Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis

Gastroenterology

Volumn 141, Issue 2, 2011, Pages 633-641

  Muise, Aleixo M ^a,b   Walters, Thomas ^a   Xu, Wei ^c   Shentu, Grace ^b   Guo, Conghui ^b   Fattouh, Ramzi ^a,b   Lam, Grace Y ^a,b   Wolters, Victorien M ^a   Bennitz, Joshua ^b   Van Limbergen, Johan ^a   Renbaum, Paul ^d   Kasirer, Yair ^d   Ngan, Boyee ^b   Turner, Dan ^d   Denson, Lee A ^e   Sherman, Philip M ^a,b   Duerr, Richard H ^f,g   Cho, Judy ^h   Lees, Charlie W ⁱ   Satsangi, Jack ⁱ   Wilson, David C ⁱ   Paterson, Andrew D ^c   Griffiths, Anne M ^a   Glogauer, Michael ^c   Silverberg, Mark S ^c   Brumell, John H ^a,b   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f Institute for Cell Engineering   (United States)

^g UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^h YALE UNIVERSITY   (United States)

ⁱ UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

CD; Innate Immunity; Rac 1 Knockout; Ulcerative Colitis

Indexed keywords

DEXTRAN SULFATE; GUANOSINE TRIPHOSPHATE; RAC1 PROTEIN; RNA;

ANIMAL EXPERIMENT; ARTICLE; BLOOD CELL; COHORT ANALYSIS; CONTROLLED STUDY; ENTERITIS; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; MACROPHAGE; MAJOR CLINICAL STUDY; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

EID: 80051494421     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.04.057     Document Type: Article

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