G protein signaling modulator-3 inhibits the inflammasome activity of NLRP3

Journal of Biological Chemistry

Volumn 289, Issue 48, 2014, Pages 33245-33257

  Giguère, Patrick M ^a   Gall, Bryan J ^b   Ezekwe, Ejiofor A D ^a   Laroche, Geneviève ^a   Buckley, Brian K ^a   Kebaier, Chahnaz ^a   Wilson, Justin E ^a   Ting, Jenny P ^a   Siderovski, David P ^b   Duncan, Joseph A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BODY FLUIDS; CHEMICAL ACTIVATION; PHYSIOLOGY;

CYSTEINE PROTEINASE; HEMATOPOIETIC LINEAGE; LEUCINE-RICH REPEATS; MULTI-PROTEIN COMPLEX; NEGATIVE REGULATORS; NOD-LIKE RECEPTORS; TRANSCRIPTIONAL ACTIVATIONS; YEAST TWO HYBRID;

PROTEINS;

CRYOPYRIN; G PROTEIN SIGNALING MODULATOR 3; GUANINE NUCLEOTIDE BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ALUMINUM POTASSIUM SULFATE; ALUMINUM SULFATE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; G18 PROTEIN, MOUSE; GPSM3 PROTEIN, HUMAN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; IL1B PROTEIN, HUMAN; IL1B PROTEIN, MOUSE; IMMUNOLOGICAL ADJUVANT; NLRP3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MOUSE; NLRP3 GENE; NONHUMAN; PRO IL 1 GENE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; CHEMICALLY INDUCED; GENETICS; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PERITONITIS; PROTEIN TERTIARY STRUCTURE;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; CARRIER PROTEINS; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HEK293 CELLS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; PERITONITIS; PROTEIN STRUCTURE, TERTIARY;

EID: 84912134538     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.578393     Document Type: Article

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