Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice

Blood

Volumn 122, Issue 18, 2013, Pages 3129-3137

  Cheung, Alice M S ^a,b   Nguyen, Long V ^a   Carles, Annaick ^c   Beer, Philip ^a   Miller, Paul H ^a   Knapp, David J H F ^a   Dhillon, Kiran ^a   Hirst, Martin ^a,c   Eaves, Connie J ^a,c  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; INTERLEUKIN 2 RECEPTOR GAMMA;

ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW BIOPSY; BONE MARROW CELL; CELL CLONE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINEAGE; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE SEQUENCE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LENTIVIRINAE; LYMPHOID CELL; MOLECULAR DYNAMICS; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 84888212251     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-06-508432     Document Type: Article

References (37)

1. Doulatov S, Notta F, Laurenti E, Dick JE. Hematopoiesis: a human perspective. Cell Stem Cell. 2012;10(2):120-136.
2. Bhatia M, Wang JC, Kapp U, Bonnet D, Dick JE. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc Natl Acad Sci USA. 1997;94(10):5320-5325.
3. Conneally E, Cashman J, Petzer A, Eaves C. Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proc Natl Acad Sci USA. 1997;94(18):9836-9841.
4. Muller-Sieburg CE, Sieburg HB. Clonal diversity of the stem cell compartment. Curr Opin Hematol. 2006;13(4):243-248.
5. Jordan CT, Lemischka IR. Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes Dev. 1990;4(2):220-232.
6. Schmidt M, Zickler P, Hoffmann G, et al. Polyclonal long-term repopulating stem cell clones in a primate model. Blood. 2002;100(8):2737-2743.
7. Kiem HP, Sellers S, Thomasson B, et al. Longterm clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia. Mol Ther. 2004;9(3):389-395.
8. Glimm H, Schmidt M, Fischer M, et al. Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients. Blood. 2005;106(3):893-898.
9. Lu R, Neff NF, Quake SR, Weissman IL. Tracking single hematopoietic stem cells in vivo using highthroughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol. 2011;29(10):928-933.
10. Gerrits A, Dykstra B, Kalmykowa OJ, et al. Cellular barcoding tool for clonal analysis in the hematopoietic system. Blood. 2010;115(13):2610-2618.
11. Verovskaya E, Broekhuis MJ, Zwart E, Ritsema M, Van Os R, De Haan G, Bystrykh LV. Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood. 2013;122(4):523-532.
12. Grosselin J, Sii-Felice K, Payen E, Chretien S, Roux DT, Leboulch P. Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics. Stem Cells. 2013.
13. Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science. 1996;273(5272):242-245.
14. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121(7):1109-1121.
15. Benz C, Copley MR, Kent DG, et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell. 2012;10(3):273-283.
16. Shultz LD, Brehm MA, Garcia-Martinez JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012;12(11):786-798.
17. Notta F, Doulatov S, Laurenti E, Poeppl A, Jurisica I, Dick JE. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science. 2011;333(6039):218-221.
18. Björgvinsdóttir H, Bryder D, Sitnicka E, et al. Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach. Hum Gene Ther. 2002;13(9):1061-1073.
19. Leurs C, Jansen M, Pollok KE, et al. Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD341 cord blood cells. Hum Gene Ther. 2003;14(6):509-519.
20. Ando K, Yahata T, Sato T, et al. Direct evidence for ex vivo expansion of human hematopoietic stem cells. Blood. 2006;107(8):3371-3377.
21. McKenzie JL, Gan OI, Doedens M, Wang JC, Dick JE. Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment. Nat Immunol. 2006;7(11):1225-1233.
22. Schepers K, Swart E, Van Heijst JW, et al. Dissecting T cell lineage relationships by cellular barcoding. J Exp Med. 2008;205(10):2309-2318.
23. Bystrykh LV, Verovskaya E, Zwart E, Broekhuis M, De Haan G. Counting stem cells: methodological constraints. Nat Methods. 2012;9(6):567-574.
24. Logan AC, Nightingale SJ, Haas DL, Cho GJ, Pepper KA, Kohn DB. Factors influencing the titer and infectivity of lentiviral vectors. Hum Gene Ther. 2004;15(10):976-988.
25. Wiegand KC, Shah SP, Al-Agha OM, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med. 2010;363(16):1532- 1543.
26. Dykstra B, Kent D, Bowie M, et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell. 2007;1(2):218-229.
27. Cho RH, Sieburg HB, Muller-Sieburg CE. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood. 2008;111(12):5553-5561.
28. Boitano AE, Wang J, Romeo R, et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science. 2010;329(5997):1345-1348.
29. Wright DE, Wagers AJ, Gulati AP, Johnson FL, Weissman IL. Physiological migration of hematopoietic stem and progenitor cells. Science. 2001;294(5548):1933-1936.
30. Glimm H, Eisterer W, Lee K, et al. Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice. J Clin Invest. 2001;107(2):199-206.
31. Mazurier F, Doedens M, Gan OI, Dick JE. Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nat Med. 2003;9(7):959-963.
32. Majeti R, Park CY, Weissman IL. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell. 2007;1(6):635-645.
33. Liu C, Chen BJ, Deoliveira D, Sempowski GD, Chao NJ, Storms RW. Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation. Blood. 2010;116(25):5518-5527.
34. Zanjani ED, Flake AW, Rice H, Hedrick M, Tavassoli M. Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep. J Clin Invest. 1994;93(3):1051-1055.
35. Cheung AM, Leung D, Rostamirad S, et al. Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation. Blood. 2012;119(15):3431-3439.
36. Benveniste P, Frelin C, Janmohamed S, et al. Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. Cell Stem Cell. 2010;6(1):48-58.
37. Sloma I, Beer PA, Saw KM, et al. Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia. Exp Hematol. 2013.