메뉴 건너뛰기




Volumn 6, Issue 1, 2010, Pages

Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils

Author keywords

[No Author keywords available]

Indexed keywords

PANTON VALENTINE LEUKOCIDIN; VIRULENCE FACTOR; BACTERIAL TOXIN; EXOTOXIN; LEUKOCIDIN; PANTON-VALENTINE LEUKOCIDIN;

EID: 77649223154     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000715     Document Type: Article
Times cited : (350)

References (34)
  • 1
    • 0032551901 scopus 로고    scopus 로고
    • Staphylococcus aureus infections
    • Lowy FD (1998) Staphylococcus aureus infections. N Engl J Med 339: 520-532.
    • (1998) N Engl J Med , vol.339 , pp. 520-532
    • Lowy, F.D.1
  • 2
    • 44149098644 scopus 로고    scopus 로고
    • Pathogenesis of methicillin-resistant Staphylococcus aureus infection
    • Gordon RJ, Lowy FD (2008) Pathogenesis of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis 46 Suppl 5: S350-S359.
    • (2008) Clin Infect Dis , vol.46 , Issue.SUPPL. 5
    • Gordon, R.J.1    Lowy, F.D.2
  • 3
    • 33144454355 scopus 로고    scopus 로고
    • Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections
    • King MD, Humphrey BJ, Wang YF, Kourbatova EV, Ray SM, et al. (2006) Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann Intern Med 144: 309-317.
    • (2006) Ann Intern Med , vol.144 , pp. 309-317
    • King, M.D.1    Humphrey, B.J.2    Wang, Y.F.3    Kourbatova, E.V.4    Ray, S.M.5
  • 4
    • 0037006653 scopus 로고    scopus 로고
    • Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
    • Gillet Y, Issartel B, Vanhems P, Fournet JC, Lina G, et al. (2002) Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 359: 753-759.
    • (2002) Lancet , vol.359 , pp. 753-759
    • Gillet, Y.1    Issartel, B.2    Vanhems, P.3    Fournet, J.C.4    Lina, G.5
  • 5
    • 44149101259 scopus 로고    scopus 로고
    • Pneumonia caused by methicillinresistant Staphylococcus aureus
    • Rubinstein E, Kollef MH, Nathwani D (2008) Pneumonia caused by methicillinresistant Staphylococcus aureus. Clin Infect Dis 46 Suppl 5: S378-S385.
    • (2008) Clin Infect Dis , vol.46 , Issue.SUPPL. 5
    • Rubinstein, E.1    Kollef, M.H.2    Nathwani, D.3
  • 6
    • 0033496604 scopus 로고    scopus 로고
    • Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia
    • Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, et al. (1999) Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 29: 1128-1132.
    • (1999) Clin Infect Dis , vol.29 , pp. 1128-1132
    • Lina, G.1    Piemont, Y.2    Godail-Gamot, F.3    Bes, M.4    Peter, M.O.5
  • 7
    • 0001495098 scopus 로고
    • Purification of the two components of leucocidin from Staphylococcus aureus
    • Woodin AM (1960) Purification of the two components of leucocidin from Staphylococcus aureus. Biochem J 75: 158-165.
    • (1960) Biochem J , vol.75 , pp. 158-165
    • Woodin, A.M.1
  • 8
    • 30944450373 scopus 로고    scopus 로고
    • Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002
    • Kuehnert MJ, Kruszon-Moran D, Hill HA, McQuillan G, McAllister SK, et al. (2006) Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002. J Infect Dis 193: 172-179.
    • (2006) J Infect Dis , vol.193 , pp. 172-179
    • Kuehnert, M.J.1    Kruszon-Moran, D.2    Hill, H.A.3    McQuillan, G.4    McAllister, S.K.5
  • 9
    • 33847309856 scopus 로고    scopus 로고
    • Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia
    • Labandeira-Rey M, Couzon F, Boisset S, Brown EL, Bes M, et al. (2007) Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 315: 1130-1133.
    • (2007) Science , vol.315 , pp. 1130-1133
    • Labandeira-Rey, M.1    Couzon, F.2    Boisset, S.3    Brown, E.L.4    Bes, M.5
  • 10
    • 36849064891 scopus 로고    scopus 로고
    • Poring over pores: Alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia
    • Bubeck WJ, Bae T, Otto M, Deleo FR, Schneewind O (2007) Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med 13: 1405-1406.
    • (2007) Nat Med , vol.13 , pp. 1405-1406
    • Bubeck, W.J.1    Bae, T.2    Otto, M.3    Deleo, F.R.4    Schneewind, O.5
  • 11
    • 33846814907 scopus 로고    scopus 로고
    • Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia
    • Bubeck WJ, Patel RJ, Schneewind O (2007) Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect Immun 75: 1040-1044.
    • (2007) Infect Immun , vol.75 , pp. 1040-1044
    • Bubeck, W.J.1    Patel, R.J.2    Schneewind, O.3
  • 12
    • 33845429616 scopus 로고    scopus 로고
    • Is Panton-Valentine leukocidin the major virulence determinant in communityassociated methicillin-resistant Staphylococcus aureus disease?
    • Voyich JM, Otto M, Mathema B, Braughton KR, Whitney AR, et al. (2006) Is Panton-Valentine leukocidin the major virulence determinant in communityassociated methicillin-resistant Staphylococcus aureus disease? J Infect Dis 194: 1761-1770.
    • (2006) J Infect Dis , vol.194 , pp. 1761-1770
    • Voyich, J.M.1    Otto, M.2    Mathema, B.3    Braughton, K.R.4    Whitney, A.R.5
  • 13
    • 0025787798 scopus 로고
    • Alpha-toxin of Staphylococcus aureus
    • Bhakdi S, Tranum-Jensen J (1991) Alpha-toxin of Staphylococcus aureus. Microbiol Rev 55: 733-751.
    • (1991) Microbiol Rev , vol.55 , pp. 733-751
    • Bhakdi, S.1    Tranum-Jensen, J.2
  • 14
    • 30544444128 scopus 로고    scopus 로고
    • Immune evasion by staphylococci
    • Foster TJ (2005) Immune evasion by staphylococci. Nat Rev Microbiol 3: 948-958.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 948-958
    • Foster, T.J.1
  • 16
    • 36849049884 scopus 로고    scopus 로고
    • Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA
    • Wang R, Braughton KR, Kretschmer D, Bach TH, Queck SY, et al. (2007) Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med 13: 1510-1514.
    • (2007) Nat Med , vol.13 , pp. 1510-1514
    • Wang, R.1    Braughton, K.R.2    Kretschmer, D.3    Bach, T.H.4    Queck, S.Y.5
  • 18
    • 27644538026 scopus 로고    scopus 로고
    • Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils
    • Genestier AL, Michallet MC, Prevost G, Bellot G, Chalabreysse L, et al. (2005) Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils. J Clin Invest 115: 3117-3127.
    • (2005) J Clin Invest , vol.115 , pp. 3117-3127
    • Genestier, A.L.1    Michallet, M.C.2    Prevost, G.3    Bellot, G.4    Chalabreysse, L.5
  • 19
    • 33745983268 scopus 로고    scopus 로고
    • Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains
    • Gomez MI, O'Seaghdha M, Magargee M, Foster TJ, Prince AS (2006) Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains. J Biol Chem 281: 20190-20196.
    • (2006) J Biol Chem , vol.281 , pp. 20190-20196
    • Gomez, M.I.1    O'Seaghdha, M.2    Magargee, M.3    Foster, T.J.4    Prince, A.S.5
  • 20
    • 0141614012 scopus 로고    scopus 로고
    • Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: Role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway
    • Haslinger B, Strangfeld K, Peters G, Schulze-Osthoff K, Sinha B (2003) Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway. Cell Microbiol 5: 729-741.
    • (2003) Cell Microbiol , vol.5 , pp. 729-741
    • Haslinger, B.1    Strangfeld, K.2    Peters, G.3    Schulze-Osthoff, K.4    Sinha, B.5
  • 21
    • 58149178679 scopus 로고    scopus 로고
    • Host defense and pathogenesis in Staphylococcus aureus infections
    • Deleo FR, Diep BA, Otto M (2009) Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am 23: 17-34.
    • (2009) Infect Dis Clin North Am , vol.23 , pp. 17-34
    • Deleo, F.R.1    Diep, B.A.2    Otto, M.3
  • 22
    • 0041707781 scopus 로고    scopus 로고
    • Elucidation of molecular events leading to neutrophil apoptosis following phagocytosis: Cross-talk between caspase 8, reactive oxygen species, and MAPK/ERK activation
    • Zhang B, Hirahashi J, Cullere X, Mayadas TN (2003) Elucidation of molecular events leading to neutrophil apoptosis following phagocytosis: cross-talk between caspase 8, reactive oxygen species, and MAPK/ERK activation. J Biol Chem 278: 28443-28454.
    • (2003) J Biol Chem , vol.278 , pp. 28443-28454
    • Zhang, B.1    Hirahashi, J.2    Cullere, X.3    Mayadas, T.N.4
  • 23
    • 54749153168 scopus 로고    scopus 로고
    • Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease
    • Bubeck WJ, Palazzolo-Ballance AM, Otto M, Schneewind O, Deleo FR (2008) Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. J Infect Dis 198: 1166-1170.
    • (2008) J Infect Dis , vol.198 , pp. 1166-1170
    • Bubeck, W.J.1    Palazzolo-Ballance, A.M.2    Otto, M.3    Schneewind, O.4    Deleo, F.R.5
  • 24
    • 22144483435 scopus 로고    scopus 로고
    • Differential distribution and expression of Panton-Valentine leucocidin among community-acquired methicillin-resistant Staphylococcus aureus strains
    • Said-Salim B, Mathema B, Braughton K, Davis S, Sinsimer D, et al. (2005) Differential distribution and expression of Panton-Valentine leucocidin among community-acquired methicillin-resistant Staphylococcus aureus strains. J Clin Microbiol 43: 3373-3379.
    • (2005) J Clin Microbiol , vol.43 , pp. 3373-3379
    • Said-Salim, B.1    Mathema, B.2    Braughton, K.3    Davis, S.4    Sinsimer, D.5
  • 25
    • 34447567495 scopus 로고    scopus 로고
    • A global view of Staphylococcus aureus whole genome expression upon internalization in human epithelial cells
    • Garzoni C, Francois P, Huyghe A, Couzinet S, Tapparel C, et al. (2007) A global view of Staphylococcus aureus whole genome expression upon internalization in human epithelial cells. BMC Genomics 8: 171.
    • (2007) BMC Genomics , vol.8 , pp. 171
    • Garzoni, C.1    Francois, P.2    Huyghe, A.3    Couzinet, S.4    Tapparel, C.5
  • 26
    • 77649214418 scopus 로고    scopus 로고
    • ed () Gram-Positive Pathogens. Washington: ASM Press. pp
    • Arvidson S (2006) Extracellular Enzymes. In: Fischetti VA, ed (2006) Gram-Positive Pathogens. Washington: ASM Press. pp 478-516.
    • (2006) Extracellular Enzymes , pp. 478-516
    • Arvidson, S.1
  • 27
    • 58849131103 scopus 로고    scopus 로고
    • Virulence gene expression in human community-acquired Staphylococcus aureus infection
    • Loughman JA, Fritz SA, Storch GA, Hunstad DA (2009) Virulence gene expression in human community-acquired Staphylococcus aureus infection. J Infect Dis 199: 294-301.
    • (2009) J Infect Dis , vol.199 , pp. 294-301
    • Loughman, J.A.1    Fritz, S.A.2    Storch, G.A.3    Hunstad, D.A.4
  • 28
    • 40449127435 scopus 로고    scopus 로고
    • In vitro production of panton-valentine leukocidin among strains of methicillin-resistant Staphylococcus aureus causing diverse infections
    • Hamilton SM, Bryant AE, Carroll KC, Lockary V, Ma Y, et al. (2007) In vitro production of panton-valentine leukocidin among strains of methicillin-resistant Staphylococcus aureus causing diverse infections. Clin Infect Dis 45: 1550-1558.
    • (2007) Clin Infect Dis , vol.45 , pp. 1550-1558
    • Hamilton, S.M.1    Bryant, A.E.2    Carroll, K.C.3    Lockary, V.4    Ma, Y.5
  • 29
    • 0023151784 scopus 로고
    • Improvment of protoplast trasnformation in Staphylococcus carnosus
    • Götz F, Schumacher B (1987) Improvment of protoplast trasnformation in Staphylococcus carnosus. FEMS Immunol Med Microbiol 40: 285-288.
    • (1987) FEMS Immunol Med Microbiol , vol.40 , pp. 285-288
    • Götz, F.1    Schumacher, B.2
  • 30
    • 0034443264 scopus 로고    scopus 로고
    • Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells
    • Sinha B, Francois P, Que YA, Hussain M, Heilmann C, et al. (2000) Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect Immun 68: 6871-6878.
    • (2000) Infect Immun , vol.68 , pp. 6871-6878
    • Sinha, B.1    Francois, P.2    Que, Y.A.3    Hussain, M.4    Heilmann, C.5
  • 31
    • 0028094702 scopus 로고
    • Gentamicinresistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells
    • Balwit JM, van Langevelde P, Vann JM, Proctor RA (1994) Gentamicinresistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells. J Infect Dis 170: 1033-1037.
    • (1994) J Infect Dis , vol.170 , pp. 1033-1037
    • Balwit, J.M.1    van Langevelde, P.2    Vann, J.M.3    Proctor, R.A.4
  • 32
    • 0034665906 scopus 로고    scopus 로고
    • Protein A is the von Willebrand factor binding protein on Staphylococcus aureus
    • Hartleib J, Kohler N, Dickinson RB, Chhatwal GS, Sixma JJ, et al. (2000) Protein A is the von Willebrand factor binding protein on Staphylococcus aureus. Blood 96: 2149-2156.
    • (2000) Blood , vol.96 , pp. 2149-2156
    • Hartleib, J.1    Kohler, N.2    Dickinson, R.B.3    Chhatwal, G.S.4    Sixma, J.J.5
  • 33
    • 0141614012 scopus 로고    scopus 로고
    • Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: Role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway
    • Haslinger B, Strangfeld K, Peters G, Schulze-Osthoff K, Sinha B (2003) Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway. Cell Microbiol 5: 729-41.
    • (2003) Cell Microbiol , vol.5 , pp. 729-741
    • Haslinger, B.1    Strangfeld, K.2    Peters, G.3    Schulze-Osthoff, K.4    Sinha, B.5
  • 34
    • 0034460335 scopus 로고    scopus 로고
    • Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock
    • Reichardt HM, Umland T, Bauer A, Kretz O, Schutz G (2000) Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock. Mol Cell Biol 20: 9009-17.
    • (2000) Mol Cell Biol , vol.20 , pp. 9009-9017
    • Reichardt, H.M.1    Umland, T.2    Bauer, A.3    Kretz, O.4    Schutz, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.