Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Lagrange, Brice ^a   Benaoudia, Sacha ^a   Wallet, Pierre ^a   Magnotti, Flora ^a   Provost, Angelina ^a   Michal, Fanny ^a   Martin, Amandine ^a   Di Lorenzo, Flaviana ^b   Py, Bénédicte F ^a   Molinaro, Antonio ^b   Henry, Thomas ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; CASPASE 4; GUANINE NUCLEOTIDE BINDING PROTEIN; INFLAMMASOME; LIPID A; LIPOPOLYSACCHARIDE; CASP11 PROTEIN, MOUSE; CASP4 PROTEIN, HUMAN; CASPASE; CRYOPYRIN; INITIATOR CASPASE;

CELL COMPONENT; GENE EXPRESSION; LIPID; POLYSACCHARIDE; PROTEIN; RODENT;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; FRANCISELLA NOVICIDA; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; PYROPTOSIS; ACYLATION; ANIMAL; C57BL MOUSE; CELL CULTURE; FRANCISELLA; GENETICS; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; RNA INTERFERENCE; SPECIES DIFFERENCE; U-937 CELL LINE;

BACTERIA (MICROORGANISMS); FRANCISELLA; FRANCISELLA TULARENSIS SUBSP. NOVICIDA; MURINAE; MUS;

ACYLATION; ANIMALS; CASPASES; CASPASES, INITIATOR; CELLS, CULTURED; CYTOSOL; FRANCISELLA; HUMANS; INFLAMMASOMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RNA INTERFERENCE; SPECIES SPECIFICITY; U937 CELLS;

EID: 85040834658     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02682-y     Document Type: Article

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