Structure-function analysis of Heterodimer Formation, oligomerization, and receptor binding of the staphylococcus aureus bi-component toxin LukGH

Journal of Biological Chemistry

Volumn 290, Issue 1, 2015, Pages 142-156

  Badarau, Adriana ^a   Rouha, Harald ^a   Malafa, Stefan ^a   Logan, Derek T ^b   Håkansson, Maria ^b   Stulik, Lukas ^a   Dolezilkova, Ivana ^a   Teubenbacher, Astrid ^a   Gross, Karin ^a   Maierhofer, Barbara ^a   Weber, Susanne ^a   Jägerhofer, Michaela ^a   Hoffman, David ^a   Nagy, Eszter ^a  

^a Vienna Biocenter   (Austria)

^b SARomics Biostructures AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; BIOMOLECULES; CELLS; CYTOLOGY; INTERFEROMETRY; LIGHT SCATTERING; OLIGOMERS; TOXIC MATERIALS;

AMINO ACID SEQUENCE; DYNAMIC LIGHT SCATTERING MEASUREMENT; HETERODIMER FORMATION; INTRINSIC TRYPTOPHAN FLUORESCENCES; OCTAMERIC STRUCTURE; STAPHYLOCOCCUS AUREUS; STRUCTURAL DIFFERENCES; STRUCTURE-FUNCTION ANALYSIS;

X RAY CRYSTALLOGRAPHY;

ALANINE; ARGININE; ASPARTIC ACID; BACTERIAL TOXIN; CD11B ANTIGEN; GLUTAMIC ACID; GLYCINE; HETERODIMER; LUKGH TOXIN; LYSINE; METHIONINE; THREONINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; HEMOLYSIN; ITGAM PROTEIN, HUMAN; LEUKOCIDIN; LEUKOCIDIN AB, STAPHYLOCOCCUS AUREUS; PROTEIN BINDING; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CYTOLYSIS; DIMERIZATION; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; INTERFEROMETRY; LIGHT SCATTERING; NONHUMAN; OLIGOMERIZATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; TOXIN ANALYSIS; TOXIN STRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMISTRY; HL-60 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; MOUSE; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD11B; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HEMOLYSIN PROTEINS; HL-60 CELLS; HUMANS; LEUKOCIDINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84920531939     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.598110     Document Type: Article

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