A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Nature Genetics

Volumn 49, Issue 10, 2017, Pages 1437-1449

  Peters, Lauren A ^a,b   Perrigoue, Jacqueline ^c   Mortha, Arthur ^a,d   Iuga, Alina ^e   Song, Won Min ^a   Neiman, Eric M ^c   Llewellyn, Sean R ^a   Di Narzo, Antonio ^a   Kidd, Brian A ^a   Telesco, Shannon E ^c   Zhao, Yongzhong ^a   Stojmirovic, Aleksandar ^c   Sendecki, Jocelyn ^c   Shameer, Khader ^a   Miotto, Riccardo ^a   Losic, Bojan ^a   Shah, Hardik ^a   Lee, Eunjee ^a   Wang, Minghui ^a   Faith, Jeremiah J ^a   Kasarskis, Andrew ^a   Brodmerkel, Carrie ^c   Curran, Mark ^c   Das, Anuk ^c   Friedman, Joshua R ^c   Fukui, Yoshinori ^f   Humphrey, Mary Beth ^g   Iritani, Brian M ^h   Sibinga, Nicholas ⁱ   Tarrant, Teresa K ^j,k   Argmann, Carmen ^a   Hao, Ke ^a   Roussos, Panos ^a   Zhu, Jun ^a,b   Zhang, Bin ^a   Dobrin, Radu ^c,l   Mayer, Lloyd F ^a   Schadt, Eric E ^a,b   more..

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b A Mount Sinai Venture ^*  (United States)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d UNIVERSITY OF TORONTO   (Canada)

^e Department of Medicine   (United States)

^f KYUSHU UNIVERSITY   (Japan)

^g UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^j UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF NORTH CAROLINA   (United States)

^l BRISTOL MYERS SQUIBB   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLOGRAFT INFLAMMATORY FACTOR 1; C REACTIVE PROTEIN; CALGRANULIN; CRYOPYRIN; DEDICATOR OF CYTOKINESIS 2; DOWNSTREAM OF KINASE 3; G PROTEIN SIGNALING MODULATOR 3; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LACTOFERRIN; MITOGEN ACTIVATED PROTEIN KINASE; NCK ASSOCIATED PROTEIN 1 LIKE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; SMALL INTERFERING RNA; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CROHN DISEASE; FUNCTIONAL GENOMICS; GENE IDENTIFICATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; HUMAN TISSUE; INFLAMMATORY BOWEL DISEASE; MACROPHAGE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; ULCERATIVE COLITIS; ADOPTIVE TRANSFER; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CAUSALITY; CELL CULTURE; CHEMICALLY INDUCED; COLITIS; DISEASE MODEL; FEMALE; GENE REGULATORY NETWORK; GENE SILENCING; GENETIC PREDISPOSITION; GENOMICS; INFORMATION PROCESSING; INTESTINE; KNOCKOUT MOUSE; MALE; METABOLISM; PROCEDURES; REGULATOR GENE; T LYMPHOCYTE SUBPOPULATION; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; CAUSALITY; CELLS, CULTURED; COLITIS; DATASETS AS TOPIC; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; GENES, REGULATOR; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, GENETIC; RNA, SMALL INTERFERING; T-LYMPHOCYTE SUBSETS; TRANSCRIPTOME;

EID: 85030166718     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3947     Document Type: Article

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