DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

Journal of Immunology

Volumn 193, Issue 11, 2014, Pages 5660-5667

  Watanabe, Mayuki ^a   Terasawa, Masao ^a   Miyano, Kei ^b   Yanagihara, Toyoshi ^a   Uruno, Takehito ^a   Sanematsu, Fumiyuki ^a   Nishikimi, Akihiko ^c   Côté, Jean François ^d   Sumimoto, Hideki ^b   Fukui, Yoshinori ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; DOCK2 PROTEIN; DOCK5 PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAC PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; 4-(3'-(2'-CHLOROPHENYL)-2'-PROPEN-1'-YLIDENE)-1-PHENYL-3,5-PYRAZOLIDINEDIONE; DOCK2 PROTEIN, MOUSE; DOCK5 PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PYRAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL EXTRACELLULAR TRAP; NONHUMAN; PROTEIN FUNCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMOTAXIS; DRUG EFFECTS; EXTRACELLULAR TRAP; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOLECULARLY TARGETED THERAPY; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; CHEMOTAXIS; EXTRACELLULAR TRAPS; GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR TARGETED THERAPY; NEUTROPHILS; OXIDATION-REDUCTION; PYRAZOLES; RAC GTP-BINDING PROTEINS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84912557831     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400885     Document Type: Article

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