Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

Molecular Systems Biology

Volumn 8, Issue , 2012, Pages

  Wang, I Ming ^a   Zhang, Bin ^b,c   Yang, Xia ^c,d   Zhu, Jun ^b,c   Stepaniants, Serguei ^e   Zhang, Chunsheng ^a   Meng, Qingying ^d   Peters, Mette ^c   He, Yudong ^f   Ni, Chester ^g   Slipetz, Deborah ^a   Crackower, Michael A ^a   Houshyar, Hani ^a   Tan, Christopher M ^a   Asante Appiah, Ernest ^a   O'Neill, Gary ^a   Jane Luo, Mingjuan ^h   Thieringer, Rolf ^a   Yuan, Jeffrey ^a   Chiu, Chi Sung ^a   Yee Lum, Pek ⁱ   Lamb, John ^j   Boie, Yves ^k   Wilkinson, Hilary A ^a   Schadt, Eric E ^b,c   Dai, Hongyue ^a   Roberts, Christopher ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c SAGE BIONETWORKS   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Covance Genomics Laboratory ^*  (United States)

^f AMGEN INC   (United States)

^g BENAROYA RESEARCH INSTITUTE   (United States)

^h ELI LILLY AND COMPANY   (United States)

ⁱ Ayasdi Inc   (United States)

^j PFIZER INC   (United States)

^k BROAD INSTITUTE OF MIT AND HARVARD   (United States)

more..

Author keywords

Bayesian network; co expression network; inflammatome; inflammatory diseases; key regulators

Indexed keywords

INFLAMMASOME; CASPASE; CHEMOKINE; INTERLEUKIN DERIVATIVE; SIGNAL PEPTIDE;

ARTICLE; BAYES THEOREM; GENE EXPRESSION PROFILING; NONHUMAN; PRIORITY JOURNAL; RODENT DISEASE; SYSTEM ANALYSIS; AGE; ANALYSIS OF VARIANCE; ANIMAL; BAGG ALBINO MOUSE; BIOLOGY; C57BL MOUSE; COHORT ANALYSIS; DISEASE MODEL; FEMALE; GENE REGULATORY NETWORK; GENETICS; HUMAN; IMMUNOLOGY; MALE; METABOLISM; METHODOLOGY; MOUSE; MOUSE MUTANT; RAT; SEX DIFFERENCE; SPRAGUE DAWLEY RAT;

RODENTIA;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; BAYES THEOREM; CASPASES; CHEMOKINES; COHORT STUDIES; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; INFLAMMASOMES; INTERLEUKINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS;

EID: 84864208657     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2012.24     Document Type: Article

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