Staphylococcus aureus biofilms induce macrophage dysfunction through leukocidin AB and alpha-toxin

mBio

Volumn 6, Issue 4, 2015, Pages

  Scherr, Tyler D ^a   Hanke, Mark L ^a,d   Huang, Ouwen ^a   James, David B A ^b   Horswill, Alexander R ^c   Bayles, Kenneth W ^a   Fey, Paul D ^a   Torres, Victor J ^b   Kielian, Tammy ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d MALLINCKRODT PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM10 ENDOPEPTIDASE; ALPHA TOXIN; HLA ANTIBODY; LEUKOCIDIN; LEUKOCIDIN AB; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; CONDITIONED MEDIUM; HEMOLYSIN; LEUKOCIDIN AB, STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCAL ALPHA-TOXIN;

AGE; AGR GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GENE; BACTERIAL STRAIN; BIOFILM; CELL DAMAGE; CONFORMATION; CONTROLLED STUDY; CYTOTOXICITY; FOOD DEPRIVATION; GENETIC COMPLEMENTATION; HLA GENE; HUMAN; IN VIVO STUDY; LUKAB GENE; MACROPHAGE; MACROPHAGE DYSFUNCTION; MALE; MASS SPECTROMETRY; MOUSE; MUTANT; NONHUMAN; NUTRITIONAL TOLERANCE; ORTHOPEDIC IMPLANT; PATHOGEN LOAD; PHAGOCYTOSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STAPHYLOCOCCUS AUREUS; ANIMAL; CONDITIONED MEDIUM; DISEASE MODEL; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MUTATION; PHYSIOLOGY; STAPHYLOCOCCUS INFECTION;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BIOFILMS; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; HEMOLYSIN PROTEINS; HUMANS; LEUKOCIDINS; MACROPHAGES; MICE; MUTATION; PHAGOCYTOSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84940837106     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01021-15     Document Type: Article

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