Human NLRP3 Inflammasome senses multiple types of bacterial RNAs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 45, 2014, Pages 16059-16064

  Sha, Wenwen ^a,b   Mitoma, Hiroki ^b,c   Hanabuchi, Shino ^b,d   Bao, Musheng ^b,d   Weng, Leiyun ^b   Sugimoto, Naoshi ^b,e   Liu, Ying ^b,f   Zhang, Zhiqiang ^a,b,g   Zhong, Jin ^a   Sun, Bing ^a   Liu, Yong Jun ^a,b,d  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^c KYUSHU UNIVERSITY HOSPITAL   (Japan)

^d MEDIMMUNE   (United States)

^e KYOTO UNIVERSITY   (Japan)

^f INSTITUTE OF BIOPHYSICS   (China)

^g HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

Bacterial RNA; Innate immunity; Nlrp3 inflammasome; Primary macrophages; Single stranded rna

Indexed keywords

BACTERIAL RNA; CRYOPYRIN; DOUBLE STRANDED RNA; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; POLYINOSINIC POLYCYTIDYLIC ACID; POLYURIDYLIC ACID; RIBONUCLEASE III; RIBOSOME RNA; RNA 16S; RNA 23S; RNA 5S; TRANSFER RNA; CARRIER PROTEIN; IL1B PROTEIN, HUMAN; NLRP3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN SECONDARY STRUCTURE; ANIMAL; CYTOLOGY; IMMUNOLOGY; SPECIES DIFFERENCE; TUMOR CELL LINE;

ANIMALS; CARRIER PROTEINS; CELL LINE, TUMOR; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; MACROPHAGES; MICE; RNA, BACTERIAL; RNA, MESSENGER; SPECIES SPECIFICITY;

EID: 84909595118     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412487111     Document Type: Article

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