Divergent effects of interleukin-4 and interferon-γ on macrophage- derived chemokine production: An amplification circuit of polarized T helper 2 responses

Blood

Volumn 92, Issue 8, 1998, Pages 2668-2671

  Bonecchi, Raffaella ^b   Sozzani, Silvano ^b   Stine, Johnny T ^b   Luini, Walter ^b   D'Amico, Giovanna ^b   Allavena, Paola ^b   Chantry, David ^b   Mantovani, Alberto ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; GAMMA INTERFERON; MESSENGER RNA; RECOMBINANT INTERLEUKIN 13; RECOMBINANT INTERLEUKIN 4;

ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL;

EID: 0032532054     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.8.2668.420k39_2668_2671     Document Type: Article

References (32)

1. Rollins BJ: Chemokines. Blood 90:909, 1997
2. Mantovani A: Chemokines are robust. Immunol Today (in press)
3. Baggiolini M: Chemokines and leukocyte traffic. Nature 392:565, 1998
4. Keiner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, Zlotnik A: Lymphotactin: A cytokine that represents a new class of chemokine. Science 266:1395, 1994
5. Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A, Schall TJ: A new class of membrane-bound chemokine with a CX3C motif. Nature 385:640, 1997
6. Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, Kakizaki M, Takagi S, Nomiyama H, Schall TJ, Yoshie O: Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91:521, 1997
7. Luster AD: Mechanisms of disease: Chemokines - Chemotactic cytokines that mediate inflammation. N Engl J Med 338:436, 1998
8. Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T: Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382:635, 1996
9. Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT: A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 391:799, 1998
10. Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW: Human macrophage derived chemokine (MDC) a novel chemoattractant for monocytes, monocyte derived dendritic cells, and natural killer cells. J Exp Med 185:1595, 1997
11. Yoshida R, Imai T, Hieshima K, Kusuda J, Baba M, Kitaura M, Nishimura M, Kakizaki M, Nomiyama H, Yoshie O: Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J Biol Chem 272:13803, 1997
12. Nagira M, Imai T, Hieshima K, Kusuda J, Ridanpaa M, Takagi S, Nishimura M, Kakizaki M, Nomiyama H, Yoshie O: Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13. J Biol Chem 272:19518, 1997
13. Yoshie O, Imai T, Nomiyama H: Novel lymphocyte-specific CC chemokines and their receptors. J Leukoc Biol 62:634, 1997
14. Adema GJ, Hartgers F, Verstraten R, deVries E, Marland G, Menon S, Foster J, Xu YM, Nooyen P, McClanahan T, Bacon KB, Figdor CG: A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387:713, 1997
15. Chang MS, Mcninch J, Elias C, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP: Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem 272:25229, 1997
16. Pal R, Garzinodemo A, Markham PD, Burns J, Brown M, Gallo RC, Devico AL: Inhibition of HIV-1 infection by the beta-chemokine MDC. Science 278:695, 1997
17. Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW: Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J Biol Chem 273:1764, 1998
18. Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A, Sinigaglia F: Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 187:129, 1998
19. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A: Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 187:875, 1998
20. Sallusto F, Mackay CR, Lanzavecchia A: Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005, 1997
21. Gerber BO, Zanni MP, Uguccioni M, Loetscher M, Mackay CR, Pichler WJ, Yawalkar N, Baggiolini M, Moser B: Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr Biol 7:836, 1997
22. Zingoni A, Soto H, Hedrick JA, Stoppacciaro A, Storlazzi CT, Sinigaglia F, D'Ambrosio D, O'Garra A, Robinson D, Rocchi M, Santoni A, Zlotnik A, Napolitano M: The chemokine receptor CCR8 is preferentially expressed by T helper 2 cells but not T helper 1 cells. J Immunol 161:547, 1998
23. Loetscher P, Uguccioni M, Bordoli L, Baggiolini M, Moser B, Chizzolini C, Dayer J-M: CCR5 is characteristic of Th1 lymphocytes. Nature 391:344, 1998
24. Qin SX, Rottman JB, Myers P, Kassam N, Weinblatt M, Loetscher M, Koch AE, Moser B, Mackay CR: The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 101:746, 1998
25. Romagnani S : The Th1/Th2 paradigm. Immunol Today 18:263, 1997
26. Abbas AK, Murphy KM, Sher A: Functional diversity of helper T lymphocytes. Nature 383:787, 1996
27. low thymocytes. (submitted)
28. Sozzani S, Ghezzi S, Iannolo G, Luini W, Borsatti A, Polentarutti N, Sica A, Locati M, Mackay C, Wells TNC, Biswas P, Vicenzi E, Poli G, Mantovani A: Interleukin-10 increases CCR5 expression and HIV infection in human monocytes. J Exp Med 187:439, 1998
29. Sozzani S, Luini W, Borsatti A, Polentarutti N, Zhou D, Piemonti L, D'Amico G, Power CA, Wells TN, Gobbi M, Allavena P, Mantovani A: Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J Immunol 159:1993, 1997
30. Penton-Rol G, Polentarutti N, Luini W, Borsatti A, Mancinelli R, Sica A, Sozzani S, Mantovani A: Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-g. J Immunol 160:3869, 1998
31. Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M: IL-2 Regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: Characterization of a predominant 3.4 Kb transcript containing CCR2B and CCR2A sequences. J Immunol 158:2689, 1997
32. Chantry D, DeMaggio AJ, Brammer H, Raport CJ, Wood CL, Schweickart VL, Epp A, Smith A, Stine JT, Walton K, Tjoelker L, Godiska R, Gray PW: Profile of human macrophage transcripts: Insights into macrophage biology and identification of novel chemokines. J Leukoc Biol 64:49, 1998