Attenuation of the inflammatory response in an animal colitis model by neutrophil inhibitory factor, a novel β2-integrin antagonist

Scandinavian Journal of Gastroenterology

Volumn 31, Issue 8, 1996, Pages 786-791

  Meenan, J ^a   Hommes, D W ^b   Mevissen, M ^b   Dijkhuizen, S ^b   Soule, H ^b   Moyle, M ^b   Buller, H R ^b   Ten Kate, F W ^b   Tytgat, G N J ^b   Van Deventer, S J H ^b  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Adhesion; Colitis; Eocosanoids; Integrin

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; FORMALDEHYDE; GLYCOPROTEIN; INTEGRIN; LEUKOTRIENE B4; MYELOPEROXIDASE; NEUTROPHIL INHIBITORY FACTOR; PROSTAGLANDIN E2; THROMBOXANE B2;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; COLITIS; CONTROLLED STUDY; DRUG EFFICACY; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLAMMATORY INFILTRATE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEUTROPHIL; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RABBIT;

EID: 9344232792     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529609010353     Document Type: Article

References (30)

1. Wallace JL. Immunopharmacology of eicosanoids in the gastrointestinal tract. In: Wallace JL, editor. Immunopharmacology of the gastrointestinal system. London: Academic Press 1993: 137-54.
2. McColl SR, Showell HJ. Neutrophil derived inflammatory mediators. In: Hellewell PG, Williams TJ, editors. Immunopharmacology of neutrophils. London: Academic Press 1994: 95-114.
3. Monajemi H, Meenan J, Lamping R, Obradov DO, Radema SA, Tytgat GNJ, et al. Mucosal levels of bactericidal/permeability increasing protein arc raised in inflammatory bowel disease. Gastroenterology. In press.
4. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multi-step paradigm. Cell 1994;76: 301-14.
5. Adams DH, Shaw S. Leucocyte-endothelial interactions and regulation of leucocyte migration. Lancet 1994;343:831-6.
6. Hollander D. Integrins: a family of cell surface adhesion receptors - relevance to intestinal immune defenses. Eur J Gastroenterol Hepatol 1993;5:593-9.
7. Diamond MS, Springer TA. A sub-population of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol 1993;120:545-6.
8. Etzioni A, Frydman M, Pollack S, Avidor I, Phillips ML, Paulson JC, et al. Recurrent severe infections caused by a novel leukocyte adhesion deficiency. N Engl J Med 1992;327: 1789-92.
9. Muchowski PJ, Zhang L, Chang ER, Soule HR, Plow EF, Moyle M. Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18. J Biol Chem 1994;269:26419-23.
10. Hack CE, Eerenberg-Belmer AJM, Hannema AJ, Out TA, Aalberse RC. Polyethylene glycol enhances the binding of C1q to circulating immune complexes. J Immunol Methods 1981;44: 211-21.
11. Strober W. Animal models of inflammatory bowel disease- an overview. Dig Dis Sci 1985;30:3s-10s.
12. Fiocchi C. Cytokines and animal models: a combined path to inflammatory bowel disease pathogenesis. Gastroenterology 1993;104:1202-5.
13. Cominelli F, Nast CC, Duchini A, Lee M. Recombinant interleukin-1 receptor antagonist blocks the pro-inflammatory activity of endogenous interleukin-1 in rabbit immune colitis. Gastroenterology 1992;103:65-71.
14. 4 in rabbit colitis. Gastroenterology 1987;92:33-9.
15. Hodgson HJF, Potter BJ, Skinner J, Jewell DP. Immunecomplex mediated colitis in rabbits: an experimental model. Gut 1978;19:225-32.
16. Lichtenstein GR. Medical therapies for inflammatory bowel disease. Curr Opin Gastroenterol 1994;10:390-403.
17. Carlos TM, Harlan JM. Leukocyte endothelial adhesion molecules. Blood 1994;84:2068-101.
18. Mevissen M, Meenan J, Soule HR, Moyle M, Buller HR, van Deventer SJH. Inhibition of neutrophil migration across and adherence to monolayers of endothelial cells by neutrophil inhibitory factor (NIF). Proceedings XIV Cardiovascular Disease Inernational Symposium, Washington, 1994.
19. Meenan J, Mevissen M, Radema SA, Monajemi H, Tytgat GNJ, van Deventer SJH. Factors influencing neutrophil adhesion to epithelial apical membranes. Gut. In press.
20. Barnard JW, Biro MG, Lo SK, Ohno S, Carozza MA, Moyle M, et al. Neutrophil inhibitory factor prevents neutrophil-dependent lung injury. J Immunol 1995;155:4876-81.
21. Wallace JL. Eicosanoids. In: Targan SR, Shanahan F, editors. Inflammatory bowel disease: from bench to bedside. Baltimore: Williams and Wilkins, 1994:123-32.
22. Hommes DW, Meenan J, de Haas M, ten Kate FJW, von den Borne AEGK, Tytgat GNJ, et al. Soluble FcgIII (CD16) and eicosanoid levels in gut lavage fluid from patients with inflammatory bowel disease: relation with mucosal inflammation. Gut. In press.
23. Au B, Williams TJ, Collins PD. Zymosan induced IL-8 release from human neutrophils involves activation via the CD11b/ CD18 receptor and endogenous platelet activating factor. J Immunol 1994;152:5411-9.
24. 2-integrin to enhance phagocytosis. J Immunol 1994;153:3199-209.
25. Wallace JL, Whittle BJR, Boughton-Smith NK. Prostaglandin protection of rat colonic mucosa from damage induced by ethanol. Dig Dis Sci 1985;30:866-76.
26. 2 before and after induction of colitis with trinitrobenzenesulfonic acid in rats decreases inflammation. Gastroenterology 1989;96:1290-300.
27. Buell MG, Berin MC. Neutrophil-independence of the initiation of colonic injury. Dig Dis Sci 1994;39:2575-88.
28. Wallace JL, Higa A, McKnight GW, MacIntyre DE. Prevention and reversal of experimental colitis by a monoclonal antibody which inhibits leukocyte adherence. Inflammation 1992;16: 343-54.
29. Winn RK, Harlan JM. CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits. J Clin Invest 1993;92:1168-73.
30. 1-dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigration. FASEB J 1995;9:1103-11.