The Dok-3/Grb2 protein signal module attenuates lyn kinase-dependent activation of syk kinase in b cell antigen receptor microclusters

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2303-2313

  Lösing, Marion ^a,e   Goldbeck, Ingo ^a,f   Manno, Birgit ^a   Oellerich, Thomas ^a,g   Schnyder, Tim ^b   Bohnenberger, Hanibal ^a   Stork, Björn ^a,h   Urlaub, Henning ^c,d   Batista, Facundo D ^b   Wienands, Jürgen ^a   Engelke, Michael ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^e Vivo Science GmbH   (Germany)

^f Richter Helm BioLogics   (Germany)

^g GOETHE UNIVERSITY   (Germany)

^h HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTER PROTEINS; B CELL ANTIGEN RECEPTORS; GROWTH FACTOR; MICRO-CLUSTERS; SIGNAL INTEGRATION; SITE-SPECIFIC;

ANTIGENS; CELL MEMBRANES; PHOSPHORYLATION; PROTEINS; SUGARS;

ENZYMES;

ADAPTOR PROTEIN; B CELL ANTIGEN RECEPTOR; DOWNSTREAM OF KINASE 3; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INOSITOL PHOSPHATE; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN SH2; UNCLASSIFIED DRUG;

ARTICLE; ATTENUATION; B LYMPHOCYTE ACTIVATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACIDS; ANIMALS; CALCIUM; CALCIUM SIGNALING; CHICKENS; ENZYME ACTIVATION; GRB2 ADAPTOR PROTEIN; HUMANS; LYMPHOCYTE ACTIVATION; MASS SPECTROMETRY; MICROSCOPY, CONFOCAL; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84873805760     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.406546     Document Type: Article

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