Heterochronic parabiosis: Historical perspective and methodological considerations for studies of aging and longevity

Aging Cell

Volumn 12, Issue 3, 2013, Pages 525-530

  Conboy, Michael J ^a,b   Conboy, Irina M ^a,b   Rando, Thomas A ^c,d  

^a University of California at Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

Aging; Anti aging; Heterochronic studies; Longevity; Mice; Parabiosis

Indexed keywords

CELL AGING; CELL REGENERATION; CELL SURVIVAL; HEMATOPOIESIS; HISTORY; IMMUNE SYSTEM; IMMUNOPATHOLOGY; INTESTINE EPITHELIUM; LIFESPAN; LONGEVITY; NONHUMAN; PARABIOSIS; POSTOPERATIVE CARE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; STEM CELL; SURGICAL MORTALITY;

AGE FACTORS; AGING; ANIMALS; CELL AGING; LONGEVITY; PARABIOSIS; STEM CELLS;

ANIMALIA; MUS;

EID: 84877816844     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12065     Document Type: Review

References (34)

1. Andresen RH, Hass GM, Madden DA, Monroe CW (1957) Postparabiotic tissue reactions of rabbits to musculofascial cross-transplants. J. Exp. Med. 105, 85-92.
2. Anonymous (1886) Obituary - Paul Bert. Boston Med. Sur. J. 115, 485.
3. Bert P (1864) Expériences et Considérations Sur la Greffe Animale. J. Anatomie Physiologie 1, 69-87.
4. Binhammer RR, Schneider M, Finerty JC (1953) Time as a factor in postirradiation protection by parabiosis. Am. J. Physiol. 175, 440-442.
5. Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA (2007) Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317, 807-810.
6. Bunster E, Meyer RK (1933) An improved method of parabiosis. Anat. Rec. 57, 339-343.
7. Butenko GM (1990) [Active mechanisms of dysfunction in the process of aging]. Vestn. Akad. Med. Nauk SSSR 2, 0-23.
8. Butenko GM, Gubrii IB (1980) [Primary immune response in parabionts of different ages]. Biull. Eksp. Biol. Med. 89, 435-437.
9. Butenko GM, Gubrii IB (1981) [Mechanism of immune response inhibition during parabiosis of animals of different ages]. Biull. Eksp. Biol. Med. 92, 318-319.
10. Carlson ME, Hsu M, Conboy IM (2008) Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 454, 528-532.
11. Carrel A (1913) Concerning Visceral Organisms. J. Exp. Med. 18, 155-161.
12. Carroll HW, Kimeldorf DJ (1967) Protection through parabiosis against the lethal effects of exposure to large doses of x-rays. Science 156, 954-955.
13. Carroll HW, Kimeldorf DJ (1969) Mechanisms of protection against gastrointestinal and hematopoietic radiation lethality by parabiosis. Radiat. Res. 39, 770-776.
14. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433, 760-764.
15. Conboy MJ, Conboy IM (2009) Parabiosis in aging research and regenerative medicine. In Methods in Bioengineering: Stem Cell Bioengineering. (Parekkadan B, Yarmush M, eds). Norwood, MA: Artech House, pp. 125-142.
16. Finerty J (1952) Parabiosis in physiological studies. Physiol. Rev. 32, 277-302.
17. Finerty JC, Panos TC (1951) Parabiosis intoxication. Proc. Soc. Exp. Biol. Med. 76, 833-835.
18. Finerty JC, Binhammer R, Schneider M (1952) Protection of irradiated rats by parabiosis. Tex. Rep. Biol. Med. 10, 496-500.
19. Frol'kis VV, Paramonova GI, Shaposhnikov VM (1996) [Effect of heterochronic parabiosis on liver microsomal enzyme oxidation]. Dokl. Akad. Nauk 347, 828-830.
20. Gubrii IB, Reznikov AG, Demchenko VN, Butenko GM (1987) [Cessation of ovarian cycles in a young mouse while in parabiosis with an older one]. Biull. Eksp. Biol. Med. 103, 205-208.
21. Hall CE, Hall O, Nevis AH (1959) Prolongation of survival by parabiosis in strain 129 dystrophic mice. Am. J. Physiol. 196, 110-112.
22. Hilgard HR, Cornelius EA, Dalmasso AP, Martinez C, Good RA (1964) Immune mechanisms in parabiosis intoxication. J. Exp. Med. 119, 567-579.
23. Hruza Z (1971) Increase of cholesterol turnover of old rats connected by parabiosis with young rats. Exp. Gerontol. 6, 103-107.
24. Ludwig FC, Elashoff RM (1972) Mortality in syngeneic rat parabionts of different chronological age. Trans. NY Acad. Sci. 34, 582-587.
25. Lunsford WR, McCay CM, Lupien PJ, Pope FE, Sperling G (1963) Parabiosis as a method for studying factors which affect aging in rats. Gerontologia 7, 1-8.
26. McCay CM, Pope F, Lunsford W, Sperling G, Sambhavaphol P (1957) Parabiosis between old and young rats. Gerontologia 1, 7-17.
27. Nisbet NW (1973) Parabiosis in immunobiology. Transplant. Rev. 15, 123-161.
28. Pope F, Lunsford W, McCay CM (1956) Experimental prolongation of the life span. J. Chronic. Dis. 4, 153-158.
29. Rando TA, Chang HY (2012) Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell 148, 46-57.
30. Sauerbruch R, Heyde M (1908) Ueber Parabiose kunstlich vereinigter Warmbliiter. Munch. Med Wchnschr. 55, 153-156.
31. Schmidt G (1922) Stand und Ziele der Parabioseforschung, auf Grund eigener Untersuchungen. Deutsche Ztschr. F. Chir. 171, 141-156.
32. Sidorenko AV, Gubrii IB, Andrianova LF, Macsijuk TV, Butenko GM (1986) Functional rearrangement of lymphohemopoietic system in heterochronically parabiosed mice. Mech. Ageing Dev. 36, 41-56.
33. Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T (2011) The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90-94.
34. Warren S, Chute RN, Farrington EM (1960) Protection of the hematopoietic system by parabiosis. Lab. Invest. 9, 191-198.