Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 22, 2015, Pages 7061-7066

  Harbour, Stacey N ^a   Maynard, Craig L ^a   Zindl, Carlene L ^a   Schoeb, Trenton R ^b   Weaver, Casey T ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Colitis; Th1; Th17

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 23; STAT4 PROTEIN; TOLL LIKE RECEPTOR 5; TRANSCRIPTION FACTOR T BET; STAT4 PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; HISTOPATHOLOGY; LAMINA PROPRIA; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; WEIGHT REDUCTION; ANIMAL; CYTOLOGY; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASE; KNOCKOUT MOUSE; METABOLISM; NONPARAMETRIC TEST; PATHOPHYSIOLOGY;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; INFLAMMATORY BOWEL DISEASES; INTERFERON-GAMMA; MICE; MICE, KNOCKOUT; STAT4 TRANSCRIPTION FACTOR; STATISTICS, NONPARAMETRIC; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH17 CELLS;

EID: 84930679365     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1415675112     Document Type: Article

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