The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors

Nature Communications

Volumn 5, Issue , 2014, Pages

  Spaan, András N ^a,b,c   Vrieling, Manouk ^a   Wallet, Pierre ^b,c,d   Badiou, Cédric ^b,c,d   Reyes Robles, Tamara ^e   Ohneck, Elizabeth A ^e   Benito, Yvonne ^b,c,d,f   De Haas, Carla J C ^a   Day, Christopher J ^g   Jennings, Michael P ^g   Lina, Gérard ^b,c,d,f   Vandenesch, Franҫois ^b,c,d,f   Van Kessel, Kok P M ^a   Torres, Victor J ^e   Van Strijp, Jos A G ^a   Henry, Thomas ^b,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^c INSERM   (France)

^d CNRS   (France)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f HOSPICES CIVILS DE LYON   (France)

^g GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL RNA; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR4; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5L2 RECEPTOR; COMPLEMENT RECEPTOR; GAMMA HEMOLYSIN AB; GAMMA HEMOLYSIN CB; STAPHYLOCOCCUS TOXIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; CHEMOKINE RECEPTOR; GAMMA-HEMOLYSIN, STAPHYLOCOCCUS AUREUS; HEMOLYSIN;

GENE EXPRESSION; GERM CELL; MICROBIAL ACTIVITY; PATHOGEN; SECRETION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; CALCIUM MOBILIZATION ASSAY; CELL MEMBRANE PERMEABILITY; CELL SPECIFICITY; CHANNEL GATING; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; LEUKOCYTE; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PHAGOCYTE; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SURFACE PLASMON RESONANCE; ANIMAL; C57BL MOUSE; CELL CULTURE; DEFICIENCY; DISEASE MODEL; FEMALE; GENETICS; KNOCKOUT MOUSE; MALE; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

MURINAE; STAPHYLOCOCCUS AUREUS;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; HEMOLYSIN PROTEINS; HUMANS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERITONITIS; PHAGOCYTES; RECEPTORS, CCR2; RECEPTORS, CHEMOKINE; RECEPTORS, COMPLEMENT; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84925274771     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6438     Document Type: Article

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