메뉴 건너뛰기




Volumn 185, Issue 12, 1997, Pages 2143-2156

Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 5;

EID: 17444454662     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.12.2143     Document Type: Article
Times cited : (483)

References (51)
  • 1
    • 0023846386 scopus 로고
    • Allergen-induced airway hyperresponsiveness
    • O'Byrne, P.M. 1988. Allergen-induced airway hyperresponsiveness. J. Allergy Clin. Immunol. 81:119-127.
    • (1988) J. Allergy Clin. Immunol. , vol.81 , pp. 119-127
    • O'Byrne, P.M.1
  • 2
    • 0017229586 scopus 로고
    • Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection
    • Empey, D.W., L.A. Laitinen, L. Jacobs, W.M. Gold, and J.A. Nadel. 1976. Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am. Rev. Resp. Dis. 113:131-139.
    • (1976) Am. Rev. Resp. Dis. , vol.113 , pp. 131-139
    • Empey, D.W.1    Laitinen, L.A.2    Jacobs, L.3    Gold, W.M.4    Nadel, J.A.5
  • 5
    • 0028223206 scopus 로고
    • Role of leukotrienes in asthma
    • Henderson, W., Jr. 1994. Role of leukotrienes in asthma. Ann. Allergy 72:272-278.
    • (1994) Ann. Allergy , vol.72 , pp. 272-278
    • Henderson Jr., W.1
  • 6
    • 0028043432 scopus 로고
    • Comparison of the immunopathology of extrinsic, intrinsic and occupational asthma
    • Bentley, A.M., S.R. Durham, and A.B. Kay. 1994. Comparison of the immunopathology of extrinsic, intrinsic and occupational asthma. J. Invest. Allergol. Clin. Immunol. 4:222-232.
    • (1994) J. Invest. Allergol. Clin. Immunol. , vol.4 , pp. 222-232
    • Bentley, A.M.1    Durham, S.R.2    Kay, A.B.3
  • 12
    • 0028455633 scopus 로고
    • Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
    • Gavett, S.H., X. Chen, F. Finkelman, and M. Wills-Karp. 1994. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Resp. Cell Mol. Biol. 10:587-593.
    • (1994) Am. J. Resp. Cell Mol. Biol. , vol.10 , pp. 587-593
    • Gavett, S.H.1    Chen, X.2    Finkelman, F.3    Wills-Karp, M.4
  • 13
    • 0026683014 scopus 로고
    • CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea
    • Nakajima, H., I. Iwamoto, S. Tomoe, R. Matsumura, H. Tomioka, K. Takatsu, and S. Yoshida. 1992. CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Resp. Dis. 146:374-377.
    • (1992) Am. Rev. Resp. Dis. , vol.146 , pp. 374-377
    • Nakajima, H.1    Iwamoto, I.2    Tomoe, S.3    Matsumura, R.4    Tomioka, H.5    Takatsu, K.6    Yoshida, S.7
  • 14
    • 0029862948 scopus 로고    scopus 로고
    • Requirement for CD8(+) T cells in the development of airway hyperresponsiveness in a murine model of airway sensitization
    • Hamelmann, E., A. Oshiba, J. Paluh, K. Bradley, J. Loader, T.A. Potter, G.L. Larsen, and E.W. Gelfand. 1996. Requirement for CD8(+) T cells in the development of airway hyperresponsiveness in a murine model of airway sensitization. J. Exp. Med. 183:1719-1729.
    • (1996) J. Exp. Med. , vol.183 , pp. 1719-1729
    • Hamelmann, E.1    Oshiba, A.2    Paluh, J.3    Bradley, K.4    Loader, J.5    Potter, T.A.6    Larsen, G.L.7    Gelfand, E.W.8
  • 16
    • 0029266795 scopus 로고
    • Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice
    • Brusselle, G., J. Kips, G. Joos, H. Bluethmann, and R. Pauwels. 1995. Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am. J. Resp. Cell Mol. Biol. 12:254-259.
    • (1995) Am. J. Resp. Cell Mol. Biol. , vol.12 , pp. 254-259
    • Brusselle, G.1    Kips, J.2    Joos, G.3    Bluethmann, H.4    Pauwels, R.5
  • 17
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster, P.S., S.P. Hogan, A.J. Ramsay, K.I. Matthaei, and I.G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195-201.
    • (1996) J. Exp. Med. , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 18
    • 0025083185 scopus 로고
    • IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice
    • Tepper, R.I., D.A. Levinson, B.Z. Stanger, J. Campos-Torres, A.K. Abbas, and P. Leder. 1990. IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice. Cell. 62:457-467.
    • (1990) Cell , vol.62 , pp. 457-467
    • Tepper, R.I.1    Levinson, D.A.2    Stanger, B.Z.3    Campos-Torres, J.4    Abbas, A.K.5    Leder, P.6
  • 20
    • 0029053613 scopus 로고
    • Impaired survival of T cell receptor V gamma 3+ cells in interleukin-4 transgenic mice
    • Erb, K.J., T. Hanke, A. Schimpl, T. Hunig, G. Stingl, and A. Elbe. 1995. Impaired survival of T cell receptor V gamma 3+ cells in interleukin-4 transgenic mice. Eur. J. Immunol. 25: 1442-1445.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1442-1445
    • Erb, K.J.1    Hanke, T.2    Schimpl, A.3    Hunig, T.4    Stingl, G.5    Elbe, A.6
  • 21
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung - lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • Rankin, J.A., D.E. Picarella, G.P. Geba, U.A. Temann, B. Prasad, B. Dicosmo, A. Tarallo, B. Stripp, J. Whitsett, and R.A. Flavell. 1996. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung - lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc. Natl. Acad. Sci. USA. 93:7821-7825.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7821-7825
    • Rankin, J.A.1    Picarella, D.E.2    Geba, G.P.3    Temann, U.A.4    Prasad, B.5    Dicosmo, B.6    Tarallo, A.7    Stripp, B.8    Whitsett, J.9    Flavell, R.A.10
  • 22
    • 0031068013 scopus 로고    scopus 로고
    • Expression of Il-5 in thymocytes T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies
    • Lee, N.A., M.P. McGarry, K.A. Larson, M.A. Horton, A.B. Kristensen, and J.J. Lee. 1997. Expression of Il-5 in thymocytes T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies. J. Immunol. 158:1332-1344.
    • (1997) J. Immunol. , vol.158 , pp. 1332-1344
    • Lee, N.A.1    McGarry, M.P.2    Larson, K.A.3    Horton, M.A.4    Kristensen, A.B.5    Lee, J.J.6
  • 23
    • 0025036906 scopus 로고
    • Eosinophilia in transgenic mice expressing interleukin 5
    • Dent, L.A., M. Strath, A.L. Mellor, and C.J. Sanderson. 1990. Eosinophilia in transgenic mice expressing interleukin 5. J. Exp. Med. 172:1425-1431.
    • (1990) J. Exp. Med. , vol.172 , pp. 1425-1431
    • Dent, L.A.1    Strath, M.2    Mellor, A.L.3    Sanderson, C.J.4
  • 24
    • 0026016424 scopus 로고
    • Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production
    • Tominaga, A., S. Takaki, N. Koyama, S. Katoh, R. Matsumoto, M. Migita, Y. Hitoshi, Y. Hosoya, S. Yamauchi, Y. Kanai et al. 1991. Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production. J. Exp. Med. 173: 429-437.
    • (1991) J. Exp. Med. , vol.173 , pp. 429-437
    • Tominaga, A.1    Takaki, S.2    Koyama, N.3    Katoh, S.4    Matsumoto, R.5    Migita, M.6    Hitoshi, Y.7    Hosoya, Y.8    Yamauchi, S.9    Kanai, Y.10
  • 25
    • 0029081157 scopus 로고
    • Evaluation of airway hyperreactivity in interleukin-5 transgenic mice
    • Iwamoto, T., and K. Takatsu. 1995. Evaluation of airway hyperreactivity in interleukin-5 transgenic mice. Int. Arch. Allergy Immunol. 1:28-30.
    • (1995) Int. Arch. Allergy Immunol. , vol.1 , pp. 28-30
    • Iwamoto, T.1    Takatsu, K.2
  • 26
    • 0029992156 scopus 로고    scopus 로고
    • Identification of IL-5 and RANTES as the major eosinophil chemoattractants in the asthmatic lung
    • Venge, J., M. Lampinen, L. Hakansson, S. Rak, and P. Venge. 1996. Identification of IL-5 and RANTES as the major eosinophil chemoattractants in the asthmatic lung. J. Allergy Clin. Immunol. 97:1110-1115.
    • (1996) J. Allergy Clin. Immunol. , vol.97 , pp. 1110-1115
    • Venge, J.1    Lampinen, M.2    Hakansson, L.3    Rak, S.4    Venge, P.5
  • 27
    • 0026738951 scopus 로고
    • Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice
    • Hackett, B.P., and J.D. Gitlin. 1992. Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice. Proc. Natl. Acad. Sci. USA. 89:9079-9083.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9079-9083
    • Hackett, B.P.1    Gitlin, J.D.2
  • 28
    • 0029760357 scopus 로고    scopus 로고
    • Cloning of the murine eosinophil peroxidase gene (mEPO): Characterization of a conserved subgroup of mammalian hematopoietic peroxidases
    • Horton, M.A., K.A. Larson, J.J. Lee, and N.A. Lee. 1996. Cloning of the murine eosinophil peroxidase gene (mEPO): characterization of a conserved subgroup of mammalian hematopoietic peroxidases. J. Leukoc. Biol. 60:285-294.
    • (1996) J. Leukoc. Biol. , vol.60 , pp. 285-294
    • Horton, M.A.1    Larson, K.A.2    Lee, J.J.3    Lee, N.A.4
  • 29
    • 0026703747 scopus 로고
    • Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine Hβ58 embryonic lethal transgene insertion
    • Lee, J.J., G. Radice, C.P. Perkins, and F.D. Costantini. 1992. Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine Hβ58 embryonic lethal transgene insertion. Development. 115:277-288.
    • (1992) Development , vol.115 , pp. 277-288
    • Lee, J.J.1    Radice, G.2    Perkins, C.P.3    Costantini, F.D.4
  • 30
    • 0026719193 scopus 로고
    • Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse
    • Renz, H., H.R. Smith, J.E. Henson, B.S. Ray, C.G. Irvin, and E.W. Gelfand. 1992. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J. Allergy Clin. Immunol. 89:1127-1138.
    • (1992) J. Allergy Clin. Immunol. , vol.89 , pp. 1127-1138
    • Renz, H.1    Smith, H.R.2    Henson, J.E.3    Ray, B.S.4    Irvin, C.G.5    Gelfand, E.W.6
  • 31
    • 26344463340 scopus 로고    scopus 로고
    • Measurement of airway hyperresponsiveness (AHR) to inhaled methacholine in free-running allergen-sensitized mice
    • Hamelmann, E., J. Shwarze, K. Takeda, A. Oshiba, and E.W. Gelfand. 1996. Measurement of airway hyperresponsiveness (AHR) to inhaled methacholine in free-running allergen-sensitized mice. Am. J. Resp. Crit. Care Med. 153:A625.
    • (1996) Am. J. Resp. Crit. Care Med. , vol.153
    • Hamelmann, E.1    Shwarze, J.2    Takeda, K.3    Oshiba, A.4    Gelfand, E.W.5
  • 32
    • 0026674820 scopus 로고
    • The regulated expression of mRNA for Clara cell protein in the developing airways of the rat, as revealed by tissue in situ hybridization
    • Strum, J.M., R.S. Compton, S.L. Katyal, and G. Singh. 1992. The regulated expression of mRNA for Clara cell protein in the developing airways of the rat, as revealed by tissue in situ hybridization. Tissue Cell. 24:461-471.
    • (1992) Tissue Cell , vol.24 , pp. 461-471
    • Strum, J.M.1    Compton, R.S.2    Katyal, S.L.3    Singh, G.4
  • 33
    • 0021985768 scopus 로고
    • Bronchus-associated lymphoid tissue
    • Bienenstock, J. 1985. Bronchus-associated lymphoid tissue. Int. Arch. Allergy Appl. Immunol. 76(suppl. 1):62-69.
    • (1985) Int. Arch. Allergy Appl. Immunol. , vol.76 , Issue.1 SUPPL. , pp. 62-69
    • Bienenstock, J.1
  • 34
    • 0029056336 scopus 로고
    • The identification and cloning of a murine major basic protein gene expressed in eosinophils
    • Larson, K., M. Horton, B. Madden, G. Gleich, N. Lee, and J. Lee. 1995. The identification and cloning of a murine major basic protein gene expressed in eosinophils. J. Immunol. 155: 3002-3012.
    • (1995) J. Immunol. , vol.155 , pp. 3002-3012
    • Larson, K.1    Horton, M.2    Madden, B.3    Gleich, G.4    Lee, N.5    Lee, J.6
  • 35
    • 0023831561 scopus 로고
    • Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma-relationship to bronchial hyperreactivity
    • Wardlaw, A.J., S. Dunnette, G.J. Gleich, J.V. Collins, and A.B. Kay. 1988. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma-relationship to bronchial hyperreactivity. Am. Rev. Respir. Dis. 137:62-69.
    • (1988) Am. Rev. Respir. Dis. , vol.137 , pp. 62-69
    • Wardlaw, A.J.1    Dunnette, S.2    Gleich, G.J.3    Collins, J.V.4    Kay, A.B.5
  • 36
    • 0030068041 scopus 로고    scopus 로고
    • Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites
    • Li, J., R. Cook, K. Dede, and I. Chaiken. 1996. Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites. J. Biol. Chem. 271:1817-1820.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1817-1820
    • Li, J.1    Cook, R.2    Dede, K.3    Chaiken, I.4
  • 37
    • 0025469569 scopus 로고
    • Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans?
    • Pabst, R., and I. Gehrke. 1990. Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans? Am. J. Resp. Cell Mol. Biol. 3:131-135.
    • (1990) Am. J. Resp. Cell Mol. Biol. , vol.3 , pp. 131-135
    • Pabst, R.1    Gehrke, I.2
  • 38
    • 0021813331 scopus 로고
    • BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12)
    • Harada, N., Y. Kikuchi, A. Tominaga, S. Takaki, and K. Takatsu. 1985. BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12). J. Immunol. 134:3944-3951.
    • (1985) J. Immunol. , vol.134 , pp. 3944-3951
    • Harada, N.1    Kikuchi, Y.2    Tominaga, A.3    Takaki, S.4    Takatsu, K.5
  • 39
  • 40
    • 0029984040 scopus 로고    scopus 로고
    • Eosinophil recruitment is associated with IL-5, but not with RANTES, twenty-four hours after allergen challenge
    • Sur, S., H. Kita, G.J. Gleich, T.C. Chenier, and L.W. Hunt. 1996. Eosinophil recruitment is associated with IL-5, but not with RANTES, twenty-four hours after allergen challenge. J. Allergy Clin. Immunol. 97:1272-1278.
    • (1996) J. Allergy Clin. Immunol. , vol.97 , pp. 1272-1278
    • Sur, S.1    Kita, H.2    Gleich, G.J.3    Chenier, T.C.4    Hunt, L.W.5
  • 41
    • 0028053993 scopus 로고
    • IgE and eosinophil regulation in a murine model of allergic aspergillosis
    • Kurup, V.P., H. Choi, P.S. Murali, and R.L. Coffman. 1994. IgE and eosinophil regulation in a murine model of allergic aspergillosis. J. Leukoc. Biol. 56:593-598.
    • (1994) J. Leukoc. Biol. , vol.56 , pp. 593-598
    • Kurup, V.P.1    Choi, H.2    Murali, P.S.3    Coffman, R.L.4
  • 42
    • 0028929545 scopus 로고
    • Virus-specific CD8+ cells can switch to interleukin 5 production and induce airway eosinophilia
    • Coyle, A.J., F. Erard, C. Bertrand, S. Walti, H. Pircher, and G. Le Gros. 1995. Virus-specific CD8+ cells can switch to interleukin 5 production and induce airway eosinophilia. J. Exp. Med. 181:1229-1233.
    • (1995) J. Exp. Med. , vol.181 , pp. 1229-1233
    • Coyle, A.J.1    Erard, F.2    Bertrand, C.3    Walti, S.4    Pircher, H.5    Le Gros, G.6
  • 44
    • 0027164805 scopus 로고
    • Effect of anti-IL-5 monoclonal antibody on allergic bronchial eosinophilia and airway hyperresponsiveness in mice
    • Nagai, H., S. Yamaguchi, N. Inagaki, N. Tsuruoka, Y. Hitoshi, and K. Takatsu. 1993. Effect of anti-IL-5 monoclonal antibody on allergic bronchial eosinophilia and airway hyperresponsiveness in mice. Life Sciences. 53:L243-247.
    • (1993) Life Sciences , vol.53
    • Nagai, H.1    Yamaguchi, S.2    Inagaki, N.3    Tsuruoka, N.4    Hitoshi, Y.5    Takatsu, K.6
  • 45
  • 47
    • 0029969336 scopus 로고    scopus 로고
    • Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness
    • Lefort, J., C.M. Bachelet, D. Leduc, and B.B. Vargaftig. 1996. Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness. J. Allergy Clin. Immunol. 97:788-799.
    • (1996) J. Allergy Clin. Immunol. , vol.97 , pp. 788-799
    • Lefort, J.1    Bachelet, C.M.2    Leduc, D.3    Vargaftig, B.B.4
  • 49
    • 0029148025 scopus 로고
    • Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
    • Collins, P.D., S. Marleau, D.A. Griffiths-Johnson, P.J. Jose, and T.J. Williams. 1995. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J. Exp. Med. 182:1169-1174.
    • (1995) J. Exp. Med. , vol.182 , pp. 1169-1174
    • Collins, P.D.1    Marleau, S.2    Griffiths-Johnson, D.A.3    Jose, P.J.4    Williams, T.J.5
  • 50
    • 0029558250 scopus 로고
    • Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness
    • Eum, S.Y., S. Haile, J. Lefort, M. Huerre, and B.B. Vargaftig. 1995. Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness. Proc. Natl. Acad. Sci. USA. 92:12290-12294.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12290-12294
    • Eum, S.Y.1    Haile, S.2    Lefort, J.3    Huerre, M.4    Vargaftig, B.B.5
  • 51
    • 0029826972 scopus 로고    scopus 로고
    • Schistosoma mansom egg-induced early IL-4 production is dependent upon IL-5 and eosinophils
    • Sabin, E.A., M.A. Kopf, and E.J. Pearce. 1996. Schistosoma mansom egg-induced early IL-4 production is dependent upon IL-5 and eosinophils. J. Exp. Med. 184:1871-1878.
    • (1996) J. Exp. Med. , vol.184 , pp. 1871-1878
    • Sabin, E.A.1    Kopf, M.A.2    Pearce, E.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.