Restoration of thymocyte development and function in zap-70(-/-) mice by the Syk protein tyrosine kinase

Immunity

Volumn 7, Issue 3, 1997, Pages 369-377

  Gong, Qian ^a   White, Lynn ^a   Johnson, Robin ^a   White, Mike ^a   Negishi, Izumi ^b   Thomas, Matthew ^a   Chan, Andrew C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NIPPON ROCHE RESEARCH CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ARTICLE; CELL MATURATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GROWTH REGULATION; LYMPHOCYTE DIFFERENTIATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THYMOCYTE;

EID: 0030756320     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80358-1     Document Type: Article

References (56)

1. Allen, J., Forbush, K., and Perlmutter, R. (1992). Functional dissection of the Ick proximal promoter. Mol. Cell. Biol. 12, 2758-2768.
2. Appleby, M.W., Gross, J.A., Cooke, M.P., Levin, S.D., Qian, X., and Perlmutter, R.M. (1992). Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70, 751-763.
3. + thymic selection in humans lacking ZAP-70 kinase. Cell 76, 947-958.
4. Benator, T., Carsetti, R., Furlonger, C., Kamalia, N., Mak, T., and Paige, C.J. (1996). Immunoglobulin-mediated signal transduction in B cells from CD45-deficient mice. J. Exp. Med. 183, 329-334.
5. Bu, J.-Y., Shaw, A.S., and Chan, A.C. (1995). Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance. Proc. Natl. Acad. Sci. USA 92, 5106-5110.
6. Bubeck-Wardenburg, J., Fu, C.F., Jackman, J., Flotow, H., Wilkinson, S., Williams, D., Kong, G.H., Johnson, R., Chan, A.C., and Findell, P. (1996). Phosphorylation of SLP-76 by the ZAP-70 protein tyrosinekinase is required for T cell receptor function. J. Biol. Chem. 271, 19641-19644.
7. + thymocytes, and B cell maturation. J. Exp. Med. 183, 1707-1718.
8. Chan, A., Iwashima, M., Turck, C., and Weiss, A. (1992). ZAP-70: a 70 kDa protein tyrosine kinase that associates with the TCR ζ-chain. Cell 71, 649-662.
9. Chan, A., Desai, D.M., and Weiss, A. (1994a). Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 14, 555-592.
10. Chan, A., Kadlecek, T., Elder, M., Filipovich, A., Grey, J., Iwashima, M., Parslow, T., and Weiss, A. (1994b). ZAP-70 protein tyrosine kinase deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264, 1599-1601.
11. Chan, A., van Oers, N., Tran, A., Turka, L., Law, C.-L., Ryan, J., Clark, E., and Weiss, A. (1994c). Differential expression of ZAP-70 and Syk protein tyrosine kinases and role of this family of PTKs in T cell antigen receptor signaling. J. Immunol. 152, 4758-4766.
12. Chan, A.C., Dalton, M., Johnson, R., Kong, G.-h., Wang, T., Thoma, R., and Kurosaki, T. (1995). Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14, 2499-2508.
13. Cheng, A.M., and Chan, A.C. (1997). Protein tyrosine kinases in thymocyte development. Curr. Opin. Immunol., in press.
14. Cheng, A.M., Rowley, R.B., Pao, W., Hayday, A., Bolen, J.B., and Pawson, T. (1995). Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378, 303-306.
15. Cheng, A.M., Negishi, I., Anderson, S.J., Chan, A.C., Bolen, J., Loh, D.Y., and Pawson, T. (1997). Arrested development of double negative thymocytes in mice lacking both the Syk and ZAP-70 tyrosine kinases. Proc. Natl. Acad. Sci. USA, in press.
16. Chu, D.H., Spits, H., Peyron, J.-F., Rowley, R.B., Bolen, J.B., and Weiss, A. (1996). The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen recpetor signaling. EMBO J. 15, 6251-6261.
17. Costa, T.E., Franke, R., Sanchez, M., Misulovin, Z., and Nussenzweig, M.C. (1992). Functional reconstitution of an immunoglobulin antigen receptor in T cells. J. Exp. Med. 175, 1669-1676.
18. Couture, C., Baier, G., Altman, A., and Mustelin, T. (1994). p56lck-independent activation and tyrosine phosphorylation of p72syk by T-cell antigen receptor/CD3 stimulation. Proc. Natl. Acad. Sci. USA 91, 5301-5305.
19. Cyster, J.G., Healy, J.I., Kishihara, K., Mak, T.W., Thomas, M.L., and Goodnow, C.C. (1996). Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature 381, 325-328.
20. Elder, M., Lin, D., Clever, J., Chan, A., Hope, T., Weiss, A., and Parslow, T. (1994). Human severe combined immunodeficiency due to adefectin ZAP-70 - a T-cell receptor-associated tyrosine kinase. Science 264, 1596-1599.
21. El-Hillal, O., Kurosaki, T., Yamamura, H., Kinet, J.-P., and Scharenberg, A.M. (1997). syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction. Proc. Natl. Acad. Sci. USA 94, 1919-1924.
22. Fujise, S., Matsuzaki, G., Kishihara, K., Kadena, T., Molina, T., and Nomoto, K. (1996). The role of p56lckin the development of gamma deltaT cells and their function during an infection by Listeria monocytogenes. J. Immunol. 157, 247-254.
23. Gelfand, E.W., Weiberg, K., Mazer, B.D., Kadlecek, T.A., and Weiss, A. (1995). Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. J. Exp. Med. 182, 1057-1065.
24. Groves, T., Smiley, P., Cooke, M.P., Forbush, K., Perlmutter, R.M., and Guidos, C.J. (1996). Fyn can partially substitute for Lck in T lymphocyte development. Immunity 5, 417-428.
25. Iwashima, M., Irving, B., van Oers, N., Chan, A., and Weiss, A. (1994). The sequential interaction of two cytoplasmic protein tyrosine kinases in T cell antigen receptor signaling. Science 263, 1163-1139.
26. Karnitz, L., Sutor, S.L., Torigoe, T., Reed, J.C., Bell, M.P., McKean, D.J., Leibson, P.J., and Abraham, R.T. (1992). Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2 dependent cytotoxic T-cell line. Mol. Cell. Biol. 12, 4521-4530.
27. Kishihara, K., Penninger, J., Wallace, V., Kundig, T., Kawai, K., Wakeham, A., Timms, E., Pfeffe, r.K., Ohashi, P., Thomas, M., Furlonger, C., Paige, C., and Mak, T. (1993). Normal B lymphocyte development but impaired T cell maturation in CD45-exon 6 protein tyrosine phosphatase-deficient mice. Cell 74, 143-156.
28. Kolanus, W., Romeo, C., and Seed, B. (1993). T cell activation by clustered tyrosine kinases. Cell 74, 171-184.
29. Kong, G.H., Bu, J.Y., Kurosaki, T., Shaw, A.S., and Chan, A.C. (1995). Reconstitution of syk function by the ZAP-70 protein tyrosine kinase. Immunity 2, 485-492.
30. Koretzky, G.A., Picus, J., Thomas, M.L., and Weiss, A. (1990). Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidyl inositol pathway. Nature 346, 66-68.
31. Kurosaki, T., Takata, M., Yamanashi, Y., Inazu, T., Taniguchi, T., Yamamoto, T., and Yamamura, H. (1994). Syk activation by the Srcfamily tyrosine kinase in the B cell receptor signaling. J. Exp. Med. 179, 1725-1729.
32. Latour, S., Chow, L.M.L., and Veillette, A. (1996). Differential intrinsic enzymatic activity of Syk and ZAP-70 protein-tyrosine kinases. J. Biol. Chem. 271, 22782-22790.
33. Law, C.-L, Sidorenko, S.P., Chandran, K.A., Draves, K.E., Chan, A.C., Weiss, A., Edelhoff, S., Disteche, C.M., and Clark, E.A. (1993). Molecular characterization of human Syk. A B cell protein tyrosine kinase associated with the slgM/B cell receptor complex. J. Biol. Chem. 269, 12310-12319.
34. LoGrasso, P.V., Hawkins, J., Frank, L.J., Wisniewski, D., and Marcy, A. (1996). Mechanism of activation for ZAP-70 catalytic activity. Proc. Natl. Acad. Sci. USA 93, 12165-12170.
35. Madrenas, J., Wange, R.L., Wang, J.L., Isakov, N., Samelson, L.E., and Germain, R.N. (1995). Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agnoists. Science 267, 459-460.
36. Madrenas, J., Chau, L.A., Smith, J., Blueston, J.A., and Germain, R.N. (1997). The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. J. Exp. Med. 185, 219-229.
37. Malissen, B., and Malissen, M. (1996). Functions of TCR and pre-TCR subunits: lessons from gene ablation. Curr. Opin. Immunol. 8, 383-393.
38. Mallick-Wood, C.A., Pao, W., Cheng, A.M., Lewis, J.M., Klukarni, S., Bolen, J.B., Rowley, B., Rigelaar, R.E., Pawson, T., and Hayday, A.C. (1996). Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. Proc. Natl. Acad. Sci. USA 93, 9704-9709.
39. Meraz, M.A., White, J.-M., Sheehan, K.C., Bach, E.A., Rodig, S.J., Dighe, A.S., Kaplan, D.H., Riley, J.K., Greenlund, A.C., Campbell, D., et al. (1996). Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84, 431-442.
40. Molina, T.J., Kishihara, K., Siderovski, D.P., van Ewijk, W., Narendran, A., Timms, E., Wakeham, A., Paige, C.J., Hartmann, K.U., Veillette, A., et al. (1992). Profound block in thymocyte development in mice lacking p56lck. Nature 357, 161-164.
41. Negishi, I., Motoyama, N., Nakayama, K.-i., Nakayama, K., Senju, S., Hatakeyama, S., Zhang, Q., Chan, A.C., and Loh, D.Y. (1995). Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 376, 435-438.
42. Page, S.T., van Oers, N.S., Perlmutter, R.M., Weiss, A., and Pullen, A.M. (1997). Differential contribution of Lck and Fyn protein tyrosine kinases to intraepithelial lymphocyte development. Eur. J. Immunol. 27, 554-562.
43. lck for thymic development of transgenic γδ T cells. Science 260, 358-361.
44. Pingel, J.T., and Thomas, M.L. (1989). Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell 58, 1055-1065.
45. Rowley, R.B., Burkardt, A.L., Chao, H.-G., Matsueda, G.R., and Bolen, J.B. (1995). Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated lgα/lgβ immunoreceptor tyrosine activation motif binding and autophosphorylation. J. Biol. Chem. 270, 11590-11594.
46. Shiue, L., Zoller, M.J., and Brugge, J.S. (1995). Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem. 270, 10498-10502.
47. Sloan-Lancaster, J., Shaw, A.S., Rothbard, J.B., and Allen, P.M. (1994). Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy. Cell 79, 751-753.
48. Stein, P.L., Lee, H.-M., Rich, S., and Soriano, P. (1992). pp59fyn mutant mice display differential signaling in thymocyte and peripheral T cells. Cell 70, 741-750.
49. Straus, D., and Weiss, A. (1992). Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70, 585-593.
50. 2+ mobilization through distinct pathways. EMBO J. 13, 1341-1349.
51. Testi, R., Phillips, J.H., and Lanier, L.L. (1989). Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering: requirement for receptor crosslinking, prolonged elevation of intra-cellular [Ca2+]and stimulation of protein kinase C. J. Immunol. 142, 1854-1860.
52. Turner, M., Mee, P.J., Costello, P.S., Williams, O., Price, A.A., Duddy, L.P., Furlong, M.T., Geahlen, R.L., and Tybulewicz, V.L.J. (1995). Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 378, 298-302.
53. van Oers, N.S., von Boehmer, H., and Weiss, A. (1995). The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit. J. Exp. Med. 182, 1585-1590.
54. van Oers, N.S.C., Lowin-Kropf, B., Finlay, D., Connolly, K., and Weiss, A. (1996). αβ T cell development is abolished in mice lacking both lck and fyn protein tyrosine kinases. Immunity 5, 429-436.
55. von Boehmer, H. (1992). T cell development and selection in the thymus. Bone Marrow Transp. 9, 46-48.
56. Wiest, D.L., Ashe, J.M., Howcraft, K., Lee, H.-M., Kemper, D.M., Negishi, I., Singer, A., and Abe, R. (1997). A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity 6, 663-671.