-
1
-
-
0027413591
-
Overview of biochemical abnormalities and molecular genetics of adenosine deaminase deficiency
-
Hirschhorn, R. Overview of biochemical abnormalities and molecular genetics of adenosine deaminase deficiency. Pediatr. Res. 33, S35-S41 (1993).
-
(1993)
Pediatr. Res.
, vol.33
-
-
Hirschhorn, R.1
-
2
-
-
0027403374
-
Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
-
Noguchi, M. et al. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73, 147 (1993).
-
(1993)
Cell
, vol.73
, pp. 147
-
-
Noguchi, M.1
-
3
-
-
0029164841
-
Mutations of Jak-3 gene in patients with autosomal severe combined immunodeficiency (SCID)
-
Macchi, P. et al. Mutations of Jak-3 gene in patients with autosomal severe combined immunodeficiency (SCID). Nature 377, 65-68 (1995).
-
(1995)
Nature
, vol.377
, pp. 65-68
-
-
Macchi, P.1
-
4
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell, S. et al. Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development. Science 270, 797-800 (1995).
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russell, S.1
-
5
-
-
0027420443
-
Haploidentical bone marrow stem cell transplantation in human severe combined immunodeficiency
-
Buckley, R. et al. Haploidentical bone marrow stem cell transplantation in human severe combined immunodeficiency. Semin. Hematol. 30, 92-104 (1993).
-
(1993)
Semin. Hematol.
, vol.30
, pp. 92-104
-
-
Buckley, R.1
-
6
-
-
0027477193
-
Immune reconstitution in severe combined immunodeficiency disease after lectin-treated, T-cell-depleted haplocompatible bone marrow transplantation
-
Dror, Y. et al. Immune reconstitution in severe combined immunodeficiency disease after lectin-treated, T-cell-depleted haplocompatible bone marrow transplantation. Blood 81, 2021-2030 (1993).
-
(1993)
Blood
, vol.81
, pp. 2021-2030
-
-
Dror, Y.1
-
7
-
-
0027939098
-
Relationship between patterns of engraftment in peripheral blood and immune reconstitution after allogeneic bone marrow transplantation for (severe) combined immunodeficiency
-
van Leeuwen, J. et al. Relationship between patterns of engraftment in peripheral blood and immune reconstitution after allogeneic bone marrow transplantation for (severe) combined immunodeficiency, Blood 84, 3936-3947 (1994).
-
(1994)
Blood
, vol.84
, pp. 3936-3947
-
-
Van Leeuwen, J.1
-
8
-
-
0028807727
-
T lymphocyte-directed gene therapy for ADA-SCID: Initial trial results after 4 years
-
Blaese, R. et al. T lymphocyte-directed gene therapy for ADA-SCID: Initial trial results after 4 years. Science 270, 475-480 (1995).
-
(1995)
Science
, vol.270
, pp. 475-480
-
-
Blaese, R.1
-
9
-
-
0028789792
-
Gene therapy in peripheral blood lymphocytes and bone marrow for ADA-immunodeficient patients
-
Bordignon, C. et al. Gene therapy in peripheral blood lymphocytes and bone marrow for ADA-immunodeficient patients. Science 270, 470-475 (1995).
-
(1995)
Science
, vol.270
, pp. 470-475
-
-
Bordignon, C.1
-
10
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
-
Cao, X. et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 2, 223-238 (1995).
-
(1995)
Immunity
, vol.2
, pp. 223-238
-
-
Cao, X.1
-
11
-
-
0028339282
-
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
-
Johnston, J. et al. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 370, 151-153 (1994).
-
(1994)
Nature
, vol.370
, pp. 151-153
-
-
Johnston, J.1
-
12
-
-
0028244396
-
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
-
Witthuhn, B. et al. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 370, 153-157 (1994).
-
(1994)
Nature
, vol.370
, pp. 153-157
-
-
Witthuhn, B.1
-
13
-
-
0029550822
-
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
-
Park, S. et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 3, 771-782 (1995).
-
(1995)
Immunity
, vol.3
, pp. 771-782
-
-
Park, S.1
-
14
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka, T. et al. Defective lymphoid development in mice lacking Jak3. Science 270, 800-802 (1995).
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
-
15
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
-
Thomis, D., Gurniak, C., Tivol, E., Sharpe, A. & Berg, L. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 270, 794-797 (1995).
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.1
Gurniak, C.2
Tivol, E.3
Sharpe, A.4
Berg, L.5
-
16
-
-
0030008035
-
Retroviral-mediated gene correction for X-linked severe combined immunodeficiency
-
Candotti, F. et al. Retroviral-mediated gene correction for X-linked severe combined immunodeficiency. Blood 87, 3097-3102 (1996).
-
(1996)
Blood
, vol.87
, pp. 3097-3102
-
-
Candotti, F.1
-
17
-
-
0029866741
-
Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the γ⊂ gene
-
Taylor, N. et al. Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the γ⊂ gene. Blood 87, 3103-3107 (1996).
-
(1996)
Blood
, vol.87
, pp. 3103-3107
-
-
Taylor, N.1
-
18
-
-
0029896604
-
In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction
-
Candotti, F. et al. In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction. J. Exp. Med. 183, 2687-2692 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2687-2692
-
-
Candotti, F.1
-
19
-
-
0029056481
-
Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells
-
Allay, J., Dumenco, L., Koc, O., Liu, L & Gerson, S. Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells, Blood 85, 3342-3351 (1995).
-
(1995)
Blood
, vol.85
, pp. 3342-3351
-
-
Allay, J.1
Dumenco, L.2
Koc, O.3
Liu, L.4
Gerson, S.5
-
20
-
-
0000276084
-
Autocrine stimulation after transfer of the granu locyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway
-
Laker, C. et al. Autocrine stimulation after transfer of the granu locyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway. Proc. Natl. Acad. Sci. USA 84, 8458-8462 (1987).
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8458-8462
-
-
Laker, C.1
-
21
-
-
0029865455
-
A gene transfer strategy for making bone marrow cells resistant to trimetrexate
-
Spencer, H., Sleep, S., Rehg, J., Blakley, R. & Sorrentino, B. A gene transfer strategy for making bone marrow cells resistant to trimetrexate. Blood 87, 2579-2587 (1996).
-
(1996)
Blood
, vol.87
, pp. 2579-2587
-
-
Spencer, H.1
Sleep, S.2
Rehg, J.3
Blakley, R.4
Sorrentino, B.5
-
22
-
-
0030862399
-
Human severe combined immunodeficiency: Genetic, phenotypic, and functional diversity in one hundred eight infants
-
Buckley, R. et al. Human severe combined immunodeficiency: Genetic, phenotypic, and functional diversity in one hundred eight infants. J. Pediatr. 130, 378-387 (1997).
-
(1997)
J. Pediatr.
, vol.130
, pp. 378-387
-
-
Buckley, R.1
-
24
-
-
0030940510
-
phox-deficient model of chronic granulomatous disease
-
phox-deficient model of chronic granulomatous disease. Blood 89, 2268-2275 (1997).
-
(1997)
Blood
, vol.89
, pp. 2268-2275
-
-
Mardiney III, M.1
-
25
-
-
0029902033
-
Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency
-
Hirschhorn, R. et al. Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency. Nature Genet. 13, 290-295 (1996).
-
(1996)
Nature Genet.
, vol.13
, pp. 290-295
-
-
Hirschhorn, R.1
-
26
-
-
10544244162
-
Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells
-
Stephan, V. et al. Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells. N. Engl. J. Med. 335, 1563-1567 (1996).
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1563-1567
-
-
Stephan, V.1
-
27
-
-
0031017533
-
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-STAT pathways
-
Luo, H. et al. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-STAT pathways. Mol. Cell. Biol. 17, 1562-1571 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1562-1571
-
-
Luo, H.1
-
28
-
-
0028938172
-
An amino acid substitution in the Drosophila hop Tum-1 Jak kinase causes leukemia-like hematopoietic defects
-
Luo, H., Hanratty, W. & Dearolf, C. An amino acid substitution in the Drosophila hop Tum-1 Jak kinase causes leukemia-like hematopoietic defects. EMBO J. 14, 1412-1420 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 1412-1420
-
-
Luo, H.1
Hanratty, W.2
Dearolf, C.3
-
29
-
-
0031587038
-
Microinjected cDNA encoding JAK2 protein-tyrosine kinase induces DMA synthesis in NIH 3T3 cells
-
Smith, M., Duhe, R., Liu, Y. & Farrar W. Microinjected cDNA encoding JAK2 protein-tyrosine kinase induces DMA synthesis in NIH 3T3 cells. FEBS Lett. 408, 327-330 (1997).
-
(1997)
FEBS Lett.
, vol.408
, pp. 327-330
-
-
Smith, M.1
Duhe, R.2
Liu, Y.3
Farrar, W.4
-
30
-
-
0022767368
-
Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production
-
Miller, A. & Buttimore, C. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell. Biol. 6, 2895-2902 (1986).
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2895-2902
-
-
Miller, A.1
Buttimore, C.2
-
31
-
-
0023871422
-
A safe packaging line for gene transfer: Separating viral genes on two different plasmids
-
Markowitz, D., Goff, S. & Bank, A. A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62, 1120-1124 (1988).
-
(1988)
J. Virol.
, vol.62
, pp. 1120-1124
-
-
Markowitz, D.1
Goff, S.2
Bank, A.3
-
32
-
-
0025832928
-
Survival and retrovirus infection of murine hematopoietic stem cells in vitro: Effects of 5-FU and method of infection
-
Bodine, D., McDonagh, K., Seidel, N. & Nienhuis, A. Survival and retrovirus infection of murine hematopoietic stem cells in vitro: Effects of 5-FU and method of infection. Exp. Hematol. 19, 206-212 (1991).
-
(1991)
Exp. Hematol.
, vol.19
, pp. 206-212
-
-
Bodine, D.1
McDonagh, K.2
Seidel, N.3
Nienhuis, A.4
-
33
-
-
0024380889
-
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells
-
Bodine, D., Karlsson, S. & Nienhuis, A. Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 86, 8897-8901 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8897-8901
-
-
Bodine, D.1
Karlsson, S.2
Nienhuis, A.3
-
34
-
-
0026637623
-
Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1
-
Sorrentino, B. et al. Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science 257, 99-103 (1992).
-
(1992)
Science
, vol.257
, pp. 99-103
-
-
Sorrentino, B.1
|