G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis

Molecular Immunology

Volumn 54, Issue 2, 2013, Pages 193-198

  Giguère, Patrick M ^a   Billard, Matthew J ^a   Laroche, Geneviève ^a   Buckley, Brian K ^a   Timoshchenko, Roman G ^a   McGinnis, Marcus W ^a   Esserman, Denise ^b   Foreman, Oded ^c   Liu, Peng ^a   Siderovski, David P ^d   Tarrant, Teresa K ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c JACKSON LABORATORY   (United States)

^d WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmune diseases; Cell signaling molecules; Collagen induced arthritis; Macrophages; Rheumatoid arthritis

Indexed keywords

BIOLOGICAL MARKER; G PROTEIN SIGNALING MODULATOR 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; BONE MARROW CELL; CELL SURVIVAL; CHEMOTAXIS; COLLAGEN ANTIBODY INDUCED ARTHRITIS; CONTROLLED STUDY; DISEASE MARKER; DNA POLYMORPHISM; FLOW CYTOMETRY; GENE LOCUS; GENETIC ASSOCIATION; HISTOPATHOLOGY; IMMUNOBLOTTING; IN VITRO STUDY; LEUKOCYTE FUNCTION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS;

MUS;

EID: 84871844178     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.12.001     Document Type: Article

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