Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the μ locus

International Immunology

Volumn 10, Issue 6, 1998, Pages 799-806

  Bottaro, Andrea ^a,b,e   Young, Faith ^a,b,e   Chen, Jianzhu ^a,b,f   Serwe, Matthias ^c   Sablitzky, Fred ^d   Alt, Frederick W ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^e UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Class switching; Gene targeting; IgH intronic enhancer; Matrix attachment regions

Indexed keywords

IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G; NEOMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE DELETION; GENE REARRANGEMENT; HYBRIDOMA; IMMUNOGLOBULIN GENE; INTRON; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031841548     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.6.799     Document Type: Article

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