32
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan MH, Schindler U, Smiley ST, Grusby MJ: Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996, 4:313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 36
    • 0030604714 scopus 로고    scopus 로고
    • The proto-oncogene c-Maf is responsible for tissue-specific expression of interleukin-4
    • Ho IC, Hodge MR, Rooney JR, Glimcher LH: The proto-oncogene c-Maf is responsible for tissue-specific expression of interleukin-4. Cell 1996, 85:973-983. The first identification of a transcription factor expressed in a Th phenotype specific fashion. c-Maf is expressed in Th2 cells but not Th1 cells and it appears to play an important role in Th2 specific IL-4 gene expression. c-Maf may be the first of many still to be identified cytokine-specific nuclear factors necessary for the phenotype restricted expression of Th cytokines.
    • (1996) Cell , vol.85 , pp. 973-983
    • Ho, I.C.1    Hodge, M.R.2    Rooney, J.R.3    Glimcher, L.H.4
  • 37
    • 0028053782 scopus 로고
    • A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins
    • Kerppola TK, Curran T: A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins. Oncogene 1994, 9:3149-3158.
    • (1994) Oncogene , vol.9 , pp. 3149-3158
    • Kerppola, T.K.1    Curran, T.2
  • 39
    • 0025736807 scopus 로고
    • Human GATA-3: A lineage-restricted transcription factor that regulates the expression of the T cell receptor α gene
    • Ho IC, Vorhees P, Marin N, Oakley BK, Tsai SF, Orkin SH, Leiden JM: Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor α gene. EMBO J 1991, 10:1187-1192.
    • (1991) EMBO J , vol.10 , pp. 1187-1192
    • Ho, I.C.1    Vorhees, P.2    Marin, N.3    Oakley, B.K.4    Tsai, S.F.5    Orkin, S.H.6    Leiden, J.M.7
  • 40
    • 0026345833 scopus 로고
    • Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor δ gene enhancer
    • Ko U, Yamamoto M, Leonard MW, George KM, Ting P, Engel JD: Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor δ gene enhancer. Mol Cell Biol 1991, 11:2778-2784.
    • (1991) Mol Cell Biol , vol.11 , pp. 2778-2784
    • Ko, U.1    Yamamoto, M.2    Leonard, M.W.3    George, K.M.4    Ting, P.5    Engel, J.D.6
  • 41
    • 0029828994 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is required for development of the T-cell lineage
    • Ting CN, Olson MC, Barton KP, Leiden JM: Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 1996, 384:474-478.
    • (1996) Nature , vol.384 , pp. 474-478
    • Ting, C.N.1    Olson, M.C.2    Barton, K.P.3    Leiden, J.M.4
  • 42
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W, Flavell RA: The transcription factor GATA-3 is •• necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-596. The transcription factor GATA-3, initially shown to be essential for T cell lineage formation, may also be essential for the restricted pattern of cytokine gene expression in developing Th2 cells. GATA-3 may be a key regulator of the Th2 type cytokines IL-4, IL-5, IL-6, and IL-10.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 43
    • 0030764961 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls the Th2-specific expression of the interleukin-5 gene
    • Zhang DH, Cohn L, Ray P, Bottomly K, Ray A: Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls the Th2-specific expression of the interleukin-5 gene. J Biol Chem 1997, 272:21597-21603.
    • (1997) J Biol Chem , vol.272 , pp. 21597-21603
    • Zhang, D.H.1    Cohn, L.2    Ray, P.3    Bottomly, K.4    Ray, A.5
  • 44
    • 0028139174 scopus 로고
    • The role of interleukin 12 in the immune response, disease and therapy
    • Trinchieri G, Scott P: The role of interleukin 12 in the immune response, disease and therapy. Immunol Today 1994, 15:460-463.
    • (1994) Immunol Today , vol.15 , pp. 460-463
    • Trinchieri, G.1    Scott, P.2


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