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note
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Supported by INSERM, CNRS, Assistance Publique/Hôpitaux de Paris, and Université Paris V. We thank P. Golstein, J. DiSanto, C. Schiff, L. Leserman, and D. Guy-Grand for critical comments. J. DiSanto for communicating unpublished results on pTαx-γc-deficient mice, and N. Guglietta and C. Beziers-LaFosse for editing the manuscript. Because of the space limitations, we were not able to acknowledge the contributions of all investigators to this growing field.
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