-
1
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
Edwards, A. O. et al. Complement factor H polymorphism and age-related macular degeneration. Science 308, 421-424 (2005).
-
(2005)
Science
, vol.308
, pp. 421-424
-
-
Edwards, A.O.1
-
2
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines, J. L. et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 308, 419-421 (2005).
-
(2005)
Science
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
-
3
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein, R. J. et al. Complement factor H polymorphism in age-related macular degeneration. Science 308, 385-389 (2005).
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
-
4
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek, R. et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445, 881-885 (2007).
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
-
5
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling, T. M. et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316, 889-894 (2007).
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
-
6
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W. J. et al. Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci. USA 90, 1977-1981 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
-
7
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem, R. B., Yvert, G., Clinton, R. & Kruglyak, L. Genetic dissection of transcriptional regulation in budding yeast. Science 296, 752-755 (2002).
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
8
-
-
20144383240
-
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
-
Bystrykh, L. et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nature Genet. 37, 225-232 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 225-232
-
-
Bystrykh, L.1
-
9
-
-
20144386111
-
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
-
Chesler, E. J. et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nature Genet. 37, 233-242 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 233-242
-
-
Chesler, E.J.1
-
10
-
-
8844244726
-
Genetic inheritance of gene expression in human cell lines
-
Monks, S. A. et al. Genetic inheritance of gene expression in human cell lines. Am. J. Hum. Genet. 75, 1094-1105 (2004).
-
(2004)
Am. J. Hum. Genet
, vol.75
, pp. 1094-1105
-
-
Monks, S.A.1
-
11
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt, E. E. et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nature Genet. 37, 710-717 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 710-717
-
-
Schadt, E.E.1
-
12
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt, E. E. et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 422, 297-302 (2003).
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
-
13
-
-
0033518234
-
From molecular to modular cell biology
-
Hartwell, L. H., Hopfield, J. J., Leibler, S. & Murray, A. W. From molecular to modular cell biology. Nature 402, C47-C52 (1999).
-
(1999)
Nature
, vol.402
-
-
Hartwell, L.H.1
Hopfield, J.J.2
Leibler, S.3
Murray, A.W.4
-
14
-
-
27844446240
-
Embracing complexity, inching closer to reality
-
pe40 2005
-
Schadt, E. E., Sachs, A. & Friend, S. Embracing complexity, inching closer to reality. Sci. STKE 2005, pe40 (2005).
-
(2005)
Sci. STKE
-
-
Schadt, E.E.1
Sachs, A.2
Friend, S.3
-
15
-
-
0023391441
-
Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility
-
Paigen, B., Albee, D., Holmes, P. A. & Mitchell, D. Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility. Biochem. Genet. 25, 501-511 (1987).
-
(1987)
Biochem. Genet
, vol.25
, pp. 501-511
-
-
Paigen, B.1
Albee, D.2
Holmes, P.A.3
Mitchell, D.4
-
16
-
-
33746681910
-
Tissue-specific expression and regulation of sexually dimorphic genes in mice
-
Yang, X. et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res. 16, 995-1004 (2006).
-
(2006)
Genome Res
, vol.16
, pp. 995-1004
-
-
Yang, X.1
-
17
-
-
33645770040
-
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity
-
Wang, S. et al. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. PLoS Genet. 2, e15 (2006).
-
(2006)
PLoS Genet
, vol.2
-
-
Wang, S.1
-
18
-
-
0342855957
-
Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice
-
Paigen, B. et al. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Proc. Natl Acad. Sci. USA 84, 3763-3767 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 3763-3767
-
-
Paigen, B.1
-
19
-
-
0035123369
-
Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance
-
Castellani, L. W., Goto, A. M. & Lusis, A. J. Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance. Diabetes 50, 643-651 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 643-651
-
-
Castellani, L.W.1
Goto, A.M.2
Lusis, A.J.3
-
20
-
-
4644219642
-
Haplotype analysis in multiple crosses to identify a QTL gene
-
Wang, X., Korstanje, R., Higgins, D. & Paigen, B. Haplotype analysis in multiple crosses to identify a QTL gene. Genome Res. 14, 1767-1772 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 1767-1772
-
-
Wang, X.1
Korstanje, R.2
Higgins, D.3
Paigen, B.4
-
21
-
-
20144386616
-
Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
-
Wang, X. et al. Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nature Genet. 37, 365-372 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 365-372
-
-
Wang, X.1
-
22
-
-
0027279942
-
Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II
-
Warden, C. H., Hedrick, C. C., Qiao, J. H., Castellani, L. W. & Lusis, A. J. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II. Science 261, 469-472 (1993).
-
(1993)
Science
, vol.261
, pp. 469-472
-
-
Warden, C.H.1
Hedrick, C.C.2
Qiao, J.H.3
Castellani, L.W.4
Lusis, A.J.5
-
23
-
-
1842509761
-
Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: Confirmation of a chromosome 6 locus in a congenic strain
-
Welch, C. L. et al. Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain. Physiol. Genomics 17, 48-59 (2004).
-
(2004)
Physiol. Genomics
, vol.17
, pp. 48-59
-
-
Welch, C.L.1
-
24
-
-
0025007039
-
A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition
-
Doolittle, M. H., LeBoeuf, R. C., Warden, C. H., Bee, L. M. & Lusis, A. J. A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition. J. Biol. Chem. 265, 16380-16388 (1990).
-
(1990)
J. Biol. Chem
, vol.265
, pp. 16380-16388
-
-
Doolittle, M.H.1
LeBoeuf, R.C.2
Warden, C.H.3
Bee, L.M.4
Lusis, A.J.5
-
25
-
-
12144287541
-
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
-
Pajukanta, P. et al. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nature Genet. 36, 371-376 (2004).
-
(2004)
Nature Genet
, vol.36
, pp. 371-376
-
-
Pajukanta, P.1
-
26
-
-
0036851155
-
F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: Role in inflammatory thrombosis
-
Babinska, A. et al. F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis. Thromb. Haemost. 88, 843-850 (2002).
-
(2002)
Thromb. Haemost
, vol.88
, pp. 843-850
-
-
Babinska, A.1
-
27
-
-
24144435303
-
Familial combined hyperlipidemia in Mexicans: Association with upstream transcription factor 1 and linkage on chromosome 16q24.1
-
Huertas-Vazquez, A. et al. Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arterioscler. Thromb. Vasc. Biol. 25, 1985-1991 (2005).
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.25
, pp. 1985-1991
-
-
Huertas-Vazquez, A.1
-
28
-
-
33644820005
-
Chlamydia pneumoniae infections augment atherosclerotic lesion formation: A role for serum amyloid P
-
Ezzahiri, R. et al. Chlamydia pneumoniae infections augment atherosclerotic lesion formation: a role for serum amyloid P. APMIS 114, 117-126 (2006).
-
(2006)
APMIS
, vol.114
, pp. 117-126
-
-
Ezzahiri, R.1
-
29
-
-
33644867724
-
Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: Loss of RGS5 distinguishes the cap
-
Adams, L. D., Geary, R. L., Li, J., Rossini, A. & Schwartz, S. M. Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap. Arterioscler. Thromb. Vasc. Biol. 26, 319-325 (2006).
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 319-325
-
-
Adams, L.D.1
Geary, R.L.2
Li, J.3
Rossini, A.4
Schwartz, S.M.5
-
30
-
-
33846593313
-
Multiple genes for essential-hypertension susceptibility on chromosome 1q
-
Chang, Y. P. et al. Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am. J. Hum. Genet. 80, 253-264 (2007).
-
(2007)
Am. J. Hum. Genet
, vol.80
, pp. 253-264
-
-
Chang, Y.P.1
-
31
-
-
27644549928
-
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits
-
Mehrabian, M. et al. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nature Genet. 37, 1224-1233 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 1224-1233
-
-
Mehrabian, M.1
-
32
-
-
0019784850
-
-
Austyn, J. M. & Gordon, S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11, 805-815 (1981).
-
Austyn, J. M. & Gordon, S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11, 805-815 (1981).
-
-
-
-
33
-
-
0029966853
-
Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein
-
Ramprasad, M. P., Terpstra, V., Kondratenko, N., Quehenberger, O. & Steinberg, D. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl Acad. Sci. USA 93, 14833-14838 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 14833-14838
-
-
Ramprasad, M.P.1
Terpstra, V.2
Kondratenko, N.3
Quehenberger, O.4
Steinberg, D.5
-
34
-
-
0025166114
-
-
Wright, S. D., Ramos, R. A., Tobias, P. S., Ulevitch, R. J. & Mathison, J. C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249, 1431-1433 (1990).
-
Wright, S. D., Ramos, R. A., Tobias, P. S., Ulevitch, R. J. & Mathison, J. C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249, 1431-1433 (1990).
-
-
-
-
35
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota, N. et al. PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell 4, 597-609 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
-
36
-
-
33748745775
-
A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases
-
Hu, Y., Liu, W., Huang, R. & Zhang, X. A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases. J. Lipid Res. 47, 1908-1914 (2006).
-
(2006)
J. Lipid Res
, vol.47
, pp. 1908-1914
-
-
Hu, Y.1
Liu, W.2
Huang, R.3
Zhang, X.4
-
37
-
-
0036775676
-
Lipoprotein lipase: The regulation of tissue specific expression and its role in lipid and energy metabolism
-
Preiss-Landl, K., Zimmermann, R., Hammerle, G. & Zechner, R. Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr. Opin. Lipidol. 13, 471-481 (2002).
-
(2002)
Curr. Opin. Lipidol
, vol.13
, pp. 471-481
-
-
Preiss-Landl, K.1
Zimmermann, R.2
Hammerle, G.3
Zechner, R.4
-
38
-
-
0342475730
-
Tissue-specific lipoprotein lipase: Relationships to body composition and body fat distribution in normal weight humans
-
Yost, T. J., Jensen, D. R. & Eckel, R. H. Tissue-specific lipoprotein lipase: relationships to body composition and body fat distribution in normal weight humans. Obes. Res. 1, 1-4 (1993).
-
(1993)
Obes. Res
, vol.1
, pp. 1-4
-
-
Yost, T.J.1
Jensen, D.R.2
Eckel, R.H.3
-
39
-
-
31044451266
-
Expression and purification of the mitochondrial serine protease LACTB as an N-terminal GST fusion protein in Escherichia coli
-
Liobikas, J. et al. Expression and purification of the mitochondrial serine protease LACTB as an N-terminal GST fusion protein in Escherichia coli. Protein Expr. Purif. 45, 335-342 (2006).
-
(2006)
Protein Expr. Purif
, vol.45
, pp. 335-342
-
-
Liobikas, J.1
-
40
-
-
0034762371
-
Identification, genomic organization, and mRNA expression of LACTB, encoding a serine β-lactamase-like protein with an amino-terminal transmembrane domain
-
Smith, T. S. et al. Identification, genomic organization, and mRNA expression of LACTB, encoding a serine β-lactamase-like protein with an amino-terminal transmembrane domain. Genomics 78, 12-14 (2001).
-
(2001)
Genomics
, vol.78
, pp. 12-14
-
-
Smith, T.S.1
-
41
-
-
0031555368
-
Life in the balance: Cell walls and antibiotic resistance
-
Jacobs, C. Life in the balance: cell walls and antibiotic resistance. Science 278, 1731-1732 (1997).
-
(1997)
Science
, vol.278
, pp. 1731-1732
-
-
Jacobs, C.1
-
42
-
-
4444376922
-
Expanded coverage of the human heart mitochondrial proteome using multidimensional liquid chromatography coupled with tandem mass spectrometry
-
Gaucher, S. P. et al. Expanded coverage of the human heart mitochondrial proteome using multidimensional liquid chromatography coupled with tandem mass spectrometry. J. Proteome Res. 3, 495-505 (2004).
-
(2004)
J. Proteome Res
, vol.3
, pp. 495-505
-
-
Gaucher, S.P.1
-
43
-
-
10744224439
-
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
-
Mootha, V. K. et al. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115, 629-640 (2003).
-
(2003)
Cell
, vol.115
, pp. 629-640
-
-
Mootha, V.K.1
-
44
-
-
0037336905
-
Characterization of the human heart mitochondrial proteome
-
Taylor, S. W. et al. Characterization of the human heart mitochondrial proteome. Nature Biotechnol. 21, 281-286 (2003).
-
(2003)
Nature Biotechnol
, vol.21
, pp. 281-286
-
-
Taylor, S.W.1
-
45
-
-
2542419065
-
Visceral obesity without insulin resistance in late-onset obesity rats
-
Bains, R. K. et al. Visceral obesity without insulin resistance in late-onset obesity rats. Endocrinology 145, 2666-2679 (2004).
-
(2004)
Endocrinology
, vol.145
, pp. 2666-2679
-
-
Bains, R.K.1
-
46
-
-
33845569346
-
Reverse engineering gene networks to identify key drivers of complex disease phenotypes
-
Schadt, E. E. & Lum, P. Y. Reverse engineering gene networks to identify key drivers of complex disease phenotypes. J. Lipid Res. 47, 2601-2013 (2006).
-
(2006)
J. Lipid Res
, vol.47
, pp. 2601-2013
-
-
Schadt, E.E.1
Lum, P.Y.2
-
47
-
-
33646841491
-
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes
-
Lum, P. Y. et al. Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J. Neurochem. 97 (suppl. 1), 50-62 (2006).
-
(2006)
J. Neurochem
, vol.97
, Issue.SUPPL. 1
, pp. 50-62
-
-
Lum, P.Y.1
-
48
-
-
0037199968
-
Hierarchical organization of modularity in metabolic networks
-
Ravasz, E., Somera, A. L., Mongru, D. A., Oltvai, Z. N. & Barabasi, A. L. Hierarchical organization of modularity in metabolic networks. Science 297, 1551-1555 (2002).
-
(2002)
Science
, vol.297
, pp. 1551-1555
-
-
Ravasz, E.1
Somera, A.L.2
Mongru, D.A.3
Oltvai, Z.N.4
Barabasi, A.L.5
-
49
-
-
33646942472
-
-
Haley, C. S. & Knott, S. A. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69, 315-324 (1992).
-
Haley, C. S. & Knott, S. A. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69, 315-324 (1992).
-
-
-
-
50
-
-
0029022716
-
Multiple trait analysis of genetic mapping for quantitative trait loci
-
Jiang, C. & Zeng, Z. B. Multiple trait analysis of genetic mapping for quantitative trait loci. Genetics 140, 1111-1127 (1995).
-
(1995)
Genetics
, vol.140
, pp. 1111-1127
-
-
Jiang, C.1
Zeng, Z.B.2
|