-
1
-
-
84921929872
-
How I treat the older patient with acute myeloid leukemia
-
Ossenkoppele G, Löwenberg B. How I treat the older patient with acute myeloid leukemia. Blood. 2015;125(5):767-774.
-
(2015)
Blood
, vol.125
, Issue.5
, pp. 767-774
-
-
Ossenkoppele, G.1
Löwenberg, B.2
-
2
-
-
84878864199
-
The hallmarks of aging
-
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-1217.
-
(2013)
Cell
, vol.153
, Issue.6
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
3
-
-
0024380947
-
Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age
-
Harrison DE, Astle CM, Stone M. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol. 1989;142(11):3833-3840.
-
(1989)
J Immunol
, vol.142
, Issue.11
, pp. 3833-3840
-
-
Harrison, D.E.1
Astle, C.M.2
Stone, M.3
-
4
-
-
0029827482
-
Bone marrow transplantation in severe combined immunodeficiency from a sibling who had received a paternal bone marrow transplant
-
Stiehm ER, Roberts RL, Hanley-Lopez J, et al. Bone marrow transplantation in severe combined immunodeficiency from a sibling who had received a paternal bone marrow transplant. N Engl J Med. 1996;335(24): 1811-1814.
-
(1996)
N Engl J Med
, vol.335
, Issue.24
, pp. 1811-1814
-
-
Stiehm, E.R.1
Roberts, R.L.2
Hanley-Lopez, J.3
-
5
-
-
0020403099
-
Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure
-
Harrison DE, Astle CM. Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure. J Exp Med. 1982; 156(6):1767-1779.
-
(1982)
J Exp Med
, vol.156
, Issue.6
, pp. 1767-1779
-
-
Harrison, D.E.1
Astle, C.M.2
-
6
-
-
0018090659
-
Proliferative capacity of murine hematopoietic stem cells
-
Hellman S, Botnick LE, Hannon EC, Vigneulle RM. Proliferative capacity of murine hematopoietic stem cells. Proc Natl Acad Sci USA. 1978;75(1):490-494.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, Issue.1
, pp. 490-494
-
-
Hellman, S.1
Botnick, L.E.2
Hannon, E.C.3
Vigneulle, R.M.4
-
7
-
-
0019998021
-
Decline in bone marrow proliferative capacity as a function of age
-
Mauch P, Botnick LE, Hannon EC, Obbagy J, Hellman S. Decline in bone marrow proliferative capacity as a function of age. Blood. 1982;60(1):245-252.
-
(1982)
Blood
, vol.60
, Issue.1
, pp. 245-252
-
-
Mauch, P.1
Botnick, L.E.2
Hannon, E.C.3
Obbagy, J.4
Hellman, S.5
-
8
-
-
19944400789
-
Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice
-
Ema H, Sudo K, Seita J, et al. Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. Dev Cell. 2005;8(6):907-914.
-
(2005)
Dev Cell
, vol.8
, Issue.6
, pp. 907-914
-
-
Ema, H.1
Sudo, K.2
Seita, J.3
-
9
-
-
0020552371
-
Depletion of reserve in the hemopoietic system: III. Factors affecting the serial transplantation of bone marrow
-
Wolf NS, Priestley GV, Averill LE. Depletion of reserve in the hemopoietic system: III. Factors affecting the serial transplantation of bone marrow. Exp Hematol. 1983;11(8): 762-771.
-
(1983)
Exp Hematol
, vol.11
, Issue.8
, pp. 762-771
-
-
Wolf, N.S.1
Priestley, G.V.2
Averill, L.E.3
-
10
-
-
84855507486
-
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
-
Dykstra B, Olthof S, Schreuder J, Ritsema M, de Haan G. Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. J Exp Med. 2011;208(13): 2691-2703.
-
(2011)
J Exp Med
, vol.208
, Issue.13
, pp. 2691-2703
-
-
Dykstra, B.1
Olthof, S.2
Schreuder, J.3
Ritsema, M.4
De Haan, G.5
-
11
-
-
0025281056
-
Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice
-
Van Zant G, Holland BP, Eldridge PW, Chen JJ. Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice. J Exp Med. 1990; 171(5):1547-1565.
-
(1990)
J Exp Med
, vol.171
, Issue.5
, pp. 1547-1565
-
-
Van Zant, G.1
Holland, B.P.2
Eldridge, P.W.3
Chen, J.J.4
-
12
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
Rossi DJ, Bryder D, Zahn JM, et al. Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci USA. 2005;102(26):9194-9199.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.26
, pp. 9194-9199
-
-
Rossi, D.J.1
Bryder, D.2
Zahn, J.M.3
-
13
-
-
0034613690
-
Age-associated characteristics of murine hematopoietic stem cells
-
Sudo K, Ema H, Morita Y, Nakauchi H. Age-associated characteristics of murine hematopoietic stem cells. J Exp Med. 2000;192(9): 1273-1280.
-
(2000)
J Exp Med
, vol.192
, Issue.9
, pp. 1273-1280
-
-
Sudo, K.1
Ema, H.2
Morita, Y.3
Nakauchi, H.4
-
14
-
-
84886924368
-
Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding
-
Verovskaya E, Broekhuis MJ, Zwart E, et al. Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood. 2013;122(4):523-532.
-
(2013)
Blood
, vol.122
, Issue.4
, pp. 523-532
-
-
Verovskaya, E.1
Broekhuis, M.J.2
Zwart, E.3
-
15
-
-
0029813378
-
The aging of hematopoietic stem cells
-
Morrison SJ, Wandycz AM, Akashi K, Globerson A, Weissman IL. The aging of hematopoietic stem cells. Nat Med. 1996; 2(9):1011-1016.
-
(1996)
Nat Med.
, vol.2
, Issue.9
, pp. 1011-1016
-
-
Morrison, S.J.1
Wandycz, A.M.2
Akashi, K.3
Globerson, A.4
Weissman, I.L.5
-
17
-
-
85041354223
-
In the hematopoietic stem cell hierarchy
-
in the hematopoietic stem cell hierarchy. Blood. 2001;98(10):2966-2972.
-
(2001)
Blood
, vol.98
, Issue.10
, pp. 2966-2972
-
-
-
18
-
-
77950418688
-
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
-
Beerman I, Bhattacharya D, Zandi S, et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci USA. 2010;107(12):5465-5470.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.12
, pp. 5465-5470
-
-
Beerman, I.1
Bhattacharya, D.2
Zandi, S.3
-
19
-
-
0021341845
-
Studies of hematopoietic stem cells spared by 5-fluorouracil
-
Van Zant G. Studies of hematopoietic stem cells spared by 5-fluorouracil. J Exp Med. 1984;159(3):679-690.
-
(1984)
J Exp Med
, vol.159
, Issue.3
, pp. 679-690
-
-
Van Zant, G.1
-
20
-
-
0030914867
-
Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
-
Bradford GB, Williams B, Rossi R, Bertoncello I. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp Hematol. 1997;25(5):445-453.
-
(1997)
Exp Hematol
, vol.25
, Issue.5
, pp. 445-453
-
-
Bradford, G.B.1
Williams, B.2
Rossi, R.3
Bertoncello, I.4
-
21
-
-
0032980506
-
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
-
Cheshier SH, Morrison SJ, Liao X, Weissman IL. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci USA. 1999; 96(6):3120-3125.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.6
, pp. 3120-3125
-
-
Cheshier, S.H.1
Morrison, S.J.2
Liao, X.3
Weissman, I.L.4
-
22
-
-
34547692981
-
Long-term propagation of distinct hematopoietic differentiation programs in vivo
-
Dykstra B, Kent D, Bowie M, et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell. 2007;1(2):218-229.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.2
, pp. 218-229
-
-
Dykstra, B.1
Kent, D.2
Bowie, M.3
-
23
-
-
77953512588
-
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
-
Morita Y, Ema H, Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med. 2010;207(6):1173-1182.
-
(2010)
J Exp Med
, vol.207
, Issue.6
, pp. 1173-1182
-
-
Morita, Y.1
Ema, H.2
Nakauchi, H.3
-
24
-
-
84995962623
-
Hematopoietic stem cells count and remember self-renewal divisions
-
Bernitz JM, Kim HS, MacArthur B, Sieburg H, Moore K. Hematopoietic stem cells count and remember self-renewal divisions. Cell. 2016;167(5):1296-1309.
-
(2016)
Cell
, vol.167
, Issue.5
, pp. 1296-1309
-
-
Bernitz, J.M.1
Kim, H.S.2
MacArthur, B.3
Sieburg, H.4
Moore, K.5
-
25
-
-
0030891634
-
Alternatives to stem cell renewal from a developmental viewpoint
-
Van Zant G, de Haan G, Rich IN. Alternatives to stem cell renewal from a developmental viewpoint. Exp Hematol. 1997;25(3): 187-192.
-
(1997)
Exp Hematol
, vol.25
, Issue.3
, pp. 187-192
-
-
Van Zant, G.1
De Haan, G.2
Rich, I.N.3
-
26
-
-
84994784751
-
Do hematopoietic stem cells get old?
-
Jung JJ, Buisman SC, de Haan G. Do hematopoietic stem cells get old? Leukemia. 2017;31(3):529-531.
-
(2017)
Leukemia
, vol.31
, Issue.3
, pp. 529-531
-
-
Jung, J.J.1
Buisman, S.C.2
De Haan, G.3
-
27
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM. Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc Natl Acad Sci USA. 1994;91(21):9857-9860.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.21
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
28
-
-
79955951566
-
Age-related changes in human hematopoietic stem/progenitor cells
-
Kuranda K, Vargaftig J, de la Rochere P, et al. Age-related changes in human hematopoietic stem/progenitor cells. Aging Cell. 2011; 10(3):542-546.
-
(2011)
Aging Cell
, vol.10
, Issue.3
, pp. 542-546
-
-
Kuranda, K.1
Vargaftig, J.2
de la Rochere, P.3
-
29
-
-
84055200841
-
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
-
Pang WW, Price EA, Sahoo D, et al. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci USA. 2011; 108(50):20012-20017.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.50
, pp. 20012-20017
-
-
Pang, W.W.1
Price, E.A.2
Sahoo, D.3
-
30
-
-
84978086032
-
Human and murine hematopoietic stem cell aging is associated with functional impairments and intrinsic megakaryocytic/erythroid bias
-
Rundberg Nilsson A, Soneji S, Adolfsson S, Bryder D, Pronk CJ. Human and murine hematopoietic stem cell aging is associated with functional impairments and intrinsic megakaryocytic/erythroid bias. PLoS One. 2016;11(7):e0158369.
-
(2016)
PLoS One
, vol.11
, Issue.7
-
-
Nilsson, R.A.1
Soneji, S.2
Adolfsson, S.3
Bryder, D.4
Pronk, C.J.5
-
31
-
-
0032919858
-
Genetic analysis of hemopoietic cell cycling in mice suggests its involvement in organismal life span
-
De Haan G, Van Zant G. Genetic analysis of hemopoietic cell cycling in mice suggests its involvement in organismal life span. FASEB J. 1999;13(6):707-713.
-
(1999)
FASEB J
, vol.13
, Issue.6
, pp. 707-713
-
-
De Haan, G.1
Van Zant, G.2
-
32
-
-
0030743240
-
Intrinsic and extrinsic control of hemopoietic stem cell numbers: Mapping of a stem cell gene
-
de Haan G, Van Zant G. Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene. J Exp Med. 1997;186(4):529-536.
-
(1997)
J Exp Med
, vol.186
, Issue.4
, pp. 529-536
-
-
De Haan, G.1
Van Zant, G.2
-
33
-
-
47049099198
-
A new mechanism for the aging of hematopoietic stem cells: Aging changes the clonal composition of the stem cell compartment but not individual stem cells
-
Cho RH, Sieburg HB, Muller-Sieburg CE. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood. 2008;111(12):5553-5561.
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5553-5561
-
-
Cho, R.H.1
Sieburg, H.B.2
Muller-Sieburg, C.E.3
-
34
-
-
85015223506
-
Autophagy maintains the metabolism and function of young and old stem cells
-
Ho TT, Warr MR, Adelman ER, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543(7644):205-210.
-
(2017)
Nature
, vol.543
, Issue.7644
, pp. 205-210
-
-
Ho, T.T.1
Warr, M.R.2
Adelman, E.R.3
-
35
-
-
84940446838
-
Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations
-
Wilson NK, Kent DG, Buettner F, et al. Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations. Cell Stem Cell. 2015;16(6):712-724.
-
(2015)
Cell Stem Cell
, vol.16
, Issue.6
, pp. 712-724
-
-
Wilson, N.K.1
Kent, D.G.2
Buettner, F.3
-
36
-
-
84962229210
-
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
-
Grover A, Sanjuan-Pla A, Thongjuea S, et al. Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. Nat Commun. 2016;7:11075.
-
(2016)
Nat Commun.
, vol.7
, pp. 11075
-
-
Grover, A.1
Sanjuan-Pla, A.2
Thongjuea, S.3
-
37
-
-
84956599311
-
Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
-
Kowalczyk MS, Tirosh I, Heckl D, et al. Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. Genome Res. 2015;25(12):1860-1872.
-
(2015)
Genome Res.
, vol.25
, Issue.12
, pp. 1860-1872
-
-
Kowalczyk, M.S.1
Tirosh, I.2
Heckl, D.3
-
38
-
-
77957939097
-
Systemic signals regulate ageing and rejuvenation of blood stem cell niches
-
article
-
Mayack SR, Shadrach JL, Kim FS, Wagers AJ. Systemic signals regulate ageing and rejuvenation of blood stem cell niches [article retracted in Nature. 2010;467(7317):872].
-
(2010)
Retracted in Nature
, vol.467
, Issue.7317
, pp. 872
-
-
Mayack, S.R.1
Shadrach, J.L.2
Kim, F.S.3
Wagers, A.J.4
-
39
-
-
75749090492
-
-
Nature. 2010;463(7280):495-500.
-
(2010)
Nature
, vol.463
, Issue.7280
, pp. 495-500
-
-
-
40
-
-
84900338737
-
Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors
-
Katsimpardi L, Litterman NK, Schein PA, et al. Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors. Science. 2014;344(6184):630-634.
-
(2014)
Science
, vol.344
, Issue.6184
, pp. 630-634
-
-
Katsimpardi, L.1
Litterman, N.K.2
Schein, P.A.3
-
41
-
-
84877816844
-
Heterochronic parabiosis: Historical perspective and methodological considerations for studies of aging and longevity
-
Conboy MJ, Conboy IM, Rando TA. Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity. Aging Cell. 2013;12(3):525-530.
-
(2013)
Aging Cell
, vol.12
, Issue.3
, pp. 525-530
-
-
Conboy, M.J.1
Conboy, I.M.2
Rando, T.A.3
-
42
-
-
84902075251
-
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
-
Villeda SA, Plambeck KE, Middeldorp J, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med. 2014;20(6): 659-663.
-
(2014)
Nat Med
, vol.20
, Issue.6
, pp. 659-663
-
-
Villeda, S.A.1
Plambeck, K.E.2
Middeldorp, J.3
-
43
-
-
85018326953
-
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
-
Castellano JM, Mosher KI, Abbey RJ, et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544(7651):488-492.
-
(2017)
Nature
, vol.544
, Issue.7651
, pp. 488-492
-
-
Castellano, J.M.1
Mosher, K.I.2
Abbey, R.J.3
-
44
-
-
85006121567
-
Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment
-
Kovtonyuk LV, Fritsch K, Feng X, Manz MG, Takizawa H. Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment. Front Immunol. 2016;7:502.
-
(2016)
Front Immunol.
, vol.7
, pp. 502
-
-
Kovtonyuk, L.V.1
Fritsch, K.2
Feng, X.3
Manz, M.G.4
Takizawa, H.5
-
45
-
-
84858649330
-
Rantes/ Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
-
Ergen AV, Boles NC, Goodell MA. Rantes/ Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood. 2012;119(11):2500-2509.
-
(2012)
Blood
, vol.119
, Issue.11
, pp. 2500-2509
-
-
Ergen, A.V.1
Boles, N.C.2
Goodell, M.A.3
-
46
-
-
84994400050
-
Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia
-
Zambetti NA, Ping Z, Chen S, et al. Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia. Cell Stem Cell. 2016;19(5):613-627.
-
(2016)
Cell Stem Cell
, vol.19
, Issue.5
, pp. 613-627
-
-
Zambetti, N.A.1
Ping, Z.2
Chen, S.3
-
47
-
-
84876909069
-
The ageing haematopoietic stem cell compartment
-
Geiger H, de Haan G, Florian MC. The ageing haematopoietic stem cell compartment. Nat Rev Immunol. 2013;13(5):376-389.
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.5
, pp. 376-389
-
-
Geiger, H.1
De Haan, G.2
Florian, M.C.3
-
48
-
-
34250017413
-
Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment
-
Ju Z, Jiang H, Jaworski M, et al. Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment. Nat Med. 2007; 13(6):742-747.
-
(2007)
Nat Med
, vol.13
, Issue.6
, pp. 742-747
-
-
Ju, Z.1
Jiang, H.2
Jaworski, M.3
-
49
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 2007;447(7145):725-729.
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
50
-
-
84857769403
-
Telomere length is associated with disease severity and declines with age in dyskeratosis congenita
-
Alter BP, Rosenberg PS, Giri N, Baerlocher GM, Lansdorp PM, Savage SA. Telomere length is associated with disease severity and declines with age in dyskeratosis congenita. Haematologica. 2012;97(3):353-359.
-
(2012)
Haematologica
, vol.97
, Issue.3
, pp. 353-359
-
-
Alter, B.P.1
Rosenberg, P.S.2
Giri, N.3
Baerlocher, G.M.4
Lansdorp, P.M.5
Savage, S.A.6
-
51
-
-
84928569602
-
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
-
Walter D, Lier A, Geiselhart A, et al. Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature. 2015;520(7548):549-552.
-
(2015)
Nature
, vol.520
, Issue.7548
, pp. 549-552
-
-
Walter, D.1
Lier, A.2
Geiselhart, A.3
-
52
-
-
84883428326
-
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
-
Yamamoto R, Morita Y, Ooehara J, et al. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell. 2013; 154(5):1112-1126.
-
(2013)
Cell
, vol.154
, Issue.5
, pp. 1112-1126
-
-
Yamamoto, R.1
Morita, Y.2
Ooehara, J.3
-
53
-
-
84906254220
-
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
-
Flach J, Bakker ST, Mohrin M, et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014;512(7513):198-202.
-
(2014)
Nature
, vol.512
, Issue.7513
, pp. 198-202
-
-
Flach, J.1
Bakker, S.T.2
Mohrin, M.3
-
54
-
-
84937904208
-
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
-
Steensma DP, Bejar R, Jaiswal S, et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood. 2015;126(1):9-16.
-
(2015)
Blood
, vol.126
, Issue.1
, pp. 9-16
-
-
Steensma, D.P.1
Bejar, R.2
Jaiswal, S.3
-
55
-
-
42149185640
-
Telomeres and aging
-
Aubert G, Lansdorp PM. Telomeres and aging. Physiol Rev. 2008;88(2):557-579.
-
(2008)
Physiol Rev
, vol.88
, Issue.2
, pp. 557-579
-
-
Aubert, G.1
Lansdorp, P.M.2
-
56
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph KL, Chang S, Lee HW, et al. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell. 1999; 96(5):701-712.
-
(1999)
Cell
, vol.96
, Issue.5
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
-
57
-
-
0345636016
-
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells
-
Allsopp RC, Morin GB, Horner JW, DePinho R, Harley CB, Weissman IL. Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med. 2003;9(4):369-371.
-
(2003)
Nat Med.
, vol.9
, Issue.4
, pp. 369-371
-
-
Allsopp, R.C.1
Morin, G.B.2
Horner, J.W.3
DePinho, R.4
Harley, C.B.5
Weissman, I.L.6
-
58
-
-
84949555897
-
Cellular senescence in aging and age-related disease: From mechanisms to therapy
-
Childs BG, Durik M, Baker DJ, van Deursen JM. Cellular senescence in aging and age-related disease: from mechanisms to therapy. Nat Med. 2015;21(12):1424-1435.
-
(2015)
Nat Med
, vol.21
, Issue.12
, pp. 1424-1435
-
-
Childs, B.G.1
Durik, M.2
Baker, D.J.3
van Deursen, J.M.4
-
59
-
-
84958093401
-
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan
-
Baker DJ, Childs BG, Durik M, et al. Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature. 2016;530(7589): 184-189.
-
(2016)
Nature
, vol.530
, Issue.7589
, pp. 184-189
-
-
Baker, D.J.1
Childs, B.G.2
Durik, M.3
-
60
-
-
67349161638
-
Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence
-
Attema JL, Pronk CJ, Norddahl GL, Nygren JM, Bryder D. Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence. Oncogene. 2009; 28(22):2238-2243.
-
(2009)
Oncogene
, vol.28
, Issue.22
, pp. 2238-2243
-
-
Attema, J.L.1
Pronk, C.J.2
Norddahl, G.L.3
Nygren, J.M.4
Bryder, D.5
-
61
-
-
84954218515
-
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
-
Chang J, Wang Y, Shao L, et al. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nat Med. 2016;22(1):78-83.
-
(2016)
Nat Med.
, vol.22
, Issue.1
, pp. 78-83
-
-
Chang, J.1
Wang, Y.2
Shao, L.3
-
62
-
-
84860634046
-
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation
-
Florian MC, Dörr K, Niebel A, et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell. 2012; 10(5):520-530.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.5
, pp. 520-530
-
-
Florian, M.C.1
Dörr, K.2
Niebel, A.3
-
63
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 2006;12(4):446-451.
-
(2006)
Nat Med.
, vol.12
, Issue.4
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
-
64
-
-
84925265469
-
Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging
-
Mohrin M, Shin J, Liu Y, et al. Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging. Science. 2015;347(6228): 1374-1377.
-
(2015)
Science
, vol.347
, Issue.6228
, pp. 1374-1377
-
-
Mohrin, M.1
Shin, J.2
Liu, Y.3
-
65
-
-
79955698235
-
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging
-
Norddahl GL, Pronk CJ, Wahlestedt M, et al. Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. Cell Stem Cell. 2011;8(5):499-510.
-
(2011)
Cell Stem Cell
, vol.8
, Issue.5
, pp. 499-510
-
-
Norddahl, G.L.1
Pronk, C.J.2
Wahlestedt, M.3
-
66
-
-
33344469959
-
The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga LM, Bystrykh LV, de Boer A, et al. The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood. 2006;107(5):2170-2179.
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 2170-2179
-
-
Kamminga, L.M.1
Bystrykh, L.V.2
De Boer, A.3
-
67
-
-
10344258563
-
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
-
Iwama A, Oguro H, Negishi M, et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity. 2004;21(6): 843-851.
-
(2004)
Immunity
, vol.21
, Issue.6
, pp. 843-851
-
-
Iwama, A.1
Oguro, H.2
Negishi, M.3
-
68
-
-
0033569427
-
Functional antagonism of the polycomb-group genes eed and Bmi1 in hemopoietic cell proliferation
-
Lessard J, Schumacher A, Thorsteinsdottir U, van Lohuizen M, Magnuson T, Sauvageau G. Functional antagonism of the polycomb-group genes eed and Bmi1 in hemopoietic cell proliferation. Genes Dev. 1999;13(20): 2691-2703.
-
(1999)
Genes Dev
, vol.13
, Issue.20
, pp. 2691-2703
-
-
Lessard, J.1
Schumacher, A.2
Thorsteinsdottir, U.3
Van Lohuizen, M.4
Magnuson, T.5
Sauvageau, G.6
-
69
-
-
77956282774
-
Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells
-
Majewski IJ, Ritchie ME, Phipson B, et al. Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood. 2010;116(5):731-739.
-
(2010)
Blood
, vol.116
, Issue.5
, pp. 731-739
-
-
Majewski, I.J.1
Ritchie, M.E.2
Phipson, B.3
-
70
-
-
84876485242
-
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
-
Klauke K, Radulović V, Broekhuis M, et al. Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol. 2013;15(4):353-362.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.4
, pp. 353-362
-
-
Klauke, K.1
Radulović, V.2
Broekhuis, M.3
-
71
-
-
65049086788
-
Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression
-
Noda S, Ichikawa H, Miyoshi H. Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression. Biochem Biophys Res Commun. 2009;383(2):210-215.
-
(2009)
Biochem Biophys Res Commun
, vol.383
, Issue.2
, pp. 210-215
-
-
Noda, S.1
Ichikawa, H.2
Miyoshi, H.3
-
72
-
-
84880203894
-
An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state
-
Wahlestedt M, Norddahl GL, Sten G, et al. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. Blood. 2013;121(21): 4257-4264.
-
(2013)
Blood
, vol.121
, Issue.21
, pp. 4257-4264
-
-
Wahlestedt, M.1
Norddahl, G.L.2
Sten, G.3
-
73
-
-
84875965163
-
Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging
-
Beerman I, Bock C, Garrison BS, et al. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell. 2013;12(4):413-425.
-
(2013)
Cell Stem Cell
, vol.12
, Issue.4
, pp. 413-425
-
-
Beerman, I.1
Bock, C.2
Garrison, B.S.3
-
74
-
-
84899768899
-
Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
-
Sun D, Luo M, Jeong M, et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 2014; 14(5):673-688.
-
(2014)
Cell Stem Cell
, vol.14
, Issue.5
, pp. 673-688
-
-
Sun, D.1
Luo, M.2
Jeong, M.3
-
75
-
-
34548208677
-
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
-
Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol. 2007;5(8):e201.
-
(2007)
PLoS Biol
, vol.5
, Issue.8
-
-
Chambers, S.M.1
Shaw, C.A.2
Gatza, C.3
Fisk, C.J.4
Donehower, L.A.5
Goodell, M.A.6
-
76
-
-
85027442392
-
Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly
-
Zink F, Stacey SN, Norddahl GL, et al. Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly. Blood. 2017;130(6):742-752.
-
(2017)
Blood
, vol.130
, Issue.6
, pp. 742-752
-
-
Zink, F.1
Stacey, S.N.2
Norddahl, G.L.3
-
77
-
-
84930003179
-
Age-related mutations associated with clonal hematopoietic expansion and malignancies
-
Xie M, Lu C, Wang J, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med. 2014;20(12):1472-1478.
-
(2014)
Nat Med
, vol.20
, Issue.12
, pp. 1472-1478
-
-
Xie, M.1
Lu, C.2
Wang, J.3
-
78
-
-
84920053873
-
Age-related clonal hematopoiesis associated with adverse outcomes
-
Jaiswal S, Fontanillas P, Flannick J, et al. Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med. 2014; 371(26):2488-2498.
-
(2014)
N Engl J Med
, vol.371
, Issue.26
, pp. 2488-2498
-
-
Jaiswal, S.1
Fontanillas, P.2
Flannick, J.3
-
79
-
-
84920024296
-
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
-
Genovese G, Kähler AK, Handsaker RE, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N Engl J Med. 2014;371(26):2477-2487.
-
(2014)
N Engl J Med
, vol.371
, Issue.26
, pp. 2477-2487
-
-
Genovese, G.1
Kähler, A.K.2
Handsaker, R.E.3
-
80
-
-
84921468426
-
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
-
Mayle A, Yang L, Rodriguez B, et al. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood. 2015;125(4):629-638.
-
(2015)
Blood
, vol.125
, Issue.4
, pp. 629-638
-
-
Mayle, A.1
Yang, L.2
Rodriguez, B.3
-
81
-
-
0029901946
-
Nonrandom X-inactivation patterns in normal females: Lyonization ratios vary with age
-
Busque L, Mio R, Mattioli J, et al. Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age. Blood. 1996; 88(1):59-65.
-
(1996)
Blood
, vol.88
, Issue.1
, pp. 59-65
-
-
Busque, L.1
Mio, R.2
Mattioli, J.3
-
82
-
-
0030800389
-
Clonal hae-mopoiesis in normal elderly women: Implications for the myeloproliferative disorders and myelodysplastic syndromes
-
Champion KM, Gilbert JG, Asimakopoulos FA, Hinshelwood S, Green AR. Clonal hae-mopoiesis in normal elderly women: implications for the myeloproliferative disorders and myelodysplastic syndromes. Br J Hae-matol. 1997;97(4):920-926.
-
(1997)
Br J Hae-Matol
, vol.97
, Issue.4
, pp. 920-926
-
-
Champion, K.M.1
Gilbert, J.G.2
Asimakopoulos, F.A.3
Hinshelwood, S.4
Green, A.R.5
-
83
-
-
84961821536
-
Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2
-
van den Akker EB, Pitts SJ, Deelen J, et al.; Genome of The Netherlands Consortium. Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2. Blood. 2016;127(11):1512-1515.
-
(2016)
Blood
, vol.127
, Issue.11
, pp. 1512-1515
-
-
van den Akker, E.B.1
Pitts, S.J.2
Deelen, J.3
-
84
-
-
84983379414
-
Molecular mechanisms of erythrocyte aging
-
Hoehn RS, Jernigan PL, Chang AL, Edwards MJ, Pritts TA. Molecular mechanisms of erythrocyte aging. Biol Chem. 2015;396(6-7): 621-631.
-
(2015)
Biol Chem.
, vol.396
, Issue.6-7
, pp. 621-631
-
-
Hoehn, R.S.1
Jernigan, P.L.2
Chang, A.L.3
Edwards, M.J.4
Pritts, T.A.5
-
85
-
-
85010198872
-
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
-
Fuster JJ, MacLauchlan S, Zuriaga MA, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355(6327): 842-847.
-
(2017)
Science
, vol.355
, Issue.6327
, pp. 842-847
-
-
Fuster, J.J.1
MacLauchlan, S.2
Zuriaga, M.A.3
-
86
-
-
85023756316
-
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
-
Jaiswal S, Natarajan P, Silver AJ, et al. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease. N Engl J Med. 2017; 377(2):111-121.
-
(2017)
N Engl J Med
, vol.377
, Issue.2
, pp. 111-121
-
-
Jaiswal, S.1
Natarajan, P.2
Silver, A.J.3
-
87
-
-
84861985190
-
Counting stem cells: Methodological constraints
-
Bystrykh LV, Verovskaya E, Zwart E, Broekhuis M, de Haan G. Counting stem cells: methodological constraints. Nat Methods. 2012;9(6):567-574.
-
(2012)
Nat Methods
, vol.9
, Issue.6
, pp. 567-574
-
-
Bystrykh, L.V.1
Verovskaya, E.2
Zwart, E.3
Broekhuis, M.4
De Haan, G.5
-
88
-
-
0021692767
-
Haemopoiesis by clonal succession?
-
Rosendaal M, Adam J. Haemopoiesis by clonal succession? Blood Cells. 1984;10(2-3): 473-485.
-
(1984)
Blood Cells
, vol.10
, Issue.2-3
, pp. 473-485
-
-
Rosendaal, M.1
Adam, J.2
-
89
-
-
0030021624
-
Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism
-
Prchal JT, Prchal JF, Belickova M, et al. Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism. J Exp Med. 1996;183(2): 561-567.
-
(1996)
J Exp Med
, vol.183
, Issue.2
, pp. 561-567
-
-
Prchal, J.T.1
Prchal, J.F.2
Belickova, M.3
-
90
-
-
79951698622
-
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
-
Takizawa H, Regoes RR, Boddupalli CS, Bonhoeffer S, Manz MG. Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. J Exp Med. 2011;208(2):273-284.
-
(2011)
J Exp Med
, vol.208
, Issue.2
, pp. 273-284
-
-
Takizawa, H.1
Regoes, R.R.2
Boddupalli, C.S.3
Bonhoeffer, S.4
Manz, M.G.5
-
91
-
-
11244302345
-
Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization
-
Roeder I, Kamminga LM, Braesel K, Dontje B, de Haan G, Loeffler M. Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization. Blood. 2005;105(2):609-616.
-
(2005)
Blood
, vol.105
, Issue.2
, pp. 609-616
-
-
Roeder, I.1
Kamminga, L.M.2
Braesel, K.3
Dontje, B.4
De Haan, G.5
Loeffler, M.6
-
92
-
-
80054719497
-
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding
-
Lu R, Neff NF, Quake SR, Weissman IL. Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol. 2011;29(10):928-933.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.10
, pp. 928-933
-
-
Lu, R.1
Neff, N.F.2
Quake, S.R.3
Weissman, I.L.4
-
93
-
-
77950981309
-
Cellular barcoding tool for clonal analysis in the hematopoietic system
-
Gerrits A, Dykstra B, Kalmykowa OJ, et al. Cellular barcoding tool for clonal analysis in the hematopoietic system. Blood. 2010; 115(13):2610-2618.
-
(2010)
Blood
, vol.115
, Issue.13
, pp. 2610-2618
-
-
Gerrits, A.1
Dykstra, B.2
Kalmykowa, O.J.3
-
94
-
-
84876297531
-
Diverse and heritable lineage imprinting of early haematopoietic progenitors
-
Naik SH, Perié L, Swart E, et al. Diverse and heritable lineage imprinting of early haematopoietic progenitors. Nature. 2013; 496(7444):229-232.
-
(2013)
Nature
, vol.496
, Issue.7444
, pp. 229-232
-
-
Naik, S.H.1
Perié, L.2
Swart, E.3
-
95
-
-
84888212251
-
Analysis of the clonal growth and differentiation dynamics of primitive bar-coded human cord blood cells in NSG mice
-
Cheung AM, Nguyen LV, Carles A, et al. Analysis of the clonal growth and differentiation dynamics of primitive bar-coded human cord blood cells in NSG mice. Blood. 2013;122(18):3129-3137.
-
(2013)
Blood
, vol.122
, Issue.18
, pp. 3129-3137
-
-
Cheung, A.M.1
Nguyen, L.V.2
Carles, A.3
-
96
-
-
84908125658
-
Clonal dynamics of native haematopoiesis
-
Sun J, Ramos A, Chapman B, et al. Clonal dynamics of native haematopoiesis. Nature. 2014;514(7522):322-327.
-
(2014)
Nature
, vol.514
, Issue.7522
, pp. 322-327
-
-
Sun, J.1
Ramos, A.2
Chapman, B.3
-
97
-
-
84924038121
-
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
-
Busch K, Klapproth K, Barile M, et al. Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature. 2015;518(7540):542-546.
-
(2015)
Nature
, vol.518
, Issue.7540
, pp. 542-546
-
-
Busch, K.1
Klapproth, K.2
Barile, M.3
-
98
-
-
85014043886
-
Epigenetic memory underlies cell-autonomous heterogeneous behavior of hematopoietic stem cells
-
published correction
-
Yu VW, Yusuf RZ, Oki T, et al. Epigenetic memory underlies cell-autonomous heterogeneous behavior of hematopoietic stem cells [published correction appears in Cell. 2017;168(5):944-945].
-
(2016)
Cell
, vol.168
, Issue.5
, pp. 944-945
-
-
Yu, V.W.1
Yusuf, R.Z.2
Oki, T.3
-
100
-
-
84996605620
-
Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development
-
Henninger J, Santoso B, Hans S, et al. Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nat Cell Biol. 2017;19(1): 17-27.
-
(2017)
Nat Cell Biol.
, vol.19
, Issue.1
, pp. 17-27
-
-
Henninger, J.1
Santoso, B.2
Hans, S.3
-
101
-
-
84880548336
-
The intestinal crypt, a prototype stem cell compartment
-
Clevers H. The intestinal crypt, a prototype stem cell compartment. Cell. 2013;154(2): 274-284.
-
(2013)
Cell
, vol.154
, Issue.2
, pp. 274-284
-
-
Clevers, H.1
-
102
-
-
84991669713
-
Tissue-specific mutation accumulation in human adult stem cells during life
-
Blokzijl F, de Ligt J, Jager M, et al. Tissue-specific mutation accumulation in human adult stem cells during life. Nature. 2016; 538(7624):260-264.
-
(2016)
Nature
, vol.538
, Issue.7624
, pp. 260-264
-
-
Blokzijl, F.1
De Ligt, J.2
Jager, M.3
-
103
-
-
73049116186
-
Lgr5(1ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker N, Huch M, Kujala P, et al. Lgr5(1ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. 2010;6(1):25-36.
-
(2010)
Cell Stem Cell
, vol.6
, Issue.1
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
-
104
-
-
84957869951
-
Replacement of lost Lgr5-positive stem cells through plasticity of their enterocyte-lineage daughters
-
Tetteh PW, Basak O, Farin HF, et al. Replacement of lost Lgr5-positive stem cells through plasticity of their enterocyte-lineage daughters. Cell Stem Cell. 2016;18(2): 203-213.
-
(2016)
Cell Stem Cell
, vol.18
, Issue.2
, pp. 203-213
-
-
Tetteh, P.W.1
Basak, O.2
Farin, H.F.3
-
105
-
-
84899527626
-
Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors
-
Riddell J, Gazit R, Garrison BS, et al. Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors [published correction appears in Cell. 2014;158(1):226]. Cell. 2014; 157(3):549-564.
-
(2014)
Cell
, vol.158
, Issue.3
, pp. 226
-
-
Riddell, J.1
Gazit, R.2
Garrison, B.S.3
-
106
-
-
84899527626
-
Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors
-
published correction Cell. 2014;158(1):226
-
Cell. 2014; 157(3):549-564.
-
(2014)
Cell
, vol.157
, Issue.3
, pp. 549-564
-
-
Riddell, J.1
Gazit, R.2
Garrison, B.S.3
-
107
-
-
84881149632
-
Induction of a hemogenic program in mouse fibroblasts
-
Pereira CF, Chang B, Qiu J, et al. Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell. 2013;13(2):205-218.
-
(2013)
Cell Stem Cell
, vol.13
, Issue.2
, pp. 205-218
-
-
Pereira, C.F.1
Chang, B.2
Qiu, J.3
-
108
-
-
84978857997
-
Ectopic miR-125a expression induces long-term repopulating stem cell capacity in mouse and human hematopoietic progenitors
-
Wojtowicz EE, Lechman ER, Hermans KG, et al. Ectopic miR-125a expression induces long-term repopulating stem cell capacity in mouse and human hematopoietic progenitors. Cell Stem Cell. 2016;19(3): 383-396.
-
(2016)
Cell Stem Cell
, vol.19
, Issue.3
, pp. 383-396
-
-
Wojtowicz, E.E.1
Lechman, E.R.2
Hermans, K.G.3
-
109
-
-
34548852838
-
Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia
-
Signer RA, Montecino-Rodriguez E, Witte ON, McLaughlin J, Dorshkind K. Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia. Blood. 2007;110(6):1831-1839.
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 1831-1839
-
-
Signer, R.A.1
Montecino-Rodriguez, E.2
Witte, O.N.3
McLaughlin, J.4
Dorshkind, K.5
-
110
-
-
84949036093
-
Stem cells and healthy aging
-
Goodell MA, Rando TA. Stem cells and healthy aging. Science. 2015;350(6265): 1199-1204.
-
(2015)
Science
, vol.350
, Issue.6265
, pp. 1199-1204
-
-
Goodell, M.A.1
Rando, T.A.2
-
111
-
-
85013408064
-
Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate
-
Wahlestedt M, Erlandsson E, Kristiansen T, et al. Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate. Nat Commun. 2017;8:14533.
-
(2017)
Nat Commun
, vol.8
, pp. 14533
-
-
Wahlestedt, M.1
Erlandsson, E.2
Kristiansen, T.3
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