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Volumn 101, Issue 10, 1998, Pages 2129-2139

Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma

Author keywords

Adhesion molecules; Airway inflammation; Human lung fibroblasts; Proinflammatory cytokines; Signal transduction

Indexed keywords

CYCLOHEXIMIDE; INTEGRIN; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULAR CELL ADHESION MOLECULE 1;

EID: 0032523927     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI741     Document Type: Article
Times cited : (329)

References (52)
  • 1
    • 0024505353 scopus 로고
    • Subepithelial fibrosis in the bronchi of asthmatics
    • Roche, W.R., R. Beasley, J.H. Williams, and S.T. Holgate. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet. 1:520-523.
    • (1989) Lancet , vol.1 , pp. 520-523
    • Roche, W.R.1    Beasley, R.2    Williams, J.H.3    Holgate, S.T.4
  • 5
    • 0028144783 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma
    • Woodley, K.L., E. Adelroth, M.J. Woolley, R. Ellis, M. Jordana, and P.M. O'Byrne. 1994. Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. Eur. Resp. J. 7:1576-1584.
    • (1994) Eur. Resp. J. , vol.7 , pp. 1576-1584
    • Woodley, K.L.1    Adelroth, E.2    Woolley, M.J.3    Ellis, R.4    Jordana, M.5    O'Byrne, P.M.6
  • 6
  • 7
    • 0026761470 scopus 로고
    • Collagen and fibronectin production by Thy 1+ and Thy 1- lung fibroblast subpopulations
    • Derdak, S., D.P. Penney, P. Keng, M. Felch, D. Brown, and R.P. Phipps. 1992. Collagen and fibronectin production by Thy 1+ and Thy 1-lung fibroblast subpopulations. Am. J. Physiol. 263:L283-L290.
    • (1992) Am. J. Physiol. , vol.263
    • Derdak, S.1    Penney, D.P.2    Keng, P.3    Felch, M.4    Brown, D.5    Phipps, R.P.6
  • 8
    • 0026446005 scopus 로고
    • Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4
    • Postlethwaite, A.E., M.A. Holness, H. Katai, and R. Raghow. 1992. Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4. J. Clin. Invest. 90:1479-1485.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1479-1485
    • Postlethwaite, A.E.1    Holness, M.A.2    Katai, H.3    Raghow, R.4
  • 10
    • 0028122690 scopus 로고
    • Heterogeneity of myofibroblast phenotypic features: An example of fibroblastic cell plasticity
    • Schmitt-Gräff, A., A. Desmoulière, and G. Gabbiani. 1994. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch. 425:3-24.
    • (1994) Virchows Arch. , vol.425 , pp. 3-24
    • Schmitt-Gräff, A.1    Desmoulière, A.2    Gabbiani, G.3
  • 11
    • 0024690462 scopus 로고
    • Characterization of two major populations of lung fibroblasts: Distinguishing morphology and discordant display of Thy 1 and class II MHC
    • Phipps, R.P., D.P. Penney, P. Keng, H. Quill, A. Paxhia, S. Derdak, and M.E. Felch. 1989. Characterization of two major populations of lung fibroblasts: distinguishing morphology and discordant display of Thy 1 and class II MHC. Am. J. Respir. Cell Mol. Biol. 1:65-74.
    • (1989) Am. J. Respir. Cell Mol. Biol. , vol.1 , pp. 65-74
    • Phipps, R.P.1    Penney, D.P.2    Keng, P.3    Quill, H.4    Paxhia, A.5    Derdak, S.6    Felch, M.E.7
  • 13
    • 0027257928 scopus 로고
    • The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of p64/IL-2R gamma chain
    • Plaisance, S., E. Rubinstein, A. Alileche, P. Benoit, C. Jasmin, and B. Azzarone. 1993. The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of p64/IL-2R gamma chain. Int. Immunol. 5:843-848.
    • (1993) Int. Immunol. , vol.5 , pp. 843-848
    • Plaisance, S.1    Rubinstein, E.2    Alileche, A.3    Benoit, P.4    Jasmin, C.5    Azzarone, B.6
  • 14
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
    • Kondo, M., T. Takeshita, N. Ishii, M. Nakamura, S. Watanabe, K. Arai, and K. Sugamura. 1993. Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science. 262:1874-1877.
    • (1993) Science , vol.262 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3    Nakamura, M.4    Watanabe, S.5    Arai, K.6    Sugamura, K.7
  • 19
    • 0028917463 scopus 로고
    • Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukin 2, 4, 7, 9, and 15
    • Obiri, N.I., W. Debinsky, W.J. Leonard, and R.K. Puri. 1995. Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukin 2, 4, 7, 9, and 15. J. Biol. Chem. 270:8797-8804.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8797-8804
    • Obiri, N.I.1    Debinsky, W.2    Leonard, W.J.3    Puri, R.K.4
  • 20
    • 0028898492 scopus 로고
    • Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types
    • Vita, N., S. Lefort, P. Laurent, D. Caput, and P. Ferrara. 1995. Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types. J. Biol. Chem. 270:3512-3517.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3512-3517
    • Vita, N.1    Lefort, S.2    Laurent, P.3    Caput, D.4    Ferrara, P.5
  • 21
    • 0028176655 scopus 로고
    • Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells
    • Zurawski, G., and J.E. de Vries. 1994. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol. Today. 15:19-26.
    • (1994) Immunol. Today , vol.15 , pp. 19-26
    • Zurawski, G.1    De Vries, J.E.2
  • 22
    • 0025050820 scopus 로고
    • Differentiation repertoire of fibroblastic cells. Expression of cytoskeletal proteins as markers of phenotypic modulations
    • Sappino, A.P., W. Schürch, and G. Gabbiani. 1990. Differentiation repertoire of fibroblastic cells. Expression of cytoskeletal proteins as markers of phenotypic modulations. Lab. Invest. 63:144-161.
    • (1990) Lab. Invest. , vol.63 , pp. 144-161
    • Sappino, A.P.1    Schürch, W.2    Gabbiani, G.3
  • 25
    • 0030456345 scopus 로고    scopus 로고
    • Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge
    • Chvatchko, Y., M.H. Kosco-Vilbois, S. Herren, J. Lefort, and J.-Y. Bonnefoy. 1996. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J. Exp. Med. 184: 2353-2360.
    • (1996) J. Exp. Med. , vol.184 , pp. 2353-2360
    • Chvatchko, Y.1    Kosco-Vilbois, M.H.2    Herren, S.3    Lefort, J.4    Bonnefoy, J.-Y.5
  • 27
    • 0021324498 scopus 로고
    • 4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not adult origin
    • Azzarone, B., H. Suarez, M. Mingari, L. Moretta, and A.S. Fauci. 1984. 4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not adult origin. J. Cell Biol. 98:1133-1137.
    • (1984) J. Cell Biol. , vol.98 , pp. 1133-1137
    • Azzarone, B.1    Suarez, H.2    Mingari, M.3    Moretta, L.4    Fauci, A.S.5
  • 30
    • 0025310391 scopus 로고
    • Putative γ-subunit of the IL-2 receptor is detected in low, intermediate, and high affinity IL-2 receptor-bearing cells
    • Colamonici, O.R., L.M. Neckers, and A. Rosolen. 1990. Putative γ-subunit of the IL-2 receptor is detected in low, intermediate, and high affinity IL-2 receptor-bearing cells. J. Immunol. 145:155-160.
    • (1990) J. Immunol. , vol.145 , pp. 155-160
    • Colamonici, O.R.1    Neckers, L.M.2    Rosolen, A.3
  • 31
    • 0029054073 scopus 로고
    • IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells
    • Lefort, S., N. Vita, R. Reeb, D. Caput, and P. Ferrara. 1995. IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells. FEBS (Fed. Eur. Biochem. Soc.) Lett. 366:122-126.
    • (1995) FEBS (Fed. Eur. Biochem. Soc.) Lett. , vol.366 , pp. 122-126
    • Lefort, S.1    Vita, N.2    Reeb, R.3    Caput, D.4    Ferrara, P.5
  • 33
    • 0028209970 scopus 로고
    • Regulation by interleukin-2 (IL-2) and interferon γ of IL-2 receptor γ chain gene expression in human monocytes
    • Bosco, M.C., I. Espinoza-Delgado, M. Schwabe, G.L. Gusella, D.L. Longo, K. Sugamura, and L. Varesio. 1994. Regulation by interleukin-2 (IL-2) and interferon γ of IL-2 receptor γ chain gene expression in human monocytes. Blood. 83:2995-3002.
    • (1994) Blood , vol.83 , pp. 2995-3002
    • Bosco, M.C.1    Espinoza-Delgado, I.2    Schwabe, M.3    Gusella, G.L.4    Longo, D.L.5    Sugamura, K.6    Varesio, L.7
  • 35
    • 0028129414 scopus 로고
    • Regulation of endothelial and mesothelial cell function by interleukin-13: Selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production
    • Sironi, M., F.L. Sciacca, C. Matteucci, M. Conni, A. Vecchi, S. Bernasconi, A. Minty, D. Caput, P. Ferrara, and F. Colotta. 1994. Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood. 84:1913-1921.
    • (1994) Blood , vol.84 , pp. 1913-1921
    • Sironi, M.1    Sciacca, F.L.2    Matteucci, C.3    Conni, M.4    Vecchi, A.5    Bernasconi, S.6    Minty, A.7    Caput, D.8    Ferrara, P.9    Colotta, F.10
  • 36
    • 0028815074 scopus 로고
    • IL-13 selectively induces vascular cell adhesion molecule-1 expression on human endothelial cells
    • Bochner, B.S., D.A. Klunk, S.A. Sterbinsky, R.L. Coffman, and R.P. Schleimer. 1995. IL-13 selectively induces vascular cell adhesion molecule-1 expression on human endothelial cells. J. Immunol. 154:799-803.
    • (1995) J. Immunol. , vol.154 , pp. 799-803
    • Bochner, B.S.1    Klunk, D.A.2    Sterbinsky, S.A.3    Coffman, R.L.4    Schleimer, R.P.5
  • 37
    • 0025020024 scopus 로고
    • Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma
    • Wegner, C.D., R.H. Gundel, P. Reilly, N. Haynes, L.G. Letts, and R. Rothlein. 1990. Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. Science. 247:456-459.
    • (1990) Science , vol.247 , pp. 456-459
    • Wegner, C.D.1    Gundel, R.H.2    Reilly, P.3    Haynes, N.4    Letts, L.G.5    Rothlein, R.6
  • 38
    • 0030739790 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 on cultured human epithelial cell lines: Influence of proinflammatory cytokines
    • Paolieri, F., M. Battifora, A.M. Riccio, G. Pesce, G.W. Canonica, and M. Bagnasco. 1997. Intercellular adhesion molecule-1 on cultured human epithelial cell lines: influence of proinflammatory cytokines. Allergy. 52:521-531.
    • (1997) Allergy , vol.52 , pp. 521-531
    • Paolieri, F.1    Battifora, M.2    Riccio, A.M.3    Pesce, G.4    Canonica, G.W.5    Bagnasco, M.6
  • 39
    • 0028013275 scopus 로고
    • Myofibroblast and concurrent ED-B fibronectin phenotype in human stromal cells cultured from non-malignant and malignant breast tissue
    • Brouty-Boyé, D., and V. Magnien. 1994. Myofibroblast and concurrent ED-B fibronectin phenotype in human stromal cells cultured from non-malignant and malignant breast tissue. Eur. J. Cancer. 30A:66-73.
    • (1994) Eur. J. Cancer. , vol.30 A , pp. 66-73
    • Brouty-Boyé, D.1    Magnien, V.2
  • 40
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
    • Hilton, D.G., J.-G. Zhang, D. Metcalf, W.S. Alexander, N.A. Nicola, and T.A. Willson. 1996. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. USA. 93:497-501.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 497-501
    • Hilton, D.G.1    Zhang, J.-G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Willson, T.A.6
  • 41
    • 0027274890 scopus 로고
    • Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
    • Zurawski, S.M., F.J. Vega, B. Huyghe, and G. Zurawski. 1993. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO (Eur. Mol. Biol. Organ.) J. 12:2663-2670.
    • (1993) EMBO (Eur. Mol. Biol. Organ.) J. , vol.12 , pp. 2663-2670
    • Zurawski, S.M.1    Vega, F.J.2    Huyghe, B.3    Zurawski, G.4
  • 42
    • 10544246077 scopus 로고    scopus 로고
    • cDNA cloning and characterization of the human interleukin 13 receptor α chain
    • Aman, M.J., N. Tayebi, N.I. Obiri, R.K. Puri, W.S. Modi, and W.J. Leonard. 1996. cDNA cloning and characterization of the human interleukin 13 receptor α chain. J. Biol. Chem. 271:29265-29270.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29265-29270
    • Aman, M.J.1    Tayebi, N.2    Obiri, N.I.3    Puri, R.K.4    Modi, W.S.5    Leonard, W.J.6
  • 43
    • 0029927153 scopus 로고    scopus 로고
    • Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain
    • Caput, D., P. Laurent, M. Kaghad, J.-M. Lelias, S. Lefort, N. Vita, and P. Ferrara. 1996. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain. J. Biol. Chem. 271:16921-16926.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16921-16926
    • Caput, D.1    Laurent, P.2    Kaghad, M.3    Lelias, J.-M.4    Lefort, S.5    Vita, N.6    Ferrara, P.7
  • 45
    • 0029834119 scopus 로고    scopus 로고
    • Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor α subunit
    • Lai, S.Y., J. Molden, K.D. Liu, J.M. Puck, M.D. White, and M.A. Goldsmith. 1996. Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor α subunit. EMBO (Eur. Mol. Biol. Organ.) J. 15:4506-4514.
    • (1996) EMBO (Eur. Mol. Biol. Organ.) J. , vol.15 , pp. 4506-4514
    • Lai, S.Y.1    Molden, J.2    Liu, K.D.3    Puck, J.M.4    White, M.D.5    Goldsmith, M.A.6
  • 46
    • 0031570471 scopus 로고    scopus 로고
    • The IL-4 receptor α-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression
    • Reichel, M., B.H. Nelson, P.D. Greenberg, and P. Rothman. 1997. The IL-4 receptor α-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression. J. Immunol. 158:5860-5867.
    • (1997) J. Immunol. , vol.158 , pp. 5860-5867
    • Reichel, M.1    Nelson, B.H.2    Greenberg, P.D.3    Rothman, P.4
  • 47
    • 0029855722 scopus 로고    scopus 로고
    • Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-γ and interleukin-4 receptor-α
    • Malabarba, M.G., H. Rui, H.H. Deutsch, J. Chung, F.S. Kalthoff, W.L. Farrar, and R.A. Kirken. 1996. Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-γ and interleukin-4 receptor-α. Biochem. J. 319:865-872.
    • (1996) Biochem. J. , vol.319 , pp. 865-872
    • Malabarba, M.G.1    Rui, H.2    Deutsch, H.H.3    Chung, J.4    Kalthoff, F.S.5    Farrar, W.L.6    Kirken, R.A.7
  • 49
    • 0029763527 scopus 로고    scopus 로고
    • Role of integrins in regulation of collagen phagocytosis by human fibroblasts
    • Lee, W., J. Sodek, and C.A.G. McCulloch. 1996. Role of integrins in regulation of collagen phagocytosis by human fibroblasts. J. Cell. Physiol. 168: 695-704.
    • (1996) J. Cell. Physiol. , vol.168 , pp. 695-704
    • Lee, W.1    Sodek, J.2    McCulloch, C.A.G.3
  • 50
    • 0029739012 scopus 로고    scopus 로고
    • Function at the junction: Dynamic interactions between lung cells and extracellular matrix
    • Spurzem, J.R. 1996. Function at the junction: dynamic interactions between lung cells and extracellular matrix. Thorax. 51:956-958.
    • (1996) Thorax , vol.51 , pp. 956-958
    • Spurzem, J.R.1
  • 51
    • 0028785274 scopus 로고
    • Effects of T-helper 2-type cytokines, interleukin-3 (IL-3), IL-4, IL-5, and IL-6 on the survival of cultured human mast cells
    • Yanagida, M., H. Fukamachi, K. Ohgami, T. Kuwaki, H. Ishii, H. Uzumaki, K. Amano, T. Tokiwa, H. Mitsui, H. Saito, et al. 1995. Effects of T-helper 2-type cytokines, interleukin-3 (IL-3), IL-4, IL-5, and IL-6 on the survival of cultured human mast cells. Blood. 86:3705-3714.
    • (1995) Blood , vol.86 , pp. 3705-3714
    • Yanagida, M.1    Fukamachi, H.2    Ohgami, K.3    Kuwaki, T.4    Ishii, H.5    Uzumaki, H.6    Amano, K.7    Tokiwa, T.8    Mitsui, H.9    Saito, H.10
  • 52
    • 0030903307 scopus 로고    scopus 로고
    • RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis
    • Lloyd, C.M., A.W. Minto, M.E. Dorf, A. Proudfoot, T.N.C. Wells, D.J. Salant, and J.-C. Gutierrez-Ramos. 1997. RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J. Exp. Med. 185:1371-1380.
    • (1997) J. Exp. Med. , vol.185 , pp. 1371-1380
    • Lloyd, C.M.1    Minto, A.W.2    Dorf, M.E.3    Proudfoot, A.4    Wells, T.N.C.5    Salant, D.J.6    Gutierrez-Ramos, J.-C.7


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