Inherited DOCK2 deficiency in patients with early-onset invasive infections

New England Journal of Medicine

Volumn 372, Issue 25, 2015, Pages 2409-2422

  Dobbs, Kerry ^a   Conde, Cecilia Domínguez ^f   Zhang, Shen Ying ^i,k,l   Parolini, Silvia ^d,o   Audry, Magali ⁱ   Chou, Janet ^a   Haapaniemi, Emma ^g,q   Keles, Sevgi ^a,x   Bilic, Ivan ^f   Okada, Satoshi ⁱ   Massaad, Michel J ^a   Rounioja, Samuli ^l,v,w   Alwahadneh, Adel M ^m,z   Serwas, Nina K ^f   Capuder, Kelly ^a   Çiftçi, Ergin ^y   Felgentreff, Kerstin ^a   Ohsumi, Toshiro K ^c   Pedergnana, Vincent ^k   Boisson, Bertrand ⁱ   Haskoloʇlu, Şule ^u,z   Ensari, Arzu ^v,aa   Schuster, Michael ^f   Moretta, Alessandro ^p   Itan, Yuval ⁱ   Patrizi, Ornella ^o   Rozenberg, Flore ^l   Lebon, Pierre ^l   Saarela, Janna ^r   Knip, Mikael ^s,t,u,v   Petrovski, Slavé ^j,ac,ae   Goldstein, David B ^j,ac   Parrott, Roberta E ^ad,af   Savas, Berna ^aa   Schambach, Axel ^ab   Tabellini, Giovanna ^o   Bock, Christoph ^f   Chatila, Talal A ^a   Comeau, Anne Marie ^e   Geha, Raif S ^a   Abel, Laurent ^k,l   Buckley, Rebecca H ^z,ad,af   Ikincioʇullari, Aydan ^z   Al Herz, Waleed ^z,ag   Helminen, Merja ^v   Doʇu, Figen ^z   Casanova, Jean Laurent ^k,l,m,n   Boztuʇ, Kaan ^f,g,h   Notarangelo, Luigi D ^a,b,d   more..

^a New England Regl Primate Res C   (United States)

^b Manton Center for Orphan Disease Research   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^g UNIV KLIN KINDER JUGENDHEILKUNDE   (Austria)

^h MEDICAL UNIVERSITY OF VIENNA   (Austria)

ⁱ St Giles Laboratory of Human Genetics of Infectious Disease Rockefeller Branch Rockefeller University   (United States)

^j Och Spine at New York Presbyterian Hospitals   (United States)

^k IMAGINE INSTITUTE   (France)

^l UNIVERSITÉ PARIS DESCARTES   (France)

^m HÔPITAL NECKER ENFANTS MALADES   (France)

ⁿ HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^o UNIVERSITY OF BRESCIA   (Italy)

^p UNIVERSITY OF GENOA   (Italy)

^q FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^r Institute for Molecular Medicine Finland   (Finland)

^s UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^t Research Programs Unit Diabetes and Obesity Research Program   (Finland)

^u FOLKHÄLSAN RESEARCH CENTER   (Finland)

^v UNIVERSITY OF HELSINKI   (Finland)

^w FIMLAB LABORATORIES   (Finland)

^x TAMPERE UNIVERSITY HOSPITAL   (Finland)

^y NECMETTIN ERBAKAN UNIVERSITY   (Turkey)

^z Department of Pediatric Infectious Disease ^*  (United States)

^aa Immunology and Allergy   (Turkey)

^ab ANKARA UNIVERSITY   (Turkey)

^ac KING HUSSEIN MEDICAL CENTER   (Jordan)

^ad HANNOVER MEDICAL SCHOOL   (Germany)

^ae DUKE UNIVERSITY   (United States)

^af Division of Allergy and Immunology   (United States)

^ag DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; ALPHA INTERFERON; ALPHA2B INTERFERON; AMYLASE; BCG VACCINE; BUSULFAN; CHEMOKINE; CHICKENPOX VACCINE; COTRIMOXAZOLE; DEDICATOR OF CYTOKINESIS 2 PROTEIN; FLUDARABINE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PHYTOHEMAGGLUTININ; RAC1 PROTEIN; RECOMBINANT ALPHA2B INTERFERON; TREOSULFAN; UNCLASSIFIED DRUG; DOCK2 PROTEIN, HUMAN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAC1 PROTEIN, HUMAN;

ACTIN POLYMERIZATION; ALLELE; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AMYLASE BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; ARTIFICIAL VENTILATION; AUTOPSY; B LYMPHOCYTE; BRONCHIOLITIS; CANDIDIASIS; CAUSE OF DEATH; CELL DEATH; CELL MIGRATION; CELLULAR IMMUNITY; CEREBROSPINAL FLUID; CHICKENPOX; CHILD; CLINICAL ARTICLE; COAGULATION NECROSIS; CONSANGUINITY; CONTROLLED STUDY; DEGRANULATION; DIARRHEA; DISEASE ASSOCIATION; DOCK2 GENE; DRUG MEGADOSE; EARLY ONSET INVASIVE INFECTION; FEMALE; FEVER; FIBROBLAST; GENE; GENE MUTATION; GENETIC DISORDER; GENETICS; GRANULOMATOUS INFLAMMATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATOMEGALY; HLA MATCHING; HOSPITALIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; INFECTION; INHERITED DOCK2 DEFICIENCY; INTERSTITIAL PNEUMONIA; LEUKOCYTE; LIVER BIOPSY; LUNG BIOPSY; LUNG INFILTRATE; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; MALE; MENINGOENCEPHALITIS; MONOCYTE; MUMPS; MYELOABLATIVE CONDITIONING; NATURAL KILLER CELL; NECROSIS; NEUTROPHIL; OTITIS MEDIA; OUTCOME ASSESSMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCED INTENSITY CONDITIONING; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT INFECTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THROMBOCYTOPENIA; VIRUS INFECTION; VIRUS PNEUMONIA; VIRUS REPLICATION; CASE REPORT; DEFICIENCY; FATALITY; GENETIC DISEASES, INBORN; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGY; METABOLISM; MUTATION; PEDIGREE; RECESSIVE GENE;

B-LYMPHOCYTES; CHILD, PRESCHOOL; FATAL OUTCOME; FEMALE; GENES, RECESSIVE; GENETIC DISEASES, INBORN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFANT; KILLER CELLS, NATURAL; MALE; MUTATION; PEDIGREE; RAC1 GTP-BINDING PROTEIN; T-LYMPHOCYTES;

EID: 84931403287     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1413462     Document Type: Article

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