Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 20, Issue 3, 1999, Pages 379-387

  MacLean, James A ^a   Sauty, Alain ^b   Luster, Andrew D ^b   Drazen, Jeffrey M ^b   De Sanctis, George T ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

CHEMOKINE; IMMUNOGLOBULIN E; MESSENGER RNA; OVALBUMIN;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; ASTHMA; B LYMPHOCYTE; CYTOLOGY; GENETICS; IMMUNOLOGY; LOEFFLER PNEUMONIA; LUNG; LUNG LAVAGE; MOUSE; MOUSE MUTANT; PATHOLOGY; RESPIRATORY TRACT ALLERGY;

ANIMALS; ANTIBODY SPECIFICITY; ASTHMA; B-LYMPHOCYTES; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; IMMUNOGLOBULIN E; LUNG; MICE; MICE, MUTANT STRAINS; OVALBUMIN; PULMONARY EOSINOPHILIA; RESPIRATORY HYPERSENSITIVITY; RNA, MESSENGER;

EID: 0033089008     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.20.3.3291     Document Type: Article

References (39)

1. Nakajima, H., I. Iwamoto, S. Tomoe, R. Matsumura, H. Tomioka, K. Takatsu, and S. Yoshido. 1992. CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltralion into the mouse trachea. Am. Rev. Respir. Dis. 146:374-377.
2. Renz, H., H. R. Smith, J. E. Henson, B. S. Ray, C. G. Irvin, and E. W. Gelfand. 1992. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J. Allergy Clin. Immunol. 89:1127-1138.
3. Gavett, S., X. Chen, F. Finkelman, and M. Wills-Karp. 1994. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10:587-593.
4. Kung, T. T., H. Jones, G. Adams, S. P. Umland, W. Kreutner, R. W. Egan, R. W. Chapman, and A. S. Watnick. 1994. Characterization of a murine model of allergic pulmonary inflammation. Int. Arch. Allergy Immunol. 105:83-90.
5. Garlisi, C., A. Falcone, T. Kung, D. Stelts, K. Pennline, A. Beavis, S. Smith, R. Egan, and S. Umland. 1995. T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice. Clin. Immunol. Immunopathol. 75:75-83.
6. Corry, D., H. Folkesson, M. Warnock, D. Erle, M. Matthay, J. Wiener-Kronish, and R. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109-117.
7. MacLean, J., R. Ownbey, and A. Luster. 1996. T cell-dependent regulation of cotaxin in antigen-induced pulmonary eosinophilia. J. Exp. Med. 184: 1461-1469.
8. Gavett, S., D. O'Hearn, C. Karp, E. Patel, B. Schofield, F. Finkelman, and M. Wills-Karp. 1997. Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am. J. Physiol. 272:L253-L261.
9. Hamelmann, E., A. Oshiba, J. Schwarze, K. Bradley, J. Loader, G. L. Larsen, and E. W. Gelfand. 1997. Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am. J. Respir. Cell Mol. Biol. 16:674-682.
10. Oshiba, A., E. Hamelmann, K. Takeda, K. L. Bradley, J. E. Loader, G. L. Larsen, and E. W. Gelfand. 1996. Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin E and IgG1 in mice. J. Clin. Invest. 97:1398-1408.
11. Korsgren, M., J. S. Erjefalt, O. Korsgren, F. Sundler, and C. G. A. Persson. 1997. Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice. J. Exp. Med. 185:885-892.
12. Hamelmann, E., A. Vella, A. Oshiba, J. Kappler, P. Marrack, and E. Gelfand. 1997. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc. Natl. Acad. Sci. USA 94:1350-1355.
13. Kitamura, D., J. Roes, R. Kuhn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350:423-426.
14. Martin, T. R., N. P. Gerard, S. J. Galli, and J. M. Drazen. 1988. Pulmonary responses to bronchoconstrictor agonists in the mouse. J. Appl. Physiol. 64:2318-2323.
15. De Sanctis, G. T., M. Merchant, D. R. Beier, R. D. Dredge, J. K. Grobholz, T. R. Martin, E. S. Lander, and J. M. Drazen. 1995. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat. Genet. 11:150-154.
16. Chirgwin, J., A. Przybyla, R. MacDonald, and W. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources rich in ribonuclease. Biochemistry 18:5294-5299.
17. Luster, A., and P. Leder. 1993. IP-10, a -C-X-C- chemokine, elicits a potent thymus-dependent antitumor response in vivo. J. Exp. Med. 178:1057-1065.
18. MacLean, J., Z. Su, R. Colvin, and J. Wong. 1995. Anti-CD3:anti-IL-2 receptor bispecific monoclonal antibody mediated immunomodulation: low systemic toxicity, differential effect on lymphoid tissue, and inhibition of cell-mediated hypersensitivity. J. Immunol. 155:3674-3682.
19. Sarafi, M., E. Garcia-Zepeda, J. MacLean, I. Charo, and A. Luster. 1997. Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. J. Exp. Med. 185:99-110.
20. Takeda, K., E. Hamelmann, A. Joetham, L. D. Shultz, G. L. Larsen, C. G. Irvin, and E. W. Gelfand. 1997. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast-cell-deficient mice. J. Exp. Med. 186:449-454.
21. Mehlop, P., M. van de Rijn, A. Goldberg, J. Brewer, V. Kurup, T. Martin, and H. Oettgen. 1997. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc. Natl. Acad. Sci. USA 94:1344-1349.
22. Kung, T., D. Stelts, J. Zurcher, H. Jones, S. Umland, R. Kreutne, R. Egan, and R. Chapman. 1995. Mast cells modulate allergic pulmonary eosinophilia in mice. Am. J. Respir. Cell Mol. Biol. 12:404-409.
23. Galli, S. J. 1997. Complexity and redundancy in the pathogenesis of asthma: reassessing the roles of mast cells and T cells. J. Exp. Med. 186:343-347.
24. De Sanctis, G., W. Wolyniec, F. Green, S. Qin, A. Jiao, P. Finn, T. Noonan, A. Joetham, E. Gelfand, C. Dofrschuk, and J. Drazen. 1997. Reduction of allergic airway responses in P-selectin-deficient mice. J. Appl. Physiol. 83: 681-687.
25. De Sanctis, G. T., A. Itoh, F. H. Y. Green, S. Qin, T. Kimura, J. K. Grobholz, T. R. Martin, T. Maki, and J. M. Drazen. 1997. T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice. Nat. Med. 3:460-462.
26. Larsen, G. L., H. Renz, J. E. Loader, K. L. Bradley, and E. W. Gelfand. 1992. Airway response to electrical field stimulation in sensitized inbred mice: passive transfer of increased responsiveness with peribronchial lymph nodes. J. Clin. Invest. 89:747-752.
27. Drazen, J., J. Arm, and K. Austen. 1996. Sorting out the cytokines in asthma. J. Exp. Med. 183:1-5.
28. Martin, T., T. Takeishi, H. Katz, K. Austen, J. Drazen, and S. Galli. 1993. Mast cell activation enhances airway responsiveness to methacholine in the mouse. J. Clin. Invest. 91:1176-1182.
29. Hogan, S. P., A. Mould, H. Kikutani, A. J. Ramsay, and A. J. Foster. 1997. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest. 99:1329-1339.
30. Garssen, J. G., F. P. Nijkamp, H. Van Der Vliet, and H. Van Loveren. 1991. T cell mediated induction of airway hyperreactivity in mice. Am. Rev. Respir. Dis. 144:931-938.
31. Griffiths-Johnson, D., P. Collins, A. Rossi, P. Jose, and T. Williams. 1993. The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo. Biochem. Biophys. Res. Commun. 197:1167-1172.
32. Rothenberg, M. E., A. D. Luster, C. M. Lilly, J. M. Drazen, and P. Leder. 1995. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J. Exp. Med. 181:1211-1216.
33. Gonzalo, J.-A., C. Lloyd, L. Kremer, E. Finger, C. Martinez, M. Siegelman, M. Cybulsky, and J. Gutierrez-Ramos. 1996. Eosinophil recruitment to the lung in a murine model of allergic inflammation: the role of T cells, chemokines and adhesion receptors. J. Clin. Invest. 98:2332-2345.
34. Gonzalo, J., G. Jia, V. Aguirre, D. Friend, A. Coyle, N. Jenkins, G. Lin, H. Katz, A. Lichtman, N. Copeland, M. Kopf, and J. Gutierrez-Ramos. 1996. Mouse eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response. Immunity 4:1-14.
35. Lukacs, N., R. Strieter, S. Chensue, and S. Kunkel. 1996. Activation and regulation of chemokines in allergic airway inflammation. J. Leukoc. Biol. 59:13-17.
36. Krzesicki, R. F., G. E. Winterrowd, J. R. Brashler, C. A. Hatfield, R. L. Griffin, S. F. Fidler, K. P. Kolbasa, K. L. Shull, I. M. Richards, and J. E. Chin. 1997. Identification of cytokine and adhesion molecule mRNA in murine lung tissue and isolated T cells and eosinophils by semi-quantitative reverse transcriptase-polymerase chain reaction. Am. J. Respir. Cell Mol. Biol. 16:693-701.
37. Humbles, A. A., D. M. Conroy, S. Marleau, S. M. Rankin, R. T. Palframan, A. E. Proudfoot, T. N. Wells, D. Li, P. K. Jeffery, D. A. Griffiths-Johnson, T. J. Williams, and P. J. Jose. 1997. Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo. J. Exp. Med. 186:601-612.
38. Rothenberg, M. E., J. A. MacLean, E. Pearlman, A. D. Luster, and P. Leder, 1997. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. J. Exp. Med. 185:785-790.
39. Stafford, S., H. Li, P. Forsythe, M. Ryan, R. Bravo, and R. Alam. 1997. Monocyte chemotactic protein-3 (MCP-3)/fibroblast-induced cytokine (FIC) in eosinophilic inflammation of the airways and the inhibitory effects of an anti-MCP-3/FIC antibody. J. Immunol. 158:4953-4960.