Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

PLoS Biology

Volumn 4, Issue 2, 2006, Pages 186-199

  Weiner, Orion D ^a,e   Rentel, Maike C ^b   Ott, Alex ^b   Brown, Glenn E ^c   Jedrychowski, Mark ^a   Yaffe, Michael B ^c   Gygi, Steven P ^a   Cantley, Lewis C ^d   Bourne, Henry R ^b   Kirschner, Marc W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; F ACTIN; HEMATOPOIETIC PROTEIN 1; MYOSIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN DERIVATIVE; PROTEIN INHIBITOR; RAC PROTEIN; RHO FACTOR; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; WISKOTT ALDRICH SYNDROME PROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 2; HEM PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; POLYPHOSPHOINOSITIDE; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; WASF2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL POLARITY; CHEMOTAXIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN FAMILY; PROTEIN POLYMERIZATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; ENZYME ACTIVATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NEUTROPHIL; NOMENCLATURE; PHOSPHORYLATION; PROTEIN BINDING;

ANIMALIA;

ACTINS; ANIMALS; CELL LINE; CELL POLARITY; CHEMOTAXIS; ENZYME ACTIVATION; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MYOSINS; NEUTROPHILS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SUBUNITS; RAC GTP-BINDING PROTEINS; REACTIVE OXYGEN SPECIES; TERMINOLOGY; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 33244492872     PISSN: 15457885     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0040038     Document Type: Article

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