메뉴 건너뛰기




Volumn 15, Issue 18, 1996, Pages 4862-4872

Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage

Author keywords

B cell development; Btk; Immunodeficiency; xid; XLA

Indexed keywords

CYTOPLASM PROTEIN; PROTEIN TYROSINE KINASE;

EID: 0029792213     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00867.x     Document Type: Article
Times cited : (151)

References (61)
  • 1
    • 0023513107 scopus 로고
    • Development of the primary antibody repertoire
    • Alt, F.W., Blackwell, T.K. and Yancopoulos, G.D. (1987) Development of the primary antibody repertoire. Science, 238, 1079-1087.
    • (1987) Science , vol.238 , pp. 1079-1087
    • Alt, F.W.1    Blackwell, T.K.2    Yancopoulos, G.D.3
  • 2
    • 0028151518 scopus 로고
    • Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receplor-ligated B cells
    • Aoki, Y., Isselbacher, K.J. and Pillai, S. (1994) Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receplor-ligated B cells. Proc. Natl Acad. Sci. USA, 91, 10606-10609.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10606-10609
    • Aoki, Y.1    Isselbacher, K.J.2    Pillai, S.3
  • 3
    • 0000419304 scopus 로고
    • Agammaglobulinemia
    • Bruton, O.C. (1952) Agammaglobulinemia. Pediatrics, 9, 722-728.
    • (1952) Pediatrics , vol.9 , pp. 722-728
    • Bruton, O.C.1
  • 4
    • 0025027433 scopus 로고
    • Phenotypic features and proliferative activity of B cell progenitors in X-linked agammaglobulinemia
    • Campana, D., Farrant, J., Inamidar, N., Webster, D.B. and Janossy, G. (1990) Phenotypic features and proliferative activity of B cell progenitors in X-linked agammaglobulinemia. J. Immunol., 145, 1675-1680.
    • (1990) J. Immunol. , vol.145 , pp. 1675-1680
    • Campana, D.1    Farrant, J.2    Inamidar, N.3    Webster, D.B.4    Janossy, G.5
  • 5
    • 0022354222 scopus 로고
    • B cells in patients with X-linked agammaglobulinemia
    • Conley, M.E. (1985) B cells in patients with X-linked agammaglobulinemia. J. Immunol., 134, 3070-3074.
    • (1985) J. Immunol. , vol.134 , pp. 3070-3074
    • Conley, M.E.1
  • 7
    • 0028183406 scopus 로고
    • X-linked agammaglobulinenia: New approaches to old questions based on the identification of the defective gene
    • Conley, M.E., Parolini, O., Rohrer, J. and Campana, D. (1994) X-linked agammaglobulinenia: new approaches to old questions based on the identification of the defective gene. Immunol. Rev., 138, 5-21.
    • (1994) Immunol. Rev. , vol.138 , pp. 5-21
    • Conley, M.E.1    Parolini, O.2    Rohrer, J.3    Campana, D.4
  • 9
    • 0027358430 scopus 로고
    • The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages
    • de Weers, M., Verschuren, M.C.M., Kraakman, M.E.M., Mensink, R.G.J., Schuurman, R.K.B., Van Dongen, J.J.M. and Hendriks, R.W. (1993) The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages. Eur. J. Immunol., 23, 3109-3114.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3109-3114
    • De Weers, M.1    Verschuren, M.C.M.2    Kraakman, M.E.M.3    Mensink, R.G.J.4    Schuurman, R.K.B.5    Van Dongen, J.J.M.6    Hendriks, R.W.7
  • 10
    • 0028063861 scopus 로고
    • Mutation analysis of the Bruton's tyrosine kinase gene in X-linked agammaglobulinemia: Identification of a mutation which affects the same codon as is altered in immunodeficient xid mice
    • de Weers, M., Mensink, R.G.J., Kraakman, M.E.M., Schuurman, R.K.B. and Hendriks, R.W. (1994a) Mutation analysis of the Bruton's tyrosine kinase gene in X-linked agammaglobulinemia: identification of a mutation which affects the same codon as is altered in immunodeficient xid mice. Hum. Mol. Genet., 3, 161-166.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 161-166
    • De Weers, M.1    Mensink, R.G.J.2    Kraakman, M.E.M.3    Schuurman, R.K.B.4    Hendriks, R.W.5
  • 11
    • 0028033527 scopus 로고
    • B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia
    • de Weers, M., Brouns, G.S., Hinshelwood, S., Kinnon, C., Schuurman, R.K.B., Hendriks, R.W. and Borst, J. (1994b) B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia. J. Biol. Chem., 269, 23857-23860.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23857-23860
    • De Weers, M.1    Brouns, G.S.2    Hinshelwood, S.3    Kinnon, C.4    Schuurman, R.K.B.5    Hendriks, R.W.6    Borst, J.7
  • 12
    • 0027476466 scopus 로고
    • Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development
    • Ehlich, A., Schaal, S., Gu, H., Kitamura, D., Müller, W. and Rajewski, K. (1993) Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell, 72, 695-704.
    • (1993) Cell , vol.72 , pp. 695-704
    • Ehlich, A.1    Schaal, S.2    Gu, H.3    Kitamura, D.4    Müller, W.5    Rajewski, K.6
  • 13
    • 0023109203 scopus 로고
    • Carrier detection in X-linked agammaglobulinemia by analysis of X chromosome inactivation
    • Fearon, E.R., Winkelstein, J.A., Civin, C.I., Pardoll, D.M. and Vogelstein, B. (1987) Carrier detection in X-linked agammaglobulinemia by analysis of X chromosome inactivation. N. Engl. J. Med., 316, 427-431.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 427-431
    • Fearon, E.R.1    Winkelstein, J.A.2    Civin, C.I.3    Pardoll, D.M.4    Vogelstein, B.5
  • 14
    • 0023258935 scopus 로고
    • Development of B lymphocytes in mice heterozygous for the X-linked immunodeficiency (xid) mutation
    • Forrester, L.M., Ansell, J.D. and Micklem, H.S. (1987) Development of B lymphocytes in mice heterozygous for the X-linked immunodeficiency (xid) mutation. J. Exp. Med., 165, 949-958.
    • (1987) J. Exp. Med. , vol.165 , pp. 949-958
    • Forrester, L.M.1    Ansell, J.D.2    Micklem, H.S.3
  • 15
    • 0019163003 scopus 로고
    • Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia
    • Fu, S.M., Hurley, J.N., McCune, J.M., Kunkel, H.G. and Good, R.A. (1980) Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia. J. Exp. Med., 152, 1519-1526.
    • (1980) J. Exp. Med. , vol.152 , pp. 1519-1526
    • Fu, S.M.1    Hurley, J.N.2    McCune, J.M.3    Kunkel, H.G.4    Good, R.A.5
  • 16
    • 0028580189 scopus 로고
    • Expression of Bruton's tyrosine kinase protein within the B cell lineage
    • Genevier, H.C. et al. (1994) Expression of Bruton's tyrosine kinase protein within the B cell lineage. Eur. J. Immunol., 24, 3100-3105.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3100-3105
    • Genevier, H.C.1
  • 17
    • 0025673971 scopus 로고
    • Interleukin 10, a novel B cell stimulatory factor: Unresponsiveness of X-chromosome-linked immunodeficiency B cells
    • Go, N.F., Castle, B.E., Barret, R., Kastelein, R., Dang, W., Mosmann, T.R., Moore, K.W. and Howard, M. (1990) Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X-chromosome-linked immunodeficiency B cells. J. Exp. Med., 172, 1625-1631.
    • (1990) J. Exp. Med. , vol.172 , pp. 1625-1631
    • Go, N.F.1    Castle, B.E.2    Barret, R.3    Kastelein, R.4    Dang, W.5    Mosmann, T.R.6    Moore, K.W.7    Howard, M.8
  • 18
    • 0020322129 scopus 로고
    • B-cell subpopulations identified by two-colour fluorescence analysis
    • Hardy, R.R., Hayakawa, K., Haaijman, J. and Herzenberg, L.A. (1982) B-cell subpopulations identified by two-colour fluorescence analysis. Nature, 297, 589-591.
    • (1982) Nature , vol.297 , pp. 589-591
    • Hardy, R.R.1    Hayakawa, K.2    Haaijman, J.3    Herzenberg, L.A.4
  • 19
    • 0021060430 scopus 로고
    • Demonstration of B cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence
    • Hardy, R.R., Hayakawa, K., Parks, D.R. and Herzenberg, L.A. (1983) Demonstration of B cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence. Nature, 306, 270-272.
    • (1983) Nature , vol.306 , pp. 270-272
    • Hardy, R.R.1    Hayakawa, K.2    Parks, D.R.3    Herzenberg, L.A.4
  • 20
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-B cell stages in normal mouse bone marrow
    • Hardy, R.R., Carmack, C.E., Shinton, S.A., Kemp, J.D. and Hayakawa, K. (1991) Resolution and characterization of pro-B and pre-B cell stages in normal mouse bone marrow. J. Exp. Med., 173, 1213-1225.
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 21
    • 0028158091 scopus 로고
    • B cell from CBA/N mice do not proliferate following ligation of CD40
    • Hasbold, J. and Klaus, G.G.B. (1994) B cell from CBA/N mice do not proliferate following ligation of CD40. Eur. J. Immunol., 24, 152-157.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 152-157
    • Hasbold, J.1    Klaus, G.G.B.2
  • 22
    • 0028847329 scopus 로고
    • Defective B cell development and function in Btk-deficient mice
    • Kahn, W.F. et al. (1995) Defective B cell development and function in Btk-deficient mice. Immunity, 3, 283-299.
    • (1995) Immunity , vol.3 , pp. 283-299
    • Kahn, W.F.1
  • 23
    • 0028179068 scopus 로고
    • pre-B/λ5 surrogate light chain in early hone marrow precursor B cells or normal and B cell-deficient mutant mice
    • pre-B/λ5 surrogate light chain in early hone marrow precursor B cells or normal and B cell-deficient mutant mice. Cell, 77, 133-143.
    • (1994) Cell , vol.77 , pp. 133-143
    • Karasuyama, H.1    Rolink, A.2    Shinkai, Y.3    Young, F.4    Alt, F.W.5    Melchers, F.6
  • 26
    • 0023665902 scopus 로고
    • An analysis of 5′ noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. (1987) An analysis of 5′ noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res., 15, 8125-8148.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 27
    • 0025828847 scopus 로고
    • Neutropenia associated with X-linked agammaglobulinemia
    • Kozlowski, C. and Evans, D.I.K. (1991) Neutropenia associated with X-linked agammaglobulinemia. J. Clin. Pathol., 44, 388-390.
    • (1991) J. Clin. Pathol. , vol.44 , pp. 388-390
    • Kozlowski, C.1    Evans, D.I.K.2
  • 28
    • 0027400889 scopus 로고
    • Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation
    • Lassoued, K., Nuñez, C.A., Billips, L., Kubagawa, H., Nonteiro, R.C., LeBien, T.W. and Cooper, M.D. (1993) Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation. Cell, 73, 73-86.
    • (1993) Cell , vol.73 , pp. 73-86
    • Lassoued, K.1    Nuñez, C.A.2    Billips, L.3    Kubagawa, H.4    Nonteiro, R.C.5    LeBien, T.W.6    Cooper, M.D.7
  • 29
    • 0027275497 scopus 로고
    • The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
    • Li, Y.-S., Hayakawa, K. and Hardy, R.R. (1993) The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med., 178, 951-960.
    • (1993) J. Exp. Med. , vol.178 , pp. 951-960
    • Li, Y.-S.1    Hayakawa, K.2    Hardy, R.R.3
  • 30
    • 0028906468 scopus 로고
    • Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines
    • Matsuda, T. et al. (1995) Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines. Blood, 85, 627-633.
    • (1995) Blood , vol.85 , pp. 627-633
    • Matsuda, T.1
  • 31
    • 0027183541 scopus 로고
    • PH domains: A common piece in the structural patchwork of signalling proteins
    • Musacchio, A., Gibson, T., Rice, P., Thompson, J. and Saraste, M. (1993) PH domains: a common piece in the structural patchwork of signalling proteins. Trends Biochem. Sci., 18, 343-348.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 343-348
    • Musacchio, A.1    Gibson, T.2    Rice, P.3    Thompson, J.4    Saraste, M.5
  • 33
    • 0020553009 scopus 로고
    • Unbalanced X-chromosome mosaicism in mice with X-linked immunodeficiency
    • Nahm, M.H., Paslay, W.J. and Davie, J.M. (1983) Unbalanced X-chromosome mosaicism in mice with X-linked immunodeficiency. J. Exp. Med., 158, 920-931.
    • (1983) J. Exp. Med. , vol.158 , pp. 920-931
    • Nahm, M.H.1    Paslay, W.J.2    Davie, J.M.3
  • 34
    • 0023989715 scopus 로고
    • Fluorescence-activated cell analysis and sorting of viable mammalian cells based on β-D-galactosidase activity after transduction of Escherichia coli lacZ
    • Nolan, G.P., Fiering, S., Nicolas, J.-F. and Herzenberg, L.A. (1988) Fluorescence-activated cell analysis and sorting of viable mammalian cells based on β-D-galactosidase activity after transduction of Escherichia coli lacZ. Proc. Natl Acid. Sci. USA, 85, 2603-2607.
    • (1988) Proc. Natl Acid. Sci. USA , vol.85 , pp. 2603-2607
    • Nolan, G.P.1    Fiering, S.2    Nicolas, J.-F.3    Herzenberg, L.A.4
  • 35
    • 0026586045 scopus 로고
    • The molecular and cellular basis of affinity maturation in the antibody response
    • Nossal, G.J.V. (1992) The molecular and cellular basis of affinity maturation in the antibody response. Cell, 68, 1-2.
    • (1992) Cell , vol.68 , pp. 1-2
    • Nossal, G.J.V.1
  • 36
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez, B., Michalovich, D., Bygrave, A., Ploemacher, R. and Grosveld, F. (1995) Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature, 375, 316-318.
    • (1995) Nature , vol.375 , pp. 316-318
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 37
    • 0028592706 scopus 로고
    • Genomic organization and structure of Bruton agammaglobulinemia tyrosine kinase: Localization of mutations associated with varied clinical presentations and course in X chromosome-linked agammaglobulinemia
    • Ohta, Y. et al. (1994) Genomic organization and structure of Bruton agammaglobulinemia tyrosine kinase: localization of mutations associated with varied clinical presentations and course in X chromosome-linked agammaglobulinemia. Proc. Natl Acatl. Sci. USA, 91, 9062-9066.
    • (1994) Proc. Natl Acatl. Sci. USA , vol.91 , pp. 9062-9066
    • Ohta, Y.1
  • 38
    • 0018102013 scopus 로고
    • B lymphocyte precursors in human bone marrow: An analysis of normal individuals and patients with antibody-deficiency states
    • Pearl, E.R., Vogler, L.B., Okos, A.J., Christ, W.M., Lawton, A.R., III and Cooper, M.D. (1978) B lymphocyte precursors in human bone marrow: an analysis of normal individuals and patients with antibody-deficiency states. J. Immunol., 120, 1169-1175.
    • (1978) J. Immunol. , vol.120 , pp. 1169-1175
    • Pearl, E.R.1    Vogler, L.B.2    Okos, A.J.3    Christ, W.M.4    Lawton III, A.R.5    Cooper, M.D.6
  • 39
    • 0028183398 scopus 로고
    • Bruton's tyrosine kinase is a key regulator in B cell development
    • Rawlings, D.J. and Witte, O.N. (1994) Bruton's tyrosine kinase is a key regulator in B cell development. Immunol. Rev., 138, 105-119.
    • (1994) Immunol. Rev. , vol.138 , pp. 105-119
    • Rawlings, D.J.1    Witte, O.N.2
  • 40
    • 0027305921 scopus 로고
    • Mutation of the unique region of Bruton's tyrosine kinase in immunodeficient mice
    • Rawlings, D.J. et al. (1993) Mutation of the unique region of Bruton's tyrosine kinase in immunodeficient mice. Science, 261, 358-361.
    • (1993) Science , vol.261 , pp. 358-361
    • Rawlings, D.J.1
  • 41
    • 0022386256 scopus 로고
    • B lymphocyte production in the bone marrow of mice with X-linked immunodeficiency (xid)
    • Reid, G.K. and Osmond, D.G. (1985) B lymphocyte production in the bone marrow of mice with X-linked immunodeficiency (xid). J. Immunol., 135, 2299-2302.
    • (1985) J. Immunol. , vol.135 , pp. 2299-2302
    • Reid, G.K.1    Osmond, D.G.2
  • 42
    • 0024849618 scopus 로고
    • Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice
    • Rigley, K.P., Harnett, M.M., Phillips, R.J. and Klaus, G.G.B. (1989) Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice. Eur. J. Immunol., 19, 2081-2085.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2081-2085
    • Rigley, K.P.1    Harnett, M.M.2    Phillips, R.J.3    Klaus, G.G.B.4
  • 44
    • 0025766890 scopus 로고
    • Molecular and cellular origins of B lymphocyte diversity
    • Rolink, A. and Melchers, F. (1991) Molecular and cellular origins of B lymphocyte diversity. Cell, 66, 1081-1094.
    • (1991) Cell , vol.66 , pp. 1081-1094
    • Rolink, A.1    Melchers, F.2
  • 46
    • 0028899718 scopus 로고
    • CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regulator of CD38 induced signal transduction
    • Santos-Argumedo, L., Lund, F.E., Heath, A.W., Solvason, N., Wu, W.W., Grimaldi, C., Parkhouse, R.M.E. and Howard, M. (1995) CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regulator of CD38 induced signal transduction. Int. Immunol. 7, 163-170.
    • (1995) Int. Immunol. , vol.7 , pp. 163-170
    • Santos-Argumedo, L.1    Lund, F.E.2    Heath, A.W.3    Solvason, N.4    Wu, W.W.5    Grimaldi, C.6    Parkhouse, R.M.E.7    Howard, M.8
  • 47
    • 0028060150 scopus 로고
    • Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
    • Saouaf, S.J., Mahajan, S., Rowley, R.B., Kut, S.A., Fargnoli, J., Burkhardt, A.L., Tsukada, S., Witte, O.N. and Bolen, J.B. (1994) Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc. Natl Acad. Sci. USA, 91, 9524-9528.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 9524-9528
    • Saouaf, S.J.1    Mahajan, S.2    Rowley, R.B.3    Kut, S.A.4    Fargnoli, J.5    Burkhardt, A.L.6    Tsukada, S.7    Witte, O.N.8    Bolen, J.B.9
  • 48
    • 0028114191 scopus 로고
    • IL-5 receptor-mediated lyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases
    • Sato, S. et al. (1994) IL-5 receptor-mediated lyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases. J. Exp. Med., 180, 2101-2111.
    • (1994) J. Exp. Med. , vol.180 , pp. 2101-2111
    • Sato, S.1
  • 49
    • 0023690117 scopus 로고
    • Increase of precursor frequency and clonal size of murine IgE-secreting cells by IL-4
    • Savelkoul, H.F.J., Lebman, D.A., Benner, R. and Coffman, R.L. (1988) Increase of precursor frequency and clonal size of murine IgE-secreting cells by IL-4. J. Immunol., 141, 749-755.
    • (1988) J. Immunol. , vol.141 , pp. 749-755
    • Savelkoul, H.F.J.1    Lebman, D.A.2    Benner, R.3    Coffman, R.L.4
  • 50
    • 0020017283 scopus 로고
    • The CBA/N mouse strain: An experimental model illustrating the influence of the X-chromosome on immunity
    • Scher, I. (1982) The CBA/N mouse strain: an experimental model illustrating the influence of the X-chromosome on immunity. Adv. Immunol., 33, 1-71.
    • (1982) Adv. Immunol. , vol.33 , pp. 1-71
    • Scher, I.1
  • 51
    • 0029146219 scopus 로고
    • Molecular and cellular aspects of X-linked agammaglobulinemia
    • Sideras, P. and Smith, C.I.E. (1995) Molecular and cellular aspects of X-linked agammaglobulinemia. Adv. Immunol., 59, 135-223.
    • (1995) Adv. Immunol. , vol.59 , pp. 135-223
    • Sideras, P.1    Smith, C.I.E.2
  • 52
    • 0027988170 scopus 로고
    • Genomic organization of mouse and human Bruton's agammaglobulinemia tyrosine kinase (Btk) loci
    • Sideras, P. et al. (1994) Genomic organization of mouse and human Bruton's agammaglobulinemia tyrosine kinase (Btk) loci. J. Immunol. 153, 5607-5617.
    • (1994) J. Immunol. , vol.153 , pp. 5607-5617
    • Sideras, P.1
  • 53
    • 0027369607 scopus 로고
    • ER-MP12 antigen, a new surface marker on mouse bone marrow cells with thymus-repopulating ability. I. Intrathymic repopulating ability of ER-MP12-positive bone marrow cells
    • Slieker, W.A.T , de Rijk-de Bruijn, M.F.T.R., Leenen, P.J.M. and van Ewijk, W. (1993) ER-MP12 antigen, a new surface marker on mouse bone marrow cells with thymus-repopulating ability. I. Intrathymic repopulating ability of ER-MP12-positive bone marrow cells. Int. Immunol., 5, 1093-1098.
    • (1993) Int. Immunol. , vol.5 , pp. 1093-1098
    • Slieker, W.A.T.1    De Rijk-de Bruijn, M.F.T.R.2    Leenen, P.J.M.3    Van Ewijk, W.4
  • 54
    • 0028295482 scopus 로고
    • Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells
    • Smith, C.I.E. et al. (1994) Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells. J. Immunol., 152, 557-565.
    • (1994) J. Immunol. , vol.152 , pp. 557-565
    • Smith, C.I.E.1
  • 55
    • 0021989440 scopus 로고
    • Physiology of B cells in mice with X-linked immunodeficiency. I. Size, migratory properties. and turnover of the B cell pool
    • Sprent, J., Bruce, J., Ron, Y. and Webb, S.R. (1985) Physiology of B cells in mice with X-linked immunodeficiency. I. Size, migratory properties. and turnover of the B cell pool. J. Immunol., 134, 1442-1448.
    • (1985) J. Immunol. , vol.134 , pp. 1442-1448
    • Sprent, J.1    Bruce, J.2    Ron, Y.3    Webb, S.R.4
  • 56
    • 0027261447 scopus 로고
    • Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes
    • Thomas, J.D., Sideras, P., Smith, C.I.E., Vorechovsky, I., Chapman, V. and Paul, W.E. (1993) Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science, 261, 355-358.
    • (1993) Science , vol.261 , pp. 355-358
    • Thomas, J.D.1    Sideras, P.2    Smith, C.I.E.3    Vorechovsky, I.4    Chapman, V.5    Paul, W.E.6
  • 57
    • 0027399081 scopus 로고
    • Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
    • Tsukada, S. et al. (1993) Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell, 72, 279-290.
    • (1993) Cell , vol.72 , pp. 279-290
    • Tsukada, S.1
  • 58
    • 0027441332 scopus 로고
    • The gene involved in X-linked agammaglobulinemia is a member of the src family of protein tyrosine kinases
    • Vetrie, D. et al. (1993) The gene involved in X-linked agammaglobulinemia is a member of the src family of protein tyrosine kinases. Nature, 361, 226-233.
    • (1993) Nature , vol.361 , pp. 226-233
    • Vetrie, D.1
  • 59
    • 0027941128 scopus 로고
    • Tec homology (TH) adjacent to the PH domain
    • Vihinen, M., Nilsson, L. and Smith, C.I.E. (1994) Tec homology (TH) adjacent to the PH domain. FEBS Lett., 350, 263-265.
    • (1994) FEBS Lett. , vol.350 , pp. 263-265
    • Vihinen, M.1    Nilsson, L.2    Smith, C.I.E.3
  • 61
    • 0028844632 scopus 로고
    • Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells
    • Zhou, X.Y. et al. (1995) Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells. Genes Dev., 9, 2623-2634.
    • (1995) Genes Dev. , vol.9 , pp. 2623-2634
    • Zhou, X.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.