-
21
-
-
0025610263
-
Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: Similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors
-
(1990)
Gut
, vol.31
, pp. 1358-1364
-
-
Banerjee, A.K.1
Peters, T.J.2
-
31
-
-
0030239820
-
Hapten-induced model of murine inflammatory bowel disease: Mucosa immune responses and protection by tolerance
-
(1996)
J Immunol
, vol.157
, pp. 2174-2185
-
-
Elson, C.O.1
Beagley, K.W.2
Sharmanov, A.T.3
Fujihashi, K.4
Kiyono, H.5
Tennyson, G.S.6
Cong, Y.7
Black, C.A.8
Ridwan, B.W.9
McGhee, J.R.10
-
37
-
-
0032921746
-
A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis
-
(1999)
Eur J Immunol
, vol.29
, pp. 355-366
-
-
Okamoto, S.1
Watanabe, M.2
Yamazaki, M.3
Yajima, T.4
Hayashi, T.5
Ishii, H.6
Mukai, M.7
Yamada, T.8
Watanabe, N.9
Jameson, B.A.10
Hibi, T.11
-
38
-
-
0032884525
-
Protection of trinitrobenzene sulfonic acid-induced colitis by an interleukin 2-IgG2b fusion protein in mice
-
(1999)
Gastroenterology
, vol.117
, pp. 866-876
-
-
Stallmach, A.1
Wittig, B.2
Giese, T.3
Pfister, K.4
Hoffmann, J.C.5
Bulfone-Paus, S.6
Kunzendorf, U.7
Meuer, S.C.8
Zeitz, M.9
-
40
-
-
0031933806
-
Oxazolone-induced colitis in rats: Effects of budesonide, cyclosporin A, and 5-aminosalicylic acid
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 174-179
-
-
Ekstrom, G.M.1
-
48
-
-
0032550312
-
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells
-
(1998)
J Exp Med
, vol.187
, pp. 1225-1234
-
-
Simpson, S.J.1
Shah, S.2
Comiskey, M.3
de, J.Y.4
Wang, B.5
Mizoguchi, E.6
Bhan, A.K.7
Terhorst, C.8
-
51
-
-
0031114247
-
Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients
-
(1997)
J Immunol
, vol.158
, pp. 3464-3473
-
-
Aranda, R.1
Sydora, B.C.2
McAllister, P.L.3
Binder, S.W.4
Yang, H.Y.5
Targan, S.R.6
Kronenberg, M.7
-
52
-
-
0011042474
-
Blockade of IL-6 trans-signaling abrogates established experimental colitis in mice by suppression of T cell resistance against apoptosis
-
(in press)
-
(2000)
Nature Med
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
Mullberg, J.4
Jostock, T.5
Wirtz, S.6
Schuetz, M.7
Bartsch, B.8
Holtmann, M.B.C.9
Czaja, J.10
Schlaak, J.F.11
Lehr, H.A.12
Autschbach, F.13
Schurmann, G.14
Nishimoto, N.15
Yoshizaki, Y.16
Ito, H.17
Kishimoto, T.18
Galle, P.R.19
Rose-John, S.20
Neurath, M.21
more..
-
53
-
-
0029102210
-
Severe colitis in mice with aberrant thymic selection
-
(1995)
Immunity
, vol.3
, pp. 27-38
-
-
Hollander, G.A.1
Simpson, S.J.2
Mizoguchi, E.3
Nichogiannopoulou, A.4
She, J.5
Gutierrez, R.J.6
Bhan, A.K.7
Burakoff, S.J.8
Wang, B.9
Terhorst, C.10
-
54
-
-
0028111420
-
A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9402-9406
-
-
Wang, B.1
Biron, C.2
She, J.3
Higgins, K.4
Sunshine, M.J.5
Lacy, E.6
Lonberg, N.7
Terhorst, C.8
-
55
-
-
0033198580
-
Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
-
(1999)
Immunity
, vol.11
, pp. 349-358
-
-
Steinhoff, U.1
Brinkmann, V.2
Klemm, U.3
Aichele, P.4
Seiler, P.5
Brandt, U.6
Bland, P.W.7
Prinz, I.8
Zugel, U.9
Kaufmann, S.H.10
-
58
-
-
0030060392
-
T cells, but not thymic exposure to HLA-B27, are required for the inflammatory disease of HLA-B27 transgenic rats
-
(1996)
J Immunol
, vol.156
, pp. 794-803
-
-
Breban, M.1
Fernandez-Sueiro, J.L.2
Richardson, J.A.3
Hadavand, R.R.4
Maika, S.D.5
Hammer, R.E.6
Taurog, J.D.7
-
59
-
-
9544226450
-
Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats
-
(1996)
J Clin Invest
, vol.98
, pp. 945-953
-
-
Rath, H.C.1
Herfarth, H.H.2
Ikeda, J.S.3
Grenther, W.B.4
Hamm-TE, J.5
Balish, E.6
Taurog, J.D.7
Hammer, R.E.8
Wilson, K.H.9
Sartor, R.B.10
-
62
-
-
0033558364
-
Chronic intestinal inflammation in STAT-4 transgenic mice: Characterization of disease and adoptive transfer by TNF-plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens
-
(1999)
J Immunol
, vol.162
, pp. 1884-1888
-
-
Wirtz, S.1
Finotto, S.2
Kanzler, S.3
Lohse, A.W.4
Blessing, M.5
Lehr, H.A.6
Galle, P.R.7
Neurath, M.F.8
-
64
-
-
8544219681
-
The serum factor from patients with ulcerative colitis that induces T cell proliferation in the mouse thymus is interleukin-7
-
(1997)
J Clin Immunol
, vol.17
, pp. 282-292
-
-
Watanabe, M.1
Watanabe, N.2
Iwao, Y.3
Ogata, H.4
Kanai, T.5
Ueno, Y.6
Tsuchiya, M.7
Ishii, H.8
Aiso, S.9
Habu, S.10
Hibi, T.11
-
65
-
-
0032472838
-
Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa
-
(1998)
J Exp Med
, vol.187
, pp. 389-402
-
-
Watanabe, M.1
Ueno, Y.2
Yajima, T.3
Okamoto, S.4
Hayashi, T.5
Yamazaki, M.6
Iwao, Y.7
Ishii, H.8
Habu, S.9
Uehira, M.10
Nishimoto, H.11
Ishikawa, H.12
Hata, J.13
Hibi, T.14
-
67
-
-
0032540266
-
Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice
-
(1998)
Cell
, vol.93
, pp. 189-201
-
-
Bush, T.G.1
Savidge, T.C.2
Freeman, T.C.3
Cox, H.J.4
Campbell, E.A.5
Mucke, L.6
Johnson, M.H.7
Sofroniew, M.V.8
-
70
-
-
0033000343
-
IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
-
(1999)
Am J Physiol
, vol.276
-
-
Schultz, M.1
Tonkonogy, S.L.2
Sellon, R.K.3
Veltkamp, C.4
Godfrey, V.L.5
Kwon, J.6
Grenther, W.B.7
Balish, E.8
Horak, I.9
Sartor, R.B.10
-
73
-
-
0030942666
-
Altered immune responses in interleukin 10 transgenic mice
-
(1997)
J Exp Med
, vol.185
, pp. 2101-2110
-
-
Hagenbaugh, A.1
Sharma, S.2
Dubinett, S.M.3
Wei, S.Y.4
Aranda, R.5
Cheroutre, H.6
Fowell, D.J.7
Binder, S.8
Tsao, B.9
Locksley, R.M.10
Moore, K.W.11
Kronenberg, M.12
-
75
-
-
0032530697
-
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice
-
(1998)
J Immunol
, vol.161
, pp. 3143-3149
-
-
Davidson, N.J.1
Hudak, S.A.2
Lesley, R.E.3
Menon, S.4
Leach, M.W.5
Rennick, D.M.6
-
76
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.B.8
-
77
-
-
0032536530
-
The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
-
(1998)
J Exp Med
, vol.187
, pp. 571-578
-
-
Spencer, S.D.1
Di, M.F.2
Hooley, J.3
Pitts, M.S.4
Bauer, M.5
Ryan, A.M.6
Sordat, B.7
Gibbs, V.C.8
Aguet, M.9
-
78
-
-
0029061801
-
Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice
-
(1995)
Nat Genet
, vol.10
, pp. 143-150
-
-
Rudolph, U.1
Finegold, M.J.2
Rich, S.S.3
Harriman, G.R.4
Srinivasan, Y.5
Brabet, P.6
Boulay, G.7
Bradley, A.8
Birnbaumer, L.9
-
86
-
-
0032118427
-
Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation
-
(1998)
Immunity
, vol.9
, pp. 81-91
-
-
Snapper, S.B.1
Rosen, F.S.2
Mizoguchi, E.3
Cohen, P.4
Khan, W.5
Liu, C.H.6
Hagemann, T.L.7
Kwan, S.P.8
Ferrini, R.9
Davidson, L.10
Bhan, A.K.11
Alt, F.W.12
-
87
-
-
0030765924
-
Jaks, STATs, cytokine signal transduction, and immunoregulation: Are we there yet?
-
(1997)
Immunity
, vol.7
, pp. 1-11
-
-
O'Shea, J.J.1
-
89
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
92
-
-
0032033419
-
Cytokines induce the development of functionally heterogeneous T helper cell subsets
-
(1998)
Immunity
, vol.8
, pp. 275-283
-
-
O'Garra, A.1
-
93
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
(1997)
Am J Pathol
, vol.150
, pp. 823-832
-
-
Parronchi, P.1
Romagnani, P.2
Annunziato, F.3
Sampognaro, S.4
Becchio, A.5
Giannarini, L.6
Maggi, E.7
Pupilli, C.8
Tonelli, F.9
Romagnani, S.10
-
94
-
-
0031888743
-
Interleukin-12 expression is focally enhanced in the gastric mucosa of pediatric patients with Crohn's disease
-
(1998)
Am J Pathol
, vol.152
, pp. 667-672
-
-
Berrebi, D.1
Besnard, M.2
Fromont-Hankard, G.3
Paris, R.4
Mougenot, J.F.5
De Lagausie, P.6
Emilie, D.7
Cezard, J.P.8
Navarro, J.9
Peuchmaur, M.10
-
99
-
-
0030209985
-
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
(1996)
J Immunol
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
Klein, J.S.4
de la Motte, C.5
Strong, S.A.6
Fiocchi, C.7
Strober, W.8
-
103
-
-
0032425062
-
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
-
(1998)
Infect Immun
, vol.66
, pp. 5157-5166
-
-
Kullberg, M.C.1
Ward, J.M.2
Gorelick, P.L.3
Caspar, P.4
Hieny, S.5
Cheever, A.6
Jankovic, D.7
Sher, A.8
-
106
-
-
0031043778
-
Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease
-
(1997)
Lancet
, vol.349
, pp. 521-524
-
-
Stack, W.A.1
Mann, S.D.2
Roy, A.J.3
Heath, P.4
Sopwith, M.5
Freeman, J.6
Holmes, G.7
Long, R.8
Forbes, A.9
Kamm, M.A.10
-
108
-
-
0032989443
-
Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease
-
(1999)
Gastroenterology
, vol.117
, pp. 58-64
-
-
Sands, B.E.1
Bank, S.2
Sninsky, C.A.3
Robinson, M.4
Katz, S.5
Singleton, J.W.6
Miner, P.B.7
Safdi, M.A.8
Galandiuk, S.9
Hanauer, S.B.10
Varilek, G.W.11
Buchman, A.L.12
Rodgers, V.D.13
Salzberg, B.14
Cai, B.15
Loewy, J.16
DeBruin, M.F.17
Rogge, H.18
Shapiro, M.19
Schwertschlag, U.S.20
more..
-
111
-
-
0029826678
-
Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin alpha 4 beta 7
-
(1996)
Gastroenterology
, vol.111
, pp. 1373-1380
-
-
Hesterberg, P.E.1
Winsor, H.D.2
Briskin, M.J.3
Soler, F.D.4
Merrill, C.5
Mackay, C.R.6
Newman, W.7
Ringler, D.J.8
-
114
-
-
0033114118
-
ICAM-1 antisense therapy: A new treatment concept on Crohn disease? Placebo controlled study of ICAM-1 antisense oligonucleotide therapy in Crohn disease
-
(1999)
Z Gastroenterol
, vol.37
, pp. 313-315
-
-
Martignoni, M.E.1
Friess, H.2
-
115
-
-
0031901348
-
Viral vectors expressing immunoregulatory cytokines to treat inflammatory bowel disease
-
(1998)
Gut
, vol.42
, pp. 460-461
-
-
MacDonald, T.T.1
-
116
-
-
0033055144
-
Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure
-
(1999)
Gut
, vol.44
, pp. 800-807
-
-
Wirtz, S.1
Galle, P.R.2
Neurath, M.F.3
-
124
-
-
9344232792
-
Attenuation of the inflammatory response in an animal colitis model by neutrophil inhibitory factor, a novel beta 2-integrin antagonist
-
(1996)
Scand J Gastroenterol
, vol.31
, pp. 786-791
-
-
Meenan, J.1
Hommes, D.W.2
Mevissen, M.3
Dijkhuizen, S.4
Soule, H.5
Moyle, M.6
Buller, H.R.7
ten Kate, F.W.8
Tytgat, G.N.9
van Deventer, S.J.10
-
127
-
-
0030818051
-
Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice
-
(1997)
Eur J Immunol
, vol.27
, pp. 1743-1750
-
-
Neurath, M.F.1
Fuss, I.2
Pasparakis, M.3
Alexopoulou, L.4
Haralambous, S.5
Meyer-zum Buschenfelde, K.H.6
Strober, W.7
Kollias, G.8
-
132
-
-
0031751443
-
Effects of the anti-ICAM-1 monoclonal antibody on dextran sodium sulphate-induced colitis in rats
-
(1998)
J Gastroenterol Hepatol
, vol.13
, pp. 945-949
-
-
Taniguchi, T.1
Tsukada, H.2
Nakamura, H.3
Kodama, M.4
Fukuda, K.5
Saito, T.6
Miyasaka, M.7
Seino, Y.8
-
136
-
-
0030980684
-
An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice
-
(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 988-1000
-
-
Bennett, C.F.1
Kornbrust, D.2
Henry, S.3
Stecker, K.4
Howard, R.5
Cooper, S.6
Dutson, S.7
Hall, W.8
Jacoby, H.I.9
-
138
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
-
(1999)
J Clin Invest
, vol.104
, pp. 383-389
-
-
Su, C.G.1
Wen, X.2
Bailey, S.T.3
Jiang, W.4
Rangwala, S.M.5
Keilbaugh, S.A.6
Flanigan, A.7
Murthy, S.8
Lazar, M.A.9
Wu, G.D.10
-
139
-
-
0033603241
-
RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
-
(1999)
Cell
, vol.97
, pp. 889-901
-
-
Hofmann, M.A.1
Drury, S.2
Fu, C.3
Qu, W.4
Taguchi, A.5
Lu, Y.6
Avila, C.7
Kambham, N.8
Bierhaus, A.9
Nawroth, P.10
Neurath, M.F.11
Slattery, T.12
Beach, D.13
McClary, J.14
Nagashima, M.15
Morser, J.16
Stern, D.17
Schmidt, A.M.18
|