Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice

Immunity

Volumn 7, Issue 1, 1997, Pages 155-162

  Kondo, Motonari ^a,b   Akashi, Koichi ^a   Domen, Jos ^a   Sugamura, Kazuo ^b   Weissman, Irving L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; RECEPTOR SUBUNIT; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOPOIESIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0030787787     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80518-X     Document Type: Article

References (51)

1. Akashi, K., Kondo, M., vonFreeden-Jeffry, U., Murray, R., and Weissman, I.L (1997). Bcl-2 rescues T lymphopoiesis in interleukin 7 receptor-deficient mice. Cell 89, 1033-1041.
2. Cao, X., Shores, E.W., Hu-Li, J., Anver, M.R., Kelsall, B.L., Russell, S. M., Drago, J., Noguchi, M., Grinberg, A., Bloom, E.T., et al. (1995). Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 2, 223-238.
3. Corcoran, A.E., Smart, F.M., Cowling, R.J., Crompton, T., Owen, M.J., and Venkitaraman, A.R. (1996). The interleukin-7 receptor a chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J. 15, 1924-1932.
4. Cory, S. (1995). Regulation of lymphocyte survival by the bcl-2 gene family. Annu. Rev. Immunol. 13, 513-543.
5. DiSanto, J.P., Muller, M., Guy-Grand, D., Fischer, A., and Rajewsky, K. (1995). Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl. Acad. Sci. USA 92, 377-381.
6. Fairbairn, L.J.,Cowling, G.J., Reipert, B.M., and Dexter, T.M. (1993). Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74, 823-832.
7. Fehling, H.J., Krotkova, A., Saint-Ruf, C., and von Bohmer, H. (1995). Crucial role of the pre-T-cell receptor a gene in development of αβ but not γδ T cells. Nature 375, 795-798.
8. + B cells and produces a novel growth factor affecting B and T lineage cells. Exp. Hematol. 22, 321-328.
9. Fukada, T., Hibi, M., Yamanaka, Y., Takahashi-Tezuka, M., Fujitani, Y., Yamaguchi, T., Nakajima, K., and Hirano, T. (1996). Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STATS in anti-apoptosis. Immunity 5, 449-460.
10. Fukunaga, R., Ishizaka-Ikeda, E., and Nagata, S. (1993). Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor. Cell 74, 1079-1087.
11. Giri, J.G., Ahdieh, M., Eisenman, J., Shanebeck, K., Grabstein, K., Kumaki, S., Namen, A., Park, L.S., Cosman, D., and Anderson, D. (1994). Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J. 13, 2822-2830.
12. - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150, 4244-4252.
13. Hardy, R.R., Carmack, C.E., Shinton, S.A., Kemp, J.D., and Hayakawa, K. (1991). Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213-1225.
14. + T cells, but not natural killer cells. J. Exp. Med. 184, 289-293.
15. Ihle, J. (1995). Cytokine receptor signaling. Nature 377, 591-594.
16. Karasuyama, H., Relink, A., and Melchers, F. (1996). Surrogate light chain in B cell development. Adv. Immunol. 63, 1-41.
17. Kimura, Y., Takeshita, T., Kondo, M., Ishii, N., Nakamura, M., Van Snick, J., and Sugamura, K. (1995). Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex. Int. Immunol. 7, 115-120.
18. Kinoshita, T., Yokota, T., Arai, K., and Miyajima, A. (1995). Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF receptors. EMBO J. 14, 266-275.
19. Kondo, M., Takeshita, T., Ishii, N., Nakamura, M., Watanabe, S., Arai, K., and Sugamura, K. (1993). Sharing of the interleukin-2 (IL-2) receptor γ chain between receptor for IL-2 and IL-4. Science 262, 1874-1877.
20. Kondo, M., Takeshita, T., Higuchi, M., Nakamura, M., Sudo, T., Nishikawa, S., and Sugamura, K. (1994). Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes. Science 263, 1453-1454.
21. Kündig, T.M., Schorle, H., Bachmann, M.F., Hengartner, H., Zinkernagel, R.M., and Horak, I. (1993). Immune responses in interleukin-2-deficient mice. Science 262, 1059-1061.
22. Lagasse, E., and Weissman, I.L. (1997). Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell 89, 1021-1031.
23. + stage during positive selection and promotes thymocyte differentiation at several control points. Immunity 1, 197-205.
24. MacDonnell, T.J., Deane, N., Platt, F.M., Nunez, G., Jaeger, U., McKearn, J.P., and Korsmeyer, S.J. (1989). bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57, 79-88.
25. Maki, K., Sunaga, S., Komagata, Y., Kodaira, Y., Mabuchi, A., Karasuyama, H., Yokomuro, K., Miyazaki, J.,and Ikuta, K. (1996). Interleukin 7 receptor-deficient mice lack gd T cells. Proc. Natl. Acad. Sci. USA 93, 7172-7177.
26. -/- mice. Cell 89, 1011-1019.
27. Matsuzaki, Y., Gyotoku, J., Ogawa, M., Nishikawa, S., Katsura, Y., Gachelin, G., and Nakauchi, H. (1993). Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J. Exp. Med. 178, 1283-1292.
28. Nakajima, H., Shores, E.W., Noguchi, M., and Leonard, W.J. (1997). The common cytokine receptor γ chain plays an essential role in regulating lymphoid homeostasis. J. Exp. Med. 185, 189-195.
29. Noguchi, M., Nakamura, Y., Russell, S.M., Ziegler, S.F., Tsang, M., Cao, X., and Leonard, W.J. (1993a). Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science 262, 1877-1880.
30. Noguchi, M., Yi, H., Rosenblatt, H.M., Filipovich, A.M., Adelstein, S., Modi, W.S., McBride, O.W., and Leonard, W.J. (1993b). lnterleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73, 147-157.
31. Ohbo, K., Suda, T., Hashiyama, M., Montani, A., Ikebe, M., Miyakawa, K., Moriyama, M., Nakamura, M., Katsuki, M., Takahashi, K., et al. (1996). Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor γ chain. Blood 87, 956-967.
32. Peschon, J.J., Morrissey, P.J., Grabstein, K.H., Ramsdell, F.J., Maraskovsky, E., Gliniak, B.C., Park, L.S., Ziegler, S.F., Williams, D.E., Ware, C.B., et al. (1994). Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180, 1955-1960.
33. Puck, J.M., Gesehenes, S.M., Porter, J.C., Dutra, A.S., Brown, C.J., Willard, H.F., and Henthorn, P.S. (1993). The interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1. Hum. Mol. Genet. 2, 1099-1104.
34. Reichman-Fried, M., Bosma, M.J., and Hardy, R.R. (1993). B-lineage cells in μ-transgenic seid mice proliferate in response to IL-7 but fail to show evidence of immunoglobulin light chain gene rearrangement. Int. Immunol. 5, 303-310.
35. Rodewald, H.-R., Moingeon, P., Lucich, J.L., Dosiou, C., Lopez, P., and Reinherz, E.L. (1992). A population of early fetal thymocytes expressing FcγRII/III contains precursors of T lymphocytes and natural killer cells. Cell 69, 139-150.
36. Rodewalt, H-R., Kretzschmar, K., Swat, W., and Takeda, S. (1995). Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity 3, 313-319.
37. Russell, S.M., Keegan, A.D., Harada, N., Nakamura, Y., Noguchi, M., Leland, P., Friedmann, M.C., Miyajima, A., Puri, R.K., Paul, W.E., et al. (1993). Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science 262, 1880-1883.
38. Saint-Ruf, C., Ungewiss, K., Azogui, O., Palacios, R., Owen, M.J., Hayday, A.C., and von Boehmer, H. (1994). Analysis and expression of a pre-T cell receptor gene. Science 266, 1208-1212.
39. Sherwood, P.J., and Weissman, I.L. (1990). The growth factor IL-7 induces expression of a transformation-associated antigen in normal pre-B cells. Int. Immunol. 2, 399-406.
40. Spanopoulou, E., Roman, C.A.J., Corcoran, L.M., Schlissel, M.S., Silver, D.P., Nemazee, D., Nussenzweig, M.C., Shinton, S.A., Hardy, R.R., and Baltimore, D. (1994). Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes Dev. 8, 1030-1042.
41. Strasser, A., Whittingham, S., Vaux, D.L., Bath, M.L., Adams, J.M., Cory, S., and Harris, A.W. (1991 a). Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc. Natl. Acad. Sci. USA 88, 8661-8665.
42. Strasser, A., Harris, A.W., and Cory, S. (1991b). Bcl-2 transgene inhibits T cell death and perturbs thymic self-censor ship. Cell 67, 889-899.
43. - thymocytes. J. Immunol. 146, 3068-3073.
44. Suzuki, H., Duncan, G.S., Takimoto, H., and Mak, T.W. (1997). Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain. J. Exp. Med. 185, 499-505.
45. Takeshita, T., Asao, H., Ohtani, K., Ishii, N., Kumaki, S., Tanaka, N., Munakata, H., Nakamura, M., and Sugamura, K. (1992). Cloning of the γ chain of the human IL-2 receptor. Science 257, 379-382.
46. + thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus. J. Exp. Med. 179, 145-153.
47. von Freeden-Jeffry, U., Vieira, P., Lucian, L.A., McNeil, T., Burdach, S.E.G., and Murray, R. (1995). Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181, 1519-1526.
48. Watowich, S.S., Wu, H., Socolovsky, M., Klingmuller, U., Constantinescu, S.N., and Lodish, H.F. (1996). Cytokine receptor signal transduction and the control of hematopoietic cell development. Annu. Rev. Cell Dev. Biol. 12, 91-128.
49. Wu, L., Antica, M., Johnson, G.R., Scollay, R., and Shortman, K. (1991). Developmental potential of the earliest precursor cells from the adult mouse thymus. J. Exp. Med. 174, 1617-1627.
50. Yang, E., and Korsmeyer, S.J. (1996). Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 88, 386-401.
51. Young, F., Ardman, B, Shinkai, Y., Lansford, R., Blackwell, T.K., Mendelsohn, M., Relink, A., Melchers, F., and Alt, F.W. (1994). Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation. Genes Dev. 8, 1043-1057.