DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation

Journal of Immunology

Volumn 193, Issue 2, 2014, Pages 840-848

  Kim, Susana Soo Yeon ^a,b   Lee, Koon Guan ^b   Chin, Ching Siang ^b   Ng, Say Kong ^b   Pereira, Natasha Ann ^b   Xu, Shengli ^b   Lam, Kong Peng ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; BRUTON TYROSINE KINASE; INTERFERON REGULATORY FACTOR 3; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN DOK3; PROTEIN KINASE; TANK BINDING KINASE 1; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLUENZA; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; GENE EXPRESSION; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; ORTHOMYXOVIRIDAE; PHOSPHORYLATION; POLY I-C; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 3; TOLL-LIKE RECEPTOR 3;

EID: 84904263872     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301601     Document Type: Article

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