Function of the pre-T-cell receptor α chain in T-cell development and allelic exclusion at the T-cell receptor β locus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 5, 1996, Pages 2169-2173

  Xu, Yang ^a   Davidson, Laurie ^b   Alt, Frederick W ^b   Baltimore, David ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

allelic exclusion; gene targeting; T cell differentiation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ALLELE; ANIMAL CELL; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO CELL; GENE TARGETING; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE;

ALLELES; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; DNA PRIMERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HETEROZYGOTE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES;

EID: 0029892252     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.5.2169     Document Type: Article

References (29)

1. Shortman, K. (1992) Curr. Opin. Immunol. 4, 140-146.
2. Raulet, D. H., Garman, R. D., Saito, H. & Tonegawa, S. (1985) Nature (London) 314, 103-107.
3. Snodgrass, R. H., Dembic, Z., Steinmetz, M. & von Boehmer, H. (1985) Nature (London) 315, 232-233.
4. Mombaerts, P., Clarke, A. R., Rudnicki, M. A., Iacomini, J., Itohara, S., Lafaille, J. J., Wang, L., Ichikawa, Y., Jaenisch, R., Hooper, M. L. & Tonagawa, S. (1992) Nature (London) 360, 225-231.
5. Shinkai, Y., Koyasu, S., Nakayama, K., Murphy, K. M., Loh, D. Y., Reinherz, E. L. & Alt, F. W. (1993) Science 259, 822-825.
6. Kishi, H., Borgulya, P., Scott, B., Karjalainen, K., Traunecker, A., Kaufman, J. & von Boehmer, H. (1991) EMBO J. 10, 93-100.
7. Groettrup, M., Baron, A., Griffiths, G., Palacios, R. & von Boehmer, H. (1992) EMBO J. 7, 2735-2746.
8. Saint-Ruf, C., Ungewiss, K., Groettrup, M., Bruno, L., Fehling, H. J. & von Boehmer, H. (1994) Science 266, 1208-1212.
9. Karasuyama, H., Rolink, A., Shinkai, Y., Young, F., Alt, F. W. & Melchers, F. (1994) Cell 77, 133-143.
10. Kitamura, D., Kudo, A., Schaal, S., Muller, W., Melchers, F. & Rajewsky, K. (1992) Cell 69, 823-831.
11. Kitamura, D., Roes, J., Kuhn, R. & Rajewsky, K. (1991) Nature (London) 350, 423-426.
12. Storb, U., Pinkert, C., Arp, B., Engler, P., Gollanhon, K. & Manz, J. (1986) J. Exp. Med. 164, 627-652.
13. Nussenzweig, M., Shaw, A., Sinn, E., Danner, D. B., Holmes, K. L., Morse, H. C. & Leder, P. (1987) Science 236, 816-819.
14. Kitamura, D. & Rajewsky, K. (1992) Nature (London) 356, 154-156.
15. Uematsu, Y., Ryser, S., Dembić, Z., Borgulya, P., Krimpenfort, P., Berns, A., von Boehmer, H. & Steinmetz, M. (1988) Cell 52, 831-841.
16. Chen, J., Lansford, R., Stewart, V., Young, F. & Alt, F. (1993) Proc. Natl. Acad. Sci. USA 90, 4528-4532.
17. Fehling, H. J., Krotkova, A., Saint-Ruf, C. & von Boehmer, H. (1995) Nature (London) 375, 795-798.
18. Bothwell, A., Yancopoulos, G. D. & Alt, F. W. (1989) Methods for Cloning and Analysis of Eukaryotic Genes (Jones & Bartlett, Boston).
19. Li, E., Bestor, T. H. & Jaenisch, R. (1992) Cell 69, 915-926.
20. Mansour, S. L., Thomas, K. R. & Cepecchi, M. R. (1988) Nature (London) 336, 348-352.
21. Mortensen, R. M., Conner, D. A., Chao, S., Geisterfer, A. A. & Seidman, J. G. (1922) Mol. Cell. Biol. 12, 2391-2395.
22. Murphy, K. M., Heimberger, A. B. & Loh, D. Y. (1990) Science 250, 1720-1722.
23. Parks, D. R., Lanier, L. L. & Herzenberg, L. A. (1986) Handbook of Experimental Immunology (Blackwell Scientific, London), pp. 29.1-29.21.
24. Forster, L. Vieira, P. & Rajewsky, K. (1989) Int. Immunol. 1, 321-331.
25. Zhou, R., Alt, F. W., Davidson, L., Orkin, S. H. & Swat, W. (1995) Nature (London) 374, 470-473.
26. Shinkai, Y., Ma, A., Cheng, H.-L. & Alt, F. W. (1995) Immunity 2, 401-411.
27. Malissen, M., Gillet, A., Ardouin, L., Bouvier, G., Trucy, J., Ferrier, P., Vivier, E. & Malissen, B. (1995) EMBO J. 14, 4641-4653.
28. Lin, W.-C. & Desiderio, S. (1993) Science 260, 953-959.
29. Dudley, E. C., Petrie, H. T., Shah, L. M., Owen, M. J. & Hayday, A. C. (1994) Immunity 1, 83-93.