-
1
-
-
0032551901
-
Staphylococcus aureus infections
-
Lowy, F. D. Staphylococcus aureus infections. N. Engl. J. Med. 339, 520-532 (1998).
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 520-532
-
-
Lowy, F.D.1
-
2
-
-
79952033104
-
Clinical management of staphylococcus aureus bacteraemia
-
Thwaites, G. E. et al. Clinical management of Staphylococcus aureus bacteraemia. Lancet Infect. Dis. 11, 208-222 (2011).
-
(2011)
Lancet Infect. Dis.
, vol.11
, pp. 208-222
-
-
Thwaites, G.E.1
-
3
-
-
77951620048
-
Community associated meticillin resistant staphylococcus aureus
-
Deleo, F. R., Otto, M., Kreiswirth, B. N. & Chambers, H. F. Community associated meticillin resistant Staphylococcus aureus. Lancet 375, 1557-1568 (2010).
-
(2010)
Lancet
, vol.375
, pp. 1557-1568
-
-
Deleo, F.R.1
Otto, M.2
Kreiswirth, B.N.3
Chambers, H.F.4
-
4
-
-
84939481931
-
Staphylococcal manipulation of host immune responses
-
Thammavongsa, V., Kim, H. K., Missiakas, D. & Schneewind, O. Staphylococcal manipulation of host immune responses. Nat. Rev. Microbiol. 13, 529-543 (2015).
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 529-543
-
-
Thammavongsa, V.1
Kim, H.K.2
Missiakas, D.3
Schneewind, O.4
-
5
-
-
80053236138
-
Molecular mechanisms of staphylococcus aureus iron acquisition
-
Hammer, N. D. & Skaar, E. P. Molecular mechanisms of Staphylococcus aureus iron acquisition. Annu. Rev. Microbiol. 65, 129-147 (2011).
-
(2011)
Annu. Rev. Microbiol.
, vol.65
, pp. 129-147
-
-
Hammer, N.D.1
Skaar, E.P.2
-
6
-
-
4644310922
-
Iron source preference of staphylococcus aureus infections
-
Skaar, E. P., Humayun, M., Bae, T., DeBord, K. L. & Schneewind, O. Iron source preference of Staphylococcus aureus infections. Science 305, 1626-1628 (2004).
-
(2004)
Science
, vol.305
, pp. 1626-1628
-
-
Skaar, E.P.1
Humayun, M.2
Bae, T.3
DeBord, K.L.4
Schneewind, O.5
-
7
-
-
84901058157
-
The bicomponent pore-forming leucocidins of staphylococcus aureus
-
Alonzo, F. III & Torres, V. J. The bicomponent pore-forming leucocidins of Staphylococcus aureus. Microbiol. Mol. Biol. Rev. 78, 199-230 (2014).
-
(2014)
Microbiol. Mol. Biol. Rev.
, vol.78
, pp. 199-230
-
-
Alonzo, F.1
Torres, V.J.2
-
8
-
-
84884279163
-
Phenol soluble modulins and staphylococcal infection
-
Peschel, A. & Otto, M. Phenol soluble modulins and staphylococcal infection. Nat. Rev. Microbiol. 11, 667-673 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 667-673
-
-
Peschel, A.1
Otto, M.2
-
9
-
-
84884513903
-
Neutrophils versus staphylococcus aureus: A biological tug of war
-
Spaan, A. N., Surewaard, B. G., Nijland, R. & van Strijp, J. A. Neutrophils versus Staphylococcus aureus: a biological tug of war. Annu. Rev. Microbiol. 67, 629-650 (2013).
-
(2013)
Annu. Rev. Microbiol.
, vol.67
, pp. 629-650
-
-
Spaan, A.N.1
Surewaard, B.G.2
Nijland, R.3
Van Strijp, J.A.4
-
10
-
-
84871814560
-
CCR5 is a receptor for staphylococcus aureus leukotoxin ED
-
Alonzo, F. III et al. CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature 493, 51-55 (2013).
-
(2013)
Nature
, vol.493
, pp. 51-55
-
-
Alonzo, F.1
-
11
-
-
84877757139
-
Staphylococcus aureus hemolysins, bi component leukocidins, and cytolytic peptides: A redundant arsenal of membrane-damaging virulence factors?
-
Vandenesch, F., Lina, G. & Henry, T. Staphylococcus aureus hemolysins, bi component leukocidins, and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors? Front. Cell. Infect. Microbiol. 2, 12 (2012).
-
(2012)
Front. Cell. Infect. Microbiol.
, vol.2
, pp. 12
-
-
Vandenesch, F.1
Lina, G.2
Henry, T.3
-
12
-
-
50249218564
-
Staphylococcal toxin
-
Panton, P. N. & Valentine, F. C. O. Staphylococcal toxin. Lancet 219, 506-508 (1932).
-
(1932)
Lancet
, vol.219
, pp. 506-508
-
-
Panton, P.N.1
Valentine, F.C.O.2
-
13
-
-
84879131303
-
Staphylococcus aureus α-toxin: Nearly a century of intrigue
-
Berube, B. J. & Bubeck Wardenburg, J. Staphylococcus aureus α-toxin: nearly a century of intrigue. Toxins (Basel) 5, 1140-1166 (2013).
-
(2013)
Toxins (Basel)
, vol.5
, pp. 1140-1166
-
-
Berube, B.J.1
Bubeck Wardenburg, J.2
-
14
-
-
84955193035
-
Pore-forming toxins: Ancient, but never really out of fashion
-
Peraro, M. D. & van der Goot, F. G. Pore-forming toxins: ancient, but never really out of fashion. Nat. Rev. Microbiol. 14, 77-92 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 77-92
-
-
Peraro, M.D.1
Van Der-Goot, F.G.2
-
15
-
-
0028801187
-
Characterisation of a synergohymenotropic toxin produced by staphylococcus intermedius
-
Prevost, G., Bouakham, T., Piemont, Y. & Monteil, H. Characterisation of a synergohymenotropic toxin produced by Staphylococcus intermedius. FEBS Lett. 376, 135-140 (1995).
-
(1995)
FEBS Lett.
, vol.376
, pp. 135-140
-
-
Prevost, G.1
Bouakham, T.2
Piemont, Y.3
Monteil, H.4
-
16
-
-
85010041795
-
Identification of LukPQ, a novel, equid-adapted leukocidin of staphylococcus aureus
-
Koop, G. et al. Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus. Sci. Rep. 7, 40660 (2017).
-
(2017)
Sci. Rep.
, vol.7
, pp. 40660
-
-
Koop, G.1
-
17
-
-
77649223154
-
Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils
-
Loffler, B. et al. Staphylococcus aureus Panton-Valentine leukocidin is a very potent cytotoxic factor for human neutrophils. PLoS Pathog. 6, e1000715 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000715
-
-
Loffler, B.1
-
18
-
-
80054794259
-
Crystal structure of the octameric pore of staphylococcal γ-hemolysin reveals the β-barrel pore formation mechanism by two components
-
Yamashita, K. et al. Crystal structure of the octameric pore of staphylococcal γ-hemolysin reveals the β-barrel pore formation mechanism by two components. Proc. Natl Acad. Sci. USA 108, 17314-17319 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 17314-17319
-
-
Yamashita, K.1
-
19
-
-
84894266542
-
Identification of a crucial residue required for staphylococcus aureus LukAB cytotoxicity and receptor recognition
-
DuMont, A. L. et al. Identification of a crucial residue required for Staphylococcus aureus LukAB cytotoxicity and receptor recognition. Infect. Immun. 82, 1268-1276 (2014).
-
(2014)
Infect. Immun.
, vol.82
, pp. 1268-1276
-
-
DuMont, A.L.1
-
20
-
-
84923247291
-
Molecular basis of transmembrane β-barrel formation of staphylococcal pore-forming toxins
-
Yamashita, D. et al. Molecular basis of transmembrane β-barrel formation of staphylococcal pore-forming toxins. Nat. Commun. 5, 4897 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 4897
-
-
Yamashita, D.1
-
21
-
-
84920531939
-
Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the staphylococcus aureus bi component toxin LukGH
-
Badarau, A. et al. Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi component toxin LukGH. J. Biol. Chem. 290, 142-156 (2015).
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 142-156
-
-
Badarau, A.1
-
22
-
-
84984871095
-
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of staphylococcus aureus for the generation of neutralizing antibodies
-
Badarau, A. et al. Context matters: the importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies. mAbs 8, 1347-1360 (2016).
-
(2016)
MAbs
, vol.8
, pp. 1347-1360
-
-
Badarau, A.1
-
23
-
-
0036716731
-
Stochastic assembly of two-component staphylococcal γ-hemolysin into heteroheptameric transmembrane pores with alternate subunit arrangements in ratios of 3:4 and 4:3
-
Sugawara-Tomita, N., Tomita, T. & Kamio, Y. Stochastic assembly of two-component staphylococcal γ-hemolysin into heteroheptameric transmembrane pores with alternate subunit arrangements in ratios of 3:4 and 4:3. J. Bacteriol. 184, 4747-4756 (2002).
-
(2002)
J. Bacteriol.
, vol.184
, pp. 4747-4756
-
-
Sugawara-Tomita, N.1
Tomita, T.2
Kamio, Y.3
-
24
-
-
34547510914
-
Membrane protein stoichiometry determined from the step wise photobleaching of dye-labelled subunits
-
Das, S. K., Darshi, M., Cheley, S., Wallace, M. I. & Bayley, H. Membrane protein stoichiometry determined from the step wise photobleaching of dye-labelled subunits. Chembiochem 8, 994-999 (2007).
-
(2007)
Chembiochem
, vol.8
, pp. 994-999
-
-
Das, S.K.1
Darshi, M.2
Cheley, S.3
Wallace, M.I.4
Bayley, H.5
-
25
-
-
0028132877
-
Interaction of the two components of leukocidin from staphylococcus aureus with human polymorphonuclear leukocyte membranes: Sequential binding and subsequent activation
-
Colin, D. A., Mazurier, I., Sire, S. & Finck-Barbancon, V. Interaction of the two components of leukocidin from Staphylococcus aureus with human polymorphonuclear leukocyte membranes: sequential binding and subsequent activation. Infect. Immun. 62, 3184-3188 (1994).
-
(1994)
Infect. Immun.
, vol.62
, pp. 3184-3188
-
-
Colin, D.A.1
Mazurier, I.2
Sire, S.3
Finck-Barbancon, V.4
-
26
-
-
0030987870
-
A predicted β-sheet from class S components of staphylococcal γ-hemolysin is essential for the secondary interaction of the class F component
-
Meunier, O. et al. A predicted β-sheet from class S components of staphylococcal γ-hemolysin is essential for the secondary interaction of the class F component. Biochim. Biophys. Acta 1326, 275-286 (1997).
-
(1997)
Biochim. Biophys. Acta
, vol.1326
, pp. 275-286
-
-
Meunier, O.1
-
27
-
-
0035080948
-
Flow cytometric determination of panton-valentine leucocidin S component binding
-
Gauduchon, V., Werner, S., Prevost, G., Monteil, H. & Colin, D. A. Flow cytometric determination of Panton-Valentine leucocidin S component binding. Infect. Immun. 69, 2390-2395 (2001).
-
(2001)
Infect. Immun.
, vol.69
, pp. 2390-2395
-
-
Gauduchon, V.1
Werner, S.2
Prevost, G.3
Monteil, H.4
Colin, D.A.5
-
28
-
-
58449091019
-
Analysis of the specificity of panton-valentine leucocidin and γ-hemolysin F component binding
-
Meyer, F., Girardot, R., Piemont, Y., Prevost, G. & Colin, D. A. Analysis of the specificity of Panton-Valentine leucocidin and γ-hemolysin F component binding. Infect. Immun. 77, 266-273 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 266-273
-
-
Meyer, F.1
Girardot, R.2
Piemont, Y.3
Prevost, G.4
Colin, D.A.5
-
29
-
-
0029319728
-
Essential binding of LukF of staphylococcal γ-hemolysin followed by the binding of HγII for the hemolysis of human erythrocytes
-
Ozawa, T., Kaneko, J. & Kamio, Y. Essential binding of LukF of staphylococcal γ-hemolysin followed by the binding of HγII for the hemolysis of human erythrocytes. Biosci. Biotechnol. Biochem. 59, 1181-1183 (1995).
-
(1995)
Biosci. Biotechnol. Biochem.
, vol.59
, pp. 1181-1183
-
-
Ozawa, T.1
Kaneko, J.2
Kamio, Y.3
-
30
-
-
0031148369
-
Sequential binding of staphylococcal γ-hemolysin to human erythrocytes and complex formation of the hemolysin on the cell surface
-
Kaneko, J., Ozawa, T., Tomita, T. & Kamio, Y. Sequential binding of staphylococcal γ-hemolysin to human erythrocytes and complex formation of the hemolysin on the cell surface. Biosci. Biotechnol. Biochem. 61, 846-851 (1997).
-
(1997)
Biosci. Biotechnol. Biochem.
, vol.61
, pp. 846-851
-
-
Kaneko, J.1
Ozawa, T.2
Tomita, T.3
Kamio, Y.4
-
31
-
-
0032508971
-
The interaction of staphylococcus aureus bi component γ-hemolysins and leucocidins with cells and lipid membranes
-
Ferreras, M. et al. The interaction of Staphylococcus aureus bi component γ-hemolysins and leucocidins with cells and lipid membranes. Biochim. Biophys. Acta 1414, 108-126 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1414
, pp. 108-126
-
-
Ferreras, M.1
-
32
-
-
0037242676
-
Purification, cloning and characterization of variant LukE-LukD with strong leukocidal activity of staphylococcal bi component leukotoxin family
-
Morinaga, N., Kaihou, Y. & Noda, M. Purification, cloning and characterization of variant LukE-LukD with strong leukocidal activity of staphylococcal bi component leukotoxin family. Microbiol. Immunol. 47, 81-90 (2003).
-
(2003)
Microbiol. Immunol.
, vol.47
, pp. 81-90
-
-
Morinaga, N.1
Kaihou, Y.2
Noda, M.3
-
33
-
-
84959470571
-
Exploiting dominant negative toxins to combat staphylococcus aureus pathogenesis
-
Reyes-Robles, T., Lubkin, A., Alonzo, F. III, Lacy, D. B. & Torres, V. J. Exploiting dominant negative toxins to combat Staphylococcus aureus pathogenesis. EMBO Rep. 17, 428-440 (2016).
-
(2016)
EMBO Rep.
, vol.17
, pp. 428-440
-
-
Reyes-Robles, T.1
Lubkin, A.2
Alonzo, F.3
Lacy, D.B.4
Torres, V.J.5
-
34
-
-
84877867535
-
The staphylococcal toxin panton-valentine leukocidin targets human C5a receptors
-
Spaan, A. N. et al. The staphylococcal toxin Panton-Valentine leukocidin targets human C5a receptors. Cell Host Microbe 13, 584-594 (2013).
-
(2013)
Cell Host Microbe
, vol.13
, pp. 584-594
-
-
Spaan, A.N.1
-
35
-
-
84886079502
-
Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection
-
Reyes-Robles, T. et al. Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection. Cell Host Microbe 14, 453-459 (2013).
-
(2013)
Cell Host Microbe
, vol.14
, pp. 453-459
-
-
Reyes-Robles, T.1
-
36
-
-
84925274771
-
The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors
-
Spaan, A. N. et al. The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors. Nat. Commun. 5, 5438 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5438
-
-
Spaan, A.N.1
-
37
-
-
84879518407
-
Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin mac 1
-
DuMont, A. L. et al. Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac 1. Proc. Natl Acad. Sci. USA 110, 10794-10799 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 10794-10799
-
-
DuMont, A.L.1
-
38
-
-
84941275915
-
Staphylococcus aureus targets the duffy antigen receptor for chemokines (DARC) to lyse erythrocytes
-
Spaan, A. N. et al. Staphylococcus aureus targets the Duffy antigen receptor for chemokines (DARC) to lyse erythrocytes. Cell Host Microbe 18, 363-370 (2015).
-
(2015)
Cell Host Microbe
, vol.18
, pp. 363-370
-
-
Spaan, A.N.1
-
39
-
-
84936966487
-
Bovine staphylococcus aureus secretes the leukocidin LukMF' to kill migrating neutrophils through CCR1
-
Vrieling, M. et al. Bovine Staphylococcus aureus secretes the leukocidin LukMF' to kill migrating neutrophils through CCR1. mBio 6, e00335 (2015).
-
(2015)
MBio
, vol.6
, pp. e00335
-
-
Vrieling, M.1
-
40
-
-
84873685831
-
Molecular signatures of G protein-coupled receptors
-
Venkatakrishnan, A. J. et al. Molecular signatures of G protein-coupled receptors. Nature 494, 185-194 (2013).
-
(2013)
Nature
, vol.494
, pp. 185-194
-
-
Venkatakrishnan, A.J.1
-
41
-
-
0029001881
-
Disruption of a GATA motif in the duffy gene promoter abolishes erythroid gene expression in duffy-negative individuals
-
Tournamille, C., Colin, Y., Cartron, J. P. & Le Van Kim, C. Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat. Genet. 10, 224-228 (1995).
-
(1995)
Nat. Genet.
, vol.10
, pp. 224-228
-
-
Tournamille, C.1
Colin, Y.2
Cartron, J.P.3
Le Van-Kim, C.4
-
43
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes, R. O. Integrins: bidirectional, allosteric signaling machines. Cell 110, 673-687 (2002).
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
44
-
-
84875804760
-
The effects of staphylococcus aureus leukotoxins on the host: Cell lysis and beyond
-
Yoong, P. & Torres, V. J. The effects of Staphylococcus aureus leukotoxins on the host: cell lysis and beyond. Curr. Opin. Microbiol. 16, 63-69 (2013).
-
(2013)
Curr. Opin. Microbiol.
, vol.16
, pp. 63-69
-
-
Yoong, P.1
Torres, V.J.2
-
45
-
-
85007564155
-
Staphylococcus aureus leukocidin LukED and HIV 1 gp120 target different sequence determinants on CCR5
-
16
-
Tam, K. et al. Staphylococcus aureus leukocidin LukED and HIV 1 gp120 target different sequence determinants on CCR5. mBio 7, e02024 16 (2016).
-
(2016)
MBio
, vol.7
, pp. e02024
-
-
Tam, K.1
-
46
-
-
84898639720
-
Residues essential for panton-valentine leukocidin S component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
-
Laventie, B. J. et al. Residues essential for Panton-Valentine leukocidin S component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface. PLoS ONE 9, e92094 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e92094
-
-
Laventie, B.J.1
-
47
-
-
84937693948
-
Differential interaction of the staphylococcal toxins panton-valentine leukocidin and γ-hemolysin CB with human C5a receptors
-
Spaan, A. N. et al. Differential interaction of the staphylococcal toxins Panton-Valentine leukocidin and γ-hemolysin CB with human C5a receptors. J. Immunol. 195, 1034-1043 (2015).
-
(2015)
J. Immunol.
, vol.195
, pp. 1034-1043
-
-
Spaan, A.N.1
-
48
-
-
85041292752
-
Staphylococcal immune evasion proteins: Structure, function, and host adaptation
-
Koymans, K. J., Vrieling, M., Gorham, R. D. Jr & van Strijp, J. A. Staphylococcal immune evasion proteins: structure, function, and host adaptation. Curr. Top. Microbiol. Immunol. http://dx.doi.org/10.1007/82-2015-5017 (2016).
-
(2016)
Curr. Top. Microbiol. Immunol.
-
-
Koymans, K.J.1
Vrieling, M.2
Gorham, R.D.3
Van Strijp, J.A.4
-
49
-
-
0028956547
-
Epidemiological data on staphylococcus aureus strains producing synergohymenotropic toxins
-
Prevost, G. et al. Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins. J. Med. Microbiol. 42, 237-245 (1995).
-
(1995)
J. Med. Microbiol.
, vol.42
, pp. 237-245
-
-
Prevost, G.1
-
50
-
-
3042828296
-
Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of staphylococcus aureus
-
von Eiff, C., Friedrich, A. W., Peters, G. & Becker, K. Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of Staphylococcus aureus. Diagn. Microbiol. Infect. Dis. 49, 157-162 (2004).
-
(2004)
Diagn. Microbiol. Infect. Dis.
, vol.49
, pp. 157-162
-
-
Von Eiff, C.1
Friedrich, A.W.2
Peters, G.3
Becker, K.4
-
51
-
-
0032541129
-
Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage φpVL carrying panton-valentine leukocidin genes
-
Kaneko, J., Kimura, T., Narita, S., Tomita, T. & Kamio, Y. Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage φPVL carrying Panton-Valentine leukocidin genes. Gene 215, 57-67 (1998).
-
(1998)
Gene
, vol.215
, pp. 57-67
-
-
Kaneko, J.1
Kimura, T.2
Narita, S.3
Tomita, T.4
Kamio, Y.5
-
52
-
-
0344738732
-
Comparison of community-and health care associated methicillin resistant staphylococcus aureus infection
-
Naimi, T. S. et al. Comparison of community-and health care associated methicillin resistant Staphylococcus aureus infection. JAMA 290, 2976-2984 (2003).
-
(2003)
JAMA
, vol.290
, pp. 2976-2984
-
-
Naimi, T.S.1
-
53
-
-
60849135405
-
Complete genome sequence of macrococcus caseolyticus strain JCSCS5402, reflecting the ancestral genome of the human-pathogenic staphylococci
-
Baba, T. et al. Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, reflecting the ancestral genome of the human-pathogenic staphylococci. J. Bacteriol. 191, 1180-1190 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 1180-1190
-
-
Baba, T.1
-
54
-
-
0027459158
-
The γ-hemolysin locus of staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin
-
Cooney, J., Kienle, Z., Foster, T. J. & O'Toole, P. W. The γ-hemolysin locus of Staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin. Infect. Immun. 61, 768-771 (1993).
-
(1993)
Infect. Immun.
, vol.61
, pp. 768-771
-
-
Cooney, J.1
Kienle, Z.2
Foster, T.J.3
O'Toole, P.W.4
-
55
-
-
58549096736
-
Quorum sensing in staphylococci
-
Novick, R. P. & Geisinger, E. Quorum sensing in staphylococci. Annu. Rev. Genet. 42, 541-564 (2008).
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 541-564
-
-
Novick, R.P.1
Geisinger, E.2
-
56
-
-
0035212002
-
Transcription profiling-based identification of staphylococcus aureus genes regulated by the agr and/or sarA loci
-
Dunman, P. M. et al. Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J. Bacteriol. 183, 7341-7353 (2001).
-
(2001)
J. Bacteriol.
, vol.183
, pp. 7341-7353
-
-
Dunman, P.M.1
-
57
-
-
84925884174
-
Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element
-
Benson, M. A. et al. Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element. Mol. Microbiol. 93, 664-681 (2014).
-
(2014)
Mol. Microbiol.
, vol.93
, pp. 664-681
-
-
Benson, M.A.1
-
58
-
-
84900480692
-
Differential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil derived stimuli
-
Flack, C. E. et al. Differential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil derived stimuli. Proc. Natl Acad. Sci. USA 111, E2037-E2045 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E2037-E2045
-
-
Flack, C.E.1
-
59
-
-
84893693729
-
The role of innate immunity in promoting SaeR/S mediated virulence in staphylococcus aureus
-
Zurek, O. W. et al. The role of innate immunity in promoting SaeR/S mediated virulence in Staphylococcus aureus. J. Innate Immun. 6, 21-30 (2014).
-
(2014)
J. Innate Immun.
, vol.6
, pp. 21-30
-
-
Zurek, O.W.1
-
60
-
-
24744461675
-
Insights into mechanisms used by staphylococcus aureus to avoid destruction by human neutrophils
-
Voyich, J. M. et al. Insights into mechanisms used by Staphylococcus aureus to avoid destruction by human neutrophils. J. Immunol. 175, 3907-3919 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 3907-3919
-
-
Voyich, J.M.1
-
61
-
-
67650679855
-
The SaeR/S gene regulatory system is essential for innate immune evasion by staphylococcus aureus
-
Voyich, J. M. et al. The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus. J. Infect. Dis. 199, 1698-1706 (2009).
-
(2009)
J. Infect. Dis.
, vol.199
, pp. 1698-1706
-
-
Voyich, J.M.1
-
62
-
-
79954531233
-
Global changes in staphylococcus aureus gene expression in human blood
-
Malachowa, N. et al. Global changes in Staphylococcus aureus gene expression in human blood. PLoS ONE 6, e18617 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e18617
-
-
Malachowa, N.1
-
63
-
-
84877835195
-
Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils
-
DuMont, A. L. et al. Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils. Infect. Immun. 81, 1830-1841 (2013).
-
(2013)
Infect. Immun.
, vol.81
, pp. 1830-1841
-
-
DuMont, A.L.1
-
64
-
-
84979021167
-
Staphylococcus aureus coordinates leukocidin expression and pathogenesis by sensing metabolic fluxes via RpiRc
-
16
-
Balasubramanian, D. et al. Staphylococcus aureus coordinates leukocidin expression and pathogenesis by sensing metabolic fluxes via RpiRc. mBio 7, e00818 16 (2016).
-
(2016)
MBio
, vol.7
, pp. e00818
-
-
Balasubramanian, D.1
-
65
-
-
78751680161
-
Characterization of a new cytotoxin that contributes to staphylococcus aureus pathogenesis
-
Dumont, A. L. et al. Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis. Mol. Microbiol. 79, 814-825 (2011).
-
(2011)
Mol. Microbiol.
, vol.79
, pp. 814-825
-
-
Dumont, A.L.1
-
66
-
-
77955399259
-
Identification of a novel staphylococcus aureus two-component leukotoxin using cell surface proteomics
-
Ventura, C. L. et al. Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics. PLoS ONE 5, e11634 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e11634
-
-
Ventura, C.L.1
-
67
-
-
77950472817
-
Rapid detection of staphylococcus aureus panton-valentine leukocidin in clinical specimens by enzyme linked immunosorbent assay and immunochromatographic tests
-
Badiou, C. et al. Rapid detection of Staphylococcus aureus Panton-Valentine leukocidin in clinical specimens by enzyme linked immunosorbent assay and immunochromatographic tests. J. Clin. Microbiol. 48, 1384-1390 (2010).
-
(2010)
J. Clin. Microbiol.
, vol.48
, pp. 1384-1390
-
-
Badiou, C.1
-
68
-
-
84900320307
-
Analysis of the staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface
-
Attia, A. S. et al. Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface. Pathog. Dis. 69, 36-48 (2013).
-
(2013)
Pathog. Dis.
, vol.69
, pp. 36-48
-
-
Attia, A.S.1
-
69
-
-
84899542544
-
Global gene expression of methicillin-resistant staphylococcus aureus USA300 during human and mouse infection
-
Date, S. V. et al. Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J. Infect. Dis. 209, 1542-1550 (2014).
-
(2014)
J. Infect. Dis.
, vol.209
, pp. 1542-1550
-
-
Date, S.V.1
-
70
-
-
84894270046
-
Children with invasive staphylococcus aureus disease exhibit a potently neutralizing antibody response to the cytotoxin LukAB
-
Thomsen, I. P. et al. Children with invasive Staphylococcus aureus disease exhibit a potently neutralizing antibody response to the cytotoxin LukAB. Infect. Immun. 82, 1234-1242 (2014).
-
(2014)
Infect. Immun.
, vol.82
, pp. 1234-1242
-
-
Thomsen, I.P.1
-
71
-
-
84947718172
-
Antibodies to S. Aureus LukS-PV attenuated subunit vaccine neutralize a broad spectrum of canonical and non-canonical bicomponent leukotoxin pairs
-
Adhikari, R. P. et al. Antibodies to S. aureus LukS-PV attenuated subunit vaccine neutralize a broad spectrum of canonical and non-canonical bicomponent leukotoxin pairs. PLoS ONE 10, e0137874 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0137874
-
-
Adhikari, R.P.1
-
72
-
-
77955783248
-
Role of a disintegrin and metalloprotease 10 in staphylococcus aureus α-hemolysin-mediated cellular injury
-
Wilke, G. A. & Bubeck Wardenburg, J. Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus α-hemolysin-mediated cellular injury. Proc. Natl Acad. Sci. USA 107, 13473-13478 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13473-13478
-
-
Wilke, G.A.1
Bubeck Wardenburg, J.2
-
73
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis, B., Wen, H. & Ting, J. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 29, 707-735 (2011).
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.1
Wen, H.2
Ting, J.3
-
74
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S. et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232 (2006).
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
-
75
-
-
84868314254
-
Staphylococcus aureus panton-valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome
-
Holzinger, D. et al. Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J. Leukoc. Biol. 92, 1069-1081 (2012).
-
(2012)
J. Leukoc. Biol.
, vol.92
, pp. 1069-1081
-
-
Holzinger, D.1
-
76
-
-
84936769144
-
Staphylococcus aureus leukocidin A/B (LukAB) kills human monocytes via host NLRP3 and ASC when extracellular, but not intracellular
-
Melehani, J. H., James, D. B., DuMont, A. L., Torres, V. J. & Duncan, J. A. Staphylococcus aureus leukocidin A/B (LukAB) kills human monocytes via host NLRP3 and ASC when extracellular, but not intracellular. PLoS Pathog. 11, e1004970 (2015).
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004970
-
-
Melehani, J.H.1
James, D.B.2
DuMont, A.L.3
Torres, V.J.4
Duncan, J.A.5
-
77
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in staphylococcus aureus-induced activation of the nlrp3 inflammasome
-
Munoz-Planillo, R., Franchi, L., Miller, L. S. & Nunez, G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Immunol. 183, 3942-3948 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
78
-
-
84879596906
-
+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38, 1142-1153 (2013).
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
-
79
-
-
84862526916
-
Cross-talk between staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner
-
Perret, M. et al. Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner. Cell. Microbiol. 14, 1019-1036 (2012).
-
(2012)
Cell. Microbiol.
, vol.14
, pp. 1019-1036
-
-
Perret, M.1
-
80
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi, J. et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526, 660-665 (2015).
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
-
81
-
-
84942856523
-
Caspase 11 cleaves gasdermin D for non canonical inflammasome signalling
-
Kayagaki, N. et al. Caspase 11 cleaves gasdermin D for non canonical inflammasome signalling. Nature 526, 666-671 (2015).
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
-
82
-
-
84978419608
-
Pore-forming activity and structural autoinhibition of the gasdermin family
-
Ding, J. et al. Pore-forming activity and structural autoinhibition of the gasdermin family. Nature 535, 111-116 (2016).
-
(2016)
Nature
, vol.535
, pp. 111-116
-
-
Ding, J.1
-
83
-
-
84978374487
-
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
-
Liu, X. et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature 535, 153-158 (2016).
-
(2016)
Nature
, vol.535
, pp. 153-158
-
-
Liu, X.1
-
84
-
-
84949091051
-
Gasdermin D is an executor of pyroptosis and required for interleukin 1β secretion
-
He, W. T. et al. Gasdermin D is an executor of pyroptosis and required for interleukin 1β secretion. Cell Res. 25, 1285-1298 (2015).
-
(2015)
Cell Res.
, vol.25
, pp. 1285-1298
-
-
He, W.T.1
-
85
-
-
84864774534
-
Sublytic concentrations of staphylococcus aureus panton-valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity
-
Graves, S. F. et al. Sublytic concentrations of Staphylococcus aureus Panton-Valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity. J. Leukoc. Biol. 92, 361-374 (2012).
-
(2012)
J. Leukoc. Biol.
, vol.92
, pp. 361-374
-
-
Graves, S.F.1
-
86
-
-
84890417859
-
Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps
-
Malachowa, N., Kobayashi, S. D., Freedman, B., Dorward, D. W. & DeLeo, F. R. Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps. J. Immunol. 191, 6022-6029 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 6022-6029
-
-
Malachowa, N.1
Kobayashi, S.D.2
Freedman, B.3
Dorward, D.W.4
DeLeo, F.R.5
-
87
-
-
84940873026
-
Counter inhibition between leukotoxins attenuates staphylococcus aureus virulence
-
Yoong, P. & Torres, V. J. Counter inhibition between leukotoxins attenuates Staphylococcus aureus virulence. Nat. Commun. 6, 8125 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 8125
-
-
Yoong, P.1
Torres, V.J.2
-
88
-
-
77950219265
-
Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia
-
Torres, V. J. et al. Staphylococcus aureus Fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infect. Immun. 78, 1618-1628 (2010).
-
(2010)
Infect. Immun.
, vol.78
, pp. 1618-1628
-
-
Torres, V.J.1
-
89
-
-
33845428586
-
Staphylococcus aureus IsdB is a hemoglobin receptor required for heme iron utilization
-
Torres, V. J., Pishchany, G., Humayun, M., Schneewind, O. & Skaar, E. P. Staphylococcus aureus IsdB is a hemoglobin receptor required for heme iron utilization. J. Bacteriol. 188, 8421-8429 (2006).
-
(2006)
J. Bacteriol.
, vol.188
, pp. 8421-8429
-
-
Torres, V.J.1
Pishchany, G.2
Humayun, M.3
Schneewind, O.4
Skaar, E.P.5
-
90
-
-
70349320391
-
Phenol-soluble modulin α3 enhances the human neutrophil lysis mediated by panton-valentine leukocidin
-
Hongo, I. et al. Phenol-soluble modulin α3 enhances the human neutrophil lysis mediated by Panton-Valentine leukocidin. J. Infect. Dis. 200, 715-723 (2009).
-
(2009)
J. Infect. Dis.
, vol.200
, pp. 715-723
-
-
Hongo, I.1
-
91
-
-
84961282143
-
Influence of sae regulated and agr-regulated factors on the escape of staphylococcus aureus from human macrophages
-
Munzenmayer, L. et al. Influence of Sae regulated and Agr-regulated factors on the escape of Staphylococcus aureus from human macrophages. Cell. Microbiol. 18, 1172-1183 (2016).
-
(2016)
Cell. Microbiol.
, vol.18
, pp. 1172-1183
-
-
Munzenmayer, L.1
-
92
-
-
0033053177
-
α-toxin and γ-toxin jointly promote staphylococcus aureus virulence in murine septic arthritis
-
Nilsson, I. M., Hartford, O., Foster, T. & Tarkowski, A. α-Toxin and γ-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis. Infect. Immun. 67, 1045-1049 (1999).
-
(1999)
Infect. Immun.
, vol.67
, pp. 1045-1049
-
-
Nilsson, I.M.1
Hartford, O.2
Foster, T.3
Tarkowski, A.4
-
93
-
-
0345487013
-
Assessment of the role of γ-toxin in experimental endophthalmitis using a hlg-deficient mutant of staphylococcus aureus
-
Supersac, G., Piemont, Y., Kubina, M., Prevost, G. & Foster, T. J. Assessment of the role of γ-toxin in experimental endophthalmitis using a hlg-deficient mutant of Staphylococcus aureus. Microb. Pathog. 24, 241-251 (1998).
-
(1998)
Microb. Pathog.
, vol.24
, pp. 241-251
-
-
Supersac, G.1
Piemont, Y.2
Kubina, M.3
Prevost, G.4
Foster, T.J.5
-
94
-
-
84940837106
-
Staphylococcus aureus biofilms induce macrophage dysfunction through leukocidin AB and alpha-toxin
-
15
-
Scherr, T. D. et al. Staphylococcus aureus biofilms induce macrophage dysfunction through leukocidin AB and alpha-toxin. mBio 6, e01021 15 (2015).
-
(2015)
MBio
, vol.6
, pp. e01021
-
-
Scherr, T.D.1
-
95
-
-
33845429616
-
Is panton-valentine leukocidin the major virulence determinant in community-associated methicillin-resistant staphylococcus aureus disease?
-
Voyich, J. M. et al. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J. Infect. Dis. 194, 1761-1770 (2006).
-
(2006)
J. Infect. Dis.
, vol.194
, pp. 1761-1770
-
-
Voyich, J.M.1
-
96
-
-
54749153168
-
Panton-valentine leukocidin is not a virulence determinant in murine models of community associated methicillin resistant staphylococcus aureus disease
-
Bubeck Wardenburg, J., Palazzolo Ballance, A. M., Otto, M., Schneewind, O. & DeLeo, F. R. Panton-Valentine leukocidin is not a virulence determinant in murine models of community associated methicillin resistant Staphylococcus aureus disease. J. Infect. Dis. 198, 1166-1170 (2008).
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 1166-1170
-
-
Bubeck Wardenburg, J.1
Palazzolo Ballance, A.M.2
Otto, M.3
Schneewind, O.4
DeLeo, F.R.5
-
97
-
-
76649119813
-
Antibody-mediated enhancement of community acquired methicillin resistant staphylococcus aureus infection
-
Yoong, P. & Pier, G. B. Antibody-mediated enhancement of community acquired methicillin resistant Staphylococcus aureus infection. Proc. Natl Acad. Sci. USA 107, 2241-2246 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 2241-2246
-
-
Yoong, P.1
Pier, G.B.2
-
98
-
-
80052221257
-
Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection
-
Kobayashi, S. D. et al. Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J. Infect. Dis. 204, 937-941 (2011).
-
(2011)
J. Infect. Dis.
, vol.204
, pp. 937-941
-
-
Kobayashi, S.D.1
-
99
-
-
84866904087
-
Staphylococcus aureus leukotoxin GH promotes inflammation
-
Malachowa, N. et al. Staphylococcus aureus leukotoxin GH promotes inflammation. J. Infect. Dis. 206, 1185-1193 (2012).
-
(2012)
J. Infect. Dis.
, vol.206
, pp. 1185-1193
-
-
Malachowa, N.1
-
100
-
-
84897894915
-
Staphylococcal bicomponent pore forming toxins: Targets for prophylaxis and immunotherapy
-
Aman, M. J. & Adhikari, R. P. Staphylococcal bicomponent pore forming toxins: targets for prophylaxis and immunotherapy. Toxins (Basel) 6, 950-972 (2014).
-
(2014)
Toxins (Basel)
, vol.6
, pp. 950-972
-
-
Aman, M.J.1
Adhikari, R.P.2
-
101
-
-
84958769064
-
Antibody based biologics and their promise to combat staphylococcus aureus infections
-
Sause, W. E., Buckley, P. T., Strohl, W. R., Lynch, A. S. & Torres, V. J. Antibody based biologics and their promise to combat Staphylococcus aureus infections. Trends Pharmacol. Sci. 37, 231-241 (2016).
-
(2016)
Trends Pharmacol. Sci.
, vol.37
, pp. 231-241
-
-
Sause, W.E.1
Buckley, P.T.2
Strohl, W.R.3
Lynch, A.S.4
Torres, V.J.5
-
102
-
-
80053625820
-
Heavy chain only antibodies and tetravalent bispecific antibody neutralizing staphylococcus aureus leukotoxins
-
Laventie, B. J. et al. Heavy chain only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins. Proc. Natl Acad. Sci. USA 108, 16404-16409 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 16404-16409
-
-
Laventie, B.J.1
-
103
-
-
84921376947
-
Five birds, one stone: Neutralization of α-hemolysin and 4 bi component leukocidins of staphylococcus aureus with a single human monoclonal antibody
-
Rouha, H. et al. Five birds, one stone: neutralization of α-hemolysin and 4 bi component leukocidins of Staphylococcus aureus with a single human monoclonal antibody. mAbs 7, 243-254 (2015).
-
(2015)
MAbs
, vol.7
, pp. 243-254
-
-
Rouha, H.1
-
104
-
-
84992365476
-
Improved protection in a rabbit model of community associated methicillin resistant staphylococcus aureus necrotizing pneumonia upon neutralization of leukocidins in addition to α-hemolysin
-
Diep, B. A. et al. Improved protection in a rabbit model of community associated methicillin resistant Staphylococcus aureus necrotizing pneumonia upon neutralization of leukocidins in addition to α-hemolysin. Antimicrob. Agents Chemother. 60, 6333-6340 (2016).
-
(2016)
Antimicrob. Agents Chemother
, vol.60
, pp. 6333-6340
-
-
Diep, B.A.1
-
105
-
-
85020217122
-
Monoclonal antibodies against the staphylococcus aureus bicomponent leukotoxin AB (LukAB) isolated following invasive human infection reveal diverse binding and modes of action
-
Thomsen, I. P. et al. Monoclonal antibodies against the Staphylococcus aureus bicomponent leukotoxin AB (LukAB) isolated following invasive human infection reveal diverse binding and modes of action. J. Infect. Dis. http://dx.doi.org/10.1093/infdis/jix071 (2017).
-
(2017)
J. Infect. Dis.
-
-
Thomsen, I.P.1
-
106
-
-
72049129173
-
Immunogenicity of toxins during staphylococcus aureus infection
-
Verkaik, N. J. et al. Immunogenicity of toxins during Staphylococcus aureus infection. Clin. Infect. Dis. 50, 61-68 (2010).
-
(2010)
Clin. Infect. Dis.
, vol.50
, pp. 61-68
-
-
Verkaik, N.J.1
-
107
-
-
84865737411
-
Lower antibody levels to staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. Aureus infections
-
Adhikari, R. P. et al. Lower antibody levels to Staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. aureus infections. J. Infect. Dis. 206, 915-923 (2012).
-
(2012)
J. Infect. Dis.
, vol.206
, pp. 915-923
-
-
Adhikari, R.P.1
-
108
-
-
78349254278
-
High levels of antibody to panton-valentine leukocidin are not associated with resistance to staphylococcus aureus-associated skin and soft tissue infection
-
Hermos, C. R., Yoong, P. & Pier, G. B. High levels of antibody to Panton-Valentine leukocidin are not associated with resistance to Staphylococcus aureus-associated skin and soft tissue infection. Clin. Infect. Dis. 51, 1138-1146 (2010).
-
(2010)
Clin. Infect. Dis.
, vol.51
, pp. 1138-1146
-
-
Hermos, C.R.1
Yoong, P.2
Pier, G.B.3
-
109
-
-
62149104852
-
The panton-valentine leukocidin vaccine protects mice against lung and skin infections caused by staphylococcus aureus USA300
-
Brown, E. L. et al. The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin. Microbiol. Infect. 15, 156-164 (2009).
-
(2009)
Clin. Microbiol. Infect.
, vol.15
, pp. 156-164
-
-
Brown, E.L.1
-
110
-
-
84878764873
-
Structurally designed attenuated subunit vaccines for S. Aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model
-
Karauzum, H. et al. Structurally designed attenuated subunit vaccines for S. aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model. PLoS ONE 8, e65384 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e65384
-
-
Karauzum, H.1
-
111
-
-
84907066000
-
Models matter: The search for an effective staphylococcus aureus vaccine
-
Salgado-Pabon, W. & Schlievert, P. M. Models matter: the search for an effective Staphylococcus aureus vaccine. Nat. Rev. Microbiol. 12, 585-591 (2014).
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 585-591
-
-
Salgado-Pabon, W.1
Schlievert, P.M.2
-
112
-
-
84859424015
-
Is there a future for a staphylococcus aureus vaccine?
-
Proctor, R. A. Is there a future for a Staphylococcus aureus vaccine? Vaccine 30, 2921-2927 (2012).
-
(2012)
Vaccine
, vol.30
, pp. 2921-2927
-
-
Proctor, R.A.1
-
113
-
-
84948961540
-
Increased susceptibility of humanized NSG mice to panton-valentine leukocidin and staphylococcus aureus skin infection
-
Tseng, C. W. et al. Increased susceptibility of humanized NSG mice to Panton-Valentine leukocidin and Staphylococcus aureus skin infection. PLoS Pathog. 11, e1005292 (2015).
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1005292
-
-
Tseng, C.W.1
-
114
-
-
85021989813
-
Humanized mice exhibit increased susceptibility to staphylococcus aureus pneumonia
-
Prince, A., Wang, H., Kitur, K. & Parker, D. Humanized mice exhibit increased susceptibility to Staphylococcus aureus pneumonia. J. Infect. Dis. http://dx.doi.org/10.1093/infdis/jiw425 (2016).
-
(2016)
J. Infect. Dis.
-
-
Prince, A.1
Wang, H.2
Kitur, K.3
Parker, D.4
-
115
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
Yang, H. et al. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154, 1370-1379 (2013).
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
-
116
-
-
84855808422
-
Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo
-
Alonzo, F. III et al. Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo. Mol. Microbiol. 83, 423-435 (2012).
-
(2012)
Mol. Microbiol.
, vol.83
, pp. 423-435
-
-
Alonzo, F.1
-
117
-
-
84982253941
-
Analysis of protein coding genetic variation in 60,706 humans
-
Lek, M. et al. Analysis of protein coding genetic variation in 60,706 humans. Nature 536, 285-291 (2016).
-
(2016)
Nature
, vol.536
, pp. 285-291
-
-
Lek, M.1
-
118
-
-
84859266795
-
Livestock-associated staphylococcus aureus: Origin, evolution and public health threat
-
Fitzgerald, J. R. Livestock-associated Staphylococcus aureus: origin, evolution and public health threat. Trends Microbiol. 20, 192-198 (2012).
-
(2012)
Trends Microbiol.
, vol.20
, pp. 192-198
-
-
Fitzgerald, J.R.1
-
119
-
-
84999040132
-
LukMF' is the major secreted leukocidin of bovine staphylococcus aureus and is produced in vivo during bovine mastitis
-
Vrieling, M. et al. LukMF' is the major secreted leukocidin of bovine Staphylococcus aureus and is produced in vivo during bovine mastitis. Sci. Rep. 6, 37759 (2016).
-
(2016)
Sci. Rep.
, vol.6
, pp. 37759
-
-
Vrieling, M.1
-
120
-
-
0036899166
-
Biological and biomedical implications of the co evolution of pathogens and their hosts
-
Woolhouse, M. E., Webster, J. P., Domingo, E., Charlesworth, B. & Levin, B. R. Biological and biomedical implications of the co evolution of pathogens and their hosts. Nat. Genet. 32, 569-577 (2002).
-
(2002)
Nat. Genet.
, vol.32
, pp. 569-577
-
-
Woolhouse, M.E.1
Webster, J.P.2
Domingo, E.3
Charlesworth, B.4
Levin, B.R.5
-
121
-
-
79961136139
-
Panton-valentine leukocidin does play a role in the early stage of staphylococcus aureus skin infections: A rabbit model
-
Lipinska, U. et al. Panton-Valentine leukocidin does play a role in the early stage of Staphylococcus aureus skin infections: a rabbit model. PLoS ONE 6, e22864 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e22864
-
-
Lipinska, U.1
-
122
-
-
0027955508
-
Staphylococcal scalded skin syndrome in adults. A clinical review illustrated with a new case
-
Cribier, B., Piemont, Y. & Grosshans, E. Staphylococcal scalded skin syndrome in adults. A clinical review illustrated with a new case. J. Am. Acad. Dermatol. 30, 319-324 (1994).
-
(1994)
J. Am. Acad. Dermatol.
, vol.30
, pp. 319-324
-
-
Cribier, B.1
Piemont, Y.2
Grosshans, E.3
-
123
-
-
70349744042
-
Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant staphylococcus aureus rabbit osteomyelitis
-
Cremieux, A. C. et al. Panton-Valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS ONE 4, e7204 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e7204
-
-
Cremieux, A.C.1
-
124
-
-
77950379429
-
Polymorphonuclear leukocytes mediate staphylococcus aureus panton-valentine leukocidin-induced lung inflammation and injury
-
Diep, B. A. et al. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc. Natl Acad. Sci. USA 107, 5587-5592 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5587-5592
-
-
Diep, B.A.1
-
125
-
-
52449088546
-
Contribution of panton-valentine leukocidin in community associated methicillin resistant staphylococcus aureus pathogenesis
-
Diep, B. A. et al. Contribution of Panton-Valentine leukocidin in community associated methicillin resistant Staphylococcus aureus pathogenesis. PLoS ONE 3, e3198 (2008).
-
(2008)
PLoS ONE
, vol.3
, pp. e3198
-
-
Diep, B.A.1
-
126
-
-
33750291381
-
International dissemination of a high virulence rabbit staphylococcus aureus clone
-
Vancraeynest, D. et al. International dissemination of a high virulence rabbit Staphylococcus aureus clone. J. Vet. Med. B Infect. Dis. Vet. Public Health 53, 418-422 (2006).
-
(2006)
J. Vet. Med. B Infect. Dis. Vet. Public Health
, vol.53
, pp. 418-422
-
-
Vancraeynest, D.1
|